Abstract: The present invention discloses an optimization method for joint scheduling of manned buses and autonomous buses, which fully considers the possibility of improving bus service quality and reducing operating costs using the variable capacity characteristics of autonomous buses. For passengers, the optimization method for joint scheduling dynamically adjusts the capacity and departure frequency of autonomous buses according to passenger demands, shortens passenger waiting time, and lowers the risk that a passenger cannot get on a bus during the peak period; and for bus management departments, the optimization method for joint scheduling ensures full utilization of manned buses and autonomous buses, improves scheduling efficiency, and saves operating costs by dynamically adjusting the capacity of autonomous buses during the peak period and flat peak period.