Patents by Inventor Zhuying Wang

Zhuying Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12012595
    Abstract: An improved peptide library preparation method is described for constructing complete peptide libraries such as a complete tripeptide library, tetrapeptide library, pentapeptide library, hexapeptide library, heptapeptide library, or a complete octapeptide library, etc. The method includes constructing an expression vector for the expression of tagged peptides. Each tagged peptide contains an array of peptides of different sizes, and the number of peptides in a complete peptide library can be dramatically reduced relative to conventional chemical peptide synthesis. Furthermore, the libraries can be readily reproduced. The improved peptide library preparation method can particularly be used, for example, to construct a complete pentapeptide library. Other related methods and related expression vectors are also described.
    Type: Grant
    Filed: July 3, 2015
    Date of Patent: June 18, 2024
    Assignee: HUNAN ZONSEN PEPLIB BIOTECH CO., LTD
    Inventors: Zhuying Wang, Xiangqun Li
  • Publication number: 20240193064
    Abstract: Methods and devices for monitoring and maintaining a health state of an electrical device. The methods can include obtaining a first operation state of the electrical device; rendering a holographic image of the electrical device and a first health state of the electrical device indicated by the first operation state by using a mixed reality device; detecting an action of a first user by using the mixed reality device; in response to that an operation performed by the first user on the electrical device has been detected, performing the operation on an image model of the electrical device in the holographic image to obtain a second operation state after the electrical device is operated; and updating the first health state to a second health state indicated by the second operation state.
    Type: Application
    Filed: November 30, 2023
    Publication date: June 13, 2024
    Inventors: Wei Zheng, Zhui Wang, Longbin Huang, Zhen Chen, Changhui You
  • Patent number: 11978533
    Abstract: An improved peptide library preparation method is described for constructing complete virtual peptide libraries such as a complete virtual tripeptide library, tetrapeptide library, pentapeptide library, hexapeptide library, heptapeptide library, or a complete octapeptide library, etc. The method includes constructing an expression vector for the expression of cyclic peptides. Each cyclic peptide displays an array of peptides of different sizes and sequences, and the number of cyclic peptides needed for constructing a complete virtual peptide library can be dramatically reduced compared with conventional chemical peptide synthesis. Furthermore, the cyclic peptide libraries can be readily reproduced by the expression and purification of the cyclic peptides using the constructed gene libraries.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: May 7, 2024
    Assignee: HUNAN ZONSEN PEPLIB BIOTECH CO., LTD
    Inventors: Zhuying Wang, Xiangqun Li
  • Patent number: 11615189
    Abstract: In some embodiments, there is provided a method for updating a gateway in a substation. The method includes receiving, at a gateway from a server, an update package assigned with a first identifier, the update package including at least one of: a configuration associated with at least one monitoring device connected to the gateway; and an application configurable to collect data from the at least one monitoring device; in response to receiving the update package, determining whether the first identifier matches a second identifier of the gateway; and in response to determining that the first identifier matches the second identifier of the gateway, updating the gateway with the received update package.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: March 28, 2023
    Assignee: ABB SCHWEIZ AG
    Inventors: Huixiang Chen, Zhui Wang, Hongzheng Chen
  • Patent number: 11477051
    Abstract: Embodiments of the present disclosure relate to a data transmission method and associated devices. In the method, data collected by at least one monitoring device in a substation is received at a gateway. Further, a status of a connection between the gateway and a first network is detected, where the first network enables communication between the gateway and a server. Further, in response to detecting a disconnection between the gateway and the first network, the data is sent to a user device via a second network hosted by the gateway to enable the user device to forward the data to the server.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: October 18, 2022
    Assignee: ABB SCHWEIZ AG
    Inventors: Zhui Wang, Huixiang Chen, Hongzheng Chen
  • Publication number: 20210214788
    Abstract: The disclosure relates to an improved method for detecting, locating and monitoring fluid seepage and leakage from a hydraulic work with superior sensitivity. The method includes using a DNA sequence as the probe to trace the fluid seepage and leakage from a hydraulic work. The probe can be captured and then amplified more than a millionfold by an enzymatic method such as the polymerase chain reaction (PCR) to give a high detection signal. Even a single molecule of the DNA probe can be detected by an enzymatic amplification, thus to give superior sensitivity. The improved detection method is applicable to detecting, locating and monitoring fluid seepage and leakage from hydraulic works, the improved method can also be used, for example, to trace the groundwater flow, underground water flow and other liquid flow. Other related methods are also described.
