Streptococcus pneumoniae proteins and nucleic acid molecules

Abstract

Novel protein antigens from Streptococcus pneumoniae are disclosed, together with nucleic acid sequences encoding them. Their use in vaccines and in screening methods is also described.

Description

The present invention relates to proteins derived from Streptococcus pneumoniae, nucleic acid molecules encoding such proteins, the use of the nucleic acid and/or proteins as antigens/immunogens and in detection/diagnosis, as well as, methods for screening the proteins/nucleic acid sequences as potential anti-microbial targets.

Streptococcus pneumoniae, commonly referred to as the pneumococcus, is an important pathogenic organism. The continuing significance of Streptoccocus pneumoniae infections in relation to human disease in developing and developed countries has been authoritatively reviewed (Fiber, G. R., Science, 265: 1385-1387 (1994)). That indicates that on a global scale this organism is believed to be the most common bacterial cause of acute respiratory infections, and is estimated to result in 1 million childhood deaths each year, mostly in developing countries (Stansfield, S. K., Pediatr. Infect. Dis., 6: 622 (1987)). In the USA it has been suggested (Breiman et al., Arch. Intern. Med., 150: 1401 (1990)) that the pneumococcus is still the most common cause of bacterial pneumonia, and that disease rates are particularly high in young children, in the elderly, and in patients with predisposing conditions such as asplenia, heart, lung and kidney disease, diabetes, alcoholism, or with immunosupressive disorders, especially AIDS. These groups are at higher risk of pneumococcal septicaemia and hence meningitis and therefore have a greater risk of dying from pneumococcal infection. The pneumococcus is also the leading cause of otitis media and sinusitis, which remain prevalent infections in children in developed countries, and which incur substantial costs.

The need for effective preventative strategies against pneumococcal infection is highlighted by the recent emergence of penicillin-resistant pneumococci. It has been reported that 6.6% of pneumoccal isolates in 13 US hospitals in 12 states were found to be resistant to penicillin and some isolates were also resistant to other antibiotics including third generation cyclosporins (Schappert, S. M., Vital and Health Statistics of the Centres for Disease Control/National Centre for Health Statistics, 214:1 (1992)). The rates of penicillin resistance can be higher (up to 20%) in some hospitals (Breiman et al, J. Am. Med. Assoc., 271: 1831 (1994)). Since the development of penicillin resistance among pneumococci is both recent and sudden, coming after decades during which penicillin remained an effective treatment, these findings are regarded as alarming.

For the reasons given above, there are therefore compelling grounds for considering improvements in the means of preventing, controlling, diagnosing or treating pneumococcal diseases.

Various approaches have been taken in order to provide vaccines for the prevention of pneumococcal infections. Difficulties arise for instance in view of the variety of serotypes (at least 90) based on the structure of the polysaccharide capsule surrounding the organism. Vaccines against individual serotypes are not effective against other serotypes and this means that vaccines must include polysaccharide antigens from a whole range of serotypes in order to be effective in a majority of cases. An additional problem arises because it ahs been found that the capsular polysaccharides (each of which determines the serotype and is the major protective antigen) when purified and used as a vaccine do not reliably induce protective antibody responses in children under two years of age, the age group which suffers the highest incidence of invasive pneumococcal infection and meningitis.

A modification of the approach using capsule antigens relies on conjugating the polysaccharide to a protein in order to derive an enhanced immune response, particularly by giving the response T-cell dependent character. This approach has been used in the development of a vaccine against Haemophilus influenzae. There are issues of cost concerning both the multi-polysaccharide vaccines and those based on conjugates.

A third approach is to look for other antigenic components which offer the potential to be vaccine candidates. In the present application we provide a group of proteins antigens which are secreted/exported proteins.

Thus, in a first aspect the present invention provides a Streptococcus pneumoniae protein or polypeptide having a sequence selected from those shown in table 2 herein.

A protein or polypeptide of the present invention may be provided in substantially pure form. For example, it may be provided in a form which is substantially free of other proteins.

In a preferred embodiment, a protein or polypeptide having an amino acid sequence as shown in Table 3 is provided.

The invention encompasses any protein coded for by a nucleic acid sequence as shown in Table 1 herein.

As discussed herein, the proteins and polypeptides of the invention are useful as antigenic material. Such material can be “antigenic” and/or “immunogenic”. Generally, “antigenic” is taken to mean that the protein or polypeptide is capable of being used to raise antibodies or indeed is capable of inducing an antibody response in a subject. “Immunogenic” is taken to mean that the protein or polypeptide is capable of eliciting a protective immune response in a subject. Thus, in the latter case, the protein or polypeptide may be capable of not only generating an antibody response and in addition non-antibody based immune responses.

The skilled person will appreciate that homologues or derivatives of the proteins or polypeptides of the invention will also find use in the context of the present invention, ie as antigenic/immunogenic material. Thus, for instance proteins or polypeptides which include one or more additions, deletions, substitutions or the like are encompassed by the present invention. In addition, it may be possible to replace one amino acid with another of similar “type”. For instance replacing one hydrophobic amino acid with another. One can use a program such as the CLUSTAL program to compare amino acid sequences. This program compares amino acid sequences and finds the optimal alignment by inserting spaces in either sequence as appropriate. It is possible to calculate amino acid identity or similarity (identity plus conservation of amino acid type) for an optimal alignment. A program like BLASTx will align the longest stretch of similar sequences and assign a value to the fit. It is thus possible to obtain a comparison where several regions of similarity are found, each having a different score. Both types of analysis are contemplated in the present invention.

In the case of homologues and derivatives, the degree of identity with a protein or polypeptide as described herein is less important than that the homologue or derivative should retain its antigenicity or immunogenicity to streptoccocus pneumoniae. However, suitably, homologues or derivatives having at least 60% similarity (as discussed above) with the proteins or polypeptides described herein are provided.

Preferably, homologues or derivatives having at least 70% similarity, more preferably at least 80% similarity are provided. Most preferably, homologues or derivatives having at least 90% or even 95% similarity are provided.

In an alternative approach, the homologues or derivatives could be fusion proteins, incorporating moieties which render purification easier, for example by effectively tagging the desired protein or polypeptide. It may be necessary to remove the “tag” or it may be the case that the fusion protein itself retains sufficient antigenicity to be useful.

In an additional aspect of the invention there are provided antigenic fragments of the proteins or polypeptides of the invention, or of homologues or derivatives thereof.

For fragments of the proteins or polypeptides described herein, or of homologues or derivatives thereof, the situation is slightly different. It is well known that is possible to screen an antigenic protein or polypeptide to identify epitopic regions, ie those regions which are responsible for the protein or polypeptide's antigenicity or immunogenicity. Methods for carrying out such screening are well known in the art. Thus, the fragments of the present invention should include one or more such epitopic regions or be sufficiently similar to such regions to retain their antigenic/immunogenic properties. Thus, for fragments according to the present invention the degree of identity is perhaps irrelevant, since they may be 100% identical to a particular part of a protein or polypeptide, homologue or derivative as described herein. The key issue, once again, is that the fragment retains the antigenic/immunogenic properties.

Thus, what is important for homologues, derivatives and fragments is that they possess at least a degree of the antigenicity/immunogenicity of the protein or polypeptide from which they are derived.

Gene cloning techniques may be used to provide a protein of the invention in substantially pure form. These techniques are disclosed, for example, in J. Sambrook et al Molecular Cloning 2nd Edition, Cold Spring Harbor Laboratory Press (1989). Thus, in a fourth aspect, the present invention provides a nucleic acid molecule comprising or consisting of a sequence which is:

• • (i) any of the DNA sequences set out in Table 1 or their RNA equivalents;
  • (ii) a sequence which is complementary to any of the sequences of (i);
  • (iii) a sequence which codes for the same protein or polypeptide, as those sequences of (i) or (ii);
  • (iv) a sequence which is has substantial identity with any of those of (i), (ii) and (iii);
  • (v) a sequence which codes for a homologue, derivative or fragment of a protein as defined in Table 1.

In a fifth aspect the present invention provides a nucleic acid molecule comprising or consisting of a sequence which is:

• • (i) any of the DNA sequences set out in Table 4 or their RNA equivalents;
  • (ii) a sequence which is complementary to any of the sequences of (i);
  • (iii) a sequence which codes for the same protein or polypeptide, as those sequences of (i) or (ii);
  • (iv) a sequence which is has substantial identity with any of those of (i), (ii) and (iii);
  • (v) a sequence which codes for a homologue, derivative or fragment of a protein as defined in Table 4.

The nucleic acid molecules of the invention may include a plurality of such sequences, and/or fragments. The skilled person will appreciate that the present invention can include, novel variants of those particular novel nucleic acid molecules which are exemplified herein. Such variants are encompassed by the present invention. These may occur in nature, for example because of strain variation. For example, additions, substitutions and/or deletions are included. In addition, and particularly when utilising microbial expression systems, one may wish to engineer the nucleic acid sequence by making use of known preferred codon usage in the particular organism being used for expression. Thus, synthetic or non-naturally occurring variants are also included within the scope of the invention.

The term “RNA equivalent” when used above indicates that a given RNA molecule has a sequence which is complementary to that of a given DNA molecule (allowing for the fact that in RNA “U” replaces “T” in the genetic code).

When comparing nucleic acid sequences for the purposes of determining the degree of homology or identity one can use programs such as BESTFIT and GAP (both from the Wisconsin Genetics Computer Group (GCG) software package) BESTFIT, for example, compares two sequences and produces an optimal alignment of the most similar segments. GAP enables sequences to be aligned along their whole length and finds the optimal alignment by inserting spaces in either sequence as appropriate. Suitably, in the context of the present invention compare when discussing identity of nucleic acid sequences, the comparison is made by alignment of the sequences along their whole length.

Preferably, sequences which have substantial identity have at least 50% sequence identity, desirably at least 75% sequence identity and more desirably at least 90 or at least 95% sequence identity with said sequences. In some cases the sequence identity may be 99% or above.

Desirably, the term “substantial identity” indicates that said sequence has a greater degree of identity with any of the sequences described herein than with prior art nucleic acid sequences.

It should however be noted that where a nucleic acid sequence of the present invention codes for at least part of a novel gene product the present invention includes within its scope all possible sequence coding for the gene product or for a novel part thereof.

The nucleic acid molecule may be in isolated or recombinant form. It may be incorporated into a vector and the vector may be incorporated into a host. Such vectors and suitable hosts form yet further aspects of the present invention.

Therefore, for example, by using probes based upon the nucleic acid sequences provided herein, genes in Streptococcus pneumoniae can be identified. They can then be excised using restriction enzymes and cloned into a vector. The vector can be introduced into a suitable host for expression.

Nucleic acid molecules of the present invention may be obtained from S. pneumoniae by the use of appropriate probes complementary to part of the sequences of the nucleic acid molecules. Restriction enzymes or sonication techniques can be used to obtain appropriately sized fragments for probing.

Alternatively PCR techniques may be used to amplify a desired nucleic acid sequence. Thus the sequence data provided herein can be used to design two primers for use in PCR so that a desired sequence, including whole genes or fragments thereof, can be targeted and then amplified to a high degree. One primer will normally show a high degree of specificity for a first sequence located on one strand of a DNA molecule, and the other primer will normally show a high degree of specificity for a second sequence located on the complementary strand of the DNA sequence and being spaced from the complementary sequence to the first sequence.

Typically primers will be at least 15-25 nucleotides long.

As a further alternative chemical synthesis may be used. This may be automated. Relatively short sequences may be chemically synthesised and ligated together to provide a longer sequence.

In yet a further aspect the present invention provides an immunogenic/antigenic composition comprising one or more proteins or polypeptides selected from those whose sequences are shown in Tables 2-4, or homologues or derivatives thereof, and/or fragments of any of these. In preferred embodiments, the immunogenic/antigenic composition is a vaccine or is for use in a diagnostic assay.

In the case of vaccines suitable additional excipients, diluents, adjuvants or the like may be included. Numerous examples of these are well known in the art.

It is also possible to utilise the nucleic acid sequences shown in Table 1 in the preparation of so-called DNA vaccines. Thus, the invention also provides a vaccine composition comprising one or more nucleic acid sequences as defined herein. The use of such DNA vaccines is described in the art. See for instance, Donnelly et al, Ann. Rev. Immunol., 15:617-648 (1997).

As already discussed herein the proteins or polypeptides described herein, their homologues or derivatives, and/or fragments of any of these, can be used in methods of detecting/diagnosing S. pneumoniae. Such methods can be based on the detection of antibodies against such proteins which may be present in a subject. Therefore the present invention provides a method for the detection/diagnosis of S. pneumoniae which comprises the step of bringing into contact a sample to be tested with at least one protein, or homologue, derivative or fragment thereof, as described herein. Suitably, the sample is a biological sample, such as a tissue sample or a sample of blood or saliva obtained from a subject to be tested.

In an alternative approach, the proteins described herein, or homologues, derivatives and/or fragments thereof, can be used to raise antibodies, which in turn can be used to detect the antigens, and hence S. pneumoniae. Such antibodies form another aspect of the invention. Antibodies within the scope of the present invention may be monoclonal or polyclonal.

Polyclonal antibodies can be raised by stimulating their production in a suitable animal host (e.g. a mouse, rat, guinea pig, rabbit, sheep, goat or monkey) when a protein as described herein, or a homologue, derivative or fragment thereof, is injected into the animal. If desired, an adjuvant may be administered together with the protein. Well-known adjuvants include Freund's adjuvant (complete and incomplete) and aluminium hydroxide. The antibodies can then be purified by virtue of their binding to a protein as described herein.

Monoclonal antibodies can be produced from hybridomas. These can be formed by fusing myeloma cells and spleen cells which produce the desired antibody in order to form an immortal cell line. Thus the well-known Kohler & Milstein technique (Nature 256 (1975)) or subsequent variations upon this technique can be used.

Techniques for producing monoclonal and polyclonal antibodies that bind to a particular polypeptide/protein are now well developed in the art. They are discussed in standard immunology textbooks, for example in Roitt et al, Immunology second edition (1989), Churchill Livingstone, London.

In addition to whole antibodies, the present invention includes derivatives thereof which are capable of binding to proteins etc as described herein. Thus the present invention includes antibody fragments and synthetic constructs. Examples of antibody fragments and synthetic constructs are given by Dougall et al in Tibtech 12 372-379 (September 1994).

Antibody fragments include, for example, Fab, F(ab′)₂ and Fv fragments. Fab fragments (These are discussed in Roitt et al [supra]) Fv fragments can be modified to produce a synthetic construct known as a single chain Fv (scFv) molecule. This includes a peptide linker covalently joining V_h and V_l regions, which contributes to the stability of the molecule. Other synthetic constructs that can be used include CDR peptides. These are synthetic peptides comprising antigen-binding determinants. Peptide mimetics may also be used. These molecules are usually conformationally restricted organic rings that mimic the structure of a CDR loop and that include antigen-interactive side chains.

Synthetic constructs include chimaeric molecules. Thus, for example, humanised (or primatised) antibodies or derivatives thereof are within the scope of the present invention. An example of a humanised antibody is an antibody having human framework regions, but rodent hypervariable regions. Ways of producing chimaeric antibodies are discussed for example by Morrison et al in PNAS, 81, 6851-6855 (1984) and by Takeda et al in Nature. 314, 452-454 (1985).

Synthetic constructs also include molecules comprising an additional moiety that provides the molecule with some desirable property in addition to antigen binding. For example the moiety may be a label (e.g. a fluorescent or radioactive label). Alternatively, it may be a pharmaceutically active agent.

Antibodies, or derivatives thereof, find use in detection/diagnosis of S. pneumoniae. Thus, in another aspect the present invention provides a method for the detection/diagnosis of S. pneumoniae which comprises the step of bringing into contact a sample to be tested and antibodies capable of binding to one or more proteins described herein, or to homologues, derivatives and/or fragments thereof.

In addition, so-called “Affibodies” may be utilised. These are binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain (Nord et al,) Thus, Small protein domains, capable of specific binding to different target proteins can be selected using combinatorial approaches.

It will also be clear that the nucleic acid sequences described herein may be used to detect/diagnose S. pneumoniae. Thus, in yet a further aspect, the present invention provides a method for the detection/diagnosis of S. pneumoniae which comprises the step of bringing into contact a sample to be tested with at least one nucleic acid sequence as described herein. Suitably, the sample is a biological sample, such as a tissue sample or a sample of blood or saliva obtained from a subject to be tested. Such samples may be pre-treated before being used in the methods of the invention. Trhus, for example, a sample may be treated to extract DNA. Then, DNA probes based on the nucleic acid sequences described herein (ie usually fragments of such sequences) may be used to detect nucleic acid from S. pneumoniae.

