Abstract: The present invention provides a device for connection of a biological structure with at least one other structure, the device including a first tubular member and a second tubular member and at least one arm for connecting the first tubular member to the second tubular member. The first tubular member includes a first opening at a proximal extremity of the tubular member, a second opening at a distal extremity of the tubular member and a central cavity within the body of the tubular member for accommodating the biological structure. The second tubular member includes a first opening at a proximal extremity of the tubular member, a second opening at a distal extremity of the tubular member and a central cavity within the body of the tubular member. The present invention further provides methods of connecting one or more structures, such as biological structures and grafts.

Abstract: The present invention provides devices for connecting biological structures. The device features a tubular member that includes a tubular body. The tubular member may include a plurality of interwoven lengths configured for reversible radial enlargement and reversible radial contraction of the tubular member. In some aspects the tubular member may include a net design of interconnected cells configured for reversible radial enlargement of the tubular member. The tubular member includes a distal opening, a proximal opening, a central cavity within the tubular member for receiving and retaining a biological structure and a plurality of spaced apart protrusions protruding out from the exterior surface of the body of the device for fixing to the device an end of the biological structure and for fixing a second structure to the device to facilitate connecting the biological structure to the second structure.

Abstract: The present invention provides a device for connecting at least one biological structure, the device including a tubular member, a first opening at one end of the member, a second opening at a second opposing end of the member and a central cavity within the member for accommodating the at least one biological structure. The member includes a plurality of interwoven lengths configured for reversible radial enlargement of the member when the extremities are pushed inwards and reversible radial contraction of the member when the extremities are pulled outwards. The present invention further provides methods of connecting one or more biological structures.

Abstract: The present invention provides a device for connecting at least one biological structure, the device including a tubular member, a first opening at one end of the member, a second opening at a second opposing end of the member and a central cavity within the member for accommodating the at least one biological structure. The member includes a plurality of interwoven lengths configured for reversible radial enlargement of the member when the extremities are pushed inwards and reversible radial contraction of the member when the extremities are pulled outwards. The present invention further provides methods of connecting one or more biological structures.

Abstract: An RFID device including: electronic circuitry suitable for an RFID device comprising a radio frequency section; an antenna; a battery which provides the device with power; and at least one quarter wavelength transmission line coupled between the battery and one or both of the electronic circuitry and the antenna.

Abstract: An apparatus for dermal treatment of an active substance having certain physical properties having a flexible, wearable patch conformable to the contour of a skin surface and having: a first electrode adapted to communicate the active substance into the skin by application of an electrical current on the skin surface, a second electrode capable of closing an electrical circuit with the skin surface, a power source for providing a current and voltage connected through a conductive media to the first and second electrode, and an apparatus for substantially controlling penetration depth of the active substance by selecting at least one variable from a plurality of variables.

Abstract: The present invention provides a device and kit and method of use thereof for wound treatment of a subject. The device may include an electrically operated patch or other means of delivery of electrical current and a connected moist surface. Optionally, the device may include a composition comprising an active substance useful in wound treatment. Preferably, the means of delivery of electrical current includes a power source and a plurality of electrodes disposed in a suitable conformation on a base substrate layer, which readily facilitates electrical contact with the body area of the subject. Preferably, the kit may include a means of delivery of electrical current and a moist surface provided as separate components. The present invention further provides a thin and flexible device for galvanic treatment to treat wounds with electrical stimulation. Preferably, the device is made using a printing technique.

Abstract: The present invention provides an intermediate attachment mechanism, called a powerposer (10), which includes at least one power source (16) coupled to an integrated circuit (14), at least one integrated circuit, which is arranged to store a code comprising information and powered with energy provided by the power source and a substrate (12) on which the at least one power source and the at least one integrated circuit are disposed, and wherein the substrate comprises connection means (22) for connecting to an application device and attachment means for attaching to the application device. Further, the present invention provides a battery assisted or active RFID transponder featuring a transponder substrate, at least one antenna disposed on the transponder substrate and a powerposer disposed on the transponder substrate. Still further the present invention provides methods of production of a powerposer and an active or battery assisted RFID transponder comprising a powerposer.

Abstract: A method of forming an electrochemical cell is disclosed. The method comprises contacting a negative pole layer and a positive pole layer one with the other or with an optional layer interposed therebetween. The pole layers and the optional layer therebetween are selected to self-form an interfacial separator layer between the pole layers upon such contacting.

Abstract: A radio frequency identification (RFID) transponder comprising: an antenna comprising at least two connected dipoles, and having an input port feeding one of the dipoles; a conductive ground plane separated by a predetermined distance from the antenna by a dielectric; and a transponder electrically connected to the input port and operative to produce a response signal when the transponder receives a signal at a given frequency from the antenna.

