Abstract: A four-way ball valve having a valve housing and four fluid connection channels arranged therein, a valve ball which can be rotated around an axis of rotation and has a first ball passage channel and a second ball passage channel, three sealing seats for positioning the ball, wherein three fluid connection channels are associated with a respective sealing seat, a drive shaft connected with the ball, and an actuator for rotating the ball, wherein the four fluid connection channels are arranged and the first ball passage channel and the second ball passage channel are wherein at least two switching states of the valve are set by rotation of the ball, wherein two of the fluid connection channels are connected to one another through the first ball passage channel, and the third fluid connection channel is connected to the fourth fluid connection channel through the second ball passage channel.

Abstract: Our invention relates to catalysts and their use in the synthesis and conversion of alpha-olefin-containing products, essentially alpha-olefins, primarily from paraffins of renewable origin, having a carbon number of 11-45, and mixtures thereof, which mixtures contain paraffins having a carbon number of 11-45. The main steps of the process are the heterogeneous catalytic dehydrogenation of paraffin with a new zeolite-supported catalyst based on Pt, Pd or Ni, and then the conversion of the resulting olefin-containing product mixture, containing mainly straight-chain internal monoolefins, to lower homologous alpha-olefins—namely, the homogeneous or heterogeneous catalytic ethenolysis by using a ruthenium complex metathesis catalyst (i.e.

Abstract: A ball valve according to an exemplary embodiment of the present invention may comprise: an actuator; a housing having an interior space and a plurality of through-holes exposing the interior space, the through-holes including an inlet hole through while a refrigerant flows in, an outlet hole through which the refrigerant flows out, and a connection hole which is connected to the actuator; a ball having a flow path through which the refrigerant flows in connection with the inlet hole and the outlet hole, and being rotated by a rotary shaft of the actuator in the interior space; a sheet having a flow hole, through which the refrigerant passes in communication with the outlet hole, and arranged to be in contact with the ball between the housing and the ball so as to support the ball; and a sealing member placed between the seat and the housing.

Abstract: Provided is a compound, including a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein W is a direct bond or an optionally substituted C, and if W is a direct bond, then X1, X2, X3, and X4 are each independently H, OH, or an electrophile, and optionally one pair selected from X1 and X2, X2 and X3, and X3 and X4 forms a five-membered ring including one or more heteroatom, wherein the one or more heteroatom is selected from O, N, and S, and the five-membered ring is optionally substituted with a ?C, an ?S, or an electrophile, and Y1, Y2, Y3, Y4 and Y5 are each independently selected from H, CH3, OH, O—CH3, and NO2, and an electrophile, and optionally Y2 and Y3 form a five-membered ring including one or more heteroatom, wherein the one or more heteroatom is selected from O, N, and S, and the five-membered ring is optionally substituted with a ?C, ?S, or an electrophile.

Abstract: The present disclosure relates to a computer implemented method performed by a gaming system. In particular, the present disclosure relates to a scheme for further improving a randomness in a game provided by means of the gaming system. The present disclosure also relates to a corresponding gaming system and a computer program product.

Abstract: The present disclosure relates to a computer implemented method performed by a gaming system. In particular, the present disclosure relates to a scheme for further improving a randomness in a game provided by means of the gaming system. The present disclosure also relates to a corresponding gaming system and a computer program product.

Abstract: A suction dampening device comprises a housing with an inlet port formed therein and a valve case disposed adjacent the inlet port. The valve case includes at least one opening formed therein. A valve core is slidably disposed within the valve case. A lever having an axis of rotation fixed to a portion of the valve case includes a first lever arm disposed to a first side of the axis of rotation and a second lever arm disposed to a second side of the axis of rotation. The second lever arm abuts an outer circumferential surface of the valve core. A spring element is disposed between the first lever arm and the valve core. The spring element is configured to apply a force to the first lever arm to cause the second lever arm to apply a lateral force to the valve core to dampen vibrations of the spring element.

Abstract: A suction dampening device comprises a housing with an inlet port formed therein and a valve case disposed adjacent the inlet port. The valve case includes at least one opening formed therein. A valve core is slidably disposed within the valve case. A lever having an axis of rotation fixed to a portion of the valve case includes a first lever arm disposed to a first side of the axis of rotation and a second lever arm disposed to a second side of the axis of rotation. The second lever arm abuts an outer circumferential surface of the valve core. A spring element is disposed between the first lever arm and the valve core. The spring element is configured to apply a force to the first lever arm to cause the second lever arm to apply a lateral force to the valve core to dampen vibrations of the spring element.

Abstract: The present invention relates to a process for the synthesis of the 17-acetoxy-11?-[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione of formula (I): from 3,3-[1,2-etandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II):

Abstract: A fuel filter for motor vehicle, with a filter housing, a fuel inlet and a fuel outlet formed in the housing, as well as a cylindrical filter element arranged in the filter housing, and in a given case with terminal elements closing the ends of the filter element in a way enabling flow of the fuel, where a tubular antistatic insert is electrically connected by the internal surface of the folded paper filter element to the body potential of the vehicle as a grounding element, such that the configuration and installation of the filter element of the fuel filter is not affected.