In additional aspects, the present invention provides:

• (a) a method of vaccinating a subject against S. pneumoniae which comprises the step of administering to a subject a protein or polypeptide of the invention, or a derivative, homologue or fragment thereof, or an immunogenic composition of the invention;
• (b) a method of vaccinating a subject against S. pneumoniae which comprises the step of administering to a subject a nucleic acid molecule as defined herein;
• (c) a method for the prophylaxis or treatment of S. pneumoniae infection which comprises the step of administering to a subject a protein or polypeptide of the invention, or a derivative, homologue or fragment thereof, or an immunogenic composition of the invention;
• (d) a method for the prophylaxis or treatment of S. pneumoniae infection which comprises the step of administering to a subject a nucleic acid molecule as defined herein;
• (e) a kit for use in detecting/diagnosing S. pneumoniae infection comprising one or more proteins or polypeptides of the invention, or homologues, derivatives or fragments thereof, or an antigenic composition of the invention; and
• (f) a kit for use in detecting/diagnosing S. pneumoniae infection comprising one or more nucleic acid molecules as defined herein.

Given that we have identified a group of important proteins, such proteins are potential targets for anti-microbial therapy. It is necessary, however, to determine whether each individual protein is essential for the organism's viability. Thus, the present invention also provides a method of determining whether a protein or polypeptide as described herein represents a potential anti-microbial target which comprises inactivating said protein and determining whether S. pneumoniae is still viable, in vitro or in vivo.

A suitable method for inactivating the protein is to effect selected gene knockouts, ie prevent expression of the protein and determine whether this results in a lethal change. Suitable methods for carrying out such gene knockouts are described in Li et al, P.N.A.S., 94:13251-13256 (1997).

In a final aspect the present invention provides the use of an agent capable of antagonising, inhibiting or otherwise interfering with the function or expression of a protein or polypeptide of the invention in the manufacture of a medicament for use in the treatment or prophylaxis of S. pneumoniae infection.

The invention will now be described with reference to the following examples, which should not be construed as in any way limiting the invention. The examples refer to the figures in which:

FIG. 1: shows the results of various DNA vaccine trials; and

FIG. 2: shows the results of further DNA vaccine trials.

EXAMPLE 1

The Genome sequencing of Streptococcus pneumoniae type 4 is in progress at the Institute for Genomic Research (TIGR, Rockville, Md., USA). Up to now, the whole sequence has not been completed or published. On 21 Nov. 1997, the TIGR centre released some DNA sequences as contigs which are not accurate reflections of the finished sequence. These contigs can be downloaded from their Webster (www@tigr.org). We downloaded these contigs and created a local database using the application GCGToBLAST (Wisconsin Package Version 9.1, Genetics Computer Group (GCG), Madison, USA). This database can be searched with the FastA and TfastA procedures (using the method of Pearson and Lipman (PNAS USA, 85:2444-2448 (1988)).

Using FastA and TfastA procedures, the local pneumococcus database was searched for putative leader sequence or anchor sequence features. Relevant sequences were used to interrogate for comparative novel sequences. These were:

• • (i) already described leader sequences of Streptococcus pneumoniae (from proteins NanA, NanB, LytA, PapA, pcpA, PsaA and PspA);
  • (ii) the leader sequence of Usp45, a secreted protein from Lactococcus lactis;
  • (iii) new hypothetical leader sequences derived from the searches in (i) and (ii);
  • (iv) the anchor motif LPxTG, a feature common to many Gram-positive bacteria surface proteins which are anchored by a mechanism involving the Sortase complex proteins.

Provided below is an example of this approach, with reference to the sequences derived from the database (see table 1).

The protein leader sequences of different known exported proteins were used as a starting point for a search of the local pneumococcus database described above. The hypothetical proteins found with this search were then submitted to a Blast search in general databases such as EMBL, Swissprot etc. Proteins remaining unknown in the pneumococcus are kept and annotated. Then the search is performed again using the new potential protein leader sequence as a probe, using the TfastA procedure.

EXAMPLE 2

DNA Vaccine Trials

pcDNA3.1+ as a DNA Vaccine Vector

pcDNA3.1+

The vector chosen for use as a DNA vaccine vector was pcDNA3.1 (Invitrogen) (actually pcDNA3.1+, the forward orientation was used in all cases but may be referred to as pcDNA3.1 here on). This vector has been widely and successfully employed as a host vector to test vaccine candidate genes to give protection against pathogens in the literature (Zhang, et al., Kurar and Splitter, Anderson et al.). The vector was designed for high-level stable and non-replicative transient expression in mammalian cells. pcDNA3.1 contains the ColE1 origin of replication which allows convenient high-copy number replication and growth in E. coli. This in turn allows rapid and efficient cloning and testing of many genes. The pcDNA3.1 vector has a large number of cloning sites and also contains the gene encoding ampicillin resistance to aid in cloning selection and the human cytomegalovirus (CMV) immediate-early promoter/enhancer which permits efficient, high-level expression of the recombinant protein. The CMV promoter is a strong viral promoter in a wide range of cell types including both muscle and immune (antigen presenting) cells. This is important for optimal immune response as it remains unknown as to which cells types are most important in generating a protective response in vivo. A T7 promoter upstream of the multiple cloning site affords efficient expression of the modified insert of interest and which allows in vitro transcription of a cloned gene in the sense orientation.

• Zhang, D., Yang, X., Berry, J. Shen, C., McClarty, G. and Brunham, R. C. (1997) “DNA vaccination with the major outer-membrane protein genes induces acquired immunity to Chlamydia trachomatis (mouse pneumonitis) infection”. Infection and Immunity, 176, 1035-40.
• Kurar, E. and Splitter, G. A. (1997) “Nucleic acid vaccination of Brucella abortus ribosomal L7/L12 gene elicits immune response”. Vaccine, 15, 1851-57.
• Anderson, R., Gao, X.-M., Papakonstantinopoulou, A., Roberts, M. and Dougan, G. (1996) “Immune response in mice following immunisation with DNA encoding fragment C of tetanus toxin”. Infection and Immunity, 64, 3168-3173.
  Preparation of DNA Vaccines

Oligonucleotide primers were designed for each individual gene of interest derived using the LEEP system. Each gene was examined thoroughly, and where possible, primers were designed such that they targeted that portion of the gene thought to encode only the mature portion of the gene protein. It was hoped that expressing those sequences that encode only the mature portion of a target gene protein, would facilitate its correct folding when expressed in mammalian cells. For example, in the majority of cases primers were designed such that putative N-terminal signal peptide sequences would not be included in the final amplification product to be cloned into the pcDNA3.1 expression vector. The signal peptide directs the polypeptide precursor to the cell membrane via the protein export pathway where it is normally cleaved off by signal peptidase I (or signal peptidase II if a lipoprotein). Hence the signal peptide does not make up any part of the mature protein whether it be displayed on the surface of the bacteria surface or secreted. Where a N-terminal leader peptide sequence was not immediately obvious, primers were designed to target the whole of the gene sequence for cloning and ultimately, expression in pcDNA3.1.

Having said that, however, other additional features of proteins may also affect the expression and presentation of a soluble protein. DNA sequences encoding such features in the genes encoding the proteins of interest were excluded during the design of oligonucleotides. These features included:

• 1. LPXTG cell wall anchoring motifs.
• 2. LXXC ipoprotein attachment sites.
• 3. Hydrophobic C-terminal domain.
• 4. Where no N-terminal signal peptide or LXXC was present the start codon was excluded.
• 5. Where no hydrophobic C-terminal domain or LPXTG motif was present the stop codon was removed.

Appropriate PCR primers were designed for each gene of interest and any and all of the regions encoding the above features was removed from the gene when designing these primers. The primers were designed with the appropriate enzyme restriction site followed by a conserved Kozak nucleotide sequence (in all cases) GCCACC was used. The Kozak sequence facilitates the recognition of initiator sequences by eukaryotic ribosomes) and an ATG start codon upstream of the insert of the gene of interest. For example the forward primer using a BamH1 site the primer would begin GCGGGATCCGCCACCATG followed by a small section of the 5′ end of the gene of interest. The reverse primer was designed to be compatible with the forward primer and with a Not1 restriction site at the 5′ end in all cases (this site is TTGCGGCCGC).

PCR Primers

The following PCR primers were designed and used to amplify the truncated genes of interest.

ID210
Forward Primer 5′ CGGATCCGCCACCATGTCTTCTAATGAATCTGCCGATG 3′
Reverse Primer 5′ TTGCGGCCGCCTGTTTAGATTGGATATCTGTAAAGACTT 3′
4172.5
Forward Primer 5′ CGCGGATCCGCCACCATGGATTTTCCTTCAAATTTGGAGG 3′
Reverse Primer 5′ TTGCGGCCGCACCGTACTGGCTGCTGACT 3′
ID211
Forward Primer 5′ CGGATCCGCCACCATGAGTGAGATCAAAATTATTAACGC 3′
Reverse Primer 5′ TTGCGGCCGCCGTTCCATGGTTGACTCCT 3′
4197.4
Forward Primer 5′ CGCGGATCCGCCACCATGTGGGACATATTGGTGGAAAC 3′
Reverse Primer 5′ TTGCGGCCGCTTCACTTGAGCAAACTGAATCC 3′
4122.1
Forward Primer 5′ CGCGGATCCGCCACCATGTCACAAGAAAAAACAAAAAATGAA 3′
Reverse Primer 5′ TTGCGGCCGCATCGACGTAGTCTCGGCC 3′
4126.7
Forward Primer 5′ CGCGGATCCGCCACCATGCTGGTTGGAACTTTCTACTATCAAT 3′
Reverse Primer 5′ TTGCGGCCGCAACTTTCGTCCCTTTTTGG 3′
4188.11
Forward Primer 5′ CGCGGATCCGCCACCATGGGCAATTCTGGCGGAA 3′
Reverse Primer 5′ TTGCGGCCGCTTGTTTCATAGCTTTTTTGATTGTT 3′
ID209
Forward Primer 5′ GGCGGATCCGCCACCATGCTATTGATACGAAATGCAGGG 3′
Reverse Primer 5′ TTGCGGCCGCAACATAATCTAGTAAATAAGCGTAGCC 3′
ID215
Forward Primer 5′ CGCGGATCCGCCACCATGACGGCGACGAATTTTC 3′
Reverse Primer 5′ TTGCGGCCGCTTAATTCGTTTTTGAACTAGTTGCT 3′
4170.4
Forward Primer 5′ CGCGGATCCGGCACCATGGCTGTTTTTCTTCGCTATCATG 3′
Reverse Primer 5′ TTGCGGCCGCTTTCTTCAACAAACCTTGTTCTTG 3′
4193.1
Forward Primer 5′ CGCGGATCCGCCACCATGGGTAACCGCTCTTCTCGTAAC 3′
Reverse Primer 5′ TTGCGGCCGCGCTTCCATCAAGGATTTTAGC 3′

Cloning

The insert along with the flanking features described above was amplified using PCR against a template of genomic DNA isolated from type 4 S. pneumoniae strain 11886 obtained from the National Collection of Type Cultures. The PCR product was cut with the appropriate restriction enzymes and cloned in to the multiple cloning site of pcDNA3.1 using conventional molecular biological techniques. Suitably mapped clones of the genes of interested were cultured and the plasmids isolated on a large scale (>1.5 mg) using Plasmid Mega Kits (Qiagen). Successful cloning and maintenance of genes was confirmed by restriction mapping and sequencing ˜700 base pairs through the 5′ cloning junction of each large scale preparation of each construct.

Strain Validation

A strain of type 4 was used in cloning and challenge methods which is the strain from which the S. pneumoniae genome was sequenced. A freeze dried ampoule of a homogeneous laboratory strain of type 4 S. pneumoniae strain NCTC 11886 was obtained from the National Collection of Type Strains. The ampoule was opened and the cultured re suspended with 0.5 ml of tryptic soy broth (0.5% glucose, 5% blood). The suspension was subcultured into 10 ml tryptic soy broth (0.5% glucose, 5% blood) and incubated statically overnight at 37° C. This culture was streaked on to 5% blood agar plates to check for contaminants and confirm viability and on to blood agar slopes and the rest of the culture was used to make 20% glycerol stocks. The slopes were sent to the Public Health Laboratory Service where the type 4 serotype was confirmed.

A glycerol stock of NCTC 11886 was streaked on a 5% blood agar plate and incubated overnight in a CO₂ gas jar at 37° C. Fresh streaks were made and optochin sensitivity was confirmed.

Pneumococcal Challenge

A standard inoculum of type 4 S. pneumoniae was prepared and frozen down by passaging a culture of pneumococcus 1× through mice, harvesting from the blood of infected animals, and grown up to a predetermined viable count of around 10⁹ cfu/ml in broth before freezing down. The preparation is set out below as per the flow chart.

An aliquot of standard inoculum was diluted 500× in PBS and used to inoculate the mice.

Mice were lightly anaesthetised using halothane and then a dose of 1.4×10⁵ cfu of pneumococcus was applied to the nose of each mouse. The uptake was facilitated by the normal breathing of the mouse, which was left to recover on its back.

S. pneumoniae Vaccine Trials

Vaccine trials in mice were carried out by the administration of DNA to 6 week old CBA/ca mice (Harlan, UK). Mice to be vaccinated were divided into groups of six and each group was immunised with recombinant pcDNA3.1+ plasmid DNA containing a specific target-gene sequence of interest. A total of 100 μg of DNA in Dulbecco's PBS (Sigma) was injected intramuscularly into the tibialis anterior muscle of both legs (50 μl in each leg). A boost was carried using the same procedure 4 weeks later. For comparison, control groups were included in all vaccine trials. These control groups were either unvaccinated animals or those administered with non-recombinant pcDNA3.1+ DNA (sham vaccinated) only, using the same time course described above. 3 weeks after the second immunisation, all mice groups were challenged intra-nasally with a lethal dose of S. pneumoniae serotype 4 (strain NCTC 11886). The number of bacteria administered was monitored by plating serial dilutions of the inoculum on 5% blood agar plates. A problem with intranasal immunisations is that in some mice the inoculum bubbles out of the nostrils, this has been noted in results table and taken account of in calculations. A less obvious problem is that a certain amount of the inoculum for each mouse may be swallowed. It is assumed that this amount will be the same for each mouse and will average out over the course of innoculations. However, the sample sizes that have been used are small and this problem may have significant effects in some experiments. All mice remaining after the challenge were killed 3 or 4 days after infection. During the infection process, challenged mice were monitored for the development of symptoms associated with the onset of S. pneumoniae induced-disease. Typical symptoms in an appropriate order included piloerection, an increasingly hunched posture, discharge from eyes, increased lethargy and reluctance to move. The latter symptoms usually coincided with the development of a moribund state at which stage the mice were culled to prevent further suffering. These mice were deemed to be very close to death, and the time of culling was used to determine a survival time for statistical analysis. Where mice were found dead, the survival time was taken as the last time point when the mouse was monitored alive.

Interpretation of Results

A positive result was taken as any DNA sequence that was cloned and used in challenge experiments as described above which gave protection against that challenge. Protection was taken as those DNA sequences that gave statistically significant protection (to a 95% confidence level (p<0.05)) and also those which were marginal or close to significant using Mann-Whitney or which show some protective features for example there were one or more outlying mice or because the time to the first death was prolonged. It is acceptable to allow marginal or non-significant results to be considered as potential positives when it is considered that the clarity of some of the results may be clouded by the problems associated with the administration of intranasal infections.

Results for vaccine trials 2, 7 and 8 (see FIG. 1)
	Mean survival times (hours)
Mouse	Unvacc	ID210	Unvacc	4172.5	Unvacc	ID211	4197.4	4122.1	4126.7
number	control (2)	(2)	control (7)	(7)	control (8)	(8)	(8)	(8)	(8)
1	49.0	55.0	59.6	72.6	45.1	102.3T	60.1	50.6	60.0
2	51.0	46.5	47.2	67.9	50.8	55.5	54.9	77.2	60.0
3	49.0	49.0	59.6	54.4	60.4	60.6*	68.4	60.3	54.8
4	55.0	59.0	70.9	75.3	55.2	45.3	60.1	50.6	52.6
5	49.0	55.0	68.6*	70.9	45.1	55.5	54.9	50.6*	54.8
6	49.0	49.0	76.0	75.3	45.1	102.3T	52.7	44.9	60
Mean	50.3	52.3	63.6	69.4	50.2	70.2	58.5	55.7	57.0
sd	2.4	4.8	10.3	7.9	6.4	25.3	5.7	11.6	3.4
p value	—	0.3333	—	0.2104	—	0.0215	0.0621	0.4038	0.0833
1
*bubbled when dosed so may not have received full inoculum.
T - terminated at end of experiment having no symptoms of infection.
Numbers in brackets - survival times disregarded assuming incomplete dosing
p value 1 refers to significance tests compared to unvaccinated controls
Statistical Analyses.
Trial 2 - The group vaccinated with ID210 also had a longer mean survival time than the unvaccinated controls but the results are not statistically significant.
Trial 7 - The group vaccinated with 4172.5 showed much greater survival times than unvaccinated controls although the differences were not statistically significant.
Trial 8 - The group vaccinated with ID211 survived significantly longer than unvaccinated controls. 4197.4, 4122.1 and 4126.7 vaccinated groups showed longer mean survival times than the unvaccinated group but the results were not statistically significant. The 4197.4 and 4126.7 groups also showed a prolonged time to the first death and the 4122.1 group showed 1 outlying result.

