Patents by Inventor Zvi Israel
Zvi Israel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220151537Abstract: A brain navigation device, comprising: a lead with an elongated lead body; at least one macro-electrode contact positioned on an outer surface on the lead; wherein the at least one macro-electrode contact is located at the distal part of said lead; and wherein the at least one macro-electrode contact is configured to be used during lead navigation.Type: ApplicationFiled: January 31, 2022Publication date: May 19, 2022Applicant: Alpha Omega Engineering Ltd.Inventors: Omer NAOR, Adi BALAN, Hagai BERGMAN, Imad YOUNIS, Oren A. GARGIR, Zvi ISRAEL, Jubran ELFAR, Paul MCSHERRY, Steven SCOTT, Benjamin MATTER
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Patent number: 11234632Abstract: A brain navigation device, comprising a lead with an elongated lead body, at least one macro-electrode contact positioned on an outer surface on the lead, wherein the at least one macro-electrode contact is located at the distal part of the lead, and wherein the at least one macro-electrode contact is configured to be used during lead navigation.Type: GrantFiled: March 14, 2017Date of Patent: February 1, 2022Assignee: Alpha Omega Engineering Ltd.Inventors: Omer Naor, Adi Balan, Hagai Bergman, Imad Younis, Oren A. Gargir, Zvi Israel, Jubran Elfar, Paul Mcsherry, Steven Scott, Benjamin Matter
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Publication number: 20210282869Abstract: A system for differential recording connectable to an electrical lead with at least two electrodes, including: the lead having a distal end; at least one amplifier electrically connectable to the at least two electrodes, wherein the at least one amplifier subtracts a signal recorded by one of the at least two electrodes, from a signal recorded by the other one of the at least two electrodes to generate a differential signal; a memory configured for storing said differential signal and reference indications of electrical signals associated with neural tissue; a processing circuitry for detection of an anatomical position, wherein the processing circuitry calculates an anatomical position of the electrical lead based on processing of the differential signal and the reference indications of electrical signals associated with the neural tissue.Type: ApplicationFiled: May 26, 2021Publication date: September 16, 2021Applicant: Alpha Omega Engineering Ltd.Inventors: Hagai BERGMAN, Omer NAOR, Jubran ELFAR, Imad YOUNIS, Adi BALAN, Zvi ISRAEL, Dan VALSKY, Odeya MARMOR, Renana EITAN, John RIZIK, Majd SLEEM, Paul MCSHERRY, Steven SCOTT, Benjamin MATTER
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Patent number: 11051889Abstract: A system for differential recording connectable to an electrical lead with at least two electrodes, including: the lead having a distal end; at least one amplifier electrically connectable to the at least two electrodes, wherein the at least one amplifier subtracts a signal recorded by one of the at least two electrodes, from a signal recorded by the other one of the at least two electrodes to generate a differential signal; a memory configured for storing said differential signal and reference indications of electrical signals associated with neural tissue; a processing circuitry for detection of an anatomical position, wherein the processing circuitry calculates an anatomical position of the electrical lead based on processing of the differential signal and the reference indications of electrical signals associated with the neural tissue.Type: GrantFiled: July 7, 2017Date of Patent: July 6, 2021Assignee: Alpha Omega Engineering Ltd.Inventors: Hagai Bergman, Omer Naor, Jubran Elfar, Imad Younis, Adi Balan, Zvi Israel, Dan Valsky, Odeya Marmor, Renana Eitan, John Rizik, Majd Sleem, Paul McSherry, Steven Scott, Benjamin Matter
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Patent number: 10932862Abstract: The disclosure relates to an automatic brain-probe guidance systems. Specifically, the disclosure is directed to a real-time method and system for guiding a probe to the dorsolateral oscillatory region of the subthalamic nucleus in the brain of a subject in need thereof using factored Partially Observable Markov Decision Process (POMDP) via Hidden Markov Model (HMM) represented as a dynamic Bayesian Network (DBN).Type: GrantFiled: May 9, 2016Date of Patent: March 2, 2021Assignee: Alpha Omega Neuro Technologies Ltd.Inventors: Majid Mechael, Dan Valsky, Hagai Bergman, Zvi Israel
