Stent
A radially expandable stent comprising a plurality of spaced band-like elements and intersecting links is disclosed. The band-like elements have a generally serpentine configuration to provide continuous waves of generally sinusoidal character to each band-like element. The waves are characterized by a plurality of peaks and troughs taking a generally longitudinal direction along the cylinder such that the waves in the band-like elements open as the stent is expanded from a first diameter to a second diameter. The intersecting links are substantially U-shaped and terminate in first and second shanks. The first shank of a link emanates from a region between a peak and trough on a band-like element and the second shank of the link emanates from a region between a peak and trough on an adjacent band-like element.
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This invention relates to an endoprosthesis device for implantation within a body vessel, typically a blood vessel. More specifically, it relates to a tubular expandable stent of improved longitudinal flexibility.
BACKGROUND OF THE INVENTIONStents are placed or implanted within a blood vessel for treating stenoses, strictures or aneurysms therein. They are implanted to reinforce collapsing, partially occluded, weakened, or dilated sections of a blood vessel. They have also been implanted in the urinary tract and in bile ducts.
Typically, a stent will have an unexpanded (closed) diameter for placement and an expanded (opened) diameter after placement in the vessel or the duct. Some stents are self-expanding and some are expanded mechanically with radial outward force from within the stent, as by inflation of a balloon.
An example of the latter type is shown in U.S. Pat. No. 4,733,665 to Palmaz, which issued Mar. 29, 1988, and discloses a number of stent configurations for implantation with the aid of a catheter. The catheter includes an arrangement wherein a balloon inside the stent is inflated to expand the stent by plastically deforming it, after positioning it within a blood vessel.
A type of self-expanding stent is described in U.S. Pat. No. 4,503,569 to Dotter which issued Mar. 12, 1985, and discloses a shape memory stent which expands to an implanted configuration with a change in temperature. Other types of self-expanding stents not made of shape memory material are also known.
This invention is directed to stents of all these types when configured so as to be longitudinally flexible as described in detail hereinbelow. Flexibility is a desirable feature in a stent so as to conform to bends in a vessel. Such stents are known in the prior art. Examples are shown in U.S. Pat. No. 4,856,516 to Hillstead; U.S. Pat. No. 5,104,404 to Wolff; U.S. Pat. No. 4,994,071 to MacGregor; U.S. Pat. No. 5,102,417 to Palmaz; U.S. Pat. No. 5,195,984 to Schatz; U.S. Pat. No. 5,135,536 to Hillstead; U.S. Pat. 5,354,309 to Shepp-Pesch et al.; EPO Patent Application 0 540 290 A2 to Lau; EPO Patent Application No. 0 364 787 B1 to Schatz, and PCT Application WO 94/17754 (also identified as German Patent Application 43 03 181).
Generally speaking, these kinds of stents are articulated and are usually formed of a plurality of aligned, expandable, relatively inflexible, circular segments which are interconnected by flexible elements to form a generally tubular body which is capable of a degree of articulation or bending. Unfortunately, a problem with such stents is that binding, overlapping or interference can occur between adjacent segments on the inside of a bend due to the segments moving toward each other and into contact. Moreover, on the outside of a bend, the segments can move away from each other, leaving large gaps. This can lead to improper vessel support, vessel trauma, flow disturbance, kinking, balloon burst during expansion, and difficult recross for devices to be installed through already implanted devices and to unsupported regions of vessel.
A diamond configuration with diagonal connections between each and every diamond of each segment is also known but such closed configurations lack flexibility.
Such stents also suffer from the problem of shortening upon radial expansion. As the stent expands radially, it contracts lengthwise.
It is an object of this invention to provide a stent with a distributed structure which is longitudinally flexible that avoids these problems and exhibits improved flexibility in the stent body segments thereof rather than in flexible joints between the segments. It is a further object to provide stents that exhibit a desired lengthening or a desired shortening on radial expansion as well as stents which exhibit substantially no shortening or lengthening on radial expansion.
It is a further object of the present invention to provide a stent formed of a series of interconnected flexible cells.
