Patents by Inventor Zhu Chen

Zhu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200157822
    Abstract: Flooring material has an anti-slip, noise reducing pad directly self-adhered to a bottom surface. The pad is formed by applying a foamable PVC material is directly on the bottom surface of the flooring and heating the PVC material to foam the PVC material. The PVC material may then be cooled to form the pad with a definite formed shape having a resilient outer surface layer and a spongy foamy inner structure.
    Type: Application
    Filed: January 7, 2019
    Publication date: May 21, 2020
    Inventor: Zhu Chen
  • Patent number: 10584179
    Abstract: Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: March 10, 2020
    Assignees: Merck Sharp & Dohme Corp., Adimab, LLC
    Inventors: Zhu Chen, Kenneth P. Ellsworth, James A. Milligan, Elizabeth Oldham, Dietmar Seiffert, Vaishnavi Ganti, Mohammad Tabrizifard, Bianka Prinz
  • Publication number: 20190354716
    Abstract: A real-time event processing system receives event data containing telemetric data and one or more personal identifiers. The personal identifier in the event data is replaced with an obfuscated value so that the telemetric data may be used without reference to the personal identifier. A reversible map is used to reverse the obfuscated personal identifier to its original value. In the case when a request is received to delete the mapped personal identifier, the link to the entry in the reversible map is broken by associating the personal identifier with a different obfuscated value.
    Type: Application
    Filed: December 10, 2018
    Publication date: November 21, 2019
    Inventors: SHIBANI BASAVA, DINESH CHANDNANI, ZHU CHEN, RAM KUMAR DONTHULA, MATTHEW SLOAN THEODORE EVANS, SIWEI LI, GEORGE JOSHUA MICHAELS, ANDREW CHRISTOPHER NEIL, GEOFFREY STANEFF, EVGENIA STESHENKO, VIJAY UPADYA, SHENGYU FU
  • Publication number: 20190354717
    Abstract: A rule-based attribution mechanism analyzes documents having different types of data in different formats through the application of script-based rules that apply a tag to the document identifying the type of sensitive data that is contained in the document. Documents having similar tags are aggregated so that the sensitive data is scrubbed from the document leaving the telemetric data available for downstream processing. The scrubbing entails different actions, such as, eliminating the sensitive data, obfuscating the sensitive data, and converting the sensitive data into a non-sensitive value.
    Type: Application
    Filed: May 9, 2019
    Publication date: November 21, 2019
    Inventors: BRIAN BOON, DINESH CHANDNANI, ZHU CHEN, RAM KUMAR DONTHULA, MATTHEW SLOAN THEODORE EVANS, ANDREW NEIL, VIJAYA UPADYA, GEOFFREY STANEFF, SHIBANI BASAVA, EVGENIA STESHENKO, CARL BROCHU, SHAUN MILLER, XIN SHI
  • Publication number: 20190270982
    Abstract: A method for screening aptamers by using a microarray microfluidic chip. The screening chip integrates microarray and microfluidic technology to integrate the positive and negative screening process on a microfluidic chip, and obtains aptamers with high affinity after 7 rounds of screening. At the same time, the present invention also discloses specific steps for screening of lactoferrin aptamers, including detailed processes such as chip preparation, positive and negative screening processes, and PCR amplification. The aptamers screened by the method have good specificity and affinity to the target protein. The aptamers are easier to be obtained than the antibody, and can be synthesized rapidly in large quantities in vitro. The preparation method is simpler and faster, so aptamers are expected to be a useful complement to antibody technology in many areas.
    Type: Application
    Filed: February 7, 2017
    Publication date: September 5, 2019
    Inventors: Danke XU, Hui LI, Xiaohui LIU, Zhu CHEN
  • Publication number: 20180362661
    Abstract: Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 20, 2018
    Applicants: Merck Sharp & Dohme Corp,, Adimab, LLC
    Inventors: Zhu Chen, Kenneth Ellsworth, James A. Milligan, Elizabeth Oldham, Dietmar Seiffert, Vaishnavi Ganti, Mohammad Tabritzifard, Bianka Prinz
  • Patent number: 10094124
    Abstract: An engineered plank material and a method for making the plank material are disclosed. The plank material includes a veneer that is made out of plant material, and includes a nonwoven fabric or fiberglass mesh adhered to an inward-facing portion of the veneer. The plank material includes an adhesive paper material including macromolecular glue, which is between the veneer and a third layer of the plank material, which is constructed from one of bamboo, wood, or paper. The plank material then includes a fourth layer which is an adhesive paper material including a micromolecular glue. These layers are compressed together at a high heat and a high pressure in order to form the plank material.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: October 9, 2018
    Assignee: WELLMADE FLOOR COVERING INT'L INC.