Results of pneumococcal challenge DNA vaccination trials 9-11 (see FIG. 2)
	Mean survival times (hours)
	Unvacc			Unvacc				Unvacc
Mouse	control	4188.11	ID209	control	pcDNA3.1+	ID215	4170.4	control	pcDNA3.1+	4193.1
number	(9)	(9)	(9)	(10)	(10)	(10)	(10)	(11)	(11)	(11)
1	(98.5)T	69.4	60.2	68.4	58.6	79.2	68.1	60.0	53.2	54.8
2	53.4	53.7	60.2	59.0	58.6	54.2	58.6	50.0	50.4	54.8
3	53.4	51.2	60.2	59.0	50.8	(103.2)*T	50.9	60.0	55.4	68.7*
4	53.4	75.0	(98.0)*T	45.1*	58.6	58.8	72.1	55.0	60.6	54.8
5	70.8	51.2	60.2	68.4	46.5	68.3	68.1	60.0	50.4	68.7
6	53.4	61.2	52.9	59.0	48.9	58.8	54.0	50.0	60.6	68.7*
Mean	56.9	60.3	58.8	59.8	53.6	63.9	62.0	55.8	55.1	61.7
Sd	7.8	10.0	3.3	8.5	5.6	10.0	8.7	5.0	4.6	7.6
p value	—	0.3894	0.2519	—	0.0307	<30.0	<39.0	—	—	0.1837
1
p value	—	—	—	—	—	0.0168	0.0316	—	—	0.0829
2
*bubbled when dosed so may not have received full inoculum.
T - terminated at end of experiment having no symptoms of infection.
Numbers in brackets - survival times disregarded assuming incomplete dosing
p value 1 refers to significance tests compared to unvaccinated controls
p value 2 refers to significance tests compared to pcDNA3.1+ vaccinated controls
Statistical Analyses.
Trial 9 - Although not statistically significant the groups vaccinated with 4188.11 and ID209 did have noticeably higher mean survival times than unvaccinated controls.
Trial 10 - The unvaccinated control group survived for a significantly longer period than the pcDNA3.1+ vaccinated group. The groups vaccinated with ID215 and 4170.4 showed statistically significant longer survival times compared to the sham vaccinated group (p = 0.0168 and 0.0316) but not compared to the unvaccinated group.
Trial 11 - The group vaccinated with 4193.1 was the most promising and survived an average of 6.5 hours longer than the pcDNA3.1+ vaccinated group and 6 hours longer than the unvaccinated group although the results were not statistically significant.

