Patents by Inventor Zinka Brkic

Zinka Brkic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8524657
    Abstract: The present invention provides a compound of formula I, II, III and IV as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: September 3, 2013
    Assignee: University of Wollongong
    Inventors: Timothy Patrick Boyle, John Barnard Bremmer, Zinka Brkic, Jonathan Alan Victor Coates, Neal Kevin Dalton, John Joseph Deadman, Paul Anthony Keller, Jody Morgan, Stephen Geoffrey Pyne, David Ian Rhodes, Mark James Robertson
  • Publication number: 20110312875
    Abstract: The present invention provides a compound of formula I, II, III and IV as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.
    Type: Application
    Filed: August 2, 2011
    Publication date: December 22, 2011
    Applicant: UNIVERSITY OF WOLLONGONG
    Inventors: Timothy Patrick Boyle, John Barnard Bremner, Zinka Brkic, Jonathan Alan Victor Coates, Neal Kevin Dalton, John Deadman, Paul Anthony Keller, Jody Morgan, Stephen Geoffrey Pyne, David Ian Rhodes, Mark James Robertson
  • Patent number: 8039430
    Abstract: The present invention provides a compound of formula (I), (II), (III) and (IV) as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: October 18, 2011
    Assignee: University of Wollongong
    Inventors: Timothy Patrick Boyle, John Barnard Bremner, Zinka Brkic, Jonathan Alan Victor Coates, Neal Kevin Dalton, John Joseph Deadman, Paul Anthony Keller, Jody Morgan, Stephen Geoffrey Pyne, David Ian Rhodes, Mark James Robertson
  • Publication number: 20080300287
    Abstract: The present invention provides a compound of formula (I), (II), (III) and (IV) as defined herein and pharmaceutically acceptable derivatives thereof. The present invention further provides use of the compounds of the present invention in the treatment of bacterial infection and in the treatment of HIV infection. Also provided are pharmaceutical compositions comprising the compounds of the present invention.
    Type: Application
    Filed: September 21, 2005
    Publication date: December 4, 2008
    Applicant: UNIVERSITY OF WOLLONGONG
    Inventors: Timothy Patrick Boyle, John Barnard Bremner, Zinka Brkic, Jonathan Alan Victor Coates, Neal Kevin Dalton, John Deadman, Paul Anthony Keller, Jody Morgan, Stephen Geoffrey Pyne, David Ian Rhodes, Mark James Robertson
  • Patent number: 5466686
    Abstract: The invention relates to the novel 4-oxo-azetidine-2-sulfonic acid amides and their salts of the formula I ##STR1## wherein the radicals have the meanings: R.sup.1 =hydrogen, halogen;R.sup.2 =hydrogen, halogen, NH.sub.2, C.sub.6 H.sub.5 CH.sub.2 CONH, C.sub.6 H.sub.5 OCH.sub.2 CONH, phthalimido, o-MeNHCOC.sub.6 H.sub.4 CONH, isoxazolylcarbonylamino;R.sup.3 =hydrogen, Me.sub.2 C.dbd.C--COOMe, H.sub.2 C.dbd.C(Me)--CH--COOMe, Me.sub.2 C.dbd.C--COOCH.sub.2 C.sub.6 H.sub.5, H.sub.2 C.dbd.C(Me)CH--COOCH.sub.2 C.sub.6 H.sub.4 NO.sub.2 -p, Me.sub.2 C.dbd.C--COOCH.sub.2 C.sub.6 H.sub.4 NO.sub.2 -p, Me.sub.2 C.dbd.C--COOCH.sub.2 C.sub.6 H.sub.4 Me-m, H.sub.2 C.dbd.C(Me)--CH--COOCH.sub.2 C.sub.6 H.sub.4 Me-m, Me.sub.2 C.dbd.C--COOH;R.sup.4 =hydrogen or sodium andR.sup.5 =hydrogen, alkyl, benzyl or heterocycle, i.e. isoxazole or pyrazole etc.
    Type: Grant
    Filed: September 3, 1993
    Date of Patent: November 14, 1995
    Assignee: PLIVA and PLIVA Handels GmbH
    Inventors: Mice Kovacevic, Jure J. Herak, Zora Mandic, Irena Lukic, Mirjana Tomic, Zinka Brkic
  • Patent number: 5446038
    Abstract: 5-Thia-1,4-diazabicyclo[4.2.0]octane-3,8-dioxo analogs of .beta.-lactam, processes for the preparation thereof and the use thereofDisclosed are novel 5-thia-1,4-diazabicyclo[4.2.0]octane-3,8-dioxo .beta.-lactam analogs of the general formula I ##STR1## wherein R.sup.1 is hydrogen or halo;R.sup.2 is hydrogen, halo, amino, PhCH.sub.2 CONH, PhOCH.sub.2 CONH, phthalimido, o-MeNHCO-C.sub.6 H.sub.4 -CONH, isoxazolylcarboxamido;R.sup.3 is hydrogen, alkyl, benzyl, heterocycle, e.g. isoxazole, pyrazole etc., andn may be 1 or 2.They may be used as intermediates in preparing novel .beta.-lactam analogs or as active substances in formulations for antimicrobial therapy.
    Type: Grant
    Filed: November 12, 1993
    Date of Patent: August 29, 1995
    Assignee: PLIVA, farmaceutska, kemijska, prehrambena i kozmeticka industrija dionicko
    Inventors: Mice Kovacevic, Jure J. Herak, Zora Mandiec, Irena Lukic, Mirjana Tomic, Zinka Brkic
  • Patent number: 5250525
    Abstract: The invention relates to novel 4-oxo-azetidine-2-sulfonic acids and their salts or the formula I ##STR1## wherein: R.sup.1 =hydrogen, halogen, phenylacetamido;R.sup.2 =hydrogen, halogen, phenylacetamido, phenoxyacetamido, phthalimido, 5-methyl-3-o-chlorophenyl-isoxazole-4-carboxamido;R.sup.3 =hydrogen, alkali metal, alkaline earth metal, quaternary ammonium group;R.sup.4 =hydrogen, SO.sub.2 O.sup.-+ NBu.sub.4 -n, (CH.sub.3).sub.2 C.dbd.C--COOCH.sub.3, (CH.sub.3).sub.2 C.dbd.C--COOCH.sub.2 -Ph, (CH.sub.3).sub.2 C.dbd.C--COOCH.sub.2 --C.sub.6 H.sub.4 --NO.sub.2 -p, (CH.sub.3).sub.2 C.dbd.C--COOCH.sub.2 --C.sub.6 H.sub.4 --CH.sub.3 -m.The products (I) may be used as intermediates in the synthesis of beta-lactamic antibiotics or as components in antimicrobial preparations.
    Type: Grant
    Filed: February 11, 1992
    Date of Patent: October 5, 1993
    Assignee: Pliva Handels GmbH
    Inventors: Mice Kovacevic, Zorica Mandic, Mirjana Tomic, Zinka Brkic, Jure J. Herak, Irena Lukic