Abstract: This disclosure provide a nanopillar electrode device, comprising a substrate patterned with a plurality of metal pads. The device may further comprise a plurality of nanopillars electrode arrays, wherein each nanopillar electrode array is attached to the substrate above a metal pad and electrically connected to the pad. The device may further comprise and a chamber surrounding the nanopillar electrodes, which can be used for culturing cells of interest for recording action potentials. The nanopillar electrode device may be configured to apply a voltage through the nanopillar electrodes from a voltage source. Nanopillar electroporation may be used to increase the permeability of cell membranes to allow intracellular recording. Also provided are methods of device fabrication, and methods of use.

Abstract: A reconnect restriction evaluator is described. After detecting that a certain number of the reconnect requests submitted by a member of an on-line social network have failed, the reconnect restriction evaluator performs additional evaluation of the history of reconnect requests stored as associated with a profile of the member and determines whether the high count of failed requests recorded against the member are offset by one or more offsetting factors. Based on the result of the additional evaluation, the reconnect restriction evaluator generates an exemption indicator and stores it as associated with the profile of the member.

Abstract: A phony profiles detector for an on-line social network system is described. The phony profiles detector uses characteristics of a profile that was associated with an indication that it represents a malicious user, a so-called seed profile, to identify other profiles that should be flagged as potentially the source of undesirable behavior. Based on the degree of similarity determined for a subject profile with respect to a seed profile, the phony profiles detector generates a malicious user indicator and stores it as associated with the subject profile.

Abstract: An Account Takeover (ATO) threat detection system is configured to detect that a group of IP addresses is a suspected group of IP addresses (in that there is an indication that same potentially malicious entity is using a group of IP addresses to attempt logins) and automatically select a lower value that limits how many login attempts from the same IP address are permitted during a predetermined period of time before a login request from the suspected group of IP address is no longer accepted for processing. The limit that is used to restrict login attempts from a single IP address is set to be lower than a solo threshold value.

Abstract: An Account Takeover (ATO) detection system is configured to generate a visualization of the monitored login attempts during a time period with respect to an on-line service. In the visualization, a login attempt from an IP address is presented as an object in a three-dimensional coordinates system. This three-dimensional coordinates system has the first axis representing the first octet of an IP address, the second axis representing the second octet of an IP address, and the third axis representing the third and the fourth octets of the IP address.

Abstract: This disclosure provide a nanopillar electrode device, comprising a substrate patterned with a plurality of metal pads. The device may further comprise a plurality of nanopillars electrode arrays, wherein each nanopillar electrode array is attached to the substrate above a metal pad and electrically connected to the pad. The device may further comprise and a chamber surrounding the nanopillar electrodes, which can be used for culturing cells of interest for recording action potentials. The nanopillar electrode device may be configured to apply a voltage through the nanopillar electrodes from a voltage source. Nanopillar electroporation may be used to increase the permeability of cell membranes to allow intracellular recording. Also provided are methods of device fabrication, and methods of use.

Abstract: This disclosure provide a nanopillar electrode device, comprising a substrate patterned with a plurality of metal pads. The device may further comprise a plurality of nanopillars electrode arrays, wherein each nanopillar electrode array is attached to the substrate above a metal pad and electrically connected to the pad. The device may further comprise and a chamber surrounding the nanopillar electrodes, which can be used for culturing cells of interest for recording action potentials. The nanopillar electrode device may be configured to apply a voltage through the nanopillar electrodes from a voltage source. Nanopillar electroporation may be used to increase the permeability of cell membranes to allow intracellular recording. Also provided are methods of device fabrication, and methods of use.

Abstract: This disclosure provide a nanopillar electrode device, comprising a substrate patterned with a plurality of metal pads. The device may further comprise a plurality of nanopillars electrode arrays, wherein each nanopillar electrode array is attached to the substrate above a metal pad and electrically connected to the pad. The device may further comprise and a chamber surrounding the nanopillar electrodes, which can be used for culturing cells of interest for recording action potentials. The nanopillar electrode device may be configured to apply a voltage through the nanopillar electrodes from a voltage source. Nanopillar electroporation may be used to increase the permeability of cell membranes to allow intracellular recording. Also provided are methods of device fabrication, and methods of use.