Abstract: The present disclosure provides a high-temperature negative-pressure air exchange sterilizer and a sterilization method thereof. An air inlet is disposed at a bottom of a waterproof shell of the sterilizer, and an inlet filter is installed at the air inlet. Air entering from the air inlet is divided into two paths at a check valve. One path is connected with a negative-pressure fan through a pipeline B, and the other path is communicated with an air outlet through a pipeline A. A plurality of heating rods and temperature sensors are disposed in the pipeline A. The pipeline A is zigzag disposed at an upper part of the waterproof shell, and a thermal insulation material is disposed outside a zigzag part. A butterfly valve and an outlet filter screen are sequentially disposed at the air outlet in an air exhaust direction. The problem that viruses exhaled by breathing of an infected person are mixed in aerosol, so that a person in close contact with the infected person is likely to be infected is solved.

Abstract: The present application discloses an air purifier, including: a first body including a first housing; and a second body detachably connected to the first body and including a second housing, where buckles are arranged on the first housing, and snap-fit members are arranged on the second housing; the number of the buckles is greater than the number of the snap-fit members; and the first body in butt joint is enabled to rotate relative to the second body, so that the buckles can be hooked with the snap-fit members or separated from the snap-fit members. In the air purifier, a larger number of buckles are hooked with a smaller number of snap-fit members, so that disassembly and assembly operations can be simplified. Because the first body and the second body are detachable, the second body can be operated independently when the filter screen is detached.

Abstract: The invention relates to new crystal forms of compound (trans)-4-((2-cyclopropylethyl)amino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl) cyclohexanol trihydrochloride, its hydrate, or solvate, as shown in Formula I. The invention also relates to methods for preparation of the described compound, crystal form, and related intermediate compounds, as well as pharmaceutical compositions containing the compounds. Further described is, the use of the compounds or crystal forms in the production of a medicament for the treatment of a disease, symptom, or condition, or the use in treatment of a disease, symptom or condition.

Abstract: The present invention relates to the technical field of medicine, and specifically provides methods for preparing Icotinib, Icotinib hydrochloride, and intermediates thereof. These methods avoid the use of phosphorus oxychloride, thereby greatly reducing the emission of pollutants, which is of major benefits to the economy and environment.

Abstract: The present invention relates to the technical field of medicine, and specifically provides methods for preparing Icotinib, Icotinib hydrochloride, and intermediates thereof. These methods avoid the use of phosphorus oxychloride, thereby greatly reducing the emission of pollutants, which is of major benefits to the economy and environment.

Abstract: Disclosed is a method for preparing powder carrying nano gold by thermal decomposition, comprising the steps of: (1) providing a nano powder of artificial synthesized material or a natural mineral powder which particle size is in nano to micro scale as a carrier, preparing 0.2-5.0% (weight percentage concentration) gold bromide solution with deionized water and gold bromide, adding the carrier into the gold bromide solution, and a weight ratio of gold bromide and carrier is 1:1-1:1000, immersing the carrier into the solution for 0.5-4 hours in dark; (2) drying the immersed carrier and the solution at 50-90° C., and grinding the carrier to the fine mixed powders; and (3) heating the mixed powders obtained in step (2) at 200-350° C. for 0.5-3 hours in a heating apparatus flown argon gas or air at a flow rate of 1-10 L/min, and obtaining the carrier powder carrying nano gold after decreasing the heating temperature to room temperature under continuous air flow.

Abstract: Disclosed is a method for preparing nano-complex-powder comprising multiple components and silver. The method includes the steps of mixing 0.01-5.0% (weight percentage concentration) of silver nitrate solution with 0.001-5.0% of zinc nitrate solution, 0.001-5.0% of iron nitrate solution and 0.001-5.0% of copper nitrate solution, adding adequate amount of surfactant solution, and adding 0.001-1.0% of hydrazine hydrate gradually with stirring, and the solution is mixed for another 10-30 minutes to obtain a solution comprising multiple nano-complex-particle. After inertness, washing and drying at low temperature, the nano-complex-powder comprising multiple components and silver is obtained. The silver content in the product powder is about 40-99.6%, and the particle size is 10-100 nm.