Abstract: A long-life sealing structure of a membrane electrode for fuel cells includes an anode plate and a cathode plate, which are stacked together and sandwich a proton exchange membrane and two diffusion sheets between them. Both ends of the anode plate and the cathode plate are provided with through-holes. The outer surface of the anode plate is provided with a sealing groove assembly including a first ring groove, a strip groove and a second annular groove. The first ring groove is embedded with a sealing ring. The interior of the strip groove is stepped, with guide grooves on both sides extending outward to the surface of the anode plate; the strip groove is embedded with a sealing strip with its outer surface fitted with a cover. The adsorption-type sealing mechanism provides targeted sealing for the connection between the membrane electrode and the catalytic sheet, enhances the sealing performance.