TABLE 1
4101.1
ATGGAAGAGTTAGTGACCTTAGATTGTTTGTTTGTTATTGACAGAACTAAGATTGAAGCCAATGCCAACAAGTATAGTT
TTGTGTGGAAGAAAACGACAGAGAAATTCTCCGCCAAACTTCAAGAACAGATACAGGTCTATTTTCAAGAAGAAATCAC
TCCCCTTCTGATTAAATATGCCATGTTTGATAAGAAACAAAAGAGAGGGTATAAAGAGTCAGCTAAAAACTTAGCGAAT
TGGCACTATAATGACAAGGAGGATAGCTACACACATCCTGATGGCTGGTATTATCGTTTTCACCATACCAAATATCAGA
AAACACAGACAGACTTTCAACAAGAAATCAAGGTTTACTACGCCGACGAACCTGAATCAGCCCCTCAAAAGGGACTGTA
TATGAACGAACGCTATCAAAACTTGAAAGCTAAAGAATGTCAGGCGCTTTTATCTCCCCAAGGTAGACAGATTCGCTCA
ACGCAAGATTGATGTGGAACCTGTCTTTGGGCAGATAAAGGCTTCTTTGGGTTACAAGAGATGTAATCTGAGAGGGAAG
CGTCAAGTGAGAATTGACATGGGATTGGTACTTATGGCCAATAACCTCCTAAAATATAGTAAAATGAAATAA
4101.3
ATGGGGAAAGGCCATTGGAATCGGAAAAGAGTTTATAGCATTCGTAAGTTTGCTGTGGGAGCTTGCTCAGTAATGATTG
GGACTTGTGCAGTTTTATTAGGAGGAAATATAGCTGGAGAATCTGTAGTTTATGCGGATGAAACACTTATTACTCATAC
TGCTGAGAAACCTAAAGAGGAAAAAATGATAGTAGAAGAAAAGGCTGATAAAGCTTTGGAAACTAAAAATATAGTTGAA
AGGACAGAACAAAGTGAACCTAGTTCAACTGAQGCTATTGCATCTGAGAAGAAAQAAGATGAAGCCGTAACTCCAAAAG
AGGAAAAAGTGTCTGCTAAACCGGAAGAAAAAGCTCCAAGGATAGAATCACAAGCTTCAAATCAAGAAAAACCGCTCAA
GGAAGATCCTAAAGCTGTAACAAATGAAGAAGTGAATCAAATGATTGAAGACAGGAAAGTGGATTTTAATCAAAATTGG
TACTTTAAACTCAATCCAAATTCTAAGGAAGCCATTAAACCTGATGCAGACGTATCTACGTGGAAAAAATTAGATTTAC
CGTATGACTGGAGTATCTTTAACGATTTCGATCATGAATCTCCTGCACAAAATGAAGGTGGACAGCTCAACGGTGGGGA
AGCTTGGTATCGCAAGACTTTCAAACTAGATGAAAAAGACCTCAAGAAAAATGTTCGCCTTACTTTTGATGGCGTCTAC
ATGGATTCTCAAGTTTATGTCAATGGTCAGTTAGTGGGGCATTATCCAAATGGTTATAACCAGTTCTCATATGATATCA
CCAAATACCTTCAAAAAGATGGTCGTGAGAATGTGATTGCTGTCCATGCAGTCAACAAACAGCCAAGTAGCCGTTGGTA
TTCAGGAAGTGGTATCTATCGTGATGTGACTTTACAAGTGACAGATAAGGTGCATGTTGAGAAAAATGGGACAACTATT
TTAACACCAAAACTTGAAGAACAACAACATGGCAAGGTTGAAACTCATGTGACCAGCAAAATCGTCAATACGGACGACA
AAGACCATGAACTTGTAGCCGAATATCAAATCGTTGAACGAGGTGGTCATGCTGTAACAGGCTTAGTTCGTACAGCGAG
TCGTACCTTAAAAGCACATGAATCAACAAGCCTAGATGCGATTTTAGAAGTTGAAAGACCAAACTTGGACTCTTTTTAA
ATGACAAACCTGCCTTGTACGAATTGATTACGCGTGTTACCGTGACGGTCAATTGGTTGATGCTAAGAAGGATTGTTTG
GTTACCGTTACTATCACTGGACTCCAAATGAAGGTTTCTCTTTGAATGGTGAACGTATTAAATTCCATGGAGTATCCTT
GCACCACGACCATGGGGCGCTTGGAGCAGAAGAAAACTATAAAGCAGAATATCGCCGTCTCAAACAAATGAAGGAGATG
GGAGTTAACTCCATCCGTACAACCCACAACCCTGCTAGTGAGCAAACCTTGCAAATCGCAGCAGAACTAGGTTTACTCG
TTCAGGAAGAGGCCTTTGATACGTGGTATGGTGGCAAGAAACCTTATGACTATGGACGTTTCTTTGAAAAAGATGCCAC
TCACCCAGAAGCTCGAAAAGGTGAAAAATGGTCTGATTTTGACCTACGTACCATGGTCGAAAGAGGCAAAAACAACCCT
GCTATCTTCATGTGGTCAATTGGTAATGAAATAGGTGAAGCTAATGGTGATGCCCACTCTTTAGCAACTGTTAAACGTT
TGGTTAAGGTTATCAAGGATGTTGATAAGACTCGCTATGTTACCATGGGAGCAGATAAATTCCGTTTCGGTAATGGTAG
CGGAGGGCATGAGAAAATTGCTGATGAACTCGATGCTGTTGGATTTAACTATTCTGAAGATAATTACAAGCCCTAGAGC
TAAGCATCCAAATGGTTGATTTATGGATCAGAAACATCTTCAGCTACCCGTACACGTGGAAGTTACTATCGCCCTGAAC
GTGAATTGAACATAGCAATGGACCGAGCGTAATTATGAACAGTCAGATTATGGAAATGATCGTGTGGGTTGGGGGAAAA
CAGCAACCGCTTCATGGACTTTTGACCGTGACAACGCTGGCTATGCTGGACAGTATCGGACAGGTACGGACTATATTGG
TGAACCTACACCATGGCACAACCAAAATCAAACTCCTGTTAAGAGCTCTTACTTGGTATCGTAGATACAGCCGGCATTC
CAAAACATGACTTCTATCTCTACCAAAGCCAATGGGTTCTGTTAAGAAGAAACCGATGGTACACCTTCCTCACTGGAAC
TGGGAAAACAAAGAATTAGCATCCAAAGTAGCTGACTCAGAAGGTAAGATTCCAGTTCGTGCTTATTCGAATGCTTCTA
GTGTAGAATTGTTCTTGAATGGAAAATCTCTGGTCTTAAGACTTTCAATAAAAAACAAACCAGCGATGGGCGGACTTAC
CAAGAAGGTGCAAATGCTAATGAATATCTTGAATGGAAAGTTGCCTATCAACCAGGTACCTTGGAAGCAATTGCTCGTG
ATGAATCTGGCAAGGAAATTGCTCGAGATAAGATTACGACTGCTGGTAAGCCAGCGGCAGTTCGTCTTATTAAGGAAGA
CCATGCGATTGCAGCAGATGGAAAAGACTTGACTTACATCTACTATGAAATTGTTGACAGCCAGGGGAATGTGGTTCCA
ACTGCTAATAATCTGGTTCGCTTCCAATTGCATGGCCAAGGTCAACTGGTCGGTGTAGATAACGGAGAACAAGCCAGCC
GTGAACGCTATAAGGCGCAAGCAGATGGTTCTTGGATTCGTAAGCATTTAATGGTAAAGGTGTTGCCATTGTCAAATCA
ACTGAACAAGCAGGGAAATTCACCCTGACTGCCCACTCTGATCTCTGAAATCGAACCAAGTCACTGTCTTTACTGGTAA
GAAAGAAGGACAAGAGAAGACTGTTGGGGACAGAAGTGCCAAAAAGTACAGACCATTATTGGAGAGGCACCTGAAATGC
CTACCACGTTCCGTTTGTATACAGTGATGGTAGCCGTGCAGAACGTCCTGTAACCTGGTCTTCAGTAGATGTGAGCAAG
CCGGTATTGTAACGGTGAAAGGTATGGCTGACGGACGAGAAGTAGAAGCTCGTGTAGAAGTGATTGCTCTTAAATCAGA
GCTACCAGTTGTGAAACGTATTGCTCCAAATACTGACTTGAATTCTGTAGACAAATCGTTTCCTATGTTTTGATTGATT
GATGGAAGTGTTGAAGAGTATGAAGTGGACAAGTGGGAGATTGCCGAAGAAGATAAAGCTAAGTTAGCAATTCCAGGTT
CTCGTATTCAAGCGACCGGTTATTTAGAAGGTCAACCAATTCATGCAACCCTTGTGGTAGAAGAAGGCAATCCTGCGGC
ACCGCAGTACCAACTGTAACGGTTGGTGGTGAGGCAGTAACAGGTCTTACTAGTCAAAAACCAATGCAATACCGCACTC
TTGCTTATGGAGCTAAGTTGCCAGAAGTCACAGCAAGTGCTAAAAATGCAGCTGTTACAGTTCTTCAAGCAAGCGCAGC
AAACGGCATGCGTGCGAGCATCTTTATTCAGCCTAAAGATGGTGGCCCTCTTCAAACCTATGCAATTCAATTCCTTGAA
GAAGCGCCAAAAATTGCTCACTTGAGCTTGCAAGTGGAAAAAGCTGACAGTCTCAAAGAAGACCAAACTGTCAAATTGT
CGGTTCGAGCTCACTATCAAGATGGAACGCAAGCTGTATTACCAGCTGATAAAGTAACCTTCTCTACAAGTGGTGAAGG
GGAAGTCGCAATTCGTAAAGGAATGCTTGAGTTGCATAAGCCAGGAGCAGTCACTCTGAACGCTGAATATGAGGGAGCT
AAAGACCAAGTTGAACTCACTATCCAAGCCAATACTGAGAAGAAGATTGCGCAATCCATCCGTCCTGTAAATGTAGTGA
CAGATTTGCATCAGGAACCAAGTCTTCCAGCAACAGTAACAGTTGAGTATGACAAAGGTTCCCTAAAACTCATAAAGTC
ACTTGGCAAGCTATTCCGAAAGAAAAACTAGACTCCTATCAAACATTTGAAGTACTAGGTAAAGTTGAAGGAATTGACC
TTGAAGCGCGTGCAAAAGTCTCTGTAGAAGGTATCGTTTCAGTTGAAGAAGTCAGTGTGACAACTCCAATCGCAGAAGC
ACCACAATTACCAGAAAGTGTTCGGACATATGATTCAAATGGTCACGTTTCATCAGCTAAGGTTGCATGGGATGCGATT
CGTCCAGAGCAATACGCTAAGGAAGGTGTCTTTACAGTTAATGGTCGCTTAGAAGGTACGCAATTAACAACTAAACTTC
ATGTTCGCGTATCTGCTCAAACTGAGCAAGGTGCAAACATTTCTGACCAATGGACCGGTTCAGAATTGCCACTTGCCTT
TGCTTCAGACTCAAATCCAAGCGACCCAGTTTCAAATGTTAATGACAAGCTCATTTCCTACAATAACCAACCAGCCAAT
CGTTGGACAAACTGGAATCGTACTAATCCAGAAGCTTCAGTCGGTGTTCTGTTTGGAGATTCAGGTATCTTGAGCAAAC
GCTCCGTTGATAATCTAAGTGTCGGATTCCATGAAGACCATGGAGTTGGTGTACCGAAGTCTTATGTGATTGAGTATTA
TGTTGGTAAGACTGTCCCAACAGCTCCTAAAAACCCTAGTTTTGTTGGTAATGAGGACCATGTCTTTAATGATTCTGCC
AACTGGAAACCAGTTACTAATCTAAAAGCCCCTGCTCAACTCAAGGCTGGAGAAATGAACCACTTTAGCTTTGATAAAG
TTGAAACCTATGCTGTTCGTATTCGCATGGTTAAAGCAGATAACAAGCGTGGAACGTCTATCACAGAGGTACAAATCTG
CGAACAAGTTGCGGCAGCCAAGCAAGGACAAACAAGAATCCAAGTTGACGGCAAAGACTTAGCAAACTTCAACCCTGAT
TTGACAGACTACTACCTTGAGTCTGTAGATGGAAAAGTTCCGGCAGTCACAGCAAGTGTAGCAACAATGGTCTCGCTAC
CGTCGTCCAAGCGTTCGTGAAGGTGAGCCAGTTCGTGTCATCGCGAAAGCTGAAAATGGCGACATCTTAGGAGAATACC
GTCTGCACTTCACTAAGGATAAGAGCTTACTTTCTCATAAACCAGTTGCTGCGGTTAAACAAGCTCGCTTGCTACAAGT
AGGTCAAGCACTTGAATTGCCGACTAAGGTTCCAGTTTACTTCACAGGTAAAGACGGCTACGAAACAAAAGACCTGACA
GTTGAATGGGAAGAAGTTCCAGCGGAAAATCTGACAAAAGCAGGTCAATTTACTGTTCGAGGCCGTGTCCTTGGTAGTA
ACCTTGTTGCTGAGATCACTGTACGAGTGACAGACAAACTTGGTGAGACTCTTTCAGATAACCCTAACTATGATGAAAA
CAGTAACCAGGCCTTTGCTTCAGCAACCAATGATATTGACAAAAACTCTCATGACCGCGTTGACTATCTCAATGACGGA
GATCATTCAGAAAATCGTCGTTGGACAAACTGGTCACCAACACCATCTTCTAATCCAGAAGTATCAGCGGGTGTGATTT
TCCGTGAAAATGGTAAGATTGTAGAACGGACTGTTACACAAGGAAAAGTTCAGTTCTTTGCAGATAGTGGTACGGATGC
ACCATCTAAACTCGTTTTAGAACGCTATGTCGGTCCAGAGTTTGAAGTGCCAACCTACTATTCAAACTACCAAGCCTAC
GACGCAGACCATCCATTCAACAATCCAGAAAATTGGGAAGCTGTTCCTTATCGTGCGGATAAAGACATTGCAGCTGGTG
ATGAAATCAACGTAACATTTAAAGCTATCAAAGCCAAAGCTATGAGATGGCGTATGGAGCGTAAAGCAGATAAGAGCGG
TGTTGCGATGATTGAGATGACCTTCCTTGCACCAAGTGAATTGCCTCAAGAAAGCACTCAATCAAAGATTCTTGTAGAT
GGAAAAGAACTTGCTGATTTCGCTGAAAATCGTCAAGACTATCAAATTACCTATAAAGGTCAACGGCCAAAAGTCTCAG
TTGAAGAAAACAATCAAGTAGCTTCAACTGTGGTAGATAGTGGAGAAGATAGCTTTCCAGTACTTGTTCGCCTCGTTTC
AGAAGTGGAAAACAAGTCAAGGAATACCGTATCCACTTGACTAAGGAAAAACCAGTTTCTGAGAAGACAGTTGCTGCTG
TACAAGAAGATCTTCCAAAAATCGAATTTGTTGAAAAAGATTTGGCATACAAGACAGTTGAGAAAAAAGATTCAACACT
GTATCTAGGTGAAACTCGTGTAGAACAAGAAGGAAAAGTTGGAAAAGAACGTATCTTTACAGCGATTAATCCTGATGGA
AGTAAGGAAGAAAAACTCCGTGAAGTGGTAGAAGTTCCGACAGACCGCATCGTCTTGGTTGGAACCAAACCAGTAGCTC
AAGAAGCTAAAAAACCACAAGTGTCAGAAAAAGCAGATACAAAACCAATTGATTCAAGTGAAGCTAGTCAAACTAATAA
AGCCCAGTTACCAAGTACAGGTAGTGCGGCAAGCCAAGCAGCAGTAGCAGCAGGTTTAACTCTTCTAGGTTTGAGTGCA
GGATTAGTAGTTACTAAAGGTAAAAAAGAAGACTAG
4101.5
ATGGATGCAATCTTTGACCTAATCGGAAAGGTTTTCAATCCCATCTTAGAAATGGGTGGACCTGTCATCATGTTAATCA
TTTTGACAGTATTGGCTTTACTTTTTTGGAGTGAAATTCTCCAAAGCGCTTGAAGGTGGTATCAAACTTGCCATCGCTC
TTACAGGTATCGGTGCTATCATCGGTATGCTAAACACTGCTTTCTCAGCATCACTAGCAAAATTCGTTGAAAACACTGG
TATCCAATTGAGTATTACCGACGTTGGTTGGGCACCACTTGCTACAATCACTTGGGGTTCTGCTTGGACACTATACTTC
TTGCTCATCATGTTGATTGTCAACATAGTGATGCTAGCTATGAAGAAAACAGATACACTTGATGTCGATATCTTTGATA
TCTGGCACTTGTCTATCACAGGTCTCTTGATTAAATGGTATGCTGATAACAATGGTGTGAGTCAAGGGGTTTCACTCTT
TATTGCTACAGCAGCTATCGTCCTTGTCGGTGTGTTGAAAATTATCAACTCTGACTTGATGAAACCTACATTTGATGAC
CTTCTTAACGCCCCAAGTTCATCACCAATGACATCAACTCACATGAACTACATGATGAACCCAGTTATCATGGTTTTGG
ATAAGATTTTTGAAAAATTCTTCCCAGGCCTTGATAAATATGACTTTGATGCTGCTAAATTGAACAAGAAAATCGGTTT
CTGGGGATCTAAATTCTTCATCGGTTTCATCCTTGGTATCGTTATCGGTATTATGGGAACTCCACATCCAATTGCAGGT
GTTGCAGATGCAGATAAATGGCGTCTTGTTATCAAAGGATGGTTGTCTCTTGGTTTGACTGCCGGTGTATCTTTGGAAC
TCTTCTCACTTATCGGTTCATGGTTCATCGCAGCCGTAGAACCACTATCACAAGGTATTACAAACGTTGCTACTAAACG
TCTTCAAGGACGTAAATTCAATATCGGTCTTGACTGGCCATTCATCGCTGGTCGTGCTGAAATCTGGGCTTGTGCCAAC
GTACTTGCACCAATCATGTTGATTGAAGCAGTGCTTCTTTCAAAAGTTGGAAATGGTATCTTGCCACTTGCAGGTATCA
TCGCTATGGGTGTTACTCCAGCTCTCTTGGTTGTAACTCGTGGTAAATTGCTCCGTATGATTATCTTCGGAACACTCTT
GTTGCCACTCTTCCTTCTTTCAGGTACACTTATTGCACCATTTGCAACAGAACTTGCTAAAGGTGTAGGTGCCTTCCCA
GAAGGTGTGAGCCAAACTCAATTGATTACTCACTCTACTCTTGAAGGACCAATCGAAAAACTTCTTGGTTGGACAATTG
GTAACACTACAACTGGTGATATCAAAGCAATCCTTGGTGCAGTAGTCTTCCTTGTATTCTATATCGGTATCTTTGCTTG
GTACAGAAAACAAATGATCAAACGTAACGAAGACTACGCAGCAAAAGCAAAATAA
4102.1
ATGAAGATTATGAAAAAAAAATATTGGACTTTAGCGATATTATTCTTTTGTTTGTTCAATAATTCTGTTACTGCTCAAG
AAATACCTAAAAATCTTGATGGCAATATAACTCACACTCAGACTAGCGAAAGTTTTTCTGAATCTGATGAAAAACACGT
TGACTATTCTAATAAAAATCAAGAAGAAGTAGACCAAAATAAATTTCGTATTCAAATCGATAAGACAGAATTATTTGTA
ACAACAGATAAACATTTAGAAAAAAACTGTTGTAAATTGGAACTTGAACCACAAATAAATAACGATATTGTTAACTCTG
AAAGTAATAATTTACTAGGCGAAGATAATTTAGATAATAAAATTAAGGAAAATGTTTCTCATCTAGATAATAGAGGAGG