Abstract: The present invention provides a powered treatment device comprising at least one power source for supplying electrical energy to the device, and wherein at least one component of the power source is also configured as a power source treatment device electrode to facilitate electrical contact with a body region. In an embodiment wherein one component of the power source is configured as a power source treatment device electrode, the powered treatment device may further comprise at least one non-power source device electrode of opposite polarity from the power source treatment device electrode, wherein the at least one non-power source device electrode is electrically coupled to the at least one power source to facilitate electrical contact with a body area.

Abstract: Methods, apparatus, and kits for onychomycosis treatment are presented. In one embodiment, a kit for treatment includes an anti-fungal agent, in a composition, and an electrically powered patch. Exemplary embodiments of the patch include a first electrode, a power source having a first and second terminal, a second electrode coupled to the second terminal of the power source, and a base member supporting the first electrode, the second electrode, and the power source. Embodiments include those where the first and second electrode and power source are printed on the base member. Anti-fungal agents may be unionized while the composition includes an ionizing agent. Home use may be practiced, as embodiments include those in which the voltage or current of the power source cannot be adjusted by a user. Exemplary methods include the selection of a nail or diseased area to which treatment is desired and administering the kit as described.

Abstract: The invention is generally directed to a kit and patch for transdermal or intradermal delivery of at least one substance into the skin. The kit includes a dermal patch having an electrochemical cell with two electrodes and a retainer for retaining a conductive fluid which further includes an active substance. The conductive fluid can be deposited on at least one of the two electrodes. Alternatively, the conductive fluid can be applied topically to the skin.

Abstract: An adhesive bandage is provided. The adhesive bandage includes: (a) an absorbent pad having an absorbent surface; (b) an adhesive tape attached to the absorbent pad, the adhesive tape being configured for attaching to a skin region so as to position the absorbent surface against a portion of the skin region; (c) a display being positioned on an outer surface of the adhesive bandage the display being configured and positioned so as to be viewable by an individual when the adhesive tape is attached to the skin region; and (d) a power source attached to or integrated with the adhesive tape, the power source being for powering the display, the display being for increasing an acceptability of use of the adhesive bandage by the individual when powered. Furthermore, the present invention provides an adhesive bandage with a display, the display being for displaying a skin condition value and for increasing an acceptability of use of the adhesive bandage by the individual when powered.

Abstract: The invention is generally directed to a kit and patch for transdermal or intradermal delivery of at least one substance into the skin. The kit includes a dermal patch having an electrochemical cell with two electrodes and a retainer for retaining a conductive fluid which further includes an active substance. The conductive fluid can be deposited on at least one of the two electrodes. Alternatively, the conductive fluid can be applied topically to the skin.

Abstract: An RFID device including: electronic circuitry suitable for an RFID device comprising a radio frequency section; an antenna; a battery which provides the device with power; and at least one quarter wavelength transmission line coupled between the battery and one or both of the electronic circuitry and the antenna.

Abstract: The present invention provides a device for treatment of a nail condition comprising, at least one active electrode disposed on the nail, at least one counter electrode, at least one power source for providing power to the device, wherein the at least one power source is electrically coupled to the at least one active electrode and the at least one counter electrode; a controllable voltage converter coupled to the at least one power source; and a sensing means coupled to the nail and to the controllable voltage converter, wherein the sensing means is configured to facilitate adjustment of the output voltage of the power source according to the nail resistance to facilitate providing a constant current to the nail with high efficiency. The present invention is also directed to a method of providing a constant current to treat a nail condition.

Abstract: A method of forming an electrochemical cell is disclosed. The method comprises contacting a negative pole layer and a positive pole layer one with the other or with an optional layer interposed therebetween. The pole layers and the optional layer therebetween are selected so as to self-form an interfacial separator layer between the pole layers upon such contacting.

Abstract: The present invention is of an electrode comprising an electrode substrate base layer and a plurality of layers of insoluble pole electroactive substance disposed on the electrode substrate base layer, wherein each of the plurality of layers of insoluble pole electroactive substance is configured to facilitate a treatment of a condition. Further, the present invention is of use of the electrode in a currant generating treatment device.

Abstract: A radio frequency transponder includes at least one battery, which is coupled to provide electrical power for operating the transponder and at least one antenna, which is configured to receive and backscatter RF interrogation radiation from an interrogation device. An integrated circuit is arranged to store a code including information and, powered only with energy provided by the battery, to vary a radiation characteristic of the antenna responsively to the code so as to modulate the information onto the backscattered radiation.