Abstract: Provided are a sequencing library and applications thereof. The provided sequencing library includes a first nucleic acid molecule and a second nucleic acid molecule. The first nucleic acid molecule carries a cell index sequence and a droplet index sequence. The second nucleic acid molecule carries an insert fragment and a cell index sequence.

Abstract: A technique is provided for detecting episodes of cardiac ischemia based on an examination of post-T-wave signal segments. Since cardiac ischemia is often a precursor to acute myocardial infarction (AMI) or ventricular fibrillation (VF), the technique thereby provides a method for predicting the possible onset of AMI or VF so that a warning may be delivered to the patient. The warning preferably includes both a perceptible electrical notification signal applied directly to subcutaneous tissue and a warning signal delivered via short range telemetry to a handheld warning device external to the patient. In one example, the onset of cardiac ischemia is identified by detecting a sharp falling edge within post-T-wave signals by filtering the signals using a high-pass filter having a cutoff frequency of at least 1 Hz. The total amount of energy in the filtered signal is calculated and compared against various thresholds.

Abstract: The present invention provides a processing apparatus and methods for the extraction of user information streams from a composite CDMA waveform. The apparatus and methods increase CDMA system capacity by orthogonalizing an individual user's signal from thermal noise components, multi-access interference, and spatially diverse but non-orthogonal coded components. The present invention exploits both the temporal diversity and the spatial diversity present in the received composite CDMA waveform to increase performance. The smart antenna multiuser detector makes use of blind-block-adaptive nonlinear optimization strategies, which are used to separate user signal components from a composite CDMA waveform by jointly processing in both a chip (code) and spatial domain.

Abstract: An apparatus and method for spread spectrum multiuser communication receivers is disclosed that includes, an adaptive filter adapted to minimize a block error function, wherein the filter tap weights are updated according to a non-linear optimization algorithm adapted for block processing of time-varying data.