    Type: Application
    Filed: January 26, 2016
    Publication date: July 15, 2021
    Inventors: Zhuying WANG, Mingxia SHEN, Linhua JIANG
  • Publication number: 20200293660
    Abstract: In some embodiments, there is provided a method for updating a gateway in a substation. The method includes receiving, at a gateway from a server, an update package assigned with a first identifier, the update package including at least one of: a configuration associated with at least one monitoring device connected to the gateway; and an application configurable to collect data from the at least one monitoring device; in response to receiving the update package, determining whether the first identifier matches a second identifier of the gateway; and in response to determining that the first identifier matches the second identifier of the gateway, updating the gateway with the received update package.
    Type: Application
    Filed: May 28, 2020
    Publication date: September 17, 2020
    Inventors: Huixiang Chen, Zhui Wang, Hongzheng Chen
  • Publication number: 20200295971
    Abstract: Embodiments of the present disclosure relate to a data transmission method and associated devices. In the method, data collected by at least one monitoring device in a substation is received at a gateway. Further, a status of a connection between the gateway and a first network is detected, where the first network enables communication between the gateway and a server. Further, in response to detecting a disconnection between the gateway and the first network, the data is sent to a user device via a second network hosted by the gateway to enable the user device to forward the data to the server.
    Type: Application
    Filed: May 28, 2020
    Publication date: September 17, 2020
    Inventors: Zhui Wang, Huixiang CHEN, Hongzheng CHEN
  • Publication number: 20200135299
    Abstract: An improved peptide library preparation method is described for constructing complete virtual peptide libraries such as a complete virtual tripeptide library, tetrapeptide library, pentapeptide library, hexapeptide library, heptapeptide library, or a complete octapeptide library, etc. The method includes constructing an expression vector for the expression of cyclic peptides. Each cyclic peptide displays an array of peptides of different sizes and sequences, and the number of cyclic peptides needed for constructing a complete virtual peptide library can be dramatically reduced compared with conventional chemical peptide synthesis. Furthermore, the cyclic peptide libraries can be readily reproduced by the expression and purification of the cyclic peptides using the constructed gene libraries.
    Type: Application
    Filed: April 26, 2017
    Publication date: April 30, 2020
    Inventors: Zhuying Wang, Xiangqun Li
  • Publication number: 20180179519
    Abstract: An improved peptide library preparation method is described for constructing complete peptide libraries such as a complete tripeptide library, tetrapeptide library, pentapeptide library, hexapeptide library, heptapeptide library, or a complete octapeptide library, etc. The method includes constructing an expression vector for the expression of tagged peptides. Each tagged peptide contains an array of peptides of different sizes, and the number of peptides in a complete peptide library can be dramatically reduced relative to conventional chemical peptide synthesis. Furthermore, the libraries can be readily reproduced. The improved peptide library preparation method can particularly be used, for example, to construct a complete pentapeptide library. Other related methods and related expression vectors are also described.
    Type: Application
    Filed: July 3, 2015
    Publication date: June 28, 2018
    Inventors: Zhuying Wang, Xiangqun LI
  • Patent number: 9061236
    Abstract: A device for gel electrophoresis is provided having larger wells for loading an increased sample volume with improved gel resolution. The device includes a gel cassette having a front plate and a back plate, wherein at least one plate has a stepped inner surface to create a wider opening at the top of the gel cassette, a gel matrix, and a comb with teeth having a thickness substantially equal to the spacing at the top opening of the gel cassette. Using this device, the sample volume in each well can be increased and the sample height in each well can be significantly reduced, as compared to loading the same volume in the wells of a standard gel cassette.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: June 23, 2015
    Assignee: Nanjingjinsirui Science & Technology Biology Corporation
    Inventors: Zhuying Wang, Hong Qian, Yuanming Liao, Tao Bai
  • Patent number: 8968541
    Abstract: An improved staining method is described for staining a biopolymer such as a peptide, a protein, an RNA, a DNA, an oligosaccharide or a complex containing a peptide, a protein, an RNA, a DNA, or an oligosaccharide in a matrix. The method includes the step of moving a staining reagent into the matrix using an electric force. The staining time can be dramatically reduced relative to conventional technologies. The improved staining method can particularly be used, for example, to stain proteins after gel separation. Other related methods and related kits are also described.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: March 3, 2015
    Assignee: Nanjingjinsirui Science & Technology Biology Corp.
    Inventors: Zhuying Wang, Jinyu Yang, Fanli Meng, Bing Lai, Zhan Dai, Fang Liang Zhang
  • Publication number: 20140241510
    Abstract: A remote controller, a remote control system and an X-ray system including the same. The remote control system includes a remote controller and a processing unit located in a controlled system controlled by the remote controller. The remote controller includes at least one key for a user to select a controlled object to be controlled via the remote controller, a sensing unit for sensing an orientation of the remote controller; and a wireless transmitter for transmitting to the controlled system which of the at least one key is selected by the user and orientation information of the remote controller sensed by the sensing unit. The processing unit generates a control command for the controlled system in accordance with information about the user's key selection and orientation information of the remote controller to control movement of a controlled object corresponding to the selected key in accordance with the remote control's orientation.