It should be noted that for the purposes of this invention, the phrase generally sinusoidal is intended to include waves characterized by sine and cosine functions as well as waves which are not rigorously characterized by those functions, but nevertheless resemble such waves. In a more general way, such waves include those which are characterized as having one or more peaks and troughs. As an example, a wave whose peaks and troughs are U shaped or bulbous is intended to be included. Also intended to be included, without limiting the definition, are waves which are more triangular in shape such as a saw-tooth wave or waves whose peaks and troughs are rectangular.
SUMMARY OF THE INVENTIONThe present invention provides a radially expandable stent having first and second ends and a longitudinal axis. The stent comprises a plurality of spaced band-like elements forming a hollow cylinder. The band-like elements are arranged sequentially along the cylinder and each band-like element comprises one or more sub-elements having a generally serpentine configuration to provide continuous waves to each sub-element. The waves are characterized by a plurality of peaks and troughs taking a generally longitudinal direction along the cylinder such that the waves in the sub-elements open as the stent is expanded from a first diameter to a second diameter. Adjacent band-like elements in the stent are connected together by one or more links. Each link has at least one bend therein and terminates in first and second shanks. The first shank of each link emanates from a region of attachment between a peak and trough on a sub-element of a band-like element while the second shank of each link emanates from a region of attachment between a peak and trough on a sub-element of an adjacent band-like element. The first shanks attached to any given sub-element of a band-like element are spaced substantially one wavelength or more apart along the sub-element of a band-like element. Likewise, the second shanks attached to any given sub-element of a band-like element are spaced substantially one wavelength or more apart along the sub-element of the band-like element.
The present invention is also directed to a radially expandable stent comprising a plurality of spaced band-like elements forming a hollow cylinder. The band-like elements are arranged sequentially along the cylinder. Each band-like element has a generally serpentine configuration to provide continuous waves of generally sinusoidal character to each band-like element. The waves are characterized by a plurality of peaks and troughs taking a generally longitudinal direction along the cylinder, the peaks and troughs having a midpoint region midway between them, such that the waves in the band-like elements open as the stent is expanded from a first diameter to a second diameter. The stent further comprises one or more spaced generally longitudinal elements extending from the first end of the stent to the second end of the stent and having alternating peaks and troughs and longitudinal transition regions midway between adjacent peaks and troughs. Adjacent longitudinal elements are in phase with one another. Each generally longitudinal element intersects each band-like element in a region of intersection, which includes a region between a peak and a trough on a band-like element, and a transition region of a longitudinal element. Adjacent longitudinal elements intersect each band-like element at least one wavelength apart along the band-like element.
The present invention is further directed to an expandable stent which in expanded form comprises a plurality of flexible connected primary cells. Each primary cell comprises a first member having first and second ends extending in a direction generally perpendicular to the longitudinal axis of the stent and having a serpentine shape. The first members each have one peak and one trough, the peak and trough taking a generally longitudinal direction along the stent. Each primary cell further comprises a second member having first and second ends extending in a direction generally perpendicular to the longitudinal axis, and having a serpentine shape. The second members have one peak and one trough, the peak and trough taking a generally longitudinal direction along the stent. The second member is situated generally opposite the first member and is optionally out of phase with the first member. The primary cells also comprise a first link having a first end and a second end, and extending in a generally longitudinal direction. The first link has at least one bend therein and is disposed between the first end of the first member and the first end of the second member. The first end of the first link is attached to the first end of the first member and the second end of the first link is attached to the first end of the second member. Finally, each primary cell comprises a second link having a first end and a second end, extending in a generally longitudinal direction. The second link has at least one bend therein and is disposed between the second end of the first member and the second end of the second member. The first end of the second link is attached to second end of the first member and the second end of the second link is attached to the second end of the second member. The second link is in phase with the first link. The primary cells are arranged in one or more primary bands and adjacent primary bands are interconnected. Primary cells in adjacent bands may optionally be offset relative to one another along the bands.
