Patents by Inventor ZymoGenetics, Inc.

ZymoGenetics, Inc. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130209470
    Abstract: The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17A and IL-17F. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. The present invention includes antibodies that bind both IL-17A and IL-17F, as well as methods of using the same in inflammation.
    Type: Application
    Filed: March 26, 2013
    Publication date: August 15, 2013
    Applicant: ZymoGenetics, Inc.
    Inventor: ZymoGenetics, Inc.
  • Publication number: 20130203070
    Abstract: The present invention relates to predicting therapeutic response of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cells in atopic dermatitis. The invention also includes methods of predicting a therapeutically responsive patient population.
    Type: Application
    Filed: March 13, 2013
    Publication date: August 8, 2013
    Applicant: ZymoGenetics, Inc.
    Inventor: ZymoGenetics, Inc.
  • Publication number: 20130142801
    Abstract: Antibodies that which specifically bind to mammalian cytokine-like polypeptide, called Zcyto10, are described. The antibodies include monoclonal antibodies and those that where the antibody is an antigen-binding fragment. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
    Type: Application
    Filed: January 18, 2013
    Publication date: June 6, 2013
    Applicant: ZYMOGENETICS, INC.
    Inventor: ZymoGenetics, Inc.
  • Publication number: 20130143265
    Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.
    Type: Application
    Filed: January 14, 2013
    Publication date: June 6, 2013
    Applicant: ZymoGenetics, Inc.
    Inventor: ZymoGenetics, Inc.
  • Publication number: 20130041143
    Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
    Type: Application
    Filed: October 11, 2012
    Publication date: February 14, 2013
    Applicant: ZymoGenetics, Inc.
    Inventor: ZymoGenetics, Inc.