Patents by Inventor Zoltan Toelgyesi

Zoltan Toelgyesi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AQUEOUS COMPOSITION OF APOMORPHINE FOR SUBCUTANEOUS ADMINISTRATION
    Publication number: 20180280465
    Abstract: The present invention relates to an aqueous composition comprising apomorphine or a pharmaceutically acceptable salt or solvate thereof, reduced glutathione (GSH) or a pharmaceutically acceptable salt thereof, and ascorbic acid or a pharmaceutically acceptable salt or derivative thereof, wherein the composition has a pH of about 3 to about 7.4. The aqueous composition according to the invention exhibits superior tolerability and an improved side effect profile, particularly a reduced occurrence of skin nodule formation and panniculitis, when administered subcutaneously. The invention further relates to the composition for use as a medicament, particularly for the treatment of Parkinson's disease.
    Type: Application
    Filed: September 28, 2016
    Publication date: October 4, 2018
    Inventors: Heinz SCHNAIT, Zoltán TÖLGYESI, Sabine SCHMIDT, Kerstin HARTWIG, Dieter Horst MEIER, Christian SELIGER
  • Granulating process and thus prepared granulate
    Patent number: 8927021
    Abstract: The present invention relates to a process for manufacturing microcrystalline ezetimibe containing granulate, wherein a) ezetimibe is dissolved; b) the dissolved ezetimibe is precipitated with water, which if necessary contains pharmaceutical excipients, preferably lauryl-sulfate derivatives, and c) granulates are formed from the obtained suspension by spraying the suspension onto pharmaceutical excipients. A further aspect of the present invention is the granulate obtained by the present process and the pharmaceutical composition containing such granulate.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: January 6, 2015
    Assignee: Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszventarsasag
    Inventors: Zoltan Toelgyesi, Zsolt Zsigmond, Gyoergy Ujfalussy, Magdolna Leventiszne Huszar, Peter Tonka-Nagy, Monika Agyagos
  • NEW GRANULATING PROCESS AND THUS PREPARED GRANULATE
    Publication number: 20120164227
    Abstract: The present invention relates to a process for manufacturing microcrystalline ezetimibe containing granulate, wherein a) ezetimibe is dissolved; b) the dissolved ezetimibe is precipitated with water, which if necessary contains pharmaceutical excipients, preferably lauryl-sulfate derivatives, and c) granulates are formed from the obtained suspension by spraying the suspension onto pharmaceutical excipients. A further aspect of the present invention is the granulate obtained by the present process and the pharmaceutical composition containing such granulate.
    Type: Application
    Filed: February 24, 2010
    Publication date: June 28, 2012
    Inventors: Zoltan Toelgyesi, Zsolt Zsigmond, Gyoergy Ujfalussy, Magdolna Leventiszne Huszar, Peter Tonka-Nagy, Monika Agyagos