Patents by Inventor Zoltan FULOP

Zoltan FULOP has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240091377
    Abstract: The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 ?m.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 21, 2024
    Applicant: Oculis Operations Sarl
    Inventors: Thorsteinn Loftsson, Zoltan Fulop
  • Publication number: 20240058360
    Abstract: The present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a drug which is prone to oxidation, said method comprising the addition of an additive to prevent oxidation of the drug which is prone to oxidation. In particular, the present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a corticosteroid, said method comprising the addition of an additive to prevent oxidation of the corticosteroid. The present disclosure also relates to a composition comprising a corticosteroid and an additive to prevent oxidation of the corticosteroid.
    Type: Application
    Filed: October 26, 2023
    Publication date: February 22, 2024
    Applicant: Oculis Operations Sarl
    Inventors: Thorsteinn Loftsson, Zoltan Fulop
  • Publication number: 20240058358
    Abstract: The present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a drug which is prone to oxidation, said method comprising the addition of an additive to prevent oxidation of the drug which is prone to oxidation. In particular, the present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a corticosteroid, said method comprising the addition of an additive to prevent oxidation of the corticosteroid. The present disclosure also relates to a composition comprising a corticosteroid and an additive to prevent oxidation of the corticosteroid.
    Type: Application
    Filed: October 26, 2023
    Publication date: February 22, 2024
    Applicant: Oculis Operations Sarl
    Inventors: Thorsteinn Loftsson, Zoltan Fulop
  • Publication number: 20240058361
    Abstract: The present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a drug which is prone to oxidation, said method comprising the addition of an additive to prevent oxidation of the drug which is prone to oxidation. In particular, the present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a corticosteroid, said method comprising the addition of an additive to prevent oxidation of the corticosteroid. The present disclosure also relates to a composition comprising a corticosteroid and an additive to prevent oxidation of the corticosteroid.
    Type: Application
    Filed: October 26, 2023
    Publication date: February 22, 2024
    Applicant: Oculis Operations Sarl
    Inventors: Thorsteinn Loftsson, Zoltan Fulop
  • Publication number: 20240058359
    Abstract: The present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a drug which is prone to oxidation, said method comprising the addition of an additive to prevent oxidation of the drug which is prone to oxidation. In particular, the present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a corticosteroid, said method comprising the addition of an additive to prevent oxidation of the corticosteroid. The present disclosure also relates to a composition comprising a corticosteroid and an additive to prevent oxidation of the corticosteroid.
    Type: Application
    Filed: October 26, 2023
    Publication date: February 22, 2024
    Applicant: Oculis Operations Sarl
    Inventors: Thorsteinn Loftsson, Zoltan Fulop
  • Publication number: 20240058362
    Abstract: The present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a drug which is prone to oxidation, said method comprising the addition of an additive to prevent oxidation of the drug which is prone to oxidation. In particular, the present disclosure relates to a method for stabilizing the pH of an aqueous composition comprising a corticosteroid, said method comprising the addition of an additive to prevent oxidation of the corticosteroid. The present disclosure also relates to a composition comprising a corticosteroid and an additive to prevent oxidation of the corticosteroid.
    Type: Application
    Filed: October 26, 2023
    Publication date: February 22, 2024
    Applicant: Oculis Operations Sarl
    Inventors: Thorsteinn Loftsson, Zoltan Fulop
  • Publication number: 20230042785
    Abstract: The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsus-pension including an active agent complex having a diameter of less than about 100 µm.
    Type: Application
    Filed: October 26, 2022
    Publication date: February 9, 2023
    Inventors: Thorsteinn LOFTSSON, Zoltan FULOP
  • Publication number: 20230037486
    Abstract: The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 ?m.
    Type: Application
    Filed: September 28, 2022
    Publication date: February 9, 2023
    Inventors: Thorsteinn LOFTSSON, Zoltan FULOP
  • Publication number: 20220354869
    Abstract: A method is described of stabilizing the pH of an aqueous composition including a drug that is prone to oxidation. The method includes adding an additive to prevent oxidation of the drug that is prone to oxidation. Also described, is a method of stabilizing the pH of an aqueous composition including a corticosteroid, the method including adding an additive to prevent oxidation of the corticosteroid. Further, a composition is described that includes a corticosteroid and an additive to prevent oxidation of the corticosteroid.
    Type: Application
    Filed: June 30, 2020
    Publication date: November 10, 2022
    Inventors: Thorsteinn LOFTSSON, Zoltán FÜLÖP
  • Patent number: 11491240
    Abstract: The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 ?m.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: November 8, 2022
    Assignee: OCULIS SA
    Inventors: Thorsteinn Loftsson, Zoltan Fulop
  • Publication number: 20220008555
    Abstract: The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 ?m.
    Type: Application
    Filed: September 28, 2021
    Publication date: January 13, 2022
    Inventors: Thorsteinn LOFTSSON, Zoltan FULOP
  • Publication number: 20210386067
    Abstract: The present invention relates pesticidal complexes, pesticidal delivery systems and compositions, as well as processes of preparation and uses thereof. The present invention also relates to the use of cyclodextrins for increasing biological activity and improving uptake, penetration, retention and/or bioavailability of agrochemicals such as pesticides.
    Type: Application
    Filed: October 24, 2019
    Publication date: December 16, 2021
    Applicant: Adama Makhteshim Ltd.
    Inventors: Shimon Amselem, Lital Koren, Tamás Sohajda, Zoltán Fülöp, István Puskás
  • Patent number: 11135311
    Abstract: The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 ?m.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: October 5, 2021
    Assignee: OCULIS SA
    Inventors: Thorsteinn Loftsson, Zoltan Fulop
  • Publication number: 20190343846
    Abstract: The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 ?m.
    Type: Application
    Filed: November 29, 2017
    Publication date: November 14, 2019
    Inventors: Thorsteinn LOFTSSON, Zoltan FULOP
  • Publication number: 20180147297
    Abstract: The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 ?m.
    Type: Application
    Filed: November 29, 2017
    Publication date: May 31, 2018
    Inventors: Thorsteinn LOFTSSON, Zoltan FULOP