    Inventors: Ming Chen, Zhu Chen
  • Patent number: 10053515
    Abstract: Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: August 21, 2018
    Assignees: Merck Sharp & Dohme Corp., Adimab LLC
    Inventors: Zhu Chen, Kenneth P. Ellsworth, James A. Milligan, Elizabeth Oldham, Dietmar Seiffert, Vaishnavi Ganti, Mohammad Tabrizifard, Bianka Prinz
  • Publication number: 20180178487
    Abstract: A plank is described and a method for manufacturing the plank. The plank can be produced by mixing polyvinyl chloride powder, coarse whiting and light calcium compound powder, stabilizer, polyethylene wax, internal lubricant, plasticizer, and impact modifier together, and stirring this mixture. The mixture is then extruded through an extruder compound to form a plastic composite base material. A surface layer is then tiled onto the plastic composite base material using thermal compression, without the use of intermediate adhesive materials. The surface layer can be embossed when it is combined with the mixture being extruded.
    Type: Application
    Filed: November 17, 2016
    Publication date: June 28, 2018
    Inventors: Ming Chen, Zhu Chen
  • Publication number: 20170355780
    Abstract: Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
    Type: Application
    Filed: June 12, 2017
    Publication date: December 14, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Zhu Chen, Kenneth Ellsworth, James Milligan, Elizabeth Oldham, Dietmar Seiffert, Vaishnavi Ganti, Mohammad Tabrizifard
  • Publication number: 20170321435
    Abstract: An engineered plank material and a method for making the plank material are disclosed. The plank material includes a veneer that is made out of plant material, and includes a nonwoven fabric or fiberglass mesh adhered to an inward-facing portion of the veneer. The plank material includes an adhesive paper material including macromolecular glue, which is between the veneer and a third layer of the plank material, which is constructed from one of bamboo, wood, or paper. The plank material then includes a fourth layer which is an adhesive paper material including a micromolecular glue. These layers are compressed together at a high heat and a high pressure in order to form the plank material.
    Type: Application
    Filed: May 4, 2016
    Publication date: November 9, 2017
    Inventors: Ming Chen, Zhu Chen
  • Publication number: 20170246845
    Abstract: A plank is described and a method for manufacturing the plank. The plank can be produced by mixing polyvinyl chloride powder, coarse whiting and light calcium compound powder, stabilizer, polyethylene wax, internal lubricant, plasticizer, and impact modifier together, and stirring this mixture. The mixture is then extruded through an extruder compound to form a plastic composite base material. A surface layer is then tiled onto the plastic composite base material using thermal compression, without the use of intermediate adhesive materials. The surface layer can be embossed when it is combined with the mixture being extruded.
    Type: Application
    Filed: May 16, 2017
    Publication date: August 31, 2017
    Inventors: Ming Chen, Zhu Chen
  • Publication number: 20170226225
    Abstract: Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.
    Type: Application
    Filed: January 19, 2017
    Publication date: August 10, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Zhu Chen, Kenneth P. Ellsworth, James A. Milligan, Elizabeth Oldham, Dietmar Seiffert, Vaishnavi Ganti, Mohammad Tabrizifard
  • Patent number: 9663013
    Abstract: This disclosure relates to a frame and a frame thereof. The frame comprises a frame body, wherein the frame further comprises an assistant unloading device disposed on the frame body, the assistant unloading device comprises an air bag, a mounting plate, and at least a set of guides; the air bag is fixed to the mounting plate, the guides comprises a guiding tube and a guiding rod, the guiding tube is vertically disposed on the frame body, the guiding rod is inserted into the guiding tube and connected to the mounting plate, and by inflating the air bag, the guiding rod is moved to vertically rise along the guiding tube to perform assistant unloading, thereby the trailer and frame of the disclosure have not only a simple structure, a light mass, and a lower cost, but also an excellent lifting capability and a stable lifting process.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: May 30, 2017
    Assignees: Shenzhen CIMC Vehicle Co., Ltd., CIMC Vehicles Group Co., Ltd., China International Marine Containers (Group) Ltd.
