Patents by Inventor Ziwen QIU

Ziwen QIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11607448
    Abstract: The present disclosure discloses a whole avian-origin reverse genetic manipulation system and its use in producing a recombinant H7N9 avian influenza vaccine. The whole avian-origin reverse genetic manipulation system is an eight-plasmid reverse genetic manipulation system based on H5N2 subtype avian influenza D7 virus strain, which is comprised of 8 recombinant plasmids respectively containing PB2, PB1, PA, HA, NP, NA, M and NS gene fragments derived from H5N2 subtype avian influenza D7 virus strain. The genome of the recombinant H7N9 subtype avian influenza vaccine of the present disclosure is comprised of an NA gene and a modified HA gene derived from a highly pathogenic H7N9 subtype avian influenza virus strain, as well as PB2, PB1, PA, NP, M and NS genes derived from H5N2 subtype avian influenza D7 virus strain.
    Type: Grant
    Filed: April 22, 2022
    Date of Patent: March 21, 2023
    Assignee: SOUTH CHINA AGRICULTURAL UNIVERSITY
    Inventors: Wenbao Qi, Ming Liao, Yiqun Chen, Huanan Li, Bo Li, Jiahao Zhang, Ziwen Qiu
  • Publication number: 20220370594
    Abstract: The present disclosure discloses a whole avian-origin reverse genetic manipulation system and its use in producing a recombinant H7N9 avian influenza vaccine. The whole avian-origin reverse genetic manipulation system is an eight-plasmid reverse genetic manipulation system based on H5N2 subtype avian influenza D7 virus strain, which is comprised of 8 recombinant plasmids respectively containing PB2, PB1, PA, HA, NP, NA, M and NS gene fragments derived from H5N2 subtype avian influenza D7 virus strain. The genome of the recombinant H7N9 subtype avian influenza vaccine of the present disclosure is comprised of an NA gene and a modified HA gene derived from a highly pathogenic H7N9 subtype avian influenza virus strain, as well as PB2, PB1, PA, NP, M and NS genes derived from H5N2 subtype avian influenza D7 virus strain.
    Type: Application
    Filed: April 22, 2022
    Publication date: November 24, 2022
    Applicant: SOUTH CHINA AGRICULTURAL UNIVERSITY
    Inventors: Wenbao QI, Ming LIAO, Yiqun CHEN, Huanan LI, Bo LI, Jiahao ZHANG, Ziwen QIU
  • Patent number: D1023457
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: April 16, 2024
    Inventor: Ziwen Qiu