Abstract: A process for producing a purified aqueous lithium (sulfate) solution including: processing a lithium-containing raw material to produce a crude aqueous solution containing lithium sulfate; contacting the crude solution with an organic medium, in an extraction step to produce a lithium-loaded organic medium and a raffinate; stripping said lithium-loaded organic medium by means of an aqueous acid stripping solution (e.g., sulfuric acid), to extract the lithium cations from the lithium-loaded medium, to produce: the purified aqueous lithium (sulfate) solution and a stripped organic medium; separating the purified lithium solution from the stripped organic medium; recycling the stripped organic medium to the extraction step, the organic medium including the stripped organic medium; subjecting the raffinate to electrolysis to produce: an alkali (sodium) hydroxide solution contaminated with lithium and a sulfuric acid stream; and recycling the alkali hydroxide and sulfuric acid streams for use within the process.

Abstract: Processes for preparing and purifying Pregabalin and salts thereof are provided.

Abstract: The invention relates to pure (R)-CMH and to the optical resolution of CMH-racemate, a key intermediate in the synthesis of (S)-Pregabalin. The invention also relates to the process for optically purifying (R)-CMH and to the process for isolating (S)-CMH from the mother liquor.

Abstract: The invention relates to pure (R)—CMH and to the optical resolution of CMH-racemate, a key intermediate in the synthesis of (S)-Pregabalin. The invention also relates to the process for optically purifying (R)—CMH and to the process for isolating (S)—CMH from the mother liquor.

Abstract: The present invention encompasses Pregabalin substantially free of Lactam and a process for obtaining Pregabalin substantially free of Lactam comprising extracting an acidic mixture containing a complex of Pregabalin with a strong mineral acid, with C3-8 alcohol; and combining the organic phase with an organic base.

Abstract: A Pregabalin having a low level of 3-isobutylglutaric acid is provided.

Abstract: This invention relates to an efficient process for converting gabapentin hydrochloride salt to gabapentin by liquid-liquid extraction using a counter-current extraction method.

Abstract: The invention relates to pure (R)—CMH and to the optical resolution of CMH-racemate, a key intermediate in the synthesis of (S)-Pregabalin. The invention also relates to the process for optically purifying (R)—CMH and to the process for isolating (S)—CMH from the mother liquor.

Abstract: The invention relates to pure (R)—CMH and to the optical resolution of CMH-racemate, a key intermediate in the synthesis of (S)-Pregabalin. The invention also relates to the process for optically purifying (R)—CMH and to the process for isolating (S)—CMH from the mother liquor.

Abstract: The invention encompasses amorphous montelukast sodium having less than about 50 ppm heptane or less than about 100 ppm hexane, less than about 150 ppm toluene, and less than about 2500 ppm C1-C5 alcohols, as well as processes for its preparation.

Abstract: Processes for preparing and purifying Pregabalin and salts thereof are provided.

Abstract: The invention relates to pure (R)—CMH and to the optical resolution of CMH-racemate, a key intermediate in the synthesis of (S)-Pregabalin. The invention also relates to the process for optically purifying (R)—CMH and to the process for isolating (S)—CMH from the mother liquor.

Abstract: The present invention encompasses Pregabalin substantially free of Lactam and a process for obtaining Pregabalin substantially free of Lactam comprising extracting an acidic mixture containing a complex of Pregabalin with a strong mineral acid, with a C3-8 alcohol; and combining the organic phase with an organic base.

Abstract: A Pregabalin having a low level of 3-isobutylglutaric acid is provided.