Patents by Inventor Zsuzsanna M. I. Kovacs

Zsuzsanna M. I. Kovacs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
    Patent number: 5215971
    Abstract: Use of a compound of the formula ##STR1## wherein A is .beta.-2'-deoxy-D-ribofuranosyl or .beta.-D-arabinofuranosyl;R.sup.1 is hydroxy or amino;R.sup.2 is cycloalkyl or alkyl-substituted cycloalkyl containing 1-5 carbon atoms; saturated or unsaturated, straight or branched alkyl containing 1-5 carbon atoms which may be unsubstituted or substituted with halogen, hydroxy, mercapto, trifluoroalkyl or difluoroalkyl containing 1-3 carbon atoms, phenoxy or alkoxy containing 1-3 carbon atoms; phenyl or phenylalkyl containing 1-3 carbon atoms in the alkyl part, or a physiologically acceptable salt thereof,for manufacture of a medicament for therapeutic or prophylactic control or treatment of retrovirus, especially HIV, or hepatitis B virus infections in animal and man and to a method of such treatment.
    Type: Grant
    Filed: July 2, 1991
    Date of Patent: June 1, 1993
    Assignee: Medivir AB
    Inventors: Roelf Datema, Kristina B. Gotthammar, Karl N. G. Johansson, Zsuzsanna M. I. Kovacs, Bjorn G. Lindborg, Goran B. Stening, Bo F. berg
  • Derivatives of purine
    Patent number: 5036071
    Abstract: Antivirally active compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or hydroxymethyl;R.sub.2 is hydrogen, hydroxy or hydroxymethyl;R.sub.3 is hydrogen; or R.sub.1 and R.sub.3 together constitute an additional carbon-carbon bond;with the proviso that when R.sub.1 is hydrogen then R.sub.2 is hydroxy or hydroxymethyl, that when R.sub.1 is hydroxymethyl then R.sub.2 is hydrogen and that when R.sub.2 is hydroxy then R.sub.1 is hydrogen; and physiologically acceptable salts; geometric or optical isomers thereof; processes for preparation of said compounds, pharmaceutical preparations containing the compounds, methods for treatment of virus infections and medical use of the compounds.
    Type: Grant
    Filed: January 22, 1988
    Date of Patent: July 30, 1991
    Assignee: Medivir AB
    Inventors: Karl N. G. Johansson, Zsuzsanna M. I. Kovacs, Bjorn G. Lindborg, Goran B. Stening
  • Derivatives of guanine for combating herpes virus infections
    Patent number: 4495190
    Abstract: Novel antiviral compounds of the formula ##STR1## wherein each of R.sub.1 and R.sub.2, which are the same or different is hydrogen, hydroxy or fluoro; provided that R.sub.1 or R.sub.2 is hydrogen when R.sub.1 and R.sub.2 are different, and provided that R.sub.1 and R.sub.2 are hydroxy or fluoro when R.sub.1 and R.sub.2 are the same; or a physiologically acceptable salt or an optical isomer thereof, methods for their preparation, pharmaceutical preparations containing the compounds, and methods for the treatment of virus infections and other diseases caused by viruses.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: January 22, 1985
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Curt-Erik Hagberg, Karl N. Johansson, Zsuzsanna M. I. Kovacs, Goran B. Stening