AAATATAGAGCATGACAAAGATAACTTAGAATCGTCGATTGTAAGAAAATATGAATGGGATATAGATAAAGTTACTGGT
GGAGGCGAAAGTTATAAATTATATTCTAAAAGTAATTCTAAAGTTTCAATTGCTATTTTAGATTCAGGAGTCGATTTAC
AAAATACTGGATTACTGAAAAATCTTTCAAATCACTCAAAAAACTATGTCCCCAATAAAGGATATTTAGGAAAAGAGGA
GGGAGAGGAAGGAATAATATCAGATATTCAAGATAGATTAGGTCATGGTACGGCTGTTGTAGCTCAAATTGTAGGGGAT
GACAATATTAATGGAGTAAATCCTCACGTTAATATTAACGTCTATAGAATATTTGGTAAGTCGTCAGCTAGTCCAGATT
GGATTGTAAAAGCAATTTTTGATGCTGTAGATGATGGCAATGATATTATCAATCTTAGTACTGGACAATATTTAATGAT
TGATGGAGAATATGAGGACGGAACAAATGATTTTGAAACATTTTTGAAGTATAAAAAGGCTATTGATTACGCGAATCAA
AAAGGAGTAATTAGTAGCTGCATTAGGGAATGACTCCCTAAATGTATCAAATCAGTCAGATTTATTGAAACTTATTAGT
TCACGCAAAAAAGTAAGAAAACCAGGATTAGTAGTTGATGTTCCAAGTTATTTCTCATCTACAATTTCGGTCGGAGGCA
TAGATCGCTTAGGTAATTATCAGATTAGCAATAAAGGGGATTCTGATGCAATATATGCGCCTGCAGGCTCAACATTATC
TCTTTCAGAATTAGGACTTAATAACTTTATTAATGCAGAAAAATATAAAGAAGATTGGATTTTTTCGGCAACACTAGGA
GGATATACGTATCTTTATGGAAACTCATTTGCTGCTCCTAAAGTTTCTGGTGCGATTGCAATGATTATTGATAAATACA
AATTAAAGATCAGCCCTATAATTATATGTTGTAAAAAAATTCTGGAAGAAACATTACCAGTAA
4106.1
ATGAAGAAAACATGGAAAGTGTTTTTAACGCTTGTAACAGCTCTTGTAGCTGTTGTGCTTGTGGCCTGTGGTCAAGGAA
CTGCTTCTAAAGACAACAAAGAGGCAGAACTTAAGAAGGTTGACTTTATCCTAGACTGGACACCAAATACCAACCACAC
AGGGTTTATGTTGCCAAGGAAAAAGGTTATTTCAAAGAAGCTGGAGTGGATGTTGATTTGAAATTGCCACCAGAAGAAA
GTTCTTCTGACTTGGTTATCAACGGAAAGGCACCATTTGCAGTGTATTTCCAAGACTACATGGCTAAGAAATTGGAAAA
AGGAGCAGGAATCACTGCCGTTGCAGCTATTGTTGAACACAATACATCAGGAATCATCTCTCGTAAATCTGATAATGTA
AGCAGTCCAAAAGACTTGGTTGGTAAGAAATATGGGACATGGAATGACCCAACTGAACTTGCTATGTTGAAAACCTTGG
TAGAATCTCAAGGTGGAGACTTTGAGAAGGTTGAAAAAGTACCAAATAACGACTCAAACTCAATCACACCGATTGCCAA
TGGCGTCTTTGATACTGCTTGGATTTACTACGGTTGGGATGGTATCCTTGCTAAATCTCAAGGTGTAGATGCTAACTTC
ATGTACTTGAAAGACTATGTCAAGGAGTTTGACTACTATTCACCAGTTATCATCGCAAACAACGACTATCTGAAAGATA
ACAAAGAAGAAGCTCGCAAAGTCATCCAAGCCATCAAAAAAGGCTACCAATATGCCATGGAACATCCAGAAGAAGCTGC
AGATATTCTCATCAAGAATGCACCTGAACTCAAGGAAAAACGTGACTTTGTCATCGAATCTCAAAAATACTTGTCAAAA
GAATACGCAAGCGACAAGGAAAAATGGGGGTCAATTTGACGCAGCTCGCTGGAATGCTTTCTACAAATGGGATAAAGAA
AATGGTATCCTTAAAGAAGACTTGACAGACAAAGGCTTCACCAACGAATTTGTGAAATAA
4106.4
ATGATAAAAAATCCTAAATTATTAACCAAGTCTTTTTTAAGAAGTTTTGCAATTCTAGGTGGTGTTGGTCTAGTCATTC
ATATAGCTATTTATTTGACCTTTCCTTTTTATTATATTCAACTGGAGGGGAAAAGTTTAATGAGAGCGCAAGAGTGTTT
ACGGAGTATTTAAAGACTAAGACATCTGATGAAATTCCAAGCTTACTCCAGTCTTATTCAAAGTCCTTGACCATATCTG
CTCACCTTAAAAGAGATATTGTAGATAAGCGGCTCCCTCTTGTGCATGACTTGGATATTAAAGATGGAAAGCTATCAAA
TTATATCGTGATTAGATATGTCTGTTAGTACAGCAGATGGTAAACAGGTAACCGTGCAATTTGTTCACGGGGTGGATGT
CTACAAAGAAGCAAAGAATATTTTGCTTTTGTATCTCCCATATACATTTTTGGTTACAATTGCTTTTTCCTTTGTTTTT
TCTTATTTTTATACTAAACGCTTGCTCAATCCTCTTTTTTACATTTCAGAAGTGACTAGTAAAATGCAAGATTTGGATG
ACAATATTCGTTTTGATGAAAGTAGGAAAGATGAAGTTGGTGAAGTTGGAAAACAGATTAATGGTATGTATGAGCACTT
GTTGAAGGTTATTTATGAGTTGGAAAGTCGTAATGAGCAAATTGTAAAATTGCAAAATCAAAAGGTTTCCTTTGTCCGC
GGAGCATCACATGAGTTGAAAACCCTTTAGCCAGTCTTAGAATTATCCTAGAGAATATGCAGCATAATATTGGAGATTA
CAAAGATCATCCAAAATATATTGCAAAGAGTATAAATAAGATTGACCAGATGAGCCACTTATTAGAAGAAGTACTGGAG
TCTTCTAAATTCCAAGAGTGGACAGAGTGTCGTGAGACCTTGACTGTTAAGCCAGTTTTAGTAGATATTTTATCACGTT
ATCAAGAATTAGCTCATTCAATAGGTGTTACAATTGAAAATCAATTGACAGATGCTACCAGGGTCGTCATGAGTCTTAG
GGCATTGGATAAGGTTTTGACAAACCTGATTAGTAATGCAATTAAATATTCAGATAAAAATGGGCGTGTAATCATATCC
GAGCAAGATGGCTATCTCTCTATCAAAAATACATGTGCGCCTCTAAGTGACCAAGAACTAGAACATTTATTTGATATAT
TCTATCATTCTCAAATCGTGACAGATAAGGATGAAAGTTCCGGTTTGGGTCTTTACATTGTGAATAATATTTTAGAAAG
CTATCAAATGGATTATAGTTTTCTCCCTTATGAACACGGTATGGAATTTAAGATTAGCTTGTAG
4106.6
ATGTATTTAGGAGATTTGATGGAGAAAGCCGAGTGTGGTCAATTTTCAATACTTTCCTTTCTATTACAAGAGTCTCAGA
CGACCGTCAAGGCTGTAATGGAAGAAACAGGATTTTCAAAAGCAACCCTAACCAAATATGTCACCCTGCTCAATGACAA
GGCTTTGGATAGTGGCTTAGAGCTGGCTATTCACTCAGAAGATGAAAATCTGCGTCTGTCTATCGGTGCAGCTACCAAG
GGGAGAGATATTCGGAGCTTGTTTTTTGGAGAGTGCTGTTAAATACCAGATTTTGGTTTATCTTCTCTACCACCAACAG
TTTTTAGCCCATCAGCTGGCTCAAGAATTGGTGATTAGCGAGGCTACGCTTGGTCGTCACTTGGCTGGTTTAAATCAGA
TTTTGTCAGAATTTGATTTATCCATCCAAAATGGCCGTTGGCGAGGTCCAGAGCATCAGATTCACTATTTCTATTTCTG
TCTTTTCCGAAAGGTCTGGTCGAGTCAGGAATGGGAAGGTCACATGCAGAAACCAGAGAGAAAACAGGAGATTGCCAAT
TTAGAGGAAATCTGCGGTGCAAGTTTGTCTGCGGGGCAGAAATTGGACTTGGTTCTCTGGGCTCACATCAGTCAACAAC
GTCTTCGGGTCAATGCTTGTCAGTTTCAAGTCATAGAAGAGAAAATGCGAGGGTATTTTGACAATATCTTTTATCTTCG
TTTGCTGAGAAAGGTTCCGTCCTTTTTTGCTGGGCAACATATTCCACTAGGAGTTGAGGATGGTGAGATGATGATATTC
TTCTCTTTTCTCCTATCTCATCGCATTCTTCCTCTTCATACTATGGAGTATATTCTTGGTTTTGGAGGGCAGTTGGCAG
ATTTACTGACGCAATTGATTCAAGAAATGAAGAAGGAGGAACTATTGGGGGATTATACAGAGGACCATGTCACCTATGA
ACTCAGTCAGCTTTGTGCTCAAGTCTATCTCTATAAGGGCTATATTTTACAGGATCGCTACAAGTACCAGTTAGAGAAT
CGTCATCCATATTTACTGATGGAACATGATTTTAAAGAGACAGCAGAGGAGATTTTTCATGCTCTACCTGCTTTTCAAC
AGGGGACAGATTTAGATAAGAAGATTCTCTGGGAATGGCTCCAGTTAATCGAATATATGGCTGAAAACGGTGGCCAGCA
TATGCGGATTGGTCTGGATTTGACATCTGGTTTTCTTGTCTTTTCAAGGATGGCAGCCATTTTGAAACGGTATTTGGAA
TACAATCGTTTTATTACCATTGAAGCTTATGACCCTAGTCGGCATTATGATTTGCTGGTTACCAATAACCCGATTCATA
AGAAGGAACAGACACCAGTCTATTATTTAAAAAATGACTTGGATATGGAGGATTTGGTAGCGATTCGCCAGTTATTATT
CACTTAA
4106.7
ATGGAATTTTCAAAGAAAACACGTGAATTGTCAATTAAAAAAATGCAGGAACGTACCCTGGACCTCTTGATTATCGGTG
GAGGAATCACAGGAGCTGGTGTAGCCTTGCAGGCGGCAGCTAGCGGTCTTGAGACTGGTTTGATTGAAATGCAAGACTT
TGCAGAAGGAACATCTAGTCGTTCAACAAATTGGTTCACGGAGGACTTCGTTACCTCAAACAATTTGACGTAGAAGTGG
TCTCAGATACGGTTTCTGAACGTGCAGTGGTTCAACAAATCGCTCCACACATTCCAAAATCAGATCCAATGCTCTTACC
AGTTTACGATGAAGATGGAGCAACCTTTAGCCTCTTCCGTCTTAAAGTAGCCATGGACTTGTACGACCTCTTGGCAGGT
GTTAGCAACACACCAGCTGCGAACAAGGTTTTTGAGCAAGGATCAAGTCTTGGAACGCCAGCCAAACTTGAAGAAGGAA
GGCTTGGTAGGAGGTGGAGTGTATCTTGACTTCCGTAACAACGATGCGCGTCTCGTGATTGAAAACATCAAACGTGCCA
ACCAAGACGGTGCCCTCATTGCCAACCACGTGAAGGCAGAAGGCTTCCTCTTTGACGAAAGTGGCAAGATTACAGGTGT
TGTAGCTCGTGATCTCTTGACAGACCAAGTGTTTGAAATCAAGGCCCGTCTGGTTATTAATACAACAGGTCCTTGGAGT
GATAAAGTACGTAATTTGTCTAATAAGGGAACGCAATTCTCACAAATGCGCCCAACTAAGGGAGTTCACTTGGTAGTAG
ATTCAAGCAAAATCAAGGTTTCACAGCCAGTTTACTTCGACACAGGTTTGGGTGACGGTCGTATGGTCTTTGTTCTCCC
ACGTGAAAACAAGACTTACTTTGGTACAACTGATACAGACTACACAGGTGATTTGGAGCATCCAAAAGTAACTCAAGAA
GATGTAGATTATCTACTTGGCATTGTCAACAACCGCTTCCCAGAATCCAACATCACCATTGATGATATCGAAAGCAGCT
GGGCAGGTCTTCGTCCATTGATTGCAGGGAACAGTGCCTCTGACTATAATGGTGGAAATAACGGTACCATCAGTGATGA
AAGCTTTGACAACTTGATTGCGACTGTTGAATCTTATCTCTCCAAAGAAAAAACACGTGAAGATGTTGAGTCTGCTGTC
AGCAAGCTTGAAAGTAGCACATCTGAGAAACATTTGGATCCATCTGCAGTTTCTCGTGGGTAGCTTGGACCGTGATGAC
AATGGTCTCTTGACTCTTGCTGGTGGTAAAATCACAGACTACCGTAAGATGGCTGAAGGAGCTATGGAGCGCGTGGTTG
ACATCCTCAAAGCAGAATTTGACCGTAGCTTTAAATTGATCAATTCTAAAACTTACCCTGTTTCAGGTGGAGAATTGAA
CCCAGCAAATGTGGATTCAGAAATCGAAGCCTTTGCGCAACTTGGAGTATCACGTGGTTTGGATAGCAAGGAAGCTCAC
TATCTGGCAAATCTTTACGGTTCAAATGCACCGAAAGTCTTTGCACTTGCTCACAGCTTGGAACAAGCGCCAGGACTCA
GCTTGGCAGATACTTTGTCCCTTCACTATGCAATGCGCAATGAGTTGACTCTTAGCCCAGTTGACTTCCTTCTTCGTCG
TACCAATCACATGCTCTTTATGCGTGATAGCTTGGATAGTATCGTTGAGCCAATTTTGGATGAAATGGGACGATTCTAT
GACTGGACAGAAGAAGAAAAAGCAACTTACCGTGCTGATGTCGAAGCAGCTCTCGCTAACAACGATTTAGCAGAATTAA
AAAATTAA
4106.8
ATGATGAATGAATTATTTGGAGAATTTCTAGGGACTTTAATCCTGATTCTTCTAGGAAATGGTGTTGTTGCAGGTGTGG
TTCTTCCTAAAACCAAGAGCAATAGCTCAGGTTGGATTGTGATTACTATGGGTTGGGGGATTGCAGTTGCGGTTGCAGT
CTTTGTATCTGGCAAGCTCAGTCCAGCTTATTTAAACCCAGCTGTGACCATCGGTGTGGCCTTAAAAGGTGGTTTGCCT
TGGGCTTCCGTTTTGCCTTATATCTTAGCCCAGTTCGCAGGGGCCATGCTGGGTCAGATTTTGGTTTGGTTGCAATTCA
AACCTCACTATGAGGCAGAAGAAAATGCAGGCAATATCCTGGCAACCTTCAGTACTGGACCAGCCATCAAGGATACTGT
ATCAAACTTGATTAGCGAAATCCTTGGAACTTTTGTTTTGGTGTTGACAATCTTTGCTTTGGGTCTTTACGACTTTCAG
GCAGGTATCGGAACCTTTGCAGTGGGAACTTTGATTGTCGGTATCGGTCTATCACTAGGTGGGACAACAGGTTATGCCT
TGAACCCAGCTCGTGACCTTGGACCTCGTATCATGCACAGCATCTTGCCAATTCCAAACAAGGGAGACGGAGACTGGTC
TTACGCTTGGATTCCTGTTGTAGGCCCTGTTATCGGAGCAGCCTTGGCAGTGCTTGTATTCTCACTTTTCTAG
4106.10
ATGAAAAGGACCTGGAGGAACTCATTCGTGACAAATCTTAATACACCTTTTATGATTGGCAATATTGAGATTCCCAATC
GTACCGTTTTAGCGCCTATGGCTGGCGTGACCAACTCAGCCTTTCGTACTATCGCAAAGGAGCTCGGAGCTGGACTCGT
TGTAATGGAAATGGTCTCTGACAAGGGAATCCAATACAACAACGAAAAACCCTGCACATGCTTCATATCGATGAGGGCG
AAAACCCTGTCTCTATCCAACTTTTTGGTAGCGATGAAGACAGCCTAGCACGCGCAGCAGAATTCATCCAAGAAAACAC
CAAGACCGATATCGTCGATATCAACATGGGCTGCCCTGTCAACAAAATCGTGAAGAACGAAGCTGGTGCTATGTGGTCA
AGGATCCAGACAAGATTTACTCCATCATCAACAAGGTCCAGTCTGTCCTTGATATCCCACTTACTGTCAAAATGCGTAC
CGGCTGGGCGGACCCATCTCTTGCAGTAGAAAATGCTCTCGCTGCTGAAGCTGCAGGTGTTTCTGCCCTCGCCATGCAT
GGCCGTACCCGTGAACAAATGTATACTGGCCACGCAGACCTTGAGACCCTTTACAAGGTTGCCCAAGCTCTAACCAAGA
TTCCATTCATCGCCAACGGTGATATCCGTACTGTCCAAGAAGCCAAGCAACGCATCGAAGAAGTTGGTGCTGACGCAGT
CATGATTGGCCGAGCTGCCATGGGAAATCCTTACCTCTTCAACCAAATCAACCATTACTTTGAAACAGGAGAAATCCTA
CCTGATTTGACCTTTGAAGACAAGATGAAGATCGCCTACGAACACTTGAAACGATTGATTAACCTCAAAGGAGAAAACG
TCGCAGTTCGTGAATTCCGCGGTCTCGCTCCTCACTATCTCCGTGGAACATCTGGCGCTGCCAAACTCCGTGGAGCCAT
TTCGCAAGCCAGCACCCTGGCAGAGATTGAAACCCTCTTGCAATTGGAGAAGGCTTAA
4107.1
ATGACAAAGAAGAAAATTGAGCGTATTTCTGTAATACACCGAGAAAAGATTTTATGGCTCAAGTGGTATTTCATGCGAG
ATAAAGAACAACCTAAGTATAGTGTCCTTGAGCGTAAAATGTTTGATGCTGCTAAAAATCAAGATATGCTAGCTTATCA
AAAATACGCAACTATCAAGCAGATAACAGATATTAGGGTACAAACAAGTGAGGCTGACATTTTAGAGGCTGTAAAAGAG
GTTTATGTGTACAATCACATGAATGTTATCGGAGCTTGTCAGCGGATATTATTTATCAGTCAATCACCAGCTTATGATA
AGTTAAATAAGTGGTTTAATATCTATTCTGATTTGTATTTTAGCGTTGTACCCTTGCCCAAAATGGGGGTATATCATGA
GATGGTAGGTATCTAG
4107.2
ATGAAAAATTCCAACGAGGCTGAGATGAAATTACTTTATACTGATATTCGGACTTCTTTGACAGAAATTCTAACAAGAG
AGGCAGAAGAGCTAGTTGCAGCTGGCAAGCGGGTCTTCTACATTGCCCCCAACTCTCTTTCTTTTGAAAAGGAACGCGC
CGTGCTGGAATACTTGTCCCAGCAGGCTTCTTTTTCGATTACCGTCACGCGCTTTGCTCAAATGGCTCGCTATCTGGTC
TTGAATGATTTACCAGCTAAAACTACTCTTGATGATATCGGTCTTGGGTTGGCCTTTTACAAATGCCTTGCCGAACTCG
