Patents by Inventor Zhuanyou Zhao

Zhuanyou Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition comprising candesartan or ester thereof and chlortalidone, and use thereof
    Patent number: 9216169
    Abstract: Provided is a pharmaceutical composition comprising candesartan or ester thereof and chlorthalidone, and use thereof, wherein the weight ratio of candesartan or ester thereof to chlorthalidone is 5.3:1 to 1:6.25. The pharmaceutical composition has a synergistic antihypertensive effect, and can enhance the antihypertensive effect and extend duration of antihypertension.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: December 22, 2015
    Assignee: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH
    Inventors: Lida Tang, Zhuanyou Zhao, Weiting Wang, Wengong Xi, Chunhua Hao, Xiangwei Xu, Bing Yu
  • PHARMACEUTICAL COMPOSITION COMPRISING CANDESARTAN OR ESTER THEREOF AND CHLORTALIDONE, AND USE THEREOF
    Publication number: 20150011598
    Abstract: Provided is a pharmaceutical composition comprising candesartan or ester thereof and chlorthalidone, and use thereof, wherein the weight ratio of candesartan or ester thereof to chlorthalidone is 5.3:1 to 1:6.25. The pharmaceutical composition has a synergistic antihypertensive effect, and can enhance the antihypertensive effect and extend duration of antihypertension.
    Type: Application
    Filed: December 21, 2012
    Publication date: January 8, 2015
    Inventors: Lida Tang, Zhuanyou Zhao, Weiting Wang, Wengong Xi, Chunhua Hao, Xiangwei Xu, Bing Yu
  • Cycloastragenol monoglucoside, preparation, pharmaceutical composition and application thereof
    Patent number: 8835134
    Abstract: This invention provides a method for preparing cycloastragenol monoglucoside CMG (cycloastragenol-6-O-?-D-glucoside), comprising the steps of: a. using astragaloside IV or Astragali extracts prepared by a conventional method as raw materials and adding an appropriate solvent thereinto to form a raw material solution; b. adding hydrolase and allowing for hydrolysis at a constant temperature to obtain a hydrolysate; c. separating the hydrolysate with macroporous adsorption resin; and d. obtaining the product by purification and separation. The present invention further provides cycloastragenol-6-O-?-D-glucoside prepared according to the method of this invention as well as its use in the preparation of a medicament for treating cardiovascular diseases and pharmaceutical compositions comprising the same.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: September 16, 2014
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Yingmei Han, Guangping Xia, Weiren Xu, Zhuanyou Zhao, Wulin Liu, Naxia Zhao, Peng Liu, Shijun Zhang, Xiaoli Fu, Yuli Wang, Weiting Wang, Lida Tang
  • CYCLOASTRAGENOL MONOGLUCOSIDE, PREPARATION, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF
    Publication number: 20110218161
    Abstract: This invention provides a method for preparing cycloastragenol monoglucoside CMG (cycloastragenol-6-O-?-D-glucoside), comprising the steps of: a. using astragaloside IV or Astragali extracts prepared by a conventional method as raw materials and adding an appropriate solvent thereinto to form a raw material solution; b. adding hydrolase and allowing for hydrolysis at a constant temperature to obtain a hydrolysate; c. separating the hydrolysate with macroporous adsorption resin; and d. obtaining the product by purification and separation. The present invention further provides cycloastragenol-6-O-?-D-glucoside prepared according to the method of this invention as well as its use in the preparation of a medicament for treating cardiovascular diseases and pharmaceutical compositions comprising the same.
    Type: Application
    Filed: September 8, 2008
    Publication date: September 8, 2011
    Applicant: Tianjin Institute of Pharmaceutical Research
    Inventors: Yingmei Han, Guangping Xia, Weiren Xu, Zhuanyou Zhao, Wulin Liu, Naxia Zhao, Peng Liu, Shijun Zhang, Xiaoli Fu, Yuli Wang, Weiting Wang, Lida Tang