Patents by Inventor Zoltan Machaty

Zoltan Machaty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Motility-contrast imaging for oocyte and embryo viability assessment
    Patent number: 9829482
    Abstract: A method and system is provided for evaluating viability of oocytes and embryos comprising imaging an oocyte or embryo using motility contrast imaging; generating temporal contrast and spatial contrast data for the cells; generating a cell viability value as a function of the temporal and spatial contrast data; and comparing the cell viability value to a predetermined value indicative of a cell suitable for use in an in vitro fertilization program.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: November 28, 2017
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Ran An, David D. Nolte, Zoltan Machaty, John J. Turek
  • Motility-Contrast Imaging for Oocyte and Embryo Viability Assessment
    Publication number: 20170102376
    Abstract: A method and system is provided for evaluating viability of oocytes and embryos comprising imaging an oocyte or embryo using motility contrast imaging; generating temporal contrast and spatial contrast data for the cells; generating a cell viability value as a function of the temporal and spatial contrast data; and comparing the cell viability value to a predetermined value indicative of a cell suitable for use in an in vitro fertilization program.
    Type: Application
    Filed: September 13, 2013
    Publication date: April 13, 2017
    Applicant: Purdue Research Foundation
    Inventors: Ran An, David D. Nolte, Zoltan Machaty, John J. Turek
  • Motility-Contrast Imaging for Oocyte and Embryo Viability Assessment
    Publication number: 20150079621
    Abstract: A method and system is provided for evaluating viability of oocytes and embryos comprising imaging an oocyte or embryo using motility contrast imaging; generating temporal contrast and spatial contrast data for the cells; generating a cell viability value as a function of the temporal and spatial contrast data; and comparing the cell viability value to a predetermined value indicative of a cell suitable for use in an in vitro fertilization program.
    Type: Application
    Filed: September 13, 2013
    Publication date: March 19, 2015
    Applicant: Purdue Research Foundation
    Inventors: Ran An, David D. Nolte, Zoltan Machaty, John J. Turek
  • Capacitative calcium entry mechanism in porcine oocytes
    Publication number: 20030066100
    Abstract: Mammalian oocytes are contacted with a compound that activates a trp calcium channel. In this manner activation or maturation of the oocyte can be achieved.
    Type: Application
    Filed: July 9, 2002
    Publication date: April 3, 2003
    Inventors: Zoltan Machaty, Jagdeece Ramsoondar, Kenneth Bondioli
  • Complete oocyte activation using an oocyte-modifying agent and a reducing agent
    Patent number: 6211429
    Abstract: Provided is a method of parthenogenetically activating an unfertilized mammalian oocyte, comprising contacting an unfertilized mammalian oocyte with an oocyte-modifying agent followed by a reducing agent, wherein the mammalian oocyte is in contact with the oocyte-modifying agent and reducing agent, respectively, for a time and under conditions such that the unfertilized mammalian oocyte is activated. Also provided are methods for transplanting a nucleus from a cultured mammalian cell, mammalian embryo, mammalian fetus, or an adult mammal to a recipient mammalian oocyte; producing a cloned mammalian embryo; and producing a cloned mammal, as well as the cloned products produced by these methods. Finally, a method of studying genetic imprinting in mammals is also provided.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: April 3, 2001
    Assignee: The Curators of the University of Missouri
    Inventors: Zoltan Machaty, Randall S. Prather