Optionally, the stent may further comprise secondary bands comprised of secondary cells, the secondary bands alternating with the primary bands.
BRIEF DESCRIPTION OF THE FIGURES
While this invention may be embodied in many different forms, there are described in detail herein specific preferred embodiments of the invention. This description is an exemplification of the principles of the invention and is not intended to limit the invention to the particular embodiments illustrated.
For the sake of consistency, the terms ‘peak’ and ‘trough’ shall be defined with respect to the proximal and distal ends of the stent. As seen in the Figures, each of the stents has a proximal end designated by a numeral ending in 73 (e.g., 173) and a distal end designated by a numeral ending in 74 (e.g. 174). Peaks are concave relative to the proximal end of the stent and convex relative to the distal end of the stent. Troughs, on the other hand, are convex relative to the proximal end of the stent and concave relative to the distal end of the stent.
Moreover, for the sake of clarity, the terms ‘peak’ are ‘trough’ in reference to a band-like element or sub-element are intended to include not only the point(s) of maximum or minimum amplitude on a band-like element, but also a small region around the maximum or minimum. More precisely, in the case of peaks, the ‘small region’ around the maximum is intended to include any point along the band-like element which is distal of a line extending through the innermost part of the band-like element at the maximum amplitude and perpendicular to the longitudinal axis of the stent up to the peak itself. In the case of troughs, the ‘small region’ around the minimum is intended to include any point along the band-like element which is proximal of a line extending through the innermost part of the band-like element at the minimum amplitude and perpendicular to the longitudinal axis of the stent up to the trough itself. As seen in
Turning to the Figures,
The configuration can be seen in these Figures to be made up of a plurality of spaced band-like elements, generally indicated at 116, forming a hollow cylinder 120. Band-like elements 116 comprise one or more sub-elements. In the embodiment shown in
The inventive stents further comprise a plurality of links, each link having at least one bend therein. In the embodiment of
Although first shank 136 and second shank 140 are substantially perpendicular to the bands in the region of intersection between the shanks and the bands as depicted in
A minimum of one link 132 is required to connect adjacent band-like elements. Preferably, there will be a one-to-one correspondence between links and peaks (or troughs). Of course, any number of links intermediate between 1 and the number requisite for a one-to-one correspondence of peaks (troughs) and links may be used as well to join adjacent band-like elements.
For the sake of completeness, the stent of
The stent of
The stent, as seen in
Although first shank 136 and second shank 140 of links 132 are depicted in
In
In the embodiment shown in
In the embodiment shown in
In the embodiment shown in
Finally,
As in
The stent of
In another embodiment, as shown generally at 310a in
In another embodiment, as shown in
The stent of
In another embodiment, as shown in
For each first shank 436a attached to an intermediate band-like element 418a between a peak 424a and a trough 428a, there is a second shank 440a across the intermediate band-like element 418a and displaced from first shank 436a and located between the same peak and trough as is first shank 436a. First shanks 436a attached to any given band-like element 416a are spaced substantially one wavelength apart along the band-like element and similarly, second shanks 440a attached to any given band-like element 416a are spaced substantially one wavelength apart along the band-like element.
The stent of
In the expanded form, the stent can also clearly be seen to comprise a plurality of interconnected cells 480b, each cell having a first corner 481b, a second corner 482b, a third corner 483b and a fourth corner 484b. Links 432b forming the sides of cells 480b are seen to be substantially parallel to the longitudinal axis. As such, each cell is substantially aligned in the longitudinal direction. The third and fourth corners of primary cells and the first and second corners of abutting primary cells in adjacent bands are displaced only slightly relative to one or another so that as one traverses the stent from proximal end 473b to distal end 474b, the progression of cells from one end to the other end is slightly skewed relative to the longitudinal axis of the stent due to an artifact associated with the expansion of the balloon used to expand the stent.
