Abstract: In certain embodiments, a surgical contact lens system for ophthalmic treatment with a laser beam includes a patient contact lens and a surgical contact lens. The patient contact lens reduces one or more refractive errors of the eye and has a concave surface and a convex surface. The concave surface is to be disposed outwardly from a cornea of an eye. The surgical contact lens has an eye end to be disposed outwardly from the convex surface of the patient contact lens. The surgical contact lens includes a frame and an optical component coupled to the frame. The patient contact lens reduces pressure from the surgical contact lens to reduce corneal folding of a posterior surface of the cornea. The optical component of the surgical contact lens and the patient contact lens transmit the laser beam to treat the eye.

Abstract: In certain embodiments, an ophthalmic laser surgical system for treating a floater in a vitreous of an eye includes a floater detection system, a laser device, and a computer. The floater detection system determines the location of the floater in the vitreous of the eye. The laser device directs a laser beam along a laser beam path towards the floater. The computer accesses a three-dimensional scan pattern for the laser beam that yields a three-dimensional pulse pattern of laser pulses. The three-dimensional pulse pattern has a bubble shield pulse pattern at the posterior side of the three-dimensional pulse pattern. The bubble shield pulse pattern forms a bubble shield that reduces laser radiation exposure at a retina of the eye. The computer instructs the laser device to direct the laser beam towards the floater according to the three-dimensional scan pattern.

Abstract: The disclosure provides an ophthalmic surgical microscope including an optical axis. The ophthalmic surgical microscope also includes at least one light source configured to provide illumination having a wavelength range between 575 nm and 625 nm. The ophthalmic surgical microscope further includes a control device for directing the illumination at an acute angle relative to the optical axis of the microscope.

Abstract: A method for treating near-retina floaters includes dilating a pupil of an eye of a patient to at least 6.6 millimeters (mm). While the pupil is dilated to at least 6.6 mm, the method further includes emitting, by an optical delivery system, a plurality of pulses from a treatment laser into the eye of the patient, each pulse of the plurality of pulses having a diameter upon passing through the pupil that substantially fills the pupil and having a focus within 3 mm of a retina of the eye of the patient. Pulses may pass through adaptive optics that may be adjusted based on light emitted from the eye, such as two-photon fluorescence or second harmonic radiation, in order to reduce spot size at the focus.

Abstract: Described herein is a method for adjusting at least one optical characteristic of an intraocular lens. The method involves the use of a violet laser having a wavelength in the range of 380 nm to 460 nm. The violet laser can be used to correct post-operative refractive errors in intraocular lenses, while being noninvasive and safe.

Abstract: In certain embodiments, an ophthalmic laser surgical system for treating a target tissue in an eye includes a target detection system and a laser device. The target tissue has an optical breakdown threshold. The target detection system directs detection beams along a detection beam path towards the target tissue in a vitreous of the eye, and determines a location of the target tissue within the vitreous. The laser device includes a femtosecond laser that generates subthreshold laser pulses that have a pulse energy below the optical breakdown threshold of the tissue. The laser device directs a laser beam comprising the subthreshold laser pulses along a laser beam path towards the target tissue.

Abstract: Particular embodiments disclosed herein provide an apparatus for performing optometric measurements includes an optical coherence tomography (OCT) imaging system configured to output scanned parallel laser beams across a patient's eye. A line in the OCT image is identified, the line representing a retina of the patient's eye. A shape of the line is then used by the refractive error calculator to measure refractive error of the patient's eye. The height of the line due to curvature indicates degree of myopia or hyperopia. More complex curvature of the line corresponds to higher order aberrations. OCT images for a plurality of section planes may be used to calculate a wavefront elevation map.

Abstract: Particular embodiments disclosed herein enable psychophysical evaluation of vitreous floaters. One or more patient stimulus images are projected onto the patient's retina, the patient images including a stationary or mobile fixation target. While the patient stimulus images are displayed, images of the patient's retina are captured, such as using an SLO, and shadow images are derived from the images. The shadow images include representations of shadows cast by floaters. Observer stimulus images are generated from the shadow images and the patient stimulus images and projected onto the retinas of an observer, such as using a virtual reality display device.