ATCCCAAGGACTTGCGTGTTTATGGCGCTATTAAGCAGGATCCTCAATTGATCCAGCAGTTAATTGAGCTTTACCATGA
GATGACCAAATCTCAGATGAGTTTTTTGGACTTGGAGAATTTAACAGATGAGGATAAGAGGGCGGATTTACTCTTGATT
TTTGAGAAAGTAACAGCCTATCTTAATCAAGGTCAGTTAGCCCAGGAAAGTCAGTTGTCCCATTTGATTGAGGCTATTG
AGAATGACAAGGTAAGTAGTGATTTTAATCAAATCGCCTTGGTCATTGACGGCTTTACTCGTTTTTCTGCTGAGGAAGA
GCGGGTTGTGGACTTACTTCACGGCAAAGGTGTTGAGATTGTTATCGGGGGCTTATGCTAGTAAGAAAGCCTATACCAG
TCCTTTTAGCGAGGGCAATCTCTACCAAGCCAGCGTAAAATTTCTCCATCATCTGGCTTCTAAATACCAAACGCCTGCT
CAGGACTGTTCTCAAACTCATGAGAAGATGGATAGTTTTGACAAGGCCTCTCGTTTGTTGGAGTCTTCTTATGACTTTT
CAGAACTCGCTTTGGATGTCGATGAGAAAGACCGTGAAAATTTACAAATCTGGTCTTGTTTGACGCAAAAGGAGGAGTT
GGAGCTAGTAGCCCGTAGTATTCGTCAGAAATTACATGAGAACTCAGACCTGAGCTACAAGCATTTTCGTATTCTCTTG
GGGGATGTAGCTTCTTACCAGTTATCTCTCAAAACCATTTTTGACCAGTATCAGATCCTTTTTATCTTGGTAGAAGCGA
AGCCATGGCTCATCATCCCTTGACTCAGTTTGTCGAGTCTATTTTAGCTTTAAAACGTTACCGTTTCGTCAGGAGGATT
TGATTAATCTTCTTAGAACTGATTTGTATACTGACCTCAGTCAGTCTGATATTGATGCTTTTGAGCAATATATCCGCTA
TCTTGGTATCAATGGCTTGCCAGCCTTTCAGCAAACCTTCACCAAATCCCACCATGGAAAATTTAATCTTGAGCGTTTG
AATGTCCTCCGCCTGAGAATTTTAGCACCTCTTGAAACCCTCTTTGCCAGCCGAAAACAAAAGGCTGAAAAACTCCTAC
AAAAATGGAGTGTCTTTCTAAAAGAAGGAGCTGTGACCAAGCAGTTACAAGATTTGACAACCACTTTGGAAGCTGTAGA
ACAGGAAAGACAAGCCGAAGTTTGGAAGGCTTTCTGCCATGTTTTAGAACAATTTGCGACTGTTTTTGCTGGTTCACAG
GTTAGTCTGGAAGACTTCCTAGCCTTGCTCCATTCTGGAATGAGTTTGTCCCAATACCGTACCATTCCAGCAACAGTGG
ACACTGTTCTGGTGCAGAGTTACGATTTGATTGCACCATTGACTGCTGACTTTGTCTATGCTATTGGACTAACTCAGGA
CAATTTACCAAAAATTTCTCAAAACACCAGTCTTCTGACAGATGAAGAAAGGCAAAACCTAAACCAAGCGACCGAAGAA
GGCGTTCAATTACTGATTGCCAGCAGTGAAAATCTCAAGAAAAATCGCTACACTATGCTTTCCTTGGTCAATTCTGCTC
GTAAGCAGTTGTTCTTGTCGGCTCCAAGCCTTTTTAACGAAAGTGAAAGTAAGGAATCTGCCTATCTTCAAGAGTTGAT
CCATTTTGGATTTAGGCGGAGAGAGAAGAGGATGAATCACAAAGGACTGTCTAAGGAGGATATGGGGTCCTATCACAGT
CTTTTGTCTAGTCTGGTTGCCTATCACCAGCAGGGTGAGATGAGCGATACTGAGCAAGATTTGACTTTTGTCAAGGTTC
TGTCGCGTGTCATAGGTAAAAAACTAGATCAGCAAGGTCTGGAAAATCCAGCTATCCCAACCAGTCCAAGCAGCAAGAC
CTTAGCCAAGGACACCTTGCAAGCTCTCTATCCTGCCAAACAGGAGTTTTACCTGTCTACGTCGGGTTGACAGAGTTTT
ATCGCAATGAATACAGTTATTTCCTACGCTACGTTTTAGGCTTGCAGGAGGAATTACGTTTGCATCCTGATGCCCGTAG
TCACGGGAATTTCTTGCATCGTATCTTTGAACGCGCCTTACAGTTCGGTAATGAAGATTCCTTTGACCAACGTCTAGAA
CAAGCTATTCAAGAAACCAGTCAAGAACGCGAATTTGAAGCTATTTATCAAGAAAGTTTGGAAGCCCAGTTTACCAAGG
AAGTTTTGCTTGATGTTGCACGGACAACTGGACATATTCTCCGACACAATCCAGCCATCGAAACCATCAAAGAAGAAGC
AAATTTTGGTGGAAAAGACCAAGCCTTTATTCAATTAGACAATGGACGCAGTGTCTTTGTACGAGGCAAGGTGGACCGG
ATTGACCGTTTGAAAGCTAATGGAGCGATAGGAGTAGTAGACTACAAATCCAGTCTGACTCAGTTCCAGTTTCCTCATT
TCTTTAATGGGCTCAATTCTCAGTTACCAACCTATCTTGCTGCCCTAAAAAGAGAAGGGGAGCAGAACTTTTTCGGCGC
CATGTACTTGGAAATGGCTGAACCTGTCCAATCTCTGATGGCGGTAAAAAGTCTGGCAGGAGCAGTGGTAGAAGCCAGC
AAATCTATGAAATACCAAGGGCTCTTCTTGGAAAAAGAAAGCAGTTATTTAGGCGAATTTTATAACAAAAACAAGGCTA
ATCAACTGACAGATGAGGAATTTCAGCTCCTACTGGACTACAATGCCTATCTTTACAAGAAAGCCTGCTGAGAAGATTT
TAGCAGGCCGGTTCGCCATCAATCCTTATACTGAAAATGGCAGAAGCATTGCCCCATACGTCCAGCAACATCAGGCTAT
TACAGGCTTTGAAGCCAATTACCATCTGGGCCAAGCCCGTTTCCTAGAAAAGTTGGACCTAGCTGATGGCAAGCGTCTG
GTCGGAGAAAAACTCAAGCAAGCTTGGCTTGAAAAAATAAGAGAGGAGTTGAATCGATGAGAGAGGAGTTGAATCGATGA
4107.3
ATGAAGCTTATTCCCTTTTTAAGTGAGGAGGAGATTCAAAAACTGCAAGAAGCAGAAGCAAATTCGAGCAAGGAACAGA
AGAAAACTGCCGAGCAAATCGAAGCTATCTACACTTCTGCCCAGAATATCCTGGTCTGAGCATCGGCTGGTTCTGGAAA
GACCTTTGTCATGGCAGAGCGATTCTGGACCAATTGGCGCGTGGTGTCGAAATTTCTCAACTCTTTATCTCAACCTTTA
CCGTCAAGGCTGCAACTGAACTTAAAGAACGTTTAGAGAAAAAAATCAGCAAGAAAATCCAAGAAACAGATGATGTCGA
CCTCAAACAACACTTGGGTCGCCAGTTGGCAGACCTACCCAACGCTGCCATTGGAACCATGGATTCTTTCACACAAAAA
TTCCTTGGCAAACATGGTTATCTGCTTGATATTGCACCTAATTTCCGTATTTTACAAAACCAAAGCGAGCAACTTATTC
TCGAAAACGAAGTCTTTCATGAGGTCTTTGAAGCGCATTACCAAGGTAAACAGAAAGAGACCTTTAGTCATTTGCTGAA
AAACTTTGCTGGGCGTGGCAAGGACGAACGGGGTCTGCGCCAGCAGGTCTATAAAATCTATGACTTCCTCCAATCCACC
AGTAATCCTCAAAAGTGGCTGAGTGAATCTTTCCTCAAAGGATTTGAGAAAGCTGATTTTACCAGTGAAAAAGAAAAAC
TGACCGAGCAAATCAAACAAGCCCTTTGGGATTTGGAAAGCTTTTTCCGTTACCATCTGGATAACGATGCCAAGGAGTT
TGCAAAGGCTGCCTATTTAGAAAATGTTCAGTTAATTCTGGATGAAATTGGCTCCCTAAATCAGGAGTCCGATAGTCAG
GCTTATCAGGCAGTGCTTGCGCGTGTTGTCGCCATCTCTAAGGAGAAAAACGGTCGAGCTCTGACTAATGCCAGCCGTA
AGGCTGATTTGAAGCCCCTGGCTGATGCCTACAACGAAGAGAGAAAGACCCAGTTTGCTAAACTAGGACAATTATCAGA
CCAGATAGCGATTCTCGACTATCAAGAACGTATCATGGAGACACTTGGAAACTAGCTAAAACCTTCCAATCTTTCATGA
GCGATTTTGTAGAGGCTTATCGTCAGAGAAAACGACAGGAAAATGCCTTCGAATTCGCTGATATCAGCCATTACACCAT
TGAGATTTTAGAGAATTTCCCACAAGTTCGTGAGTCTTATCAGGAGCGCTTCCATGAAGTCATGGTCGATGAGTATCAG
GATACCAACCATATTCAAGAACGGATGCTGGAATTGTTGTCTAATGGCCACAATCGCTTTATGGTGGGAGATATCAAGC
AATCCATCTATCGTTTCCGTCAGGCAGACCCGCAGTTTTCAATGAGAAATTCCAACGCTATGCGCAAAATCCCCAAGAA
GGCAGGCTCATTATCCTCAAGGAAAATTTCCGTAGTAGTTCAGAAGTGCTGTCAGCAACCAATGATGTCTTTGAACGTC
TCATGGACCAAGAGGTCGGCGAAATCAACTATGATAACAAGCACCAGCTTGTTTTTGCCAATACCAAACTGACTCCCAA
TCCAGACAACAAGGCAGCATTTCTCCTCTACGACAAGGACGATACAGGTGAGGAAGAAGAGAGTCAAACAGAAACGAAA
CTAACAGGCGAAATGCGCTTAGTTATCAAGGAGATTCTGAAACTTCATCAAGAAAAAGGTGTTGCCTTTAAGGAAATTG
CCCTTCTGACCTCCAGCCGCAGTCGTAATGACCAGATTCTCCTCGCCCTGTCTGAGTACGGAATTCCTGTCAAAACTGA
CGGAGAGCAAAACAATTATCTCCAATCCCTAGAAGTGCAAGTCATGCTAGACACTCTTCGTGTCATTCACAATCCCCTG
CAAGACTACGCCTGGTTGCCCTTATGAAGTCTCCAATGTTTGGTTTTGATGAGGATGAGCTAGCACGTTTGTCCCTTCA
GAAAGCAGAGGATAAAGTCCACGAAAATCTCTATGAGAAACTGGTCAATGCACAAAAAATGGCAAGTAGTCAAAAAGGC
TTGATTCACACAGCTCTAGCTGAAAAACTAAAGCAATTCATGGATATCCTAGCTTCTTGGCGCTTGTATGCCAAAACCC
ACTCTCTCTATGACTTGATTTGGAAGATTTACAACGACCGTTTTTATTATGACTATGTTGGGGCTTTGCCGAATGGTCC
TGCTAGGCAGGCCAATCTCTATGCCCTAGCACTGCGTGCTGATCAATGAAAAGAGCAATTTCAAAGGTTTGTCGCGTTT
TATTCGTATGATTGACCAAGTCTTAGAAGCCCAGCACGATTTGGCAAGCGTGGCCGTCGCACCGCCAAAAGATGCAGTA
GAGCTCATGACCATCCACAAGAGTAAAGGGCTGGAGTTTCCTTACGTCTTTATCCTCAATATGGATCAAGATTTCAACA
AGCAAGACTCTATGTCAGAAGTCATTCTCAGTCGTCAGAATGGTCTTGGTGTCAAATATATTGCCAAGATGGAGACAGG
GGCAGTAGAAGACCACTATCCTAAAACCATCAAACTCTCCATTCCTAGTCTGACCTATAGGCAGAACGAAGAGGAATTA
CAGCTAGCAAGCTATTCTGAGCAGATGCGTTTGCTGTATGTTGCTATGACGCGGGCTGAGAAAAAGCTCTATCTTGTCG
GCAAGGGTTCTCGTGAAAAGCTGGAATCCAAGGAATACCCAGCAGCCAAAAATGGGAAACTAAATAGCAATACTAGACT
GCAAGCACGGAATTTCCAAGATTGGCTTTGGGCTATCAGTAAAGTGTTTACTAAGGACAAGCTCAACTTTAGTTATCGT
TTTATTGGCGAAGATCAGTTGACCAGAGAAGCTATCGGAGAGTTGGAAACCAAGAGTCCTCTCCAAGATAGCTCCCAAG
CAGACAATCGTCAGTCAGATACCATCAAAGAAGCTCGGAAATGCTGAAGGAGGTGGAAGTTTATAATACTCTTCACCGC
GCAGCTATTGAACTTCCTAGTGTTCAAACCCCAAGTCAAATCAAGAAATTCTACGAACCAGTTATGGATATGGAAGGTG
TCGAGATTGCTGGTCAAGGTCAGTCAGTAGGCAAGAAAATCAGCTTCGATTTGCCAGATTTTTCAACCAAAGAAAAGGT
AACTGGAGCTGAGATTGGTAGTGCTACTCACGAACTCATGCAGAGAATTGACCTCAGCCAGCAACTAACCCTTGCTAGC
CTAACAGAACACTCAAACAAGTTCAAACTAGCCAAGCTGTCAGAGACAAGATCAATCTGATAAAATTCTTGCTTTCTTT
GACACAGTACTCGGTCAGGAAATTCTTGCTAATACCGACCATCTTTATCGCGAGCAACCTTTCTCCATGCTCAAACGAG
ACCAAAAGAGTCAGGAAGACTTTGTTGTCCGTGGTATCCTTGATGGCTATCTGCTTTACGAAAACAAAATTGTTCTGTT
CGACTACAAGACAGACCGCTATGATGAACCAAGTCAACTCGTAGACCGCTATCGTGGTCAGTTAGCTCTATACGAAGAG
GCTTTATCACGAGCCTATTCGATTGAAAATATTGAAAAATACTTGATTTTACTCGGTAAAGACGAGGTTCAAGTTGTAA
AAGTATAA
4109.1
ATGGAACTTGCTCGCCATGCTGAAAGCTTGGGAGTAGATGCTATTGCAACGATTCCACCAATTTATTTCCGCTTGCCAG
AATACTCAGTTGCCAAATACTGGAACGATATCAGTTCTGCAGCTCCAAACACAGACTACGTGATTTACAACATTCCTCA
ATTGGCAGGGGTTGCTTTGACTCCAAGCCTTTACACAGAAATGTTGAAAAATCCTCGTGTTATCGGTGTGAAGAACTCT
TCTATGCCAGTTCAAGATATCCAAACCTTTGTCAGCCTTGGTGGAGAAGACCATATCGTCTTTAATGGTCCTGATGAGC
AGCAGTTCCTAGGAGGACGCCTCATGGGGGCTAGGGCTGGTATCGGTGGTACTTATGGTGCTATGCCAGAACTCTTCTT
GAAACTCAATCAGTTGATTGCGGATAAGGACCTAGAAACAGCGCGTGAATTGCAGTATGCTATCAACGCAATCATTGGT
AAACTCACTTCTGCTCATGGAAATATGTACGGTGTCATCAAAGAAGTCTTGAAAATCAATGAAGGCTTGAATATTGGAT
CTGTTCGTTCACCATTGACACCAGTGACTGAAGAAGATCGTCCAGTTGTAGAAGCGGCTGCTGCCTTGATTCGTGAAAC
CAAGGAGCGCTTCCTCTAA
4110.2
ATGTATAAGACAAAGTGTTTACGAGAGAAGTTAGTATTATTTTTAAAAATTTTCTTCCCAATCCTGATCTACCAATTTG
CCAATTATTCTGCCTCTTTTGTTGATACTGCAATGACAGGTCAATACAACACTATGGACTTGGCTGGTGTATCTATGGC
AACCAGTATCTGGAATCCTTTCTTTACATTTCTAACAGGGATTGTGTCAGCCTTGGTGCCTATCATTGGTCACCATCTT
GGTCGAGGCAAAAAGGAAGAAGTTGCGTCTGATTTTTACCAATTTATTTATTTGGCCTTGGGCCTATCTGTGGTCTTGC
TGGGGATGGTACTTTTCTTGGCACCAATAATCTTGAATCATATTGGGTTAGAAGCAGCAGTAGCGGCAGTAGCGGTTCG
CTATCTTTGGTTTTTATCTATCGGGATTATCCCCTTGTTGCTCTTTAGCGTCATTCGTTCCTTGCTGGATTCGCTGGGC
TTGACCAAACTGTCCATGTACCTCATGCTTTTGTTACTCCCTCTCAATAGCGGATTTAACTATCTCTTGATTTACGGTG
CCTTTGGTGTTCCAGAACTGGGAGGGGCTGGTGCTGGTTTAGGAACATCCTTGGCCTACTGGGTCTTGCTTGGGATTTC
TGTTCTGGTTTTATTTAAACAGGAGAAGCTCAAAGCCTTACACCTTGAGAAACGAATTCCACTTAATATGGATAAAATT
AAGGAAGGAGTTCGTTTAGGTCTGCCTATTGGGGGAACTGTCTTCGCGGAAGTGGCTATCTTTTCAGTGGTTGGCTTGA
TTATGGCTAAGTTTTCGCCCTTGATTATAGCTAGTCACCAGTCAGCTATGAACTTTTCAAGTCTTATGTACGCCTTTCC
TATGAGTATCTCATCGGCTATGGCTATGTCGTTTCCTATGAAGTGGGAGCCAAGCGATTTGATGATGCGAAAACCTATA
TTGGTCTAGGAAGATGGACTGCCCTCATTTTTGCGGCCTTCACCTTAACCTTCCTTTACATTTTTAGGGGAAATGTGGC
CAGTCTTTATGGTAACGACCCAAAATTTATCGATTTGACAGTGCGTTTTTTAACTTATAGTCTTTTCTTCCAGTTAGCA
GATACCTTTGCGGCGCCGCTTCAGGGAATTTTGCGGGGGTATAAGGATACAGTTATTCCTTTTTACCTTGGTTTGCTTG
GTTATTGGGGCGTAGCAATCCCTGTGTACGCTATTTGA
4112.2
ATGAGTACTTTAGCAAAAATAGAAGCGCTCTTGTTTGTAGCGGGTGAAGATGGGATTCGGGTCCGCCGCCAAGTTAGCT
GAACTCCTCTCTCTGCCACCGACAGGCATCCAGCAAAGTTTAGGAAAATTAGCCCAGAAGTATGAAAAGGACCCAGATT
CCAGTTTGGCTTTGATTGAGACAAGTGGTGCTTATAGATTGGTGACCAAGCCTCAATTTGCAGAGATTTTGAAGGAATA
CTCTAAGGCGCCTATCAACCAGAGCTTGTCTCGGGCTGCCCTTGAGACCTTGTCCATTATTGCCTACAAACAGCCGATT
ACGCGGATAGAAATTGATGCCATCCGTGGAGTTAACTCGAGTGGAGCCTTGGCAAAGTTGCAGGCTTTTGACCTGATAA
AGGAAGACGGGAAAAAGGAAGTATTGGGGCGCCCCAACCTCTATGTGACTACGGATTATTTCCTAGATTACATGGGGAT
AAACCATTTAGAAGAATTACCAGTGATTGATGAGCTTGAGATTCAAGCCCAAGAAAGCCAATTATTTGGTGAAAGGATA
GAAGAAGATGAGAATCAATAA
4113.1
ATGGATACGATGATTAGTAGATTTTTTCGCCATTTATTTGAAGCCTTAAAAAGTTTGAAACGAAATGGTTGGATGACAG
