Patents by Inventor Zora Mandiec

Zora Mandiec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-thia-1,4-diazabicyclo[4.2.0]octane-3,8-dioxo analogs of .beta.-lactam, processes for the preparation thereof and the use thereof
    Patent number: 5446038
    Abstract: 5-Thia-1,4-diazabicyclo[4.2.0]octane-3,8-dioxo analogs of .beta.-lactam, processes for the preparation thereof and the use thereofDisclosed are novel 5-thia-1,4-diazabicyclo[4.2.0]octane-3,8-dioxo .beta.-lactam analogs of the general formula I ##STR1## wherein R.sup.1 is hydrogen or halo;R.sup.2 is hydrogen, halo, amino, PhCH.sub.2 CONH, PhOCH.sub.2 CONH, phthalimido, o-MeNHCO-C.sub.6 H.sub.4 -CONH, isoxazolylcarboxamido;R.sup.3 is hydrogen, alkyl, benzyl, heterocycle, e.g. isoxazole, pyrazole etc., andn may be 1 or 2.They may be used as intermediates in preparing novel .beta.-lactam analogs or as active substances in formulations for antimicrobial therapy.
    Type: Grant
    Filed: November 12, 1993
    Date of Patent: August 29, 1995
    Assignee: PLIVA, farmaceutska, kemijska, prehrambena i kozmeticka industrija dionicko
    Inventors: Mice Kovacevic, Jure J. Herak, Zora Mandiec, Irena Lukic, Mirjana Tomic, Zinka Brkic