Patents by Inventor Zurit Levine

Zurit Levine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Variants of alternative splicing
    Publication number: 20050281810
    Abstract: The present invention concerns novel variants produced by alternative splicing of known genes, amino acid sequences of the variants as well as their uses in detection and therapy.
    Type: Application
    Filed: March 31, 2005
    Publication date: December 22, 2005
    Inventors: Jeanne Bernstein, Zurit Levine
  • Novel brain natriuretic peptide variants and methods of use thereof
    Publication number: 20050277156
    Abstract: Novel BNP variants. The novel BNP variants according to the present invention may optionally be used for diagnosis of a BNP variant-detectable disease as described herein.
    Type: Application
    Filed: January 27, 2005
    Publication date: December 15, 2005
    Inventors: Gad Cojocaru, Alexander Diber, Amit Novik, Sarah Pollock, Zurit Levine, Yossi Cohen, Michal Ayalon-Soffer
  • Variants of protein kinases
    Patent number: 6936450
    Abstract: The present invention concerns nucleic acid sequences and amino acid sequences of dominant negative variants of kinases, i.e. of sequences which inhibit activity of kinases in a dominant manner. The invention also concerns pharmaceutical compositions and detection methods using these sequences.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: August 30, 2005
    Assignee: Compugen Ltd.
    Inventors: Zurit Levine, Jeanne Bernstein
  • Methods and systems for identifying naturally occurring antisense transcripts and methods, kits and arrays utilizing same
    Publication number: 20050009771
    Abstract: A method of identifying putative naturally occurring antisense transcripts is provided. The method is effected by (a) computationally aligning a first database including sense-oriented polynucleotide sequences with a second database including expressed polynucleotide sequences; and (b) identifying expressed polynucleotide sequences from the second database being capable of forming a duplex with at least one sense-oriented polynucleotide sequence of the first database, thereby identifying putative naturally occurring antisense transcripts. Also provided are polynucleotides and polypeptide sequences identified by the above-described methodology.
    Type: Application
    Filed: January 27, 2004
    Publication date: January 13, 2005
    Inventors: Erez Levanon, Jeanne Bernstein, Sarah Pollock, Alex Diber, Zurit Levine, Sergey Nemzer, Vladimir Grebinsky, Hanqing Xie, Brian Meloon, Andrew Olson, Dvir Dahary, Yossi Cohen, Avi Shoshan, Shira Walach, Alon Wasserman, Rami Khosravi, Galit Rotman
  • Novel polynucleotides encoding soluble polypeptides and methods using same
    Publication number: 20040248157
    Abstract: An isolated polynucleotide is provided. The isolated polynucleotide comprising a nucleic acid sequence encoding a polypeptide having an amino acid sequence at least 70% identical to SEQ ID NO: 1, as determined using the LALIGN software of EMBnet Switzerland (http://www.ch.embnet.org/index.
    Type: Application
    Filed: January 27, 2004
    Publication date: December 9, 2004
    Inventors: Michal Ayalon-Soffer, Sarah Pollock, Alex Diber, Zurit Levine, Sergey Nemzer, Dvir Dahary, Rotem Sorek, Erez Levanon, Galit Rotman, Kinneret Savitsky, Chen Chermesh, Liat Mintz, Shiri Freilich, Nili Beck, Wei-Yong Zhu, Alon Wasserman, Idit Azar, Jeanne Bernstein
  • Methods and systems for identifying naturally occurring antisense transcripts and methods, kits and arrays utilizing same
    Publication number: 20030228618
    Abstract: A method of identifying putative naturally occurring antisense transcripts is provided. The method is effected by (a) computationally aligning a first database including sense-oriented polynucleotide sequences with a second database including expressed polynucleotide sequences; and (b) identifying expressed polynucleotide sequences from the second database being capable of forming a duplex with at least one sense-oriented polynucleotide sequence of the first database, thereby identifying putative naturally occurring antisense transcripts.
    Type: Application
    Filed: May 20, 2003
    Publication date: December 11, 2003
    Inventors: Erez Levanon, Sarah Pollock, Sergey Nemzer, Avi Shoshan, Rami Khosravi, Shira Walach, Zurit Levine, Jeanne Bernstein, Dvir Dahari, Alon Wasserman, Galit Rotman
  • PI3K - regulatory subunit homology
    Publication number: 20030125288
    Abstract: The invention concerns novel nucleic acid and amino acid sequences which are homologs of the PI3K-regulatory subunits. The invention also concerns pharmaceutical compositions containing these sequences as well as methods of detection using the sequences.
    Type: Application
    Filed: September 30, 2002
    Publication date: July 3, 2003
    Inventors: Idit Azar, Zurit Levine, Jeanne Bernstein, Kinneret Savitzky
  • Variants of protein kinases
    Publication number: 20020110811
    Abstract: The present invention concerns nucleic acid sequences and amino acid sequences of dominant negative variants of kinases, i.e. of sequences which inhibit activity of kinases in a dominant manner. The invention also concerns pharmaceutical compositions and detection methods using these sequences.
    Type: Application
    Filed: January 26, 2001
    Publication date: August 15, 2002
    Applicant: Compugen Ltd.
    Inventors: Zurit Levine, Jeanne Bernstein
  • Splice variants of oncogenes
    Publication number: 20020086384
    Abstract: The present invention concerns a plurality of variant nucleic acid and amino acid sequences obtained by alternative splicing of known genes which have been reported in the literature as being involved with tumors. The present invention further concerns a method for detecting said nucleic acid and amino acid sequences, for example, for diagnostic purposes, especially for detection of cancer, predisposition to cancer or evaluation of cancer state.
    Type: Application
    Filed: March 13, 2001
    Publication date: July 4, 2002
    Inventors: Zurit Levine, Anat David, Cobby Romano, Jeanne Bernstein