Patents by Inventor Zymeworks Inc.

Zymeworks Inc. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable Heterodimeric Antibody Design with Mutations in the Fc Domain
    Publication number: 20130195849
    Abstract: The provided scaffolds have heavy chains that are asymmetric in the various domains (e.g. CH2 and CH3) to accomplish selectivity between the various Fc receptors involved in modulating effector function, beyond those achievable with a natural homodimeric (symmetric) Fc molecule, and increased stability and purity of the resulting variant Fc heterodimers. These novel molecules comprise complexes of heterogeneous components designed to alter the natural way antibodies behave and that find use in therapeutics.
    Type: Application
    Filed: November 2, 2012
    Publication date: August 1, 2013
    Applicant: Zymeworks Inc.
    Inventor: Zymeworks Inc.