Patents by Inventor Ziqiang Yuan

Ziqiang Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for diagnosing non-small cell lung carcinoma
    Patent number: 8273701
    Abstract: The present invention relates to the constitutive activity of the Hedgehog pathway in non-small cell lung carcinoma (NSCLC). A method for diagnosing NSCLC by detecting the level of a component of the Hedgehog pathway is provided, as is a method for identifying subjects that will respond positively to treatment with a Hedgehog pathway antagonist. Methods for treating subjects with cancer or cancers resistant to Hedgehog pathway antagonists are also provided.
    Type: Grant
    Filed: August 14, 2006
    Date of Patent: September 25, 2012
    Assignee: Trustees of Dartmouth College
    Inventors: David J. Robbins, Ziqiang Yuan, John A. Goetz
  • Method for Diagnosing Non-Small Cell Lung Carcinoma
    Publication number: 20100029580
    Abstract: The present invention relates to the constitutive activity of the Hedgehog pathway in non-small cell lung carcinoma (NSCLC). A method for diagnosing NSCLC by detecting the level of a component of the Hedgehog pathway is provided, as is a method for identifying subjects that will respond positively to treatment with a Hedgehog pathway antagonist. Methods for treating subjects with cancer or cancers resistant to Hedgehog pathway antagonists are also provided.
    Type: Application
    Filed: April 12, 2006
    Publication date: February 4, 2010
    Inventors: David J. Robbins, Ziqiang Yuan, John A. Goetz
  • Compositions and Methods for Inhibiting Sonic Hedgehog Activity
    Publication number: 20080008768
    Abstract: The present invention relates to the use of sonic hedgehog antagonists in the prevention and treatment of cancer and other hyperproliferative diseases or disorders. Methods for identifying such antagonists are also provided.
    Type: Application
    Filed: November 9, 2005
    Publication date: January 10, 2008
    Inventors: David Robbins, Ziqiang Yuan, John Goetz, William Scott, Sheila Bell, Claire Schreiner