Patents by Inventor Zhuyin Li

Zhuyin Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Identifying and Treating Dystonia Disorders
    Publication number: 20220313680
    Abstract: The present disclosure provides methods and compositions for the treatment, identification, diagnosis, and prognosis of dystonia, or dystonia related disorders.
    Type: Application
    Filed: March 28, 2022
    Publication date: October 6, 2022
    Inventors: Nicole Calakos, Zachary F. Caffall, Joseph Rittiner, Min Shen, Jennifer T. Fox, Zhuyin Li
  • Compositions and methods for identifying and treating dystonia disorders
    Patent number: 11285142
    Abstract: The present disclosure provides methods and compositions for the treatment, identification, diagnosis, and prognosis of dystonia, or dystonia related disorders.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: March 29, 2022
    Assignees: The United States of America, as Represented by the Secretary, Department of Health and Human Services, Duke University
    Inventors: Nicole Calakos, Zachary F. Caffall, Joseph Rittiner, Min Shen, Jennifer T. Fox, Zhuyin Li
  • Compositions and Methods for Identifying and Treating Dystonia Disorders
    Publication number: 20180271929
    Abstract: The present disclosure provides methods and compositions for the treatment, identification, diagnosis, and prognosis of dystonia, or dystonia related disorders.
    Type: Application
    Filed: September 29, 2016
    Publication date: September 27, 2018
    Inventors: Nicole Calakos, Zachary F. Caffall, Joseph Rittiner, Min Shen, Jennifer T. Fox, Zhuyin Li
  • DNA FRAGMENTATION ASSAY
    Publication number: 20100248224
    Abstract: The present invention provides methods for the detection of agents that modify the formation of DNA fragmentation in cells. The disclosed methods are configured in an assay format amendable to high throughput screening applications.
    Type: Application
    Filed: June 20, 2007
    Publication date: September 30, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Tina Garyantes, Zhuyin Li, Yongping Yan, Justin Anthony Yu, Asher Zilberstein
  • ASSAY METHODS FOR IDENTIFYING AGENTS THAT MODIFY THE ACTIVITY OF NAPE-PLD OR Abh4
    Publication number: 20100143937
    Abstract: The present invention provides methods for the detection of agents that modify the activity of the N-acylphosphatidylethanolamine-hydrolysing phospholipase D (NAPE-PLD) enzyme or the Alpha/beta-hydrolase-4 (Abh4) enzyme. The disclosed methods are configured in an assay format amenable to high throughput screening applications.
    Type: Application
    Filed: May 29, 2008
    Publication date: June 10, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Jane Vivienne Peppard, Shujaath Mehdi, Zhuyin Li, Mei S. Duguid
  • Method for assaying compounds or agents for ability to decrease the activity of microsomal prostaglandin E synthase or hematopoietic prostaglandin D synthase
    Publication number: 20040082021
    Abstract: Provided herein is a novel and useful method for evaluating the ability of compounds or agents to decrease the activity of microsomal prostaglandin E synthase or hematopoietic prostaglandin D synthase to produce their respective prostaglandin products.
    Type: Application
    Filed: August 15, 2003
    Publication date: April 29, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Zhuyin Li, Junjie Xiong, Henry Ma, Jeffrey S. Sabol
  • Immunoassay based on DNA replication using labeled primer
    Publication number: 20020072053
    Abstract: An immunoassay method based upon inhibition of a DNA polymerase enzyme accomplished by linking a ligand of the analyte to a primer through a covalent bond. The interaction between the primer-bound ligand and a receptor specific for the ligand inhibits the DNA polymerase enzyme from generating double stranded DNA. The degree of inhibition of double stranded DNA synthesis is inversely proportional to the concentration of analyte in the sample. The analyte is determined by measuring the formation of double stranded DNA, e.g., by a fluorescence DNA intercalation technique.
    Type: Application
    Filed: December 8, 2000
    Publication date: June 13, 2002
    Inventors: Alan J. McNally, Robert S. Wu, Zhuyin Li