Patents by Inventor Zigmunt Kasimierczuk

Zigmunt Kasimierczuk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-deoxy-isoguanosines isosteric analogues and isoguanosine derivatives as well as their synthesis
    Patent number: 6498241
    Abstract: 2′-Deoxyisoguanosine, isosteric analogues and isoguanosine derivatives of formulae I-V, processes for their production via compounds of the general formulae a or b and reaction with aroyl isocyanates or from compounds of the general formulae VI-IX by photochemical irradiation. A further production process is the conversion of deoxyguanosines or guanosines by means of persilylation, reaction with ammonia and deamination in the 2 position. The compounds are suitable as pharmaceutical agents with antiviral efficacy.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: December 24, 2002
    Assignee: Roche Diagnostics GmbH
    Inventors: Frank Seela, Zigmunt Kasimierczuk, Klaus Mühlegger, Herbert Von Der Eltz
  • 2-deoxy-isoguanosines isoteric analogues and isoguanosine containing oligonucleotides
    Patent number: 6147199
    Abstract: 2'-Deoxyisoguanosine, isosteric analogues and isoguanosine derivatives of formulae I-V, processes for their production via compounds of the general formulae a or b and reaction with aroyl isocyanates or from compounds of the general formulae VI-IX by photochemical irradiation. A further production process is the conversion of deoxyguanosines or guanosines by means of persilylation, reaction with ammonia and deamination in the 2 position. The compounds are suitable as pharmaceutical agents with antiviral efficacy.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: November 14, 2000
    Assignee: Boehringer Mannheim
    Inventors: Frank Seela, Zigmunt Kasimierczuk, Klaus Muhlegger, Herbert Von Der Eltz