Abstract: A ground simulation device and method for an on-orbit manipulation of a space manipulator is provided. The ground simulation device includes: a dual-arm robot, configured to simulate the space manipulator operating a target object; a suspension device, including a fixed post and passive rods, where the passive rods are movably connected with a top end of the fixed post, and the target object is suspended to the passive rods; and a simulation platform, configured to fix the dual-arm robot and the suspension device thereon. The ground simulation device provides the passive rods on the suspension device and suspends the target object to the passive rods, thus overcoming the gravity of the target object. In addition, the passive rods can drive the target object to move under an influence of an external force, achieving a similar suspension effect to that in space, and providing a desired, safe, and reliable implementation effect.

Abstract: Embodiments of the synthesis, radiolabeling and biological applications of an activatable tracer that undergoes intramolecular cyclization and aggregation upon activation by cleavage of a blocking moiety are provided. The probes of the disclosure allow for target-controlled self-assembly of small molecules in living subjects for imaging and drug delivery. The aggregated nanoprobes of the disclosure may be detectable optically, by PET detection, magnetic resonance imaging, and the like depending on the detectable reporter attached to the nanoprobe.

Abstract: A precision compensation mechanism of a full-automatic bidirectional flanging machine comprises an upper die X-direction fine adjustment assembly, an upper die Y-direction fine adjustment assembly, a lower die X-direction fine adjustment assembly and a lower die Y-direction fine adjustment assembly, wherein the fine adjustment assemblies each comprise N adjusting threaded sleeves, N adjusting screws and a threaded sleeve rotation driving device; wherein the N adjusting threaded sleeves are threaded into an upper opening or a lower opening of a C-shaped flanging beam along the length direction of an upper die or a lower die; the outer wall surfaces of the N adjusting threaded sleeves are threaded into the upper opening or the lower opening of the C-shaped flanging beam to form N screw thread pairs I with the thread pitch of P1.

Abstract: Embodiments of the synthesis, radiolabeling and biological applications of an activatable tracer that undergoes intramolecular cyclization and aggregation upon activation by cleavage of a blocking moiety are provided. The probes of the disclosure allow for target-controlled self-assembly of small molecules in living subjects for imaging and drug delivery. The aggregated nanoprobes of the disclosure may be detectable optically, by PET detection, magnetic resonance imaging, and the like depending on the detectable reporter attached to the nanoprobe.

Abstract: A precision compensation mechanism of a full-automatic bidirectional flanging machine comprises an upper die X-direction fine adjustment assembly, an upper die Y-direction fine adjustment assembly, a lower die X-direction fine adjustment assembly and a lower die Y-direction fine adjustment assembly, wherein the fine adjustment assemblies each comprise N adjusting threaded sleeves, N adjusting screws and a threaded sleeve rotation driving device; wherein the N adjusting threaded sleeves are threaded into an upper opening or a lower opening of a C-shaped flanging beam along the length direction of an upper die or a lower die; the outer wall surfaces of the N adjusting threaded sleeves are threaded into the upper opening or the lower opening of the C-shaped flanging beam to form N screw thread pairs I with the thread pitch of P1.

Abstract: Embodiments of the synthesis, radiolabeling and biological applications of an activatable tracer that undergoes intramolecular cyclization and aggregation upon activation by cleavage of a blocking moiety are provided. The probes of the disclosure allow for target-controlled self-assembly of small molecules in living subjects for imaging and drug delivery. The aggregated nanoprobes of the disclosure may be detectable optically, by PET detection, magnetic resonance imaging, and the like depending on the detectable reporter attached to the nanoprobe.