Abstract: Certain embodiments of the present invention provide a method for controlling Athetis lepigone, which comprises contacting Athetis lepigone with Cry1A protein. Aspects of the present invention can achieve control of Athetis lepigone by enabling plants to produce Cry1A protein in vivo, which can be lethal to Athetis lepigone. In still other instances, the method can control Athetis lepigone throughout the growth period of the plants and provide the plants with a full protection. Additionally, the method, in certain embodiments, can be one or more of stable, complete, simple, convenient, economical, pollution-free or residue-free.