TAGCTGCTGTCAGTTCAGTCATGATTACTTTGACCTTGGTGGCAATATTTGCATCTGTTATTTTCAATACAGCGAAACT
AGCTACAGATATTGAAAATAATGTCCGTGTAGTAGTTTATATCCGAAAGGATGTGGAAGATAATAGTCAGACAATTGAA
AAAGAAGGTCAAACTGTTACAAATAATGACTACCACAAGGTATATGATTCTTTGAAGAACATGTCTACGGTTAAAAGTG
TTACCTTTTCAAGTAAAGAAGAACAATATGAAAAATTAACCGAGATAATGGGAGATAACTGGAAAATCTTTGAAGGAGA
TGCCAATCCTCTCTATGATGCCTATATTGTAGAGGCAAACACTCCAAATGATGTAAAAACTATAGCCGAAGATGCTAAA
AAAATTGAAGGTGTCTCTGAGGTTCAAGATGGCGGTGCCAATACAGAAAGACTCTTCAAGTTAGCTTCATTTATCCGTG
TTTGGGGACTAGGGATTGCTGCTTTGTTAATTTTATCGCAGTTTTCTTGATTTCAAATACCATTCGTATTACCATTATT
TCCCGCAGTCGCGAAATTCAAATCATGCGCTTGGTCGGAGCTAAAAACAGTTATATCCGTGGACCGTTCTTGTTAGAAG
GAGCCTTTATCGGTTTATTGGGAGCTATCGCACCATCTGTTTTTGGTCTTTTATTGTTTATCAAATTGTTTACCAATCT
GTCAACAAATCGTTGGTAGGGCAAAATCTATCCATGATTAGTCCAGATTTATTTAGTCCGTTGATGATTGCCCTACTAT
TTGTGATTGGGGTTTTCATTGGTTCATTGGGATCAGGAATATCCATGCGCCGATTCTTGAAGATTTAG
4117.1
ATGAAGAAAGTAAGATTTATTTTTTTAGCTCTGCTATTTTTCTTAGCTAGTCCAGAGGGTGCAATGGCTAGTGATGGTA
CTTGGCAAGGAAAACAGTATCTGAAAGAAGATGGCAGTCAAGCAGCAAATGAGTGGGTTTTTGATACTCATTATCAATC
TTGGTTCTATATAAAAGCAGATGCTAACTATGCTGAAAATGAATGGCTAAAGCAAGGTGACGACTATTTTTACCTCAAA
TCTGGTGGCTATATGGCCAAATCAGAATGGGTAGAAGACAAGGGAGCCTTTTATTATCTTGACCAAGATGGAAAGATGA
AAAGAAATGCTTGGGTAGGAACTTCCTATGTTGGTGCAACAGGTGCCAAAGTAATAGAAGACTGGGTCTATGATTCTCA
ATACGATGCTTGGTTTTATATCAAAGCAGATGGACAGCACGCAGAGAAAGAATGGCTCCAAATTAAAGGGAAGGACTAT
TATTTCAAATCCGGTGGTTATCTACTGACAAGTCAGTGGATTAATCAAGCTTATGTGAATGCTAGTGGTGCCAAAGTAC
AGCAAGGTTGGCTTTTTGACAAACAATACCAATCTTGGTTTTACATCAAAGAAAATGGAAACTATGCTGATAAAGAATG
GATTTTCGAGAATGGTCACTATTATTATCTAAAATCCGGTGGCTACATGGCAGCCAATGAATGGATTTGGGATAAGGAA
TCTTGGTTTTATCTCAAATTTGATGGGAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCTTGGTACT
ACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTTGGTTTTATCTCAAATCTGATGG
GAAAATAGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCTTGGTACTACTTCAAATCCGGTGGTTACATGACA
GCCAATGAATGGATTTGGGATAAGGAATCTTGGTTTTACCTCAAATCTGATGGGAAAATAGCTGAAAAAGAATGGGTCT
ACGATTCTCATAGTCAAGCTTGGTACTACTTCAAATCTGGTGGCTACATGGCGAAAAATGAGACAGTAGATGGTTATCA
GCTTGGAAGCGATGGTAAATGGCTTGGAGGAAAAACTACAAATGAAAATGCTGCTTACTATCAAGTAGTGCCTGTTACA
GCCAATGTTTATGATTCAGATGGTGAAAAGCTTTCCTATATATCGCAAGGTAGTGTCGTATGGCTAGATAAGGATAGAA
AAAGTGATGACAAGCGCTTGGCTATTACTATTTCTGGTTTGTCAGGCTATATGAAAACAGAAGATTTACAAGCGCTAGA
TGCTAGTAAGGACTTTATCCCTTATTATGAGAGTGATGGCCACCGTTTTTATCACTATGTGGCTCAGAATGCTAGTATC
CCAGTAGCTTCTCATCTTTCTGATATGGAAGTAGGCAAGAAATATTATTCGGCAGATGGCCTGCATTTTGATGGTTTTA
AGCTTGAGAATCCCTTCCTTTTCAAAGATTTAACAGAGGCTACAAACTACAGTGCTGAAGAATTGGATAAGGTATTTAG
TTTGCTAAACATTAACAATAGCCTTTTGGAGAACAAGGGCGCTACTTTTAAGGAAGCCGAAGAACATTACCATATCAAT
GCTCTTTATCTCCTTGCCCATAGTGCCCTAGAAAGTAACTGGGGAAGAAGTAAAATTGCCAAAGATAAGAATAATTTCT
TTGGCATTACAGCCTATGATACGACCCCTTACCTTTCTGCTAAGACATTTGATGATGTGGATAAGGGAATTTTAGGTGC
AACCAAGTGGATTAAGGAAAATTATATCGATAGGGGAAGAACTTTCCTTGGAAACAAGGCTTCTGGTATGAATGTGGAA
TATGCTTCAGACCCTTATTGGGGCGAAAAAATTGCTAGTGTGATGATGAAAATCAATGAGAAGCTAGGTGGCAAAGATT
AG
4119.2
ATGAAAAAAGTATTACAAAAATATTGGGCATGGGCTTTTGTGGTCATCCCCCTCTTGTTACAAGCAATTTTCTTCTATG
TGCCGATGTTTCAAGGAGCCTTTTACAGTTTTACCAACTGGACAGGATTGACTTATAACTACAAATTTGTTGGCTTAAA
CAACTTTAAGCTCCTCTTCATGGATCCAAAATTCATGAATGCGATTGGCTTTACCGCAATCATTGCGATTGCCATGGTG
GTTGGTGAGATTGCACTCGGGATCTTCATTGCGCGTGTCTTGAATTCTAAAATCAAAGGCCAAACCTTCTTCCGTGCTT
GGTTCTTCTTCCCAGCTGTTTTATCTGGTTTGACAGTGGCTTTGATCTTCAAGCAAGTCTTCAACTACGGTCTTCCAGC
GATTGGAAATGCCCTTCATATTGAATTTTTCCAAACCAGTCTTTTAGGGACTAAGTGGGGAGCAATCTTTGCGGCTGTC
TTTGTCCTTCTTTGGCAAGGGGTGGCTATGCCCATCATCATCTTCCTAGCTGGTTTGCAATCTATTCCAACTGAGATTA
CAGAGGCAGCAAGGATTGATGGTGCGACTAGCAAGCAAGTTTTCTGGAACATTGAATTGCCTTACTTGCTACCAAGTGT
CTCTATGGTCTTTATCCTAGCCCTAAAAGGTGGGCTGACTGCCTTTGACCAAGTCTTTGCCATGACCGGTGGTGGTCCA
AACAATGCCACAACCTCACTTGGGCTCTTGGTTTATAACTATGCCTTTAAAAACAACCAATTCGGTATGCCAATGCCAT
TGCCGTAATCTTGTTCTTCTTAATTGTAGTGATTTCGATCATCCAATTGAGAGTATCTAAGAAATTTGAAATTTTAA
4119.3
ATGATGAAACAAGATGAAAGAAAAGCCCTGATTGGCAAATACATTCTATTGATTCTAGGATCGGTTCTGATTTTAGTGC
CGCTCCTTGCTACCCTCTTTAGTTCCTTCAAACCCACTAAGGATATTGTAGATAATTTCTTTGGCTTTCCAACCAACTT
CACATGGGACAACTTTAGCCGTCTCTTAGCTGATGGGATTGGAGGCTATTATTGGAACTCTGTCGTCATCACTGTCTTG
TCTTTACTTGCAGTAATGATCTTTATCCCTATGGCAGCGTACTCCATCGCTCGCAATATGAGTAAAAGAAAAGCCTTTA
CCATCATGTATACCCTCTTAATCCTCGGAATCTTCGTACCTTTCCAAGTCATCATGATTCCGATTACGGTTATGATGAG
TAAACTCGGTTTGGCTAATACCTTTGGTTTGATCTTGCTCTACTTGACCTATGCGATTCCACAGACCCTCTTTCTCTAT
GTTGGCTATATCAAAATCTCGATTCCAGAAAGTCTGGATGAAGCAGCAGAGATCGATGGGGCTAATCAATTTACAACCT
ATTTCCGCATCATCTTCCCAATGATGAAACCGATGCATGCGACAACCATGATCATCAATGCCCTTTGGTTCTGGAATGA
CTTCATGTTGCCACTCCTTGTCTTGAACCGGGATTCCAAAATGTGGACTCTGCCTTTGTTCCAATACAACTACGCAGGC
CAATATTTCAACGACTACGGACCAAGCTTTGCCTCTTACGTGGTCGGCATTATCAGTATCACCATTGTCTATCTCTCTT
CCAACGCCATATCATTTCAGGAATGAGCAACGGGGCAGTGAAGTAA
4119.4
ATGAAAAGTATTCTTCAGAAAATGGGGGAGCATCCGATGCTGCTTCTTTTTCTTAGCTATAGTACTGTTATATCCATTC
TTGCACAAAATTGGATGGGTCTTGTGGCTTCAGTAGGAATGTTTCTATTTACTATTTTCTTTTTGCACTATCAGTCGAT
TTTATCCCATAAATTCTTTCGATTGATTTTGCAGTTTGTCTTGTTTGGTAGTGTCTTGTCAGCTGCTTTTGCCAGTTTA
GAACATTTCCAAATTGTGAAGAAATTTAACTATGCTTTTCTTTCACCCAATATGCAGGTGTGGCATCAGAACCGGGCAG
AAGTGACCTTCTTTAATCCTAATTATTATGGAATTATTTGTTGTTTCTGTATTATGATTGCTTTCTATCTGTTTACAAC
GACCAAGTTGAATTGGTTGAAAGTATTCTGTGTGATTGCAGGCTTTGTTAATCTCTTTGGTTTGAACTTTACTCAAAAT
CGAACTGCCTTTCCTGCTATTATCGCTGGAGCAATTATCTATCTCTTTACGACTATTAAAAACTCGAAGGCCTTTTGGC
TTAGTATTGGGGTCTTCGCGATTGGTTTGAGTTTCCTCTTTTCTAGTGATTTGGGAGTTCGAATGGGTACTTTAGACTC
TTCTATGGAAGAACGCATTTCTATCTGGGATGCTGGGATGGCCTTGTTTAAGCAAAATCCTTTTTGGGGTGAAGGGCCA
TTGACCTATATGAACTCTTATCCTCGGATACATGCTCCTTATCATGAACATGCCCACAGTCTTTATATTGATACGATTC
TGAGTTACGGAATTGTGGGGACTATTTTATTAGTTTTGTCTTCTGTTCGTCCTGTTCGCTTGATGATGGATATGAGTCA
GGAGTCGGGGAAACGTCCGATTATCGGCCTTTATCTATCTTTCCTTACAGTGGTTGCTGTGCACGGAATTTTTGACTTG
GCTCTCTTCTGGATTCAGTCAGGCTTTATTTTCTTGCTAGTTATGTGCAGTATTCCATTGGAGCATCGAATGTTGGTAT
CGGACATGACGGATTAA
4120.1
ATGTCAAAGATGATGTTCAGAAAATCATTGCACCGATGATGAAGTTTGTGAATATGCGTGGCATTATAGCTCTAAAAGA
TGGGATGTTAGCAATTTTGCCATTGACAGTAGTTGGTAGTTTGTTCTTGATTATGGGACAATTGCCGTTCGAAGGATTA
AATAAGAGCATTGCTAGTGTTTTTGGAGCTAATTGGACAGAGCCGTTTATGCAAGTATATTCAGGAACTTTTGCTATTA
TGGGTCTAATTTCTTGTTTTTCAATTGCCTATTCTTATGCTAAGAATAGCGGAGTAGAGGCTTTACCAGCTGGAGTTCT
ATCTGTATCTGCATTCTTTATTTTGCTAAGATCATCTTATATCCCTAAACAAGGTGAGGCGATTGGGGACGCTATTAGT
AAAGTTTGGTTTGGAGGCCAAGGAATTATCGGTGCTATCATTATAGGTTTGGTAGTAGGAAGTATTTATACCTTCTTTA
TAAAGAGAAAAATTGTTATTAAGATGCCAGAACAAGTTCCACAAGCTATTGCCAAACAGTTTGAAGCAATGATTCCAGC
ATTTGTAATTTTCTTATCTTCTATGATTGTATATATTTTAGCGAAGTCATTGACTAATGGCGGAACATTCATAGAAATG
ATTTATTCTGCTATTCAAGTTCCGTTGCAAGGTTTAACTGGATCTTTGTATGGTGCTATTGGAATTGCATTCTTTATAT
CATTTTTGTGGTGGTTTGGTGTTCATGGGCAATCGGTAGTAAATGGAGTAGTGACAGCTCTGCTTTTATCTAATCTTGA
TGCTAATAAAGCTATGTTAGCCTCTGCTAATCTATCATTAGAAAATGGTGCACATATTGTTACTCAACAATTTTTAGAT
TCATTTTTAATTCTATCAGGTTCAGGGATTACGTTTGGTCTTGTAGTTGCCATGCTTTTTGCAGCAAAATCAAAACAAT
ACCAAGCCTTAGGAAAAGTTGCAGCTTTTCCAGCAATATTTAACGTAAATGAGCCAGTTGTATTTGGATTTCCGATTGT
CATGAATCCAGTATGTTTGTACCTTTCATTCTTGTTCCTGTACTTGCAGCTGTGATAGTATATGGAGCTATTGCAACAG
GTTTCATGCAGCCATTCTCAGGGGTAACATTGCCTTGGAGTACACCAGCTATTTTATCAGGATTTTTGGTGGGTGGATG
GCAAGGAGTTATTACTCAGCTGGTGATATTAGCGATGTCTACATTGGTTTATTTTCCATTCTTTAAAGTACAGGATCGT
TTAGCTTACCAAAATGAAATCAAACAATCTTAG
4121.2
ATGAAGAAAAAGGACTTAGTAGACCAACTAGTCTCAGAGATCGAGACGGGGAAAGTCAGGACACTGGGAATATACGGTC
ATGGAGCTTCAGGTAAATCAACCTTTGCACAGGAATTGTACCAAGCTTTAGATTCTACTACAGTAAATTTGCTAGAGAC
AGATCCTTATATCACCTCAGGACGCCATCTGGTAGTACCCAAGGACGCGCCGAATCAAAAGGTGACAGCCAGTCTGCCA
GTGGCGCATGAACTGGAGAGTTTGCAGAGAGATATCCTTgCTTGCAGGCGGGTATGGATCTCTTGA
4122.1
ATGAAGAAAAGATACCTAGTCTTGACAGCTTTGCTAGCCTTGAGTCTAGCAGCTTGTTCACAAGAAAAAACAAAAAATGA
AGATGGAGAAACTAAGACAGAACAGACAGCCAAAGCTGATGGAACAGTCGGTAGTAAGTCTCAAGGAGCTGCCCAGAAGA
AAGCAGAAGTGGTCAATAAAGGTGATTACTACAGCATTCAAGGGAAATACGATGAAATCATCGTAGCCAACAAACACTA
TCCATTGTCTAAAGACTATAATCCAGGGGAAAATCCAACAGCCAAGGCAGAGTTGGTCAAACTCATCAAAGCGATGCAA
GAGGCAGGTCCCTATTAGTGATCATTACAGTGGTTTTAGAAGTTATGAAACTCAGACCAAGCTCATCAAGATTATGTCA
ACCAAGATGGAAGGCAGCAGCTGACCGTTACTCTGCCCGTCCTGGCTATAGCGAACACCAGACAGGCTTGGCCTTTGAT
GTGATTGGGACTGATGGTGATTTGGTGACAGAAGAAAAAGCAGCCCAATGGCTCTTGGATCATGCAGCTGATTATGGCT
TTGTTGTCCGTTATCTCAAAGGCAAGGAAAAGGAAACAGGCTATATGGCTGAAGAATGGCACCTGCGTTATGTAGGAAA
AGAAGCTAAAGAAATTGCTGCAAGTGGTCTCAGTTTGGAAGAATACTATGGCTTTGAAGGCGGAGACTACGTCGATTAA
4125.6
ATGCGTAAATTCTTAATTATTTTGTTGCTACCAAGTTTTTTGACCATTTCAAAAGTCGTTAGCACAGAAAAAGAAGTCG
TCTATACTTCGAAAGAAATTTATTACCTTTCACAATCTGACTTTGGTATTTATTTTAGAGAAAAATTAAGTTCTCCCAT
GGTTTATGGAGAGGTTCCTGTTTATGCGAATGAAGATTTAGTAGTGGAATCTGGGAAATTGACTCCCAAAACAAGTTTT
CAAATAACCGAGTGGCGCTTAAATAAACAAGGAATTCCAGTATTTAAGCTATCAAATCATCAATTTATAGCTGCGGACA
AACGATTTTTATATGATCAATCAGAGGTAACTCCAACAATAAAAAAAGTATGGTTAGAATCTGACTTTAAACTGTACAA
TAGTCCTTATGATTTAAAAGAAGTGAAATCATCCTTATCAGCTTATTCGCAAGTATCAATCGACAAGACCATGTTTGTA
GAAGGAAGAGAATTTCTACATATTGATCAGGCTGGATGGGTAGCTAAAGAATCAACTTCTGAAGAAGATAATCGGATGA
GTAAAGTTCAAGAAATGTTATCTGAAAAATATCAGAAAGATTCTTTCTCTATTTATGTTAAGCAACTGACTACTGGAAA
AGAAGCTGGTATCAATCAAGATGAAAAGATGTATGCAGCCAGCGTTTTGAAACTCTCTTATCTCTATTATACGCAAGAA
AAAATAAATGAGGGTCTTTATCAGTTAGATACGACTGTAAAATACGTATCTGCAGTCAATGATTTTCCAGGTTCTTATA
AACCAGAGGGAAGTGGTAGTCTTCCTAAAAAAGAAGATAATAAAGAATATTCTTTAAAGGATTTAATTACGAAAGTATC
AAAAGAATCTGATAATGTAGCTCATAATCTATTGGGATATTACATTTCAAACCAATCTGATGCCACATTCAAATCCAAG
ATGTCTGCCATTATGGGAGATGATTGGGATCCAAAAGAAAAATTGATTTCTTCTAAGATGGCCGGGAAGTTTATGGAAG
CTATTTATAATCAAAATGGATTTGTGCTAGAGTCTTTGACTAAAACAGATTTTGATAGTCAGCGAATTGCCAAAGGTGT
TTCTGTTAAAGTAGCTCATAAAATTGGAGATGCGGATGAATTTAAGCATGATACGGGTGTTGTCTATGCAGATTCTCCA
