Abstract: A apparatus and method to treat patients with acute decompensated heart failure (ADHF), heart failure or another fluid overload condition, that includes: administrating a diuretic to the patient to increase urine output of the patient; monitoring a rate or amount of urine output by the patient after administration of the diuretic; infusing a hydration liquid into the patient to induce an increase in the urine output; and adjusting the rate or amount of the hydration liquid infused into the patient to achieve a target fluid loss in the patient.

Abstract: The present technology is generally directed to flow cartridges configured to measure and/or detect analytes in urine. A representative flow cartridge includes a urine inlet configured to receive urine from a patient, a flow channel fluidly coupled to the urine inlet, and sensors fluidly coupled to the flow channel that are configured to measure parameters of the urine flow. The sensors are aligned with corresponding sensing zones of the flow channel and are operable to generate sensor data based on urine flow through the sensing zones. In some embodiment, the sensor data is used to provide fluid therapy to the patient by adjusting an amount or rate of diuretic and/or hydration fluid based on the sensor data.

Abstract: A apparatus and method to treat patients with acute decompensated heart failure (ADHF), heart failure or another fluid overload condition, that includes: administrating a diuretic to the patient to increase urine output of the patient; monitoring a rate or amount of urine output by the patient after administration of the diuretic; infusing a hydration liquid into the patient to induce an increase in the urine output; and adjusting the rate or amount of the hydration liquid infused into the patient to achieve a target fluid loss in the patient.

Abstract: Methods and devices for treating patients having cardiopulmonary disease such as cardiac arrhythmias, ventricular arrhythmias, pulmonary hypertension, or heart failure comprising a tracheal approach. The method includes ablating a deep cardiac plexus of a patient by advancing an treatment apparatus into a trachea of the patient, extending an ablative energy delivery element of the treatment apparatus through a wall of the trachea at a level of the trachea proximate a tracheal bifurcation, positioning the ablative energy delivery element at a target space between the trachea, an aorta and a pulmonary artery, and ablating, by the ablative energy delivery element, tissue within the target space to substantially disable the deep cardiac plexus.

Abstract: A treatment apparatus including: a bronchoscope including a flexible shaft having working channel; a transbronchial ablation probe configured to extend from a distal end of the working channel and extend thru a wall of a trachea and into tissue outside of the trachea; and a stabilization element mounted to a distal portion of the flexible shaft, wherein the stabilization element is configured to brace the distal portion against the wall of the trachea while the transbronchial ablation probe is extended through the wall of the trachea.

Abstract: A medical device assembly including: an lung reduction device including a vertex, a first arm having an end connected to the vertex, and a second arm having an end connected to vertex, wherein the first and second arms extend into a respective one of airway branches in the lung and the vertex seats upstream of a bifurcation of the airway branches, wherein the first and second arms apply a bias force to the airway branches and thereby reduce a section of the lung near the airway branches; a bronchoscope including a channel housing the lung reduction device and having an opening to the channel through which the lung reduction device is deployed, and a pusher device associated with the bronchoscope and adapted to push the lung reduction device from the working channel to advance the first and second arms into the airway branches.