Abstract: In certain embodiments, an ophthalmic laser surgical system for treating a floater in a vitreous of an eye includes a floater detection system, a laser device, and a computer. The floater detection system determines the location of the floater in the vitreous of the eye. The laser device directs a laser beam along a laser beam path towards the floater. The computer accesses a three-dimensional scan pattern for the laser beam that yields a three-dimensional pulse pattern of laser pulses. The three-dimensional pulse pattern has a bubble shield pulse pattern at the posterior side of the three-dimensional pulse pattern. The bubble shield pulse pattern forms a bubble shield that reduces laser radiation exposure at a retina of the eye. The computer instructs the laser device to direct the laser beam towards the floater according to the three-dimensional scan pattern.

Abstract: In certain embodiments, an ophthalmic laser system includes a laser device, an ophthalmic microscope, a z-direction sensor, and a controller. The laser device directs a laser beam towards a target within an eye. The ophthalmic microscope receives light from a focal point within the eye to provide an image of an object at the focal point. The z-direction sensor determines the z-position corresponding to the focal point of the ophthalmic microscope. The controller determines a position Z0, the z-position where the focal point of the ophthalmic microscope is at the retina of the eye; determines a position Z, the z-position where the focal point of the ophthalmic microscope is at the target within the eye; calculates a target-to-retina distance ?Z according to a difference between the position Z and the position Z0; and calculates a radiant exposure He at the retina according to the target-to-retina distance ?Z.

Abstract: Systems and methods for intraocular lens selection include receiving, by one or more computing devices implementing a prediction engine, pre-operative multi-dimensional images of an eye; extracting, by the prediction engine, pre-operative measurements of the eye based on the pre-operative images; estimating, by the prediction engine using a prediction model based on a machine learning strategy, a post-operative position of an intraocular lens based on the extracted pre-operative measurements; selecting a power of the intraocular lens based on the estimated post-operative position of the intraocular lens; and selecting the intraocular lens based on the selected power. In some embodiments, the systems and methods further include receiving post-operative multi-dimensional images of the eye after implantation of the selected intraocular lens, extracting post-operative measurements of the eye, and updating the prediction model based on the pre-operative measurements and the post-operative measurements.

Abstract: In certain embodiments, an ophthalmic laser system includes a laser device and a computer, where the laser device includes a laser and a phase modulator. The laser device directs a laser beam towards a target in an eye, where an intraocular lens (IOL) is disposed within the eye. The IOL has a phase profile that yields an IOL phase shift of light entering the eye. The laser generates the laser beam. The phase modulator has a phase front that yields a first phase shift of the laser beam that changes to a second phase shift when the laser beam reaches the IOL. The second phase shift is an inverse to the IOL phase shift.

Abstract: In certain embodiments, an ophthalmic surgical system for viewing an eye includes an ophthalmic microscope and a laser device. The ophthalmic microscope receives light reflected or scattered backwards from within the vitreous of the eye in order to provide an image of an object within the vitreous. The ophthalmic microscope includes a slit illumination source (which includes a light source and an optical element), a spectral filter, and oculars. The slit illumination source illuminates the eye with light, where the light source provides the light, and the optical element directs the light into the eye. The spectral filter filters out red spectral components of the light. The oculars receive the light from the eye in order to provide the image of the object. The laser device generates a laser beam to direct towards the object within the eye.

Abstract: In certain embodiments, an ophthalmic laser system for treating a floater in a vitreous of an eye includes a laser device that directs laser pulses towards the floater to yield cavitation bubbles that create a bubble jet to treat the floater. In some examples, the laser device includes a beam multiplexer that splits a laser beam into multiple beams that form the cavitation bubbles that create the bubble jet. In some examples, the laser device directs laser pulses towards the floater according to a pulse pattern that forms the cavitation bubbles that create the bubble jet.

