Patents by Inventor Zvi Granot

Zvi Granot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neutrophil-binding peptides
    Patent number: 11952431
    Abstract: Disclosed are peptides that specifically bind to neutrophils and uses thereof for neutrophil-targeted delivery of drugs or diagnostic agents in medical conditions including cancer as well as infectious, inflammatory and autoimmune diseases or disorders.
    Type: Grant
    Filed: December 27, 2022
    Date of Patent: April 9, 2024
    Assignees: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., HADASIT MEIDCAL RESEARCH SERVICES & DEVELOPMENT LTD.
    Inventors: Zvika Granot, Zvi Gregorio Fridlender, Sandra Vols
  • Use of entrained neutrophils to treat metastatic and micrometastatic disease in at risk patients
    Patent number: 9199028
    Abstract: The present invention relates generally to compositions and methods for treating cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis by combating metastasis and abrogating chemoresistance in cancer cells. In particular, the invention relates to the role of white blood cells, i.e. neutrophils and neutrophil-like cells, in preventing the spread of cancer from a primary tumor to secondary locations in the body. The invention provides methods for reducing or delaying the spread of metastatic cancer cells in a patient at risk for metastatic tumor development, at risk for metastatic relapse, i.e. prophylactic methods, and treating patients suffering from metastatic tumors.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: December 1, 2015
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Zvi Granot, Robert Benezra
  • USE OF ENTRAINED NEUTROPHILS TO TREAT METASTATIC AND MICROMETASTATIC DISEASE IN AT RISK PATIENTS
    Publication number: 20130072844
    Abstract: The present invention relates generally to compositions and methods for treating cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis by combating metastasis and abrogating chemoresistance in cancer cells. In particular, the invention relates to the role of white blood cells, i.e. neutrophils and neutrophil-like cells, in preventing the spread of cancer from a primary tumor to secondary locations in the body. The invention provides methods for reducing or delaying the spread of metastatic cancer cells in a patient at risk for metastatic tumor development, at risk for metastatic relapse, i.e. prophylactic methods, and treating patients suffering from metastatic tumors.
    Type: Application
    Filed: January 14, 2011
    Publication date: March 21, 2013
    Inventors: Zvi Granot, Robert Benezra