In another embodiment shown in
The stent of
In yet another embodiment shown in
The stent of
While adjacent band-like elements are depicted in
Although
Further, while it is preferable for the band-like elements to be evenly spaced apart, it is not necessary. In the case where the bands are not evenly spaced, that is, different sets of adjacent bands are separated by different distances, the links may have differing wingspans (i.e. the distance from first shank to second shank). Moreover, even where the bands are evenly spaced apart, the links may have differing wingspans depending on where the shanks intersect the band-like elements.
It is understood that the present invention also contemplates substituting ‘U’ shaped links for zig-zag shaped links and vice versa as well as links with one or more bends therein. As such, the links shown in the various figures are all interchangeable, allowing for minor modifications to allow for the requisite orientation of the shanks. Preferably, the links will exhibit a degree of flexibility, thereby contributing to the overall flexibility of the cells.
Although most of the figures show the inventive stents in the flat for clarity, it is understood that the stents may be formed into as tubular shape by rolling the flat patterns shown about the longitudinal axis so as to bring the edges and together, as shown in
The invention further contemplates a radially expandable stent having first and second ends and comprising a plurality of spaced band-like elements forming a hollow cylinder, and a plurality of spaced generally longitudinal elements intersecting the bands and extending from one end of the stent to the other. The band-like elements are arranged sequentially along the cylinder. Each band-like element has a generally serpentine configuration to provide continuous waves of generally sinusoidal character to each band-like element. The waves are characterized by a plurality of peaks and troughs taking a generally longitudinal direction along the cylinder. Midway between the peaks and troughs is a midpoint region. Preferably, adjacent bands will be out of phase with each other by 180°.
The plurality of spaced generally longitudinal elements have alternating peaks and troughs and longitudinal transition regions midway between adjacent peaks and troughs. Each generally longitudinal element intersects each band like element in a region of intersection which includes a transition region of a longitudinal element and a midpoint region of a band. Each generally longitudinal element may, but need not be substantially perpendicular to each band like element in each region of intersection in the unexpanded stent. The longitudinal transition region of the longitudinal elements may be zig-zag shaped or substantially ‘S’ shaped.
The inventive stents are also designed so as to have desired shortening or lengthening characteristics upon radial expansion. The exact shortening or lengthening characteristics will depend on the placement of the shanks relative to the midpoint positions on the band-like elements between adjacent peaks and troughs. The midpoint position is defined to be the position midway between an adjacent peak and trough on a band-like element. One such midpoint is designated by numeral 126 in
Although all of the stents, with the exception of that shown in
As already indicated, this invention is applicable to self-expanding configurations, mechanically expandable configurations and to stents made of a wide variety of materials, including metal, plastic and any other material capable of functioning as an expandable stent. For example, the stent may be of metal wire or ribbon such as tantalum, stainless steel or the like or of metal sheeting or metal tubing. It may be thin-walled. It may be of shape memory alloy such as Nitinol or the like.
The figures disclosed herein are not intended to be limited to the stents shown but are further intended to convey equivalent structures such as stents which are the mirror images of an embodiment, and stents whose patterns may derived from the patterns shown here via a variety of symmetry operations such as reflections, rotations and inversions and combinations thereof about a given point, line or plane, as well as other equivalent structures.
The above Examples and disclosure are intended to be illustrative and not exhaustive. These examples and description will suggest many variations and alternatives to one of ordinary skill in this art. All these alternatives and variations are intended to be included within the scope of the attached claims. Those familiar with the art may recognize other equivalents to the specific embodiments described herein which equivalents are also intended to be encompassed by the claims attached hereto.
Claims
1-61. (Cancelled)
62. A medical device comprising:
- a stent, the stent comprising a hollow, cylindrical body comprised of a first ring and a second ring, the first and the second rings each extending circumferentially around the cylindrical body, the first and second rings each including an undulating series of peaks and valleys;
- a first inflection point on the first ring, the first inflection point disposed on an intermediate portion of the first ring substantially centered between an adjacent peak and valley, the first inflection point including a portion extending generally circumferentially;
- a second inflection point on the second ring, the second inflection point disposed on an intermediate portion of the second ring substantially centered between an adjacent peak and valley, the second inflection point including a portion extending generally circumferentially;
- a link joined at a first end at the first inflection point on the first ring and at a second end at the second inflection point whereby the first and second rings are joined together.
