Patents by Inventor Zhuo HUANG

Zhuo HUANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AS BCL-2 INHIBITORS
    Publication number: 20250122191
    Abstract: Provided are certain BCL-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 10, 2022
    Publication date: April 17, 2025
    Inventors: Hongbin LIU, Hua XU, Weipeng ZHANG, Rui TAN, Jinhua YU, Yunling WANG, Yangli QI, Yue RONG, Zhuo HUANG, Ling CHEN, Chenglin ZHOU, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Modified Cell, And Preparation Method Therefor and Use Thereof
    Publication number: 20240424021
    Abstract: A modified cell, a method for preparing a modified cell, and a use thereof in treatment of a disease. The modified cell comprises a polynucleotide that encodes a presenting peptide, wherein the polynucleotide is under the transcriptional regulation of an endogenous B2M gene.
    Type: Application
    Filed: August 11, 2022
    Publication date: December 26, 2024
    Applicant: Cure Genetics Co., Ltd.
    Inventors: Zhuo HUANG, Yanni LIN, Xiaocui Zheng
  • GENETICALLY ENGINEERED CELLS AND USES THEREOF
    Publication number: 20240383962
    Abstract: Disclosed herein are fusion proteins having a ?2M polypeptide and a presenting peptide, and nucleic acids that encode such fusion proteins. Provided herein are also genetically engineered cells expressing such fusion protein, methods of their production, and their uses in allogeneic transplant. CAR-T cells expressing fusion protein disclosed herein and their uses in cancer treatment are also disclosed.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 21, 2024
    Inventors: Zhuo Huang, Yanni Lin, Xiaocui Zheng, Hongmei Kong, Wenbo Wang, Aihua Feng
  • METHOD FOR CONTROLLING OUTRIGGER OF PUMP TRUCK, PUMP TRUCK AND METHOD FOR CONTROLLING PUMP TRUCK
    Publication number: 20240368906
    Abstract: Disclosed are a method for controlling an outrigger of a pump truck, a method for controlling the pump truck and the pump truck. The method for controlling the outrigger of the pump truck of the present disclosure includes: obtaining a first tilting angle of an entire pump truck after a boom is unfolded; and in a case that the first tilting angle is larger than or equal to a first preset value, obtaining a current error count, and controlling the outrigger to act based on the current error count.
    Type: Application
    Filed: July 12, 2024
    Publication date: November 7, 2024
    Applicant: SANY AUTOMOBILE MANUFACTURING CO., LTD.
    Inventors: Tingting TANG, Zhuo HUANG, Wei LIU
  • PROLIFERATION ENHANCER AND USE THEREOF
    Publication number: 20240117007
    Abstract: The present invention relates to a proliferation enhancer. The enhancer comprises a protein molecule capable of initiating the cellular STATS and/or STAT3 signaling pathway and comprising the intracellular domain, the transmembrane domain and the extracellular domain. The present invention further relates to a lymphocyte expressing the proliferation enhancer and the use thereof as an immunotherapy drug.
    Type: Application
    Filed: February 10, 2022
    Publication date: April 11, 2024
    Inventors: Zhuo HUANG, Yanni Lin, Xun ZHAO, Xiaocui ZHENG