Patents by Inventor Ziyan Zhu

Ziyan Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11754577
    Abstract: A 3D ultrasound imaging device including an ultrasound probe assembly and echo analyzer. The ultrasound probe assembly includes a housing and an acoustic window abutted against the housing to form a sealed chamber, wherein the surface of the acoustic window contacts with the breast of the human body to be examined; an ultrasound transducer moves at a first speed back and forth within the sealed chamber and performs high-speed pre-scanning through the acoustic window to obtain initial ultrasound signals; the echo analyzer analyzes the initial ultrasound signals to determine a quality of a ultrasound image acquired by the high speed pre-scanning; and the ultrasound transducer then moves at a second speed to perform another scan to acquire new ultrasound signals. A 3D ultrasound imaging method is also disclosed.
    Type: Grant
    Filed: December 2, 2021
    Date of Patent: September 12, 2023
    Assignee: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
    Inventors: Zhiwei Shi, Ziyan Zhu, Lei Zhu
  • Publication number: 20230235390
    Abstract: The present invention provides a mass spectrometry-based method and a kit for genotyping of platelet and neutrophil antigens and glycoproteins, which are used for genotyping of platelet-specific antigens, platelet CD36 glycoproteins and neutrophil antigens; by designing an optimal primer combination, problems such as homologous sequences and rich GC are overcome, moreover, by improving amplification reaction conditions and using nucleic acid mass spectrometry as a platform, 35 platelet-specific antigen polymorphic sites, 10 CD36 polymorphic sites and 8 neutrophil antigen polymorphic sites can be simultaneously detected in 2 reactions. The present invention has the characteristics of high specificity and sensitivity, and fast and high throughput, and can be used in clinic, scientific research, platelet donor routine screening, etc.
    Type: Application
    Filed: January 19, 2023
    Publication date: July 27, 2023
    Inventors: Luyi YE, Huijun ZHU, Ruishu LI, Min FU, Ping LU, Ziyan ZHU
  • Publication number: 20230235396
    Abstract: The present invention provides a mass spectrometry-based method and kit for erythrocyte blood group genotyping. By taking nucleic acid mass spectrometry as a platform and by designing primer combinations and improving amplification reaction conditions, 61 blood group genetic sites in 21 erythrocyte blood group systems can be simultaneously detected in one reaction, rapid typing of the 21 erythrocyte blood group systems can be realized, and identified phenotypes are all clinically significant erythrocyte antigen phenotypes. The present invention has the characteristics of high sensitivity, strong specificity, simple operation, and rapid and high throughput. The present invention can be applied to difficult blood group identification, blood matching, rare blood group screening, scientific research, routine business development and the like in clinical practice.
    Type: Application
    Filed: January 19, 2023
    Publication date: July 27, 2023
    Inventors: Luyi YE, Qixiu YANG, Ziyan ZHU
  • Publication number: 20220091144
    Abstract: A 3D ultrasound imaging device including an ultrasound probe assembly and echo analyzer. The ultrasound probe assembly includes a housing and an acoustic window abutted against the housing to form a sealed chamber, wherein the surface of the acoustic window contacts with the breast of the human body to be examined; an ultrasound transducer moves at a first speed back and forth within the sealed chamber and performs high-speed pre-scanning through the acoustic window to obtain initial ultrasound signals; the echo analyzer analyzes the initial ultrasound signals to determine a quality of a ultrasound image acquired by the high speed pre-scanning; and the ultrasound transducer then moves at a second speed to perform another scan to acquire new ultrasound signals. A 3D ultrasound imaging method is also disclosed.
