Patents by Inventor Zsuzsa Somjai

Zsuzsa Somjai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Furfuryl derivatives of vinblastine-type bis-indoles, and pharmaceutical compositions containing them
    Patent number: 4753948
    Abstract: The invention relates to novel furfuryl derivatives of the general formula (I), ##STR1## wherein R.sub.1 stands for a hydrogen atom or an acetyl group,R.sub.2 stands for a hydroxyl or ethyl group of.beta.-position;R.sub.3 means an ethyl group of .alpha.-position;R.sub.4 represents a hydrogen atom; orR.sub.3 and R.sub.4 together represent an oxygen bridge; andB stands for a hydroxyl of an O-acyl group, as well as their acid addition salts and pharmaceutical preparations containing these compounds. Further on, the invention relates to a process for preparing these compounds and preparations.The compounds of the general formula (I) show a cytostatic activity with less toxicity than that of the commerically available known vinblastine-type bis-indole alkaloid drugs.
    Type: Grant
    Filed: June 12, 1986
    Date of Patent: June 28, 1988
    Assignee: Richter Gedeon Vegyeszeti Gyar R.T.
    Inventors: Csaba Szantay, Lajos Szabo, Katalin Honty, Tibor Keve, Tibor Acs, Sandor Eckhardt, Janos Sugar, Zsuzsa Somjai, Eva Ivan, Zsuzsa Kneffel