Abstract: A compound, as represented by formula I, as a TLR7 agonist, a method for preparing the compound, and the use of the compound in treating diseases mediated by the TLR7 agonist are provided. Studies on the activity of a human-derived receptor, a TLR7 agonist, show that compounds have a strong agonistic effect on the human-derived receptor, TLR7, and can be used as a foreground compound for treating diseases mediated by the TLR7 agonist.

Abstract: Provided are a preparation method for a CTL cell and an application thereof. The preparation method comprises the following steps of: inducing a CTL cell by using a tumor antigen PAP-GM-CSF sensitized DC cell; and knocking out a PD-1 gene of the CTL cell to obtain a PD-1 knock-out CTL cell. The CTL cell obtained by the preparation method can be used for preparing drugs for treatment of prostate cancer, especially for treating PAP-positive prostate cancer. The CTL cell does not cause CTL cell failure and anergy due to the tumor-expressed PD-L1 after being transfused into the body, thereby producing efficient specific cytotoxic effect on a tumor cell and improving the curative effect and reducing the side effect.

Abstract: A rendering method includes that a physical engine on a remote computing platform obtains a physical simulation result based on an operation instruction sent by a user corresponding to a first rendering engine or a user corresponding to a second rendering engine, and then sends the physical simulation result to the first rendering engine and the second rendering engine, so that the first rendering engine performs rendering based on the physical simulation result to obtain a first rendered image, and the second rendering engine performs rendering based on the physical simulation result to obtain a second rendered image, where the operation instruction affects at least one three-dimensional model in a target scene, and the physical simulation result includes physical information of the at least one three-dimensional model affected by the operation instruction.

Abstract: The present disclosure provides a cooling structure of heat pipe for superconducting magneto plasma dynamic thruster having a cylindrical structure and includes a cathode, an intermediate connector and an anode. The cathode is arranged inside the intermediate connector, the anode is arranged outside the intermediate connector; the cathode is provided with a cathode cooling mechanism, and the anode is provided with an anode cooling mechanism. The cathode cooling mechanism includes a cathode heat pipe and a cathode heat dissipation fin. The anode heat pipe cooling mechanism includes an anode heat pipe and an anode heat dissipation fin.

Abstract: The present disclosure provides a cooling structure of heat pipe for superconducting magneto plasma dynamic thruster having a cylindrical structure and includes a cathode, an intermediate connector and an anode. The cathode is arranged inside the intermediate connector, the anode is arranged outside the intermediate connector; the cathode is provided with a cathode cooling mechanism, and the anode is provided with an anode cooling mechanism. The cathode cooling mechanism includes a cathode heat pipe and a cathode heat dissipation fin. The anode heat pipe cooling mechanism includes an anode heat pipe and an anode heat dissipation fin.