    Type: Application
    Filed: December 2, 2021
    Publication date: March 24, 2022
    Inventors: Zhiwei SHI, Ziyan ZHU, Lei ZHU
  • Patent number: 11231431
    Abstract: A 3D ultrasound imaging device including an ultrasound probe assembly and echo analyzer. The ultrasound probe assembly includes a housing and an acoustic window abutted against the housing to form a sealed chamber, wherein the surface of the acoustic window contacts with the breast of the human body to be examined; an ultrasound transducer moves at a first speed back and forth within the sealed chamber and performs high-speed pre-scanning through the acoustic window to obtain initial ultrasound signals; the echo analyzer analyzes the initial ultrasound signals to determine a quality of a ultrasound image acquired by the high speed pre-scanning; and the ultrasound transducer then moves at a second speed to perform another scan to acquire new ultrasound signals. A 3D ultrasound imaging method is also disclosed.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: January 25, 2022
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Zhiwei Shi, Ziyan Zhu, Lei Zhu
  • Patent number: 10266882
    Abstract: Disclosed are a human rare blood type detection method, a kit, a rapid screening method and applications thereof. By using multiple pairs of PCR specific primers directing to the SNP loci of multiple rare blood types, the SNP loci of multiple rare blood types are simultaneously detected in the same PCR reaction system; and the multiplex PCR detection method and a Pool detection method are combined to rapidly screen the human rare blood types.
    Type: Grant
    Filed: January 18, 2012
    Date of Patent: April 23, 2019
    Assignee: SHANGHAI BLOOD CENTRE
    Inventors: Luyi Ye, Ziyan Zhu, Zhonghui Guo, Yunlei He, Huanhuan Gao, Pan Wang, Li Xie, Aoxue Zhu, Wei Zhang, Wenjie Gao, Qixiu Yang
  • Patent number: 10166004
    Abstract: An ultrasonic contrast imaging method and apparatus thereof. The method includes acquiring N frames of contrast image in an imaging period; projecting the N frames of contrast image to obtain a projection result image of the N frames of contrast image, wherein an nth group of original contrast image is projected in a projection template to obtain a projection result image of an nth frame of original contrast image, wherein the projection template is one frame of the nth group of original contrast image, and n is a positive integer greater than or equal to 1 and less than or equal to N, wherein the nth group of original contrast images is within a projection period and includes the nth original contrast image, and the projection period is a fixed value less than the imaging period; and displaying or storing the projection result image.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: January 1, 2019
    Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
    Inventors: Ziyan Zhu, Maodong Sang, Yongqiang Dong
  • Publication number: 20170071574
    Abstract: Disclosed is an ultrasonic contrast imaging method and an apparatus thereof.
    Type: Application
    Filed: June 24, 2015
    Publication date: March 16, 2017
    Inventors: Ziyan Zhu, Maodong Sang, Yongqiang Dong
  • Publication number: 20160302759
    Abstract: A 3D ultrasound imaging device including an ultrasound probe assembly and echo analyzer. The ultrasound probe assembly includes a housing and an acoustic window abutted against the housing to form a sealed chamber, wherein the surface of the acoustic window contacts with the breast of the human body to be examined; an ultrasound transducer moves at a first speed back and forth within the sealed chamber and performs high-speed pre-scanning through the acoustic window to obtain initial ultrasound signals; the echo analyzer analyzes the initial ultrasound signals to determine a quality of a ultrasound image acquired by the high speed pre-scanning; and the ultrasound transducer then moves at a second speed to perform another scan to acquire new ultrasound signals. A 3D ultrasound imaging method is also disclosed.
    Type: Application
    Filed: June 30, 2016
    Publication date: October 20, 2016
    Inventors: Zhiwei SHI, Ziyan ZHU, Lei ZHU
  • Publication number: 20140221246
    Abstract: Disclosed are a human rare blood type detection method, a kit, a rapid screening method and applications thereof. By using multiple pairs of PCR specific primers directing to the SNP loci of multiple rare blood types, the SNP loci of multiple rare blood types are simultaneously detected in the same PCR reaction system; and the multiplex PCR detection method and a Pool detection method are combined to rapidly screen the human rare blood types.
    Type: Application
    Filed: January 18, 2012
    Publication date: August 7, 2014
    Applicant: SHANGHAI BLOOD CENTER
    Inventors: Luyi Ye, Ziyan Zhu, Zhonghui Guo, Tunlei He, Huanhuan Gao, Pan Wang, Li Xie, Aoxue Zhu, Wei Zhang, Wenji Gao, Qixiu Yang