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Publication number: 20190321106Abstract: A system for differential recording connectable to an electrical lead with at least two electrodes, including: the lead having a distal end; at least one amplifier electrically connectable to the at least two electrodes, wherein the at least one amplifier subtracts a signal recorded by one of the at least two electrodes, from a signal recorded by the other one of the at least two electrodes to generate a differential signal; a memory configured for storing said differential signal and reference indications of electrical signals associated with neural tissue; a processing circuitry for detection of an anatomical position, wherein the processing circuitry calculates an anatomical position of the electrical lead based on processing of the differential signal and the reference indications of electrical signals associated with the neural tissue.Type: ApplicationFiled: July 7, 2017Publication date: October 24, 2019Applicant: Alpha Omega Neuro Technologies Ltd.Inventors: Hagai BERGMAN, Omer NAOR, Jubran ELFAR, Imad YOUNIS, Adi BALAN, Zvi ISRAEL, Dan VALSKY, Odeya MARMOR, Renana EITAN, John RIZIK, Majd SLEEM, Paul MCSHERRY, Steven SCOTT, Benjamin MATTER
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Publication number: 20190069797Abstract: A brain navigation device, comprising: a lead with an elongated lead body; at least one macro-electrode contact positioned on an outer surface on the lead; wherein the at least one macro-electrode contact is located at the distal part of said lead; and wherein the at least one macro-electrode contact is configured to be used during lead navigation.Type: ApplicationFiled: March 14, 2017Publication date: March 7, 2019Applicant: Alpha Omega Neuro Technologies Ltd.Inventors: Omer NAOR, Adi BALAN, Hagai BERGMAN, Imad YOUNIS, Oren A. GARGIR, Zvi ISRAEL, Jubran ELFAR, Paul MCSHERRY, Steven SCOTT, Benjamin MATTER
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Publication number: 20180125585Abstract: The disclosure relates to an automatic brain-probe guidance systems. Specifically, the disclosure is directed to a real-time method and system for guiding a probe to the dorsolateral oscillatory region of the subthalamic nucleus in the brain of a subject in need thereof using factored Partially Observable Markov Decision Process (POMDP) via Hidden Markov Model (HMM) represented as a dynamic Bayesian Network (DBN).Type: ApplicationFiled: May 9, 2016Publication date: May 10, 2018Inventors: Majid MECHAEL, Dan VALSKY, Hagai BERGMAN, Zvi ISRAEL
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Patent number: 8792972Abstract: A real-time method and system to accurately demarcate sub-territories of the subthalamic nucleus area in the brain during surgery, based on microelectrode recordings and a Hidden Markov Model. Root mean square and power spectral density of the microelectrode recordings are used to train and test Hidden Markov Model in identifying the dorsolateral oscillatory region and non-oscillatory sub-territories within the subthalamic nucleus. After the dorsolateral oscillatory region in the subthalamic nucleus is mapped, the microelectrodes are removed, and a macroelectrode is inserted in the mapped dorsolateral oscillatory region for producing deep brain simulation for treatment of Parkinson's disease.Type: GrantFiled: February 5, 2010Date of Patent: July 29, 2014Assignee: Alpha Omega Engineering Ltd.Inventors: Adam Zaidel, Hagai Bergman, Zvi Israel
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Publication number: 20100241020Abstract: A real-time method and system to accurately demarcate sub-territories of the subthalamic nucleus area in the brain during surgery, based on microelectrode recordings and a Hidden Markov Model. Root mean square and power spectral density of the microelectrode recordings are used to train and test Hidden Markov Model in identifying the dorsolateral oscillatory region and non-oscillatory sub-territories within the subthalamic nucleus. After the dorsolateral oscillatory region in the subthalamic nucleus is mapped, the microelectrodes are removed, and a macroelectrode is inserted in the mapped dorsolateral oscillatory region for producing deep brain simulation for treatment of Parkinson's disease.Type: ApplicationFiled: February 5, 2010Publication date: September 23, 2010Applicants: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD.Inventors: Adam Zaidel, Hagai Bergman, Zvi Israel