Patents by Inventor Zhoufeng Chen

Zhoufeng Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artery - and vein-specific proteins and uses therefor
    Publication number: 20010024650
    Abstract: Arterial and venous endothelial cells are molecularly distinct from the earliest stages of angiogenesis. This distinction is revealed by expression on arterial cells of a transmembrane ligand, called EphrinB2 whose receptor EphB4 is expressed on venous cells. Targeted disruption of the EphrinB2 gene prevents the remodeling of veins from a capillary plexus into properly branched structures. Moreover, it also disrupts the remodeling of arteries, suggesting that reciprocal interactions between pre-specified arterial and venous endothelial cells are necessary for angiogenesis.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 27, 2001
    Inventors: Hai U. Wang, Zhoufeng Chen, David J. Anderson