Patents by Inventor Zoltán HUJBER

Zoltán HUJBER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHLOROTOXIN DERIVATIVES AND USE THEREOF
    Publication number: 20240115717
    Abstract: Chlorotoxin derivatives containing amino acid sequence X0X1CMPCXS1XS2XS3DHXS4XS5ARRCX2X3CCGGYGX4CFGYQC LCX5X6X7X8 wherein (i) the N-terminal X0X1 cluster is AM, 0M, or 00; (ii) the solubility XS1XS2XS3XS4XS5 cluster is FTTQT, FTTES, SSSQT, SSSES, FSSQT, FSSES, or FSSQS; (iii) the internal X2X3X4 cluster is DKR, RDK, KDR, IKY, HKW, DRK, LKQ, KKK; and (iv) the C-terminal X5X6X7X8 cluster is N000, R000, NR00, NRG0, NRGY, NRRR, or RRRR; 0 denotes a position where no amino acid is present; the chlorotoxin derivative has a relative human MMP-2 binding that is at least 1.62 times higher than the wild-type chlorotoxin of SEQ ID NO: 1.
    Type: Application
    Filed: December 28, 2021
    Publication date: April 11, 2024
    Applicant: VRG THERAPEUTICS KFT.
    Inventors: Sándor FARKAS, Zoltán TAKÁCS, János NACSA, Gábor RÁCZ, Péter HORNYÁK, Zoltán HUJBER, Daniel CIOCA