Patents by Inventor Zulma Gazit

Zulma Gazit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160081578
    Abstract: The present invention teaches novel methods of diagnosing and prognosing conditions associated with tissue degeneration and/or pain, including intervertebral disc degeneration, discogenic pain, osteoarthritis, rheumatoid arthritis, and articular cartilage injury. Using the inventive noninvasive imaging methods, the diagnosis and prognosis of back pain and related conditions can be quickly and accurately determined by detecting one or more biomarkers disclosed herein.
    Type: Application
    Filed: April 18, 2014
    Publication date: March 24, 2016
    Applicant: Cedars-Sinai Medical Center
    Inventors: Dan Gazit, Debiao Li, Hyun Bae, Gadi Pelled, Zulma Gazit, Qi Liu, Wafa Tawackoli
  • Publication number: 20150159191
    Abstract: A system for qualifying cells of a cell sample labeled with a magnetic or magnetizable moiety is provided. The system includes a cell sample holder for holding a cell of the cells and a first cell analyzer which includes a magnetic field source for applying a magnetic field to the cell and a sensor for qualifying and/or quantifying an effect of the magnetic field on the cell.
    Type: Application
    Filed: January 6, 2015
    Publication date: June 11, 2015
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Dan GAZIT, Boris RUBINSKY, Gadi PELLED, Zulma GAZIT
  • Publication number: 20120082704
    Abstract: An improved composition for inducing bone growth is provided that is a combination of at least DBM and an oxygen carrier. Injection/implantation of a composition of DBM and an oxygen carrier (e.g. a perfluorocarbon) results in enhancement of bone formation compared to DBM alone.
    Type: Application
    Filed: October 4, 2011
    Publication date: April 5, 2012
    Inventors: Frank M. Phillips, Stephen H. Hochschuler, Dan Gazit, Gadi Pelled, Zulma Gazit
  • Publication number: 20120078163
    Abstract: A method of generating bone or connective tissue in a subject in need thereof, the method comprising: (a) implanting a scaffold in a damaged region of the subject, the scaffold comprising a tissue growth promoting agent; and (b) enhancing uptake of the tissue growth promoting agent into cells located on the scaffold, wherein the enhancing is effected by induced poration of the cells thereby generating bone or connective tissue in the subject. Kits for generating bone or connective tissue are also provided.
    Type: Application
    Filed: May 27, 2010
    Publication date: March 29, 2012
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Dan Gazit, Gadi Pelled, Zulma Gazit, Nadav Kimelman-Bleich
  • Patent number: 8142773
    Abstract: The invention relates to methods of isolating and implanting mesenchymal stem cells for tissue repair or formation, without prior culture expansion of the mesenchymal stem cells. In particular, the invention relates to methods of isolating mesenchymal stem cells from bone marrow, for repairing or inducing formation of bone, without prior culture expansion of the mesenchymal stem cells. The invention further relates to an isolated, non-culturally expanded human adult mesenchymal stem cell population.
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: March 27, 2012
    Assignee: Yissum Research Development Company of the hebrew University of Jerusalem
    Inventors: Hadi Aslan, Dan Gazit, Zulma Gazit
  • Publication number: 20110217730
    Abstract: A system for qualifying cells of a cell sample labeled with a magnetic or magnetizable moiety is provided. The system includes a cell sample holder for holding a cell of the cells and a first cell analyzer which includes a magnetic field source for applying a magnetic field to the cell and a sensor for qualifying and/or quantifying an effect of the magnetic field on the cell.
    Type: Application
    Filed: May 16, 2011
    Publication date: September 8, 2011
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Dan Gazit, Boris Rubinsky, Gadi Pelled, Zulma Gazit
  • Patent number: 7951582
    Abstract: A system for qualifying cells of a cell sample labeled with a magnetic or magnetizable moiety is provided. The system includes a cell sample holder for holding a cell of the cells and a first cell analyzer which includes a magnetic field source for applying a magnetic field to the cell and a sensor for qualifying and/or quantifying an effect of the magnetic field on the cell.
    Type: Grant
    Filed: November 6, 2006
    Date of Patent: May 31, 2011
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Dan Gazit, Boris Rubinsky, Gadi Pelled, Zulma Gazit
  • Publication number: 20090214649
    Abstract: Provided are fibrin or silk matrices comprising an oxygen carrier, and matrices, which comprise an oxygen carrier and mesenchymal stem cells. Also provided are methods of generating and using same for ex vivo or in vivo tissue regeneration and/or repair such as for treating a non-union bone fracture and a condition requiring spinal fusion.
    Type: Application
    Filed: January 29, 2009
    Publication date: August 27, 2009
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Dan Gazit, Gadi Pelled, Zulma Gazit, Nadav Kimelman-Bleich
  • Publication number: 20090029407
    Abstract: A system for qualifying cells of a cell sample labeled with a magnetic or magnetizable moiety is provided. The system includes a cell sample holder for holding a cell of the cells and a first cell analyzer which includes a magnetic field source for applying a magnetic field to the cell and a sensor for qualifying and/or quantifying an effect of the magnetic field on the cell.
    Type: Application
    Filed: November 6, 2006
    Publication date: January 29, 2009
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Dan Gazit, Boris Rubinsky, Gadi Pelled, Zulma Gazit
  • Publication number: 20080112936
    Abstract: The invention relates to methods of isolating and implanting mesenchymal stem cells for tissue repair or formation, without prior culture expansion of the mesenchymal stem cells. In particular, the invention relates to methods of isolating mesenchymal stem cells from bone marrow, for repairing or inducing formation of bone, without prior culture expansion of the mesenchymal stem cells. The invention further relates to an isolated, non-culurally expanded human adult mesenchymal stem cell population.
    Type: Application
    Filed: January 17, 2008
    Publication date: May 15, 2008
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Hadi Aslan, Dan Gazit, Zulma Gazit
  • Publication number: 20050249731
    Abstract: The invention relates to methods of isolating and implanting mesenchymal stem cells for tissue repair or formation, without prior culture expansion of the mesenchymal stem cells. In particular, the invention relates to methods of isolating mesenchymal stem cells from bone marrow, for repairing or inducing formation of bone, without prior culture expansion of the mesenchymal stem cells. The invention further relates to an isolated, non-culurally expanded human adult mesenchymal stem cell population.
    Type: Application
    Filed: July 15, 2003
    Publication date: November 10, 2005
    Inventors: Hadi Aslan, Dan Gazit, Zulma Gazit