63. A medical device as in claim 1 wherein the link includes at least two curved segments.
64. A medical device as in claim 1 wherein the portion of the inflection point extending generally circumferentially has a length measured circumferentially which is substantially equal to a width of the link to which it is attached.
65. A medical device as in claim 1 wherein a portion of the link near its first end nests within the undulating series of peak and valleys of the first ring of the stent.
66. A medical device as in claim 1 wherein the undulating peaks and valleys of each of the first and second rings are formed by opposing curved segments joined to each other by straight segments.
67. A medical device as in claim 66 wherein at least one of the straight segments is interrupted by an inflection point which produces a generally circumferentially offset portion in the straight segment.
68. A medical device as in claim 1 wherein no more than one link is connected to either of the first and second inflection points.
69. A medical device as in claim 1 wherein the undulating peaks and valleys of the first ring are arranged with the undulating peaks and valleys of the second ring such that the first and second rings appear as mirror images of each other.
70. A medical device as in claim 1 wherein the undulating peaks and valleys the first ring are arranged with the undulating peaks and valleys of the second ring such that the first and second rings have peaks and valleys which are paired with each other in an in-phase relationship.
71. A medical device as in claim 1 wherein the first and second rings each include the same number of inflection points.
72. A medical device as in claim 1 wherein the first and second rings are joined by a plurality of links.
73. A medical device as in claim 13 wherein the plurality of links have complimentary shapes such that they will nest.
74. A medical device comprising:
- a stent, the stent comprising a hollow, cylindrical body comprised of at least one ring, the ring extending circumferentially around the cylindrical body, the ring including an undulating series of peaks and valleys;
- an inflection point on the ring, the inflection point disposed on an intermediate portion of the ring substantially centered between an adjacent peak and valley;
- a first link joined at an end at the inflection point.
75. A medical device as in claim 74 wherein the inflection point includes a short portion extending generally circumferentially.
76. A medical device as in claim 75 wherein the short portion of the inflection point extending generally circumferentially has a length measured circumferentially which is substantially equal to a width of the link.
77. A medical device as in claim 74 wherein the link extends substantially parallel to a portion of the ring.
78. A medical device as in claim 74 wherein the link extends beyond a peak or valley of the ring.
79. A medical device as in claim 74 also comprising a second link joined at an end at the inflection point and extending from the inflection point in a direction substantially opposite to the first link.
80. A medical device as in claim 79 wherein the first link is joined at an upper portion of the inflection point and the second link is joined at a lower portion of the inflection point.
81. A medical device as in claim 79 wherein the first link is joined to the ring above the ring and the second link is joined to the ring below the ring.
82. A medical device as in claim 74 wherein a portion of the link nests within the undulating series of peaks and valleys of the ring.
83. A medical device as in claim 74 wherein the undulating peaks and valleys of the ring are formed by opposing curved segments joined to each other by straight segments.
84. A medical device as in claim 83 wherein the inflection point forms an offset at at least one of the straight segments to produce a generally circumferentially offset portion in the straight segment.
85. A medical device as in claim 74 wherein the ring includes a plurality of inflection points and a plurality of links joined to the inflection points.
86. A medical device as in claim 85 wherein each peak and valley has an inflection point therebetween and a first link joined at each inflection point.
87. A medical device as in claim 86 wherein each inflection point has a second link joined at each inflection point and extending longitudinally opposite the first link.
88. A medical device as in claim 86 wherein the plurality of links have complimentary shapes such that they will nest.
Type: Application
Filed: Aug 17, 2004
Publication Date: Jan 27, 2005
Applicant: SCIMED LIFE SYSTEMS, INC. (Maple Grove, MN)
Inventors: Graig Kveen (Maple Grove, MN), Timothy Ehr (Elk River, MN), Brian Brown (Hanover, MN)
Application Number: 10/920,076