TTTATTCTTTCTATTTTCACTAAGAATTCTGATTATGATACGATTTCTAAGATAGCCAAGGATGTTTATGAGGTTCTAA
AATGA
4125.7
ATGAAAAAACAAAATAATGGTTTAATTAAAAATCCTTTTCTATGGTTATTATTTATCTTTTTCCTTGTGACAGGATTCC
AGTATTTTATTCTGGGAATAACTCAGGAGGAAGTCAGCAAATCAACTATACTGAGTTGGTACAAGAAATTACCGATGGT
AATGTAAAAGAATTAACTTACCAACCAAATGGTAGTGTTATCGAAGTTTCTGGTGTCTATAAAAATCCTAAAACAAGTA
AAGAAGAAACAGGTATTCAGTTTTTCACGCCATCTGTTACTAAGGTAGAGAAATTTACCAGCACTATTCTTCCTGCAGA
TACTACCGTATCAGAATTGCAAAAACTTGCTACTGACCATAAAGCAGAAGTAACTGTTAAGCATGAAAGTTCAAGTGGT
ATATGGATTAATCTACTCGTATCCATTGTGCCATTTGGAATTCTATTCTTCTTCCTATTCTCTATGATGGGAAATATGG
GAGGAGGCAATGGCCGTAATCCAATGAGTTTTGGACGTAGTAAGGCTAAAGCAGCAAATAAAGAAGATATTAAAGTAAG
ATTTTCAGATGTTGCTGGAGCTGAGGAAGAAAAACAAGAACTAGTTGAAGTTGTTGAGTTCTTAAAAGATCCAAAACGA
TTCACAAAACTTGGAGCCCGTATTCCAGCAGGTGTTCTTTTGGAGGGACCTCCGGGGACAGGTAAAACTTTGCTTGCTA
AGGCAGTCGCTGGAGAAGCAGGTGTTCCATTCTTTAGTATCTCAGGTTCTGACTTTGTAGAAATGTTTGTCGGAGTTGG
AGCTAGTCGTGTTCGCTCTCTTTTTGAGGATGCCAAAAAAGCAGCACCAGCTATCATCTTTATCGATGAAATTGATGCT
GTTGGACGTCAACGTGGAGTCGGTCTCGGCGGAGGTAATGACGAACGTGAACAAACCTTGAACCAACTTTTGATTGAGA
TGGATGGTTTTGAGGGAAATGAAGGGATTATCGTCATCGCTGCGACAAACCGTTCAGATGTACTTGACCCTGCCCTTTT
GCGTCCAGGACGTTTTGATAGAAAAGTATTGGTTGGTCGTCCTGATGTTAAAGGTCGTGAAGCAATCTTGAAAGTTCAC
GCTAAGAATAAGCCTTTAGCAGAAGATGTTGATTTGAAATTAGTGGCTCAACAAACTCCAGGCTTTGTTGGTGCTGATT
TAGAGAATGTCTTGAATGAAGCAGCTTTAGTTGCTGCTCGTCGCAATAAATCGATAATTGATGCTTCAGATATTGATGA
AGCAGAAGATAGAGTTATTGCTGGACCTTCTAAGAAAGATAAGACAGTTTCACAAAAAGAACGAGAATTGGTTGCTTAC
CATGAGGCAGGACATACCATTGTTGGTCTAGTCTTGTCGAATGCTCGCGTTGTCCATAAGGTTACAATTGTACCACGCG
GCCGTGCAGGCGGATACATGATTGCACTTCCTAAAGAGGATCAAATGCTTCTATCTAAAGAAGATATGAAAGAGCAATT
GGCTGGCTTAATGGGTGGACGTGTAGCTGAAGAAATTATCTTTAATGTCCAAACCACAGGAGCTTCAAACGACTTTGAA
CAAGCGACACAAATGGCACGTGCAATGGTTACAGAGTACGGTATGAGTGAAAAACTTGGCCCAGTACAATATGAAGGAA
ACCATGCTATGCTTGGTGCACAGAGTCCTCAAAAATCAATTTCAGAACAAACAGCTTATGAAATTGATGAAGAGGTTCG
TTCATTATTAAATGAGGCACGAAATAAAGCTGCTGAAATTATTCAGTCAAATCGTGAAACTCACAAGTTAATTGCAGAA
GCATTATTGAAATACGAAACATTGGATAGTACACAAATTAAAGCTCTTTAGCAAACAGGAAAGATGCCTGAAGCAGTAG
AAGAGGAATCTCATGCACTATCCTATGATGAAGTAAAGTCAAAAATGAATGACGAAAAATAA
4125.10
ATGAGGGAACCAGATTTTTTAAATCATTTTCTCAAGAAGGGATATTTCAAAAAGCATGCTAAGGCGGTTCTAGCTCTTT
CTGGTGGATTAGATTCCATGTTTCTATTTAAGGTATTGTCTACTTATCAAAAAGAGTTAGAGATTGAATTGATTCTAGC
TCATGTGAATCATAAGCAGAGAATTGAATCAGATTGGGAAGAAAAGGAATTAAGGAAGTTGGCTGCTGAAGCAGAGCTT
CCTATTTATATCAGCAATTTTTCAGGAGAATTTTCAGAAGCGCGTGCACGAAATTTTCGTTATGATTTTTTTCAAGAGG
TCATGAAAAAGACAGGTGCGACAGCTTTAGTCACTGCCCACCATGCTGATGATCAGGTGGAAACGATTTTTATGCGCTT
GATTCGAGGAACTCGCTTGCGCTATCTATCAGGAATTAAGGAGAAGCAAGTAGTCGGAGAGATAGAAATCATTCGTCCC
TTCTTGCATTTTCAGAAAAAAGACTTTCCATCAATTTTTCACTTTGAAGATACATCAAATCAGGAGAATCATTATTTTC
GAAATCGTATTCGAAATTCTTACTTACCAGAATTGGAAAAAGAAAATCCTCGATTTAGGGATGCAATCTTAGGCATTGG
CAATGAAATTTTAGATTATGATTTGGCAATAGCTGAATTATCTAACAATATTAATGTGGAAGATTTACAGCAGTTATTT
TCTTACTCTGAGTCTACACAAAGAGTTTTACTTCAAACTTATCTGAATCGTTTTTCCAGATTTGAATCTTACAAAAGCT
CAGTTTGCTGAAGTTCAGCAGATTTTAAAATCTAAAAGCCAGTATCGTCATCCGATTAAAAATGGCTATGAATTGATAA
AAGAGTACCAACAGTTTCAGATTTGTAAAATCAGTCCGCACGCTGATGAAAAGGAAGATGAACTTGTGTTACACTATCA
AAATCAGGTAGCTTATCAAGGATATTTATTTTCTTTTGGACTTCCATTAGAAGGTGAATTAATTCAACAAATACCTGTT
TCACGTGAAACATCCATACACATTCGTCATCGAAAAACAGGAGATGTTTTGATTAAAAATGGGCATAGAAAAAAACTCA
GACGTTTATTTATTGATTGAAAATCCCTATGGAAAAGAGAAACTCTGCTCTTATTATTGAGCAATTTGGTGAAATTGTC
TCAATTTTGGGAATTGCGACCAATAATTTGAGTAAAAAAACGAAAAATGATATAATGAACACTGTACTTTATATAGAAA
AAATAGATAGGTAA
4126.1
ATGAAGCGTTCTTCTCTTTTAGTTAGAATGGTTATTTCCATCTTTCTGGTCTTTCTCATTCTCCTAGCTCTGGTTGGAA
CTTTCTACTATCAATCAAGTTCTTCAGCCATTGAGGCCACCATTGAGGGCAACAGCCAAACGACCATCAGCCAGACTAG
CCACTTTATTCAGTCTTATATCAAAAAACTAGAAACCACCTCGACTGGTTTGACCCAGCAGACGGATGTTCTGGCCTAT
GCTGAGAATCCCAGTCAAGACAAGGTCGAGGGAATCCGAGATTTGTTTTTGACCATCTTGAAGTCAGATAAGGACTTGA
AAACTGTTGTGCTGGTGACCAAATCTGGTCAGGTCATTTCTACAGATGACAGTGTGCAGATGAAAACTTCCTCTGATAT
GATGGCTGAGGATTGGTACCAAAAGGCCATTCATCAGGGAGCTATGCCTGTTTTGACTCCAGCTCGTAAATCAGATAGT
CAGTGGGTCATTTCTGTCACTCAAGAACTTGTTGATGCAAAGGGAGCCAATCTTGGTGTGCTTCGTTTGGATATTTCTT
ATGAAACTCTGGAAGCCTATCTCAATCAACTCCAGTTGGGGCAGCAGGGCTTTGCCTTTCATTATCAATGAAAACCATG
AATTTGTCTACCATCCTCAACACACAGTTTATAGTTCGTCTAGCAAAATGGAGGCTATGAAACCCTACATCGATACAGG
TCAGGGTTATACTCCTGGTCACAAATCCTACGTCAGTCAAGAGAAGATTGCAGGAACTGATTGGACGGTGCTTGGCGTG
TCATCATTGGAAAAGTTAGACCAGGTTCGGAGTCAGCTCTTGTGGACCTTGCTTGGGGCCAGTGTCACATCTCTTCTTG
TCTGTCTCTGCTTAGTGTGGTTCAGTCTTAAACGCTGGATTGCTCCTTTGAAGGATTTGAGAGAAACCATGTTGGAAAT
TGCTTCTGGTGCTCAAAATCTTCGTGCCAAGGAAGTTGGTGCCTATGAACTGAGAGAAGTAACTCGCCAATTTAATGCT
ATGTTGGATCAGATTGATCAGTTGATGGTAGCTATTCGTAGCCAGGAAGAAACGACCCGTCAGTACCAACTTCAAGCCC
TTTCGAGCCAGATTAATCCACATTTCCTCTATAACACTTTGGACACCATCATCTGGATGGCTGAATTTCATGATAGTCA
GCGAGTGGTGCAGGTGACCAAGTCCTTGGCAACCTATTTCCGCTTGGCGCTCAATCAAGGCAAGGACTTGATTTGTCTC
TCTGACGAAATCAATCATGTCCGCCAGTATCTCTTTATCCAGAAACAACGCTATGGAGATAAGCTGGAATACGAAATTA
ATGAAAATGTTGCCTTTGATAATTTAGTCTTACCCAAGCTGGTCCTACAACCCCTTGTAGAAAATGCTCTTTACCATGG
CATTAAGGAAAAGGAAGGTCAGGGCCATATTAAACTTTCTGTCCAGAAACAGGATTCGGGATTGGTCATCCGTATTGAG
GATGATGGCGTTGGCTTCCAAGATGCTGGTGATAGTAGTCAAAGTCAACTCAAACGTGGGGGAGTTGGTCTTCAAAATG
TCGATCAACGGCTCAAACTTCATTTTGGAGCCAATTACCATATGAAGATTGATTCTAGACCCCAAAAAGGGACGAAAGT
TGAAATATATATAAATAGAATAGAAACTAGCTAA
4126.7
ATGAAGCGTTCTTCTCTTTTAGTTAGAATGGTTATTTCCATCTTTCTGGTCTTTCTCATTCTCCTAGCTCTGGTTGGAA
CTTTCTACTATCAATCAAGTTCTTCAGCCATTGAGGCCACCATTGAGGGCAACAGCCAAACGACCATCAGCCAGACTAG
CCACTTTATTCAGTCTTATATCAAAAAACTAGAAAACCACCTCGACTGGTTTGACCCAGCAGACGGATGTTCTGGCCTA
TGCTGAGAATCCCAGTCAAGACAAGGTCGAGGGAATCCGAGATTTGTTTTTGACCATCTTGAAGTCAGATAAGGACTTG
AAAACTGTTGTGCTGGTGACCAAATCTGGTCAGGTCACAGATGACAGTGTGCAGATGAAAACTTCCTCTGATATGATGG
CTGAGGATTGGTACCAAAAGGCCATTCATCAGGGAGCTATGCCTGTTTTGACTCCAGCTCGTAAATCAGATAGTCAGTG
GGTCATTTCTGTCACTCAAGAACTTGTTGATGCAAAGGGAGCCAATCTTGGTGTGCTTCGTTTGGATATTTCTTATGAA
ACTCTGGAAGCCTATCTCAATCAACTCCAGTTGGGGCAGCAGGGCTTTGCCTTCATTATCAATGAAAACCATGAATTTG
TCTACCATCCTCAACACACAGTTTATAGTTCGTCTAGCAAAATGGAGGCTATGAAACCCTACATCGATACAGGTCAGGG
TTATACTCCTGGTCACAAATCCTACGTCAGTCAAGAGAAGATTGCAGGAACTGATTGGACGGTGCTTGGCGTGTCATCA
TTGGAAAAGTTAGACCAGGTTCGGAGTCAGCTCTTGTGGACCTTGCTTGGGGCCAGTGTCACATCTCTTCTTGTCTGTC
TCTGCTTAGTGTGGTTCAGTCTTAAACGCTGGATTGCTCCTTTGAAGGATTTGAGAGAAACCATGTTGGAAATTGCTTC
TGGTGCTCAAAATCTTCGTGCCAAGGAAGTTGGTGCCTATGAACTGAGAGAAGTAACTCGCCAATTTAATGCTATGTTG
GATCAGATTGATCAGTTGATGGTAGCTATTCGTAGCCAGGAAGAAACGACCCGTCAGTACCAACTTCAAAGCCCTTTCG
AGCCAGATTAATCCACATTTCCTCTATAACACTTTGGACACCATCATCTGGATGGCTGAATTTCATGATAGTCAGCGAG
TGGTGCAGGTGACCAAGTCCTTGGCAACCTATTTCCGCTTGGCGCTCAATCAAGGCAAGGACTTGATTTGTCTCTCTGA
CGAAATCAATCATGTCCGCCAGTATCTCTTTATCCAGAAACAACGCTATGGAGATAAGCTGGAATACGAAATTAATGAA
AATGTTGCCTTTGATAATTTAGTCTTACCCAAGCTGGTCCTACAACCCCTTGTAGAAAATGCTCTTTACCATGGCATTA
AGGAAAAGGAAGGTCAGGGCCATATTAAACTTTCTGTCCAGAAACAGGATTCGGGATTGGTCATCCGTATTGAGGATGA
TGGCGTTGGCTTCCAAGATGCTGGTGATAGTAGTCAAAGTCAACTCAAACGTGGGGGAGTTGGTCTTCAAAATGTCGAT
CAACGGCTCAAACTTCATTTTGGAGCCAATTACCATATGAAGATTGATTCTAGACCCCAAAAAGGGACGAAAGTTGAAA
TATATATAAATAGAATAGAAACTAGCTAA
4127.4
ATGTTTTTTAAATTATTAAGAGAAGCTCTTAAAGTCAAGCAGGTTCGATCAAAAATTTTATTTACAATTTTTATCGTTT
TGGTCTTTCGTATCGGAACTAGCATTACAGTTCCTGGTGTGAATGCCAATAGCTTGAATGCTTTAAGTGGATTATCCTT
CTTAAACATGTTGAGCTTGGTGTCGGGGAATGCCCTAAAAAACTTTTCGATTTTTGCCCTAGGAGTTAGTCCCTATATC
ACCGCTTCTATTGTTGTCCAACTCTTGCAAATGGATATTTTACCCAAGTTTGTAGAGTGGGGTAAACAAGGGGAAGTAG
GTCGAAGAAAATTGAATCAAGCTACTCGTTATATTGCTCTAGTTCTCGCTTTTGTGCAATCTATCGGGATTACAGCTGG
TTTTAATACCTGGCTGGAGCTCAATTGATTAAAACTGCTTTAACTCCACAAGTTTTTCTGACGATTGGTATCATCTTAA
CAGCTGGTAGTATGATTGTCACTTGGTTGGGTGAGCAAATTACAGATAAGGGATACGGAAACGGTGTTTCCATGATTAT
CTTTGCCGGGATTGTTTCCTCAATTCCAGAGATGATTCAGGGCATCTATGTGGACTACTTTGTGAACGTCCCAAGTAGC
CGTATCACTTCATCTATCATTTTCGTAATCATTTTGATTATTACTGTATTGTTGATTATTTACTTTACAACTTATGTTC
AACAAGCAGAATACAAAATTCCAATCCAATATACTAAGGTTGCACAAGGTGCTCCATCTAGCTCTTACCTTCCGTTAAA
AGTAAACCCTGCTGGAGTTATCCCTGTTATCTTTGCCAGTTCGATTACTGCAGCGCCTGCGGCTATTCTTCAGTTTTTG
AGTGCCACAGGTCATGATTGGGCTTGGGTAAGGGTAGCACAAGAGATGTTGGCAACTACTTCTCCAACTGGTATTGCCA
TGTATGCTTTGTTGATTATTCTCTTTACATTCTTCTATACGTTTGTACAGATTAATCCTGAAAAAGCAGCAGAGACCTA
CAAAAGAGTGGTGCCTATATCCATGGAGTTCGTCCTGGTAAAGGTACAGAAGAATATATGTCTAAACTTCTTCGTCGTC
TTGCAACTGTTGGTTCCCTCTTCCTTGGTGTGA
4127.5
ATGGATATTAGACAAGTTACTGAAACCATCGCCATGATTGAGGAGCAAAACTTCGATATTAGAACCATTACCATGGGGA
TTTCTCTTTTGGACTGTATCGATCCAGATATCAATCGTGCTGCGGAGAAATCTATCAAAAAAYTACGACAAAGGCGGCT
AATTTAGTAGTGTTGGTGATGAAATTGCGGCTGAGTTGGGAATTCCTATCGTTAATAAGCGTGTATCGGTGACACCTAT
TCTCTGATTGGGGCAGCGACAGATGCGACGGACTACGTGGTTCTGGCAAAAGCGCTTGATAAGGCTGCGAAAGAGATTG
GTGTGGACTTTATTGGTGGTTTTTCTGCCTTAGTACAAAAAGGTTATCAAAAGGGAGATGAGATTCTCATCAATTCCAT
TCCTCGCGCTTTGGCTGAGACGGATAAGGTCTGCTCGTCAGTCAATATCGGCTCAACCAAGTCTGGTATTAATATGACG
GCTGTGGCAGATATGGGACGAATTATCAAGGAAACAGCAAATCTTTCAGATATGGGAGTGGCCAAGTTGGTTGTATTCG
CTAATGCTGTTGAGGACAATCCATTTATGGCGGGTGCCTTTCATGGTGTTGGGGAAGCAGATGTTATCATCAATGTCGG
AGTTTCTGGCCTGGTGTTGTGAAACGTGCTTTGGAAAAAGTTCGTGGACAGAGCTTTGATGTAGTAGCCGAAACAGTTA
AGAAAACTGCCTTTAAAATCACTCGTATCGGTCAATTGGTTGGTCAAATGGCCAGTGAGAGACTGGGTGTGGAGTTTGG
TATTGTGGACTTGAGTTTGGCACCAACCCCTGCGGTTGGAGACTCTGTGGCACGTGTCCTTGAGGAAATGGGGCTAGAA
ACAGTTGGCACGCATGGAACGACGGCTGCCTTGGCCCTCTTGAACGACCAAGTTAAAAAGGGTGGAGTGATGGCCTGCA
ACCAAGTCGGTGGTTTATCTGGTGCCTTTATCCCTGTTTCTGAGGATGAAGGAATGATTGCTGCAGTGCAAAATGGCTC
TCTTAATTTAGAAAAACTAGAAGCTATGACGGCTATCTGTTCTGTTGGATTGGATATGATTGCCATCCCAGAAGATACG
CCTGCTGAAACTATTGCGGCTATGATTGCGGATGAAGCAGCAATCGGTGTTATCAACATGAAAACAACAGCTGTTCGTA
TCATTCCCAAAGGAAAAGAAGGCGATATGATTGAGTTTGGTGGTCTATTAGGAACTGCACCCGTTATGAAGGTTAATGG
GGCTTