Abstract: A device for manual manipulation of a guidewire including a generally cylindrical, integrally formed, compressible element arranged along a longitudinal axis and being compressible transversely to the longitudinal axis and having first, second and third, respectively uncompressed, fully compressed and partially compressed operative orientations, the element in the fully compressed operative orientation defining an axial slot adapted for side mounting of the element onto a guidewire and the element in the partially compressed operative orientation being adapted for tightly engaging a guidewire in the slot such that axial and rotational movement of the element produces corresponding axial and rotational movement of the guidewire.