    Inventors: Peng Chen, Nan Li, Qingyuan Qin, Jianxing Wang, Zhuoan Wu, Xing Yan, Zhongcheng Gou, Zhu Chen, Ping Wang
  • Publication number: 20170138062
    Abstract: A floor fastener is described, including a main body configured to be removably attached to a surface. The floor fastener also includes one or more circlips, each of the one or more circlips fixed to the main body, each of the one or more circlips including a raised surface extending outward from the circlip and configured to removably attach to a flooring plank.
    Type: Application
    Filed: January 18, 2016
    Publication date: May 18, 2017
    Inventors: Ming Chen, Zhu Chen
  • Publication number: 20170136674
    Abstract: A plank is described and a method for manufacturing the plank. The plank can be produced by mixing polyvinyl chloride powder, coarse whiting and light calcium compound powder, stabilizer, polyethylene wax, internal lubricant, plasticizer, and impact modifier together, and stirring this mixture. The mixture is then extruded through an extruder compound to form a plastic composite base material. A surface layer is then tiled onto the plastic composite base material using thermal compression, without the use of intermediate adhesive materials.
    Type: Application
    Filed: January 18, 2016
    Publication date: May 18, 2017
    Inventors: Ming Chen, Zhu Chen
  • Publication number: 20170136735
    Abstract: A plank is described and a method for manufacturing the plank. The plank can be produced by mixing polyvinyl chloride powder, coarse whiting and light calcium compound powder, stabilizer, polyethylene wax, internal lubricant, plasticizer, and impact modifier together, and stirring this mixture. The mixture is then extruded through an extruder compound to form a plastic composite base material. A surface layer is then tiled onto the plastic composite base material using thermal compression, without the use of intermediate adhesive materials.
    Type: Application
    Filed: May 3, 2016
    Publication date: May 18, 2017
    Inventors: Ming Chen, Zhu Chen
  • Patent number: 9590253
    Abstract: The present invention relates to a bifunctional catalyst for use with air metal batteries and fuel cell. The bifunctional catalyst comprising a core and a shell, where the core comprises a metal oxide and the shell comprises a carbon nanostructure. In a further aspect the bifunctional catalyst is catalytically active for oxygen reduction and oxygen evolution reactions.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: March 7, 2017
    Inventors: Zhongwei Chen, Zhu Chen
  • Publication number: 20160185269
    Abstract: This disclosure relates to a frame and a frame thereof. The frame comprises a frame body, wherein the frame further comprises an assistant unloading device disposed on the frame body, the assistant unloading device comprises an air bag, a mounting plate, and at least a set of guides; the air bag is fixed to the mounting plate, the guides comprises a guiding tube and a guiding rod, the guiding tube is vertically disposed on the frame body, the guiding rod is inserted into the guiding tube and connected to the mounting plate, and by inflating the air bag, the guiding rod is moved to vertically rise along the guiding tube to perform assistant unloading, thereby the trailer and frame of the disclosure have not only a simple structure, a light mass, and a lower cost, but also an excellent lifting capability and a stable lifting process.
    Type: Application
    Filed: December 30, 2015
    Publication date: June 30, 2016
    Applicants: Shenzhen CIMC Vehicle Co., Ltd., CIMC Vehicles Group Co., Ltd., China International Marine Containers (Group) Ltd.
    Inventors: Peng Chen, Nan Li, Qingyuan Qin, Jianxing Wang, Zhuoan Wu, Xing Yan, Zhongcheng Gou, Zhu Chen, Ping Wang
  • Publication number: 20140229133
    Abstract: Parameters of a three phase mixture of sinusoids with harmonic distortion are estimated by first acquiring samples of the signal for no more than a quarter cycle of the signal, a classifier is applied to the samples to obtain noise and signal parameters. Then, initial parameters are estimated to obtain final parameters.
    Type: Application
    Filed: February 12, 2013
    Publication date: August 14, 2014
    Applicant: MITSUBISHI ELECTRIC RESEARCH LABORATORIES, INC.
    Inventors: Zafer Sahinoglu, Zhu Chen