Patents by Inventor Zsuzsa Szondy

Zsuzsa Szondy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of a RAR-&ggr;-specific agonist ligand for increasing the rate of apoptosis
    Patent number: 6686386
    Abstract: The present invention relates to pharmaceutical and cosmetic compositions comprising at least one agonist ligand, which is specific for receptors of the RAR-&ggr; type, which are characterized as inducers of apoptosis in at least one cell population in which apoptosis can be induced by activating receptors of the RAR-&ggr; type. In one aspect of the present invention, there is provided a method of combating photoinduced or chronological ageing of skin, said method comprising administering an effective amount of at least one agonist ligand which is specific for receptors of the RAR-&ggr; type to combat photoinduced or chronological aging of skin, wherein the agonist ligand has a ratio R which is equal to or greater than 10.
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: February 3, 2004
    Assignee: Galderma Research & Development S.N.C.
    Inventors: Laszlo Fesus, Zsuzsa Szondy, Uwe Reichert
  • Use of a RAR-&ggr;-specific agonist ligand for increasing the rate of apoptosis
    Patent number: 6593359
    Abstract: The use of at least one &ggr;-RAR receptor-specific agonist ligand to prepare a pharmaceutical composition for increasing the rate of apoptosis in at least one cell population in which apoptosis may be induced by activating &ggr;-RAR receptors is disclosed. The composition is particularly useful for treating a disease or disorder related to an insufficient rate of apoptosis in at least one cell population in which apoptosis may be induced by activating &ggr;-RAR receptors. The use of at least one &ggr;-RAR receptor-specific agonist ligand as the apoptosis inducer in a cosmetic composition is also disclosed. Said composition may be used to prevent and/or control photo-ageing or chronological ageing of the skin.
    Type: Grant
    Filed: July 15, 1998
    Date of Patent: July 15, 2003
    Assignee: Centre International de Recherches Dermatologioues Galderma (C.I.R.D. Galderma)
    Inventors: Laszlo Fesus, Zsuzsa Szondy, Uwe Reichert
  • Use of a RAR-gamma-specific agonist ligand for increasing the rate of apoptosis
    Publication number: 20030092758
    Abstract: The present invention relates to the use of at least one RAR receptor agonist ligand, particularly 6-[3-(adamantan-1-yl)-4-(prop-2-ynyloxy)phenyl]naphthalene-2-carboxylic acid or 5-[(E)-3-oxo-3-(5,5,8,8-tetrahydronaphthalene-2-yl)propenyl]thiophene-2-carboxylic acid, to prepare a pharmaceutical composition for increasing the rate of apoptosis in at least one cell population in which apoptosis may be induced by activating RAR-&ggr; receptors. The composition is particularly useful for treating a disease or disorder related to an insufficient rate of apoptosis in at least one cell population in which apoptosis may be induced by activating RAR-&ggr; receptors.
    Type: Application
    Filed: June 28, 2002
    Publication date: May 15, 2003
    Inventors: Laszlo Fesus, Zsuzsa Szondy, Uwe Reichert
  • Use of a RAR-&ggr;-specific agonist ligand for increasing the rate of apoptosis
    Patent number: 6506796
    Abstract: Methods of cosmetically or therapeutically treating diseases or disorders in cell populations whose pathology is linked to an inadequate rate of apoptosis by administering a therapeutically effective amount of 6-3-(1-adamantyl)-4-hydroxyphenyl)-2-naphthanoic acid.
    Type: Grant
    Filed: July 25, 2000
    Date of Patent: January 14, 2003
    Assignee: Centre International de Recherches Dermatologiques Galderma
    Inventors: Laszlo Fesus, Zsuzsa Szondy, Uwe Reichert
  • Use of a RAR-gamma-specific agonist ligand for increasing the rate of apoptosis
    Publication number: 20010018456
    Abstract: A method for increasing the rate of apoptosis in at least one cell population in which apoptosis is induced by activating receptors of the RAR-&ggr; type, the method comprising exposing the cell population to an effective amount of at least one agonist ligand which is specific for receptors of the RAR-&ggr; type to increase the rate of apoptosis.
    Type: Application
    Filed: March 9, 2001
    Publication date: August 30, 2001
    Inventors: Laszlo Fesus, Zsuzsa Szondy, Uwe Reichert
  • .gamma.-RAR antagonist ligand or .alpha.-RAR agonist ligand as an apoptosis inhibitor
    Patent number: 6063797
    Abstract: The use of a combination of an alpha RAR receptor-specific agonist ligand and a gamma RAR receptor-specific antagonist ligand to reduce the rate of apoptosis is disclosed.
    Type: Grant
    Filed: July 15, 1998
    Date of Patent: May 16, 2000
    Assignee: C.I.R.D. Galderma
    Inventors: Laszlo Fesus, Zsuzsa Szondy, Uwe Reichert