Abstract: A combined hydrogenation process and system for producing chemical raw materials are provided. The process has the following steps: (1) performing a hydrogenation pretreatment reaction on a wax oil raw material and hydrogen-containing gas, mixing the hydrogenated wax oil obtained by means of the reaction and a light diesel oil fraction, and performing a first hydrocracking reaction to obtain a first hydrocracking material flow; (2) separating and fractionating the first hydrocracking material flow to obtain a diesel oil fraction; and (3) performing a second hydrocracking reaction on the diesel oil fraction obtained in step (2) to obtain a second hydrocracking material flow, and separating and fractionating the second hydrocracking material flow. The process can transform all the high aromatics inferior diesel oil raw materials and wax oil raw materials into light naphtha, heavy naphtha tail oil and other high value-added products.

Abstract: Some embodiments of the disclosure use human peripheral blood for ctDNA sequencing or tumor tissues for whole exome sequencing, screen out mutation sites to perform antigen epitope prediction, connect and synthesize an expression gene sequence of mutant peptides. Other embodiments of the disclosure construct a lentiviral vector, package the lentivirus, transfect an APC cell to complete transformation of a specific LV cell, co-culture in vitro with PBMC separated from the peripheral blood, screen out an effective polypeptide, and transform common T cells into RFF cells. Suppressive signaling molecules include one or more of PD-1, Tim-3, LAG3, CTLA-4, BTLA, VISTA, CD160, and 2B4 (CD244). Antigen presenting cells include one or more of PBMC, a dendritic cell, neutrophil, B lymphocyte, and macrophage.

Abstract: The present invention discloses a gene OsNia3 of a rice nitrate reductase NIA3 protein. The cDNA sequence of the gene is as set out in SEQ ID NO.1, and the rice NIA3 protein encoded by it has an amino acid sequence as set out in SEQ ID NO.2. A homozygous mutant in which the rice gene OsNia3 is knocked out and a homozygous line in which the OsNia3 is over-expressed are obtained by utilizing a transgenic technology. It has been discovered by analysis that the line in which the OsNia3 gene is knocked out has a shortened plant height and a shorted growth period; while the line in which the OsNia3 is over-expressed has a relatively high plant height and a prolonged growth period.

Abstract: Some embodiments of the disclosure use human peripheral blood for ctDNA sequencing or tumor tissues for whole exome sequencing, screen out mutation sites to perform antigen epitope prediction, connect and synthesize an expression gene sequence of mutant peptides. Other embodiments of the disclosure construct a lentiviral vector, package the lentivirus, transfect an APC cell to complete transformation of a specific LV cell, co-culture in vitro with PBMC separated from the peripheral blood, screen out an effective polypeptide, and transform common T cells into RFF cells. Suppressive signaling molecules include one or more of PD-1, Tim-3, LAG3, CTLA-4, BTLA, VISTA, CD160, and 2B4 (CD244). Antigen presenting cells include one or more of PBMC, a dendritic cell, neutrophil, B lymphocyte, and macrophage.