Abstract: The present invention relates to a process for the synthesis of the known 17-acetoxy-11-?-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula (I) from 3,3-[1,2-ethandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II). Compound CDB-4124 belongs to the group of anti-hormones.

Abstract: Described herein is the discovery that certain mycobacterial serine/threonine protein kinases, particularly protein kinase G (PknG), are effective therapeutic targets for the treatment of mycobacterial infections. Furthermore, the present application refers to the use of mycobacterial serine/threonine protein kinases for developing methods for detection and determination of these kinases for recognizing and monitoring diseases and for controlling therapy of diseases.

Abstract: The present invention relates to compounds having a naphthyridine scaffold, and stereoisomeric forms, prodrugs, solvates, hydrates and/or pharmaceutically acceptable salts of these compounds as well as pharmaceutical compositions containing at least one of these naphthyridine derivatives together with pharmaceutically acceptable carrier, excipient and/or diluents. Said naphthyridine compounds have been identified as inhibitors of the protein kinase ROCK2, also known as Rho-kinase, and are useful for the treatment of cancers (tumor growth and metastases), erectile dysfunction, cardiovascular diseases, hypertension, angina pectoris, cerebral ischaemia, cerebral vasospasm, myocardial ischaemia, coronary vasospasm, heart failure, myocardial hypertrophy, atherosclerosis, restenosis, spinal cord injuries, neuronal degeneration, thrombotic disorders, asthma, glaucoma, inflammation, anti-viral diseases (e.g. HIV), and osteoporosis.

Abstract: An apparatus includes an internal and/or an external multiple-stage cooling device arranged coaxially with a drawing orifice of an extruder die and having multilevel tangential outlets for the coolant to stabilize a non-stabilized section of an expanded foil hose by spiral coolant streams. The internal device includes cooling units arranged at axial distances from each other, surrounding the foil section through a gap. Each cooling unit is connected to a coolant supply of selectively adjustable temperature. The external cooling device includes at least two cooling units arranged at an axial distance from each other, surrounding the foil section through a gap. Each cooling unit is provided with tangential inlets and is connected to a coolant supply to supply the coolant of selectively and individually adjustable temperature and/or volume and/or pressure.

Abstract: Described are heterobicyclic compounds such as 4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]thiopyran 3-carboxylic acid amides, 4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid amides, or benzo[b]thiophene-3-carboxylic acid amides and pharmaceutically acceptable salts thereof, the use of these derivatives for the prophylaxis and/or treatment of various diseases such as infectious diseases, including mycobacteriainduced infections and opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases and stroke, as well as compositions containing at least one heterobicyclic compound and/or pharmaceutically acceptable salts thereof. Furthermore, reaction procedures for the synthesis of the heterobicyclic compound are disclosed.

Abstract: Process for heat transfer between a solid object and a material layer, including the steps of: a) arranging a heat-discharging surface from a heat-receiving surface at a gap (R) for the flow (4); b) generating a speed difference between the surfaces by providing a relative movement thereof; c) increasing the speed (v1) of the flow (4) in the gap (R) compared to the speed of these surfaces (vH and/or vF) by the speed difference; d) maintaining a turbulent flow (4) in the gap (R) and carrying out the heat transfer by this flow (4). In the apparatus, the heat-receiving surface of the solid object (H) is formed on a structural part, e.g. rotor (2), which is relatively movably arranged in a housing (3) compared to the heat-discharging material layer (F). It is provided with a heat-removing unit and/or a heating unit.

Abstract: For imaging a two-dimensional target and ensuring scanning, photography and digitalization of the surface of a museum piece book opened at an angle slightly exceeding 45°, a method includes matching at least one optical unit adapted for influencing the direction of light rays falling onto it with the target, illuminating the target while directing an optical recording element to the optical unit and turning away the optical recording element, displacing in a receding manner from the plane of the target at a predetermined angle in a curved course compared to the optical axis originating from the target centre while tilting a mirror to half the extent of displacement, and mapping the pixels of the target reaching the optical recording element by projecting the rays originating from the pixels at right angles to the target through the optical unit to sensor elements.

Abstract: A fuel delivery module assembly for a vehicle which includes a fuel delivery module for supplying fuel from a fuel tank, a flange for attachment to a fuel tank and an emissions canister for controlling evaporative emissions. The fuel delivery module includes a reservoir for retaining fuel and a fuel pump for supplying fuel from the reservoir. The emissions canister is coupled to the fuel delivery module in a sliding relationship and is arranged such that the emissions canister can be displaced along a slide axis relative to the fuel delivery module between an installed position, in which the reservoir and emissions canister overlap parallel with the slide axis, and an installation position, in which the reservoir and emissions canister substantially do not overlap parallel with the slide axis. The invention also provides a fuel tank assembly comprising such a fuel delivery module assembly and to a method of positioning such a fuel delivery module assembly within a fuel tank.

Abstract: The invention relates to a non-contact sensor assembly having a casing with a cavity, a magnetic field sensor disposed within the cavity and a cap coupled to close the cavity. The cap has one or more openings through which pins, extending from the sensor or its associated circuit board extend. A sealant is located between the pin and the opening in the cap that hermetically seals the opening and the cavity. The non-contact sensor assembly may be used with a fuel level sensing device.