Abstract: The invention relates to a locking structure for the cover of a pickup truck, including fixed side frames and locking frame. The locking slot is provided on the fixed side frame. The locking frame comprises the horizontal frame body and connecting pieces. The connecting piece is provided with a locking box and the locking piece and reset piece are arranged in the locking box. The locking box is set with the first button and the second button. When touching the first button, the locking piece will pop out and the second button will bulge outward. Pressing on the second button will cause the locking piece to contract, and it will make the locking box pop up. This structure is easy to operate and simple.