Abstract: In certain embodiments, an ophthalmic laser surgical system for imaging and treating a target in an eye includes an imaging system with an optical coherence tomography (OCT) device that directs an OCT imaging beam along an imaging beam path towards the target in the eye, and generates OCT images from the OCT imaging beam reflected from the eye. The beam combining and alignment device aligns the OCT imaging beam and the laser beam. The laser-OCT xy-scanner: receives the OCT imaging beam from the imaging system, directs the OCT imaging beam along the imaging beam path towards the eye, and scans the OCT imaging beam in an xy-plane in the eye; and receives the laser beam from the laser device, directs the laser beam along the laser beam path aligned with the imaging beam path towards the eye, and scans the laser beam in the xy-plane in the eye.

Abstract: In certain embodiments, an ophthalmic laser surgical system for treating a floater in an eye comprises a scanning laser ophthalmoscope (SLO) device that: generates an SLO image of a floater shadow cast by the floater onto a retina of the eye, and provides an xy-location of the floater shadow, where the xy-location is related to the xy-scanner. An interferometer device provides a z-location of the floater, where the z-location is relative to the retina. A laser device generates a laser beam and includes a z-focusing component that focuses a focal point of the laser beam onto the z-location of the floater. An xy-scanner directs an SLO beam from the SLO device along an SLO beam path towards the xy-location of the floater shadow, and directs the laser beam from the laser device along the SLO beam path towards the xy-location of the floater shadow.

Abstract: An ophthalmic system for visualization of interactions between ocular matter and a probe tip of a probe within or in contact with an ocular space of an eye includes: a visualization tool having a field of view that includes at least a portion of the ocular space of the eye where the probe tip interfaces with the ocular matter; and a stroboscopic illumination source configured to stroboscopically illuminate at least the portion of the field of view at an illumination frequency. A method of operating a stroboscopic illumination source during an ophthalmic surgical procedure includes: identifying an illumination source type of the stroboscopic illumination source; identifying a probe type; identifying a first procedure trigger; and operating the stroboscopic illumination source based on the probe type, the illumination source type, and the first procedure trigger.

Abstract: According to certain embodiments, an ophthalmic surgical system for treating presbyopia comprises controllable components and a computer. The controllable components comprise a light source that generates a light beam and a scanner that directs a focal point of the light beam. The computer determines an ablation profile to remove tissue from a central region and a peripheral region of a cornea of a first eye of a pair of eyes. The ablation profile is designed to remove tissue from the central region to yield a protrusion to provide for near-vision, and to remove tissue from the peripheral region to correct to emmetropia.

Abstract: In certain embodiments, an ophthalmic surgical system for creating a lenticule in the cornea of an eye comprises controllable components (including a laser source and a scanner) and a computer. The laser source generates a laser beam, and the scanner directs the focal point of the laser beam. The computer determines a lenticule design for the lenticule having a posterior side and an anterior side. Either the posterior side or the anterior side has a central portion and a peripheral portion. The lenticule design is formed using a major lenslet and a minor lenslet, where the major lenslet is designed to correct to emmetropia. The lenticule design is formed by subtracting the minor lenslet from the major lenslet, where the subtraction of the minor lenslet yields the central portion. The computer instructs one or more of the controllable components to create the lenticule.

Abstract: In certain embodiments, an ophthalmic surgical system for creating a lenticule in the cornea of an eye comprises controllable components (including a laser source and a scanner) and a computer. The laser source generates a laser beam, and the scanner directs the focal point of the laser beam. The computer determines a lenticule design for the lenticule having a posterior side and an anterior side. Either the posterior side or the anterior side has a central portion and a peripheral portion. The lenticule design is formed using a major lenslet and a minor lenslet, where the major lenslet is designed to correct to emmetropia. The lenticule design is formed by subtracting the minor lenslet from the major lenslet, where the subtraction of the minor lenslet yields the central portion. The computer instructs one or more of the controllable components to create the lenticule.