Abstract: The invention relates to a double-microenvironment three-layer bionic hydrogel scaffold and a preparation method and application thereof, which are characterized in that includes a cartilage layer GL-HPKGN, an intermediate layer GL-GMA, and a bone layer GL-HP/GMAAT; by an enzymatic crosslinking reaction based on hydroxyphenylpropionic acid (HPA), kartogenin (KGN) is grafted onto gelatin to form a cartilage-specific microenvironment in GL-HPKGN; Based on hydroxyphenylpropionic acid (HPA), a dual crosslinking network was formed by enzyme crosslinking reaction and methacryloyl-glycidyl dimethicone (GMA) photo-crosslinking reaction, which was used to graft atorvastatin (AT) onto gelatin, forming GL-HP/GMAAT with bone-specific microenvironment; the intermediate layer GL-GMA was beneficial for forming a clear and defined cartilage-bone integrated structure. The introduction of the tide-line intermediate layer GL-GMA facilitated the formation of well-defined chondro-bone integrated structures.

Abstract: An apparatus for evaluating a dried crystal error in a CO2 drying experiment comprises a heating jacket, a visual container, a weighing device, a transparent cover, a control apparatus, a vacuum pump, a damping table and a heating apparatus, and can accurately dry and weigh a rock sample subjected to a carbon dioxide drying effect experiment in the visual container, so that the crystal error caused by evaporation of a solution in the rock sample in the process is calculated. This apparatus provided by the present invention has high precision and simple operation, can well evaluate the crystal error caused by the saline solution retaining in the rock sample when the rock sample is directly dried in the carbon dioxide drying effect experiment, and can correct the results of the carbon dioxide drying effect experiment compared with the prior art, thereby obtaining accurate experiment results.

Abstract: An intelligent identification method of aquifer distribution in complex edge-water oil and gas reservoirs is provided. The problem, that targeted water control countermeasures cannot be proposed due to unclear identification of edge-water distribution in complex edge-water reservoirs, is resolved. Based on geological data and production data of a single well, establish a numerical simulation model of a water influx unit for simulating inflow dynamic of complex edge-water influx; by a genetic algorithm, correct characteristic parameters of an aquifer unit, including volume and water influx of the aquifer unit; automatically fit dynamic production data calculated by the model with actual dynamic production data, to obtain optimal characteristic parameters of the aquifer unit; and assign the characteristic parameters to the aquifer unit for inversion to determine aquifer distribution.

Abstract: The present disclosure relates to a prediction method for constant production decline of a water-producing gas well in a highly heterogeneous reservoir.