Abstract: A method comprising receiving, as input, physiological parameters data measured in a human subject in response to an administered test question protocol comprising (a) a plurality of test question segments, each comprising at least one test question, and (b) a recovery period following each of the test question segments; determining a stress signal associated with the test question protocol, based, at least in part, on one or more states of stress detected in the physiological parameters data; temporally associating values of the stress signal with the plurality of test question segments and the recovery periods; and calculating, for at least some of the test question segments, a segment psychophysiological response score associated with the responses by the subject, based on an analysis of the temporally associated values of the stress signal.