Patents by Inventor Zixiang GUO

Zixiang GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of amanita toxins and their conjugation to a cell binding molecule
    Patent number: 10836796
    Abstract: The present invention is related to novel cytotoxic agents, derivatives of Amanita toxins of Formula (I), wherein , -----, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, L, m, n and Q are defined herein, the preparation and the therapeutic uses in the targeted treatment of cancers, autoimmune disorders, and infectious diseases.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: November 17, 2020
    Assignee: HANGZHOU DAC BIOTECH CO., LTD.
    Inventors: Robert Yongxin Zhao, Qingliang Yang, Yuanyuan Huang, Shun Gai, Hangbo Ye, Chengyu Yang, Huihui Guo, Xiaomai Zhou, Hongsheng Xie, Qianqian Tong, Minjun Cao, Linyao Zhao, Junxiang Jia, Wenjun Li, Xiaotao Zuo, Chen Lin, Yifang Xu, Zixiang Guo
  • DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE
    Publication number: 20200079820
    Abstract: The present invention is related to novel cytotoxic agents, derivatives of Amanita toxins of Formula (I), wherein , - - - , R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, L, m, n and Q are defined herein, the preparation and the therapeutic uses in the targeted treatment of cancers, autoimmune disorders, and infectious diseases.
    Type: Application
    Filed: April 20, 2016
    Publication date: March 12, 2020
    Applicant: Hangzhou DAC Biotech Co., Ltd.
    Inventors: Robert Yongxin ZHAO, Qingliang YANG, Yuanyuan HUANG, Shun GAI, Hangbo YE, Chengyu YANG, Huihui GUO, Xiaomai ZHOU, Hongsheng XIE, Qianqian TONG, Minjun CAO, Linyao ZHAO, Junxiang JIA, Wenjun LI, Xiaotao ZUO, Chen LIN, Yifang XU, Zixiang GUO