Abstract: An ophthalmic device can be positioned on a surface of an eye and can modulate an amount of light that can be transmitted therethrough in response to environmental factors and/or release of a therapeutic agent into the eye. The ophthalmic device can include an electronically-mediated medium that can modulate an amount of light transmitted in response to a first electrical signal generated by a signal generator. The ophthalmic device also can include at least one drug reservoir that can release a therapeutic agent to the eye in response to a second electrical signal generated by the signal generator. The signal generator can be encapsulated within the ophthalmic device and in communication with a controller that defines parameters of the electrical signals generated by the signal generator.

Abstract: A wearable device can include a sweat collection unit, and optionally, a sweat stimulation unit. The sweat collection unit includes at least one microfluidics channel to collect sweat from a user, a chamber to hold the sweat, and a loading chamber with sweat collection paper that attracts the sweat through the chamber. A chloride sensing unit located within the chamber includes a gold working electrode and a counter electrode that can determine if enough sweat is in the chamber and, if enough, the chloride concentration of the sweat can be determined based on electrochemical reactions in response to electrical signals applied through the electrodes. A controller of the device can notify a user to trigger the sweat stimulation unit if not enough sweat is in the chamber.

Abstract: The present disclosure relates to non-destructive methods for collecting data from three-dimensional objects. Method include directing one or more interrogating beams of light towards a surface of a three-dimensional object, where the three-dimensional object includes one or more underlying surfaces, and one or more materials having excitonic properties are disposed on the surface of the three-dimensional object; capturing, using an imaging device, optic response of the one or more materials having excitonic properties to the one or more interrogation beams; and computing, using the imaging device, a distance between the one or more underlying surfaces and the one or more materials having excitonic properties, where the optic response of the one or more materials having excitonic properties is a function of the distance between the one or more materials having excitonic properties and the one or more underlying surfaces.

Abstract: Efficient electrochemical reactions can be achieved using a two-electrode system embedded within a silicone hydrogel by using a one-step linear sweep-hold method. A voltage value is initially set to be a voltage that corresponds to a peak current (Vp). An amperometric process is performed at the voltage value. During the amperometric process, the voltage value is corrected as a current shifts.

Abstract: An ophthalmic device including a hydrogel-based material body that can encapsulate a reservoir housing a therapeutic and a metal electrode covering the reservoir. The therapeutic can be delivered into an eye by way of electrodissolution of the metal electrode. The electrodissolution can be enhanced by the presence of chloride ions proximal to the metal electrode, and the ophthalmic device can be engineered to ensure the presence of chloride ions proximal to the metal electrode.

Abstract: a substrate configured to be positioned in the presence of a fluid; a first electrode comprising a conductive film disposed on the substrate; and a second electrode comprising the conductive film disposed on the substrate and spaced from the first electrode. The device may further include a current measurement circuit configured to: apply a voltage between the first electrode and the second electrode, wherein the voltage is in an electrochemical active range of the conductive film such that a portion of the conductive film dissolves into the fluid; and transmit, to a processor, a signal indicating a current measurement of an electrical current flowing through the fluid including the dissolved portion of the conductive film.

Abstract: The present disclosure relates to non-destructive methods for collecting data from three-dimensional objects. Method include directing one or more interrogating beams of light towards a surface of a three-dimensional object, where the three-dimensional object includes one or more underlying surfaces, and one or more materials having excitonic properties are disposed on the surface of the three-dimensional object; capturing, using an imaging device, optic response of the one or more materials having excitonic properties to the one or more interrogation beams; and computing, using the imaging device, a distance between the one or more underlying surfaces and the one or more materials having excitonic properties, where the optic response of the one or more materials having excitonic properties is a function of the distance between the one or more materials having excitonic properties and the one or more underlying surfaces.