Patents by Inventor Zuoying DUAN

Zuoying DUAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of genomic NW_006882077.1 in CHO cell for stably expressing a protein
    Patent number: 11732276
    Abstract: Use of genomic NW_006882077.1 in CHO cell for stably expressing a protein is disclosed. The certain site in CHO cell genome for stably expressing a protein is positioned at a base of No. 691045 in a CHO cell gene NW_006882077.1; a sequence of 5? NNNNNNNNNNNNNNNNNNNNNGG3? that can be identified by CRISPR/Cas9 technology and positioned in a base range of No. 690980-691090 around the certain site is a target sequence. Various of protein genes are introduced into a fixed site in CHO cell genome, and expressed stably in the present disclosure.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: August 22, 2023
    Assignee: Jiangnan University
    Inventors: Huazhong Li, Yun Chen, Jian Jin, Songtao Zhou, Zuoying Duan, Xiaohai Gong
  • Use of genomic NW_006880285.1 in CHO cell for stably expressing a protein
    Patent number: 11692204
    Abstract: Use of genomic NW_006880285.1 in CHO cell for stably expressing a protein is disclosed. The certain site in CHO cell genome for stably expressing a protein is positioned at a base of No. 1235357 in a CHO cell gene NW_006880285.1; a sequence of 5? NNNNNNNNNNNNNNNNNNNNNGG3? that can be identified by CRISPR/Cas9 technology and positioned in a base range of No. 1235284-1235429 around the certain site is a target sequence. Various of protein genes are introduced into a fixed site in CHO cell genome, and expressed stably in the present disclosure.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: July 4, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Jian Jin, Yun Chen, Huazhong Li, Songtao Zhou, Zuoying Duan, Xiaohai Gong
  • USE OF NW_006883358.1 IN CHO CELL GENOME FOR STABLE EXPRESSION OF PROTEIN
    Publication number: 20220002754
    Abstract: The invention provides use of NW_006883358.1 in a CHO cell genome for stable expression of a protein. A site for stable expression of a protein in the CHO cell genome is located at the 6874389th base of CHO cell gene NW_006883358.1; 5?NNNNNNNNNNNNNNNNNNNNNGG3? within a range of 6874325-6874443 near the site, which can be identified by CRISPR/Cas9 technology, is a target sequence. In the present application, different protein genes are introduced to a fixed position in the CHO cell genome for stable expression.
    Type: Application
    Filed: October 22, 2019
    Publication date: January 6, 2022
    Inventors: Yun CHEN, Jian JIN, Huazhong LI, Songtao ZHOU, Zuoying DUAN, Xiaohai GONG
  • USE OF GENOMIC NW_006882077.1 IN CHO CELL FOR STABLY EXPRESSING A PROTEIN
    Publication number: 20210238634
    Abstract: Use of genomic NW_006882077.1 in CHO cell for stably expressing a protein is disclosed. The certain site in CHO cell genome for stably expressing a protein is positioned at a base of No. 691045 in a CHO cell gene NW_006882077.1; a sequence of 5? NNNNNNNNNNNNNNNNNNNNNGG3? that can be identified by CRISPR/Cas9 technology and positioned in a base range of No. 690980-691090 around the certain site is a target sequence. Various of protein genes are introduced into a fixed site in CHO cell genome, and expressed stably in the present disclosure.
    Type: Application
    Filed: December 3, 2018
    Publication date: August 5, 2021
    Applicant: Jiangnan University
    Inventors: Huazhong LI, Jian JIN, Songtao ZHOU, Yun CHEN, Zuoying DUAN, Xiaohai GONG
  • USE OF GENOMIC NW_006880285.1 IN CHO CELL FOR STABLY EXPRESSING A PROTEIN
    Publication number: 20210222202
    Abstract: Use of genomic NW_006880285.1 in CHO cell for stably expressing a protein is disclosed. The certain site in CHO cell genome for stably expressing a protein is positioned at a base of No. 1235357 in a CHO cell gene NW_006880285.1; a sequence of 5? NNNNNNNNNNNNNNNNNNNNNGG3? that can be identified by CRISPR/Cas9 technology and positioned in a base range of No. 1235284-1235429 around the certain site is a target sequence. Various of protein genes are introduced into a fixed site in CHO cell genome, and expressed stably in the present disclosure.
    Type: Application
    Filed: December 3, 2018
    Publication date: July 22, 2021
    Applicant: Jiangnan University
    Inventors: Jian JIN, Huazhong LI, Songtao ZHOU, Yun CHEN, Zuoying DUAN, Xiaohai GONG