    Type: Application
    Filed: February 28, 2014
    Publication date: August 28, 2014
    Applicant: GE Medical Systems Global Technology Company, LLC
    Inventors: Zhuying WANG, Yingjie JIA
  • Patent number: 8815600
    Abstract: Methods and compositions for cloning a donor DNA molecule into an acceptor vector at a predetermined location are described. The methods are based on homologous recombination mediated by in vitro treatment of the donor DNA and the acceptor vector with an enzyme cocktail containing an exonuclease and a single-stranded DNA binding protein.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: August 26, 2014
    Assignee: GenScript Hongkong
    Inventors: Weiqiang Liu, Ping Yang, Tao Wang, Zhuying Wang, Wenzhu Chen, Fang Liang Zhang
  • Patent number: 8785352
    Abstract: Provided, among other things, is a multiplex assay comprising: conducting a fluorescence-developing assay on microtabs having at least one surface that shows plasmonic enhancement, wherein a plurality of the microtabs have unique probes affixed to their plasmonically enhanced surfaces; and measuring the fluorescence associated with the substrates and identifying the correlated probe by for the microtab. The microtabs can be, for example, MTPs that send a unique identifier, and the correlated probe can be identified by querying the MTPs for their identifier.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: July 22, 2014
    Assignee: Pharmaseq, Inc.
    Inventors: Wlodek Mandecki, Ji Li, Zhuying Wang
  • Publication number: 20140138249
    Abstract: A device for gel electrophoresis is provided having larger wells for loading an increased sample volume with improved gel resolution. The device includes a gel cassette having a front plate and a back plate, wherein at least one plate has a stepped inner surface to create a wider opening at the top of the gel cassette, a gel matrix, and a comb with teeth having a thickness substantially equal to the spacing at the top opening of the gel cassette. Using this device, the sample volume in each well can be increased and the sample height in each well can be significantly reduced, as compared to loading the same volume in the wells of a standard gel cassette.
    Type: Application
    Filed: November 20, 2012
    Publication date: May 22, 2014
    Applicant: Nanjingjinsirui Science & Technology Biology Corporation
    Inventors: Zhuying WANG, Hong QIAN, Yuanming LIAO, Tao BAI
  • Patent number: 8603780
    Abstract: Optimized signal peptide coding sequences for enhanced expression and secretion of protein from a cell and related compositions and methods are described. The optimized signal peptide coding sequence encodes an mRNA that contains at least one hairpin structure immediately downstream of the initiation codon. Methods for obtaining the optimized signal peptide coding sequences and methods for enhanced expression and secretion of proteins using the optimized signal peptide coding sequences are also described.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: December 10, 2013
    Assignee: Nanjingjinsirui Science & Technology Biology Corp.
    Inventors: Zhuying Wang, Xiaowu Liu
  • Patent number: 8501454
    Abstract: Methods and compositions for cloning a donor DNA molecule into an acceptor vector at a predetermined location are described. The methods are based on homologous recombination mediated by in vitro treatment of the donor DNA and the acceptor vector with an enzyme cocktail containing an exonuclease and a single-stranded DNA binding protein.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: August 6, 2013
    Assignee: Nanjingjinsirui Science & Technology Biology Corp.
    Inventors: Weiqiang Liu, Ping Yang, Tao Wang, Zhuying Wang, Wenzhu Chen, Fang Liang Zhang
  • Publication number: 20130123118
    Abstract: Provided, among other things, is a multiplex assay comprising: conducting a fluorescence-developing assay on microtabs having at least one surface that shows plasmonic enhancement, wherein a plurality of the microtabs have unique probes affixed to their plasmonically enhanced surfaces; and measuring the fluorescence associated with the substrates and identifying the correlated probe by for the microtab. The microtabs can be, for example, MTPs that send a unique identifier, and the correlated probe can be identified by querying the MTPs for their identifier.
    Type: Application
    Filed: April 29, 2011
    Publication date: May 16, 2013
    Applicant: PharmaSeq, Inc.
    Inventors: Wlodek Mandecki, Ji Li, Zhuying Wang
  • Publication number: 20130017574
    Abstract: Optimized signal peptide coding sequences for enhanced expression and secretion of protein from a cell and related compositions and methods are described. The optimized signal peptide coding sequence encodes an mRNA that contains at least one hairpin structure immediately downstream of the initiation codon. Methods for obtaining the optimized signal peptide coding sequences and methods for enhanced expression and secretion of proteins using the optimized signal peptide coding sequences are also described.
    Type: Application
    Filed: July 16, 2012
    Publication date: January 17, 2013
    Applicant: NANJINGJINSIRUI SCIENCE & TECHNOLOGY BIOLOGY CORP.
    Inventors: Zhuying WANG, Xiaowu LIU