Patents by Inventor Zhuying ZHANG

Zhuying ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Catechol group modified biomacromolecular scaffold material and preparation method thereof
    Patent number: 11384162
    Abstract: The invention discloses a preparation method of a catechol group modified biomacromolecular scaffold material, comprising: grafting a catechol-containing compound by amidation to obtain modified biomacromolecules; then, allowing dopamine to perform oxidized self-polymerization in a weakly alkaline buffer solution to form polydopamine (PDA) particles with a uniform particle size; next, forming a scaffold which has three cross-linking structures, namely modified biomacromolecules, modified biomacromolecules/PDA, and biomacromolecules/PDA, through interaction between catechol groups, interaction between catechol groups and PDA particles, and interaction between macromolecules and PDA particles in the modified macromolecules respectively; and cross-linking the scaffold with calcium ions, adipic dihydrazide or genipin to further adjust the degree of cross-linking and porosity of the scaffold.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: July 12, 2022
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Dongjian Shi, Jiali Shen, Zhuying Zhang, Chuanhao Cao, Qian Zhao, Xiaojie Li, Mingqing Chen
  • CATECHOL GROUP MODIFIED BIOMACROMOLECULAR SCAFFOLD MATERIAL AND PREPARATION METHOD THEREOF
    Publication number: 20190062462
    Abstract: The invention discloses a preparation method of a catechol group modified biomacromolecular scaffold material, comprising: grafting a catechol-containing compound by amidation to obtain modified biomacromolecules; then, allowing dopamine to perform oxidized self-polymerization in a weakly alkaline buffer solution to form polydopamine (PDA) particles with a uniform particle size; next, forming a scaffold which has three cross-linking structures, namely modified biomacromolecules, modified biomacromolecules/PDA, and biomacromolecules/PDA, through interaction between catechol groups, interaction between catechol groups and PDA particles, and interaction between macromolecules and PDA particles in the modified macromolecules respectively; and cross-linking the scaffold with calcium ions, adipic dihydrazide or genipin to further adjust the degree of cross-linking and porosity of the scaffold.
    Type: Application
    Filed: August 31, 2017
    Publication date: February 28, 2019
    Inventors: Dongjian SHI, Jiali SHEN, Zhuying ZHANG, Chuanhao CAO, Qian ZHAO, Xiaojie LI, Mingqing CHEN