Abstract: The present disclosure relates to antibodies, in particular monoclonal antibodies of murine, chimeric, and humanized origin, that specifically bind to the human TROP2 protein, and to the amino acid and nucleotide sequences encoding these antibodies. The disclosure also discloses the use of these antibodies as a diagnostic reagent or a drug in the diagnostic and/or therapeutic management of malignancies or any lesion related to the overexpression of said receptor.

Abstract: Methods and systems are provided for a heat exchanger for a motorized vehicle. In one example, a heat exchanger includes a plurality of tubes coupled to a header, with each tube including a partition extending a height of the tube. The partition includes a notch positioned at an end of the tube coupled to the header, with the notch extending into the tube.

Abstract: A vehicle system is provided. The system may include a first coolant loop, including a radiator, a second coolant loop including a battery chiller, and a centrifugal coolant separator. The centrifugal coolant separator may include a frustoconical hollow body having a base defining a drain and a ceiling defining a spout, and a pair of coolant lines arranged orthogonal to and on opposite sides of the body such that coolant exiting the lines travels along the inner surface and collects at the base to separate gas from the coolant, wherein the spout vents the gas and the coolant exits the drain.

Abstract: Methods and systems are provided for a heat exchanger for a motorized vehicle. In one example, a heat exchanger includes a plurality of tubes coupled to a header, with each tube including a partition extending a height of the tube. The partition includes a notch positioned at an end of the tube coupled to the header, with the notch extending into the tube.

Abstract: A vehicle system is provided. The system may include a first coolant loop, including a radiator, a second coolant loop including a battery chiller, and a centrifugal coolant separator. The centrifugal coolant separator may include a frustoconical hollow body having a base defining a drain and a ceiling defining a spout, and a pair of coolant lines arranged orthogonal to and on opposite sides of the body such that coolant exiting the lines travels along the inner surface and collects at the base to separate gas from the coolant, wherein the spout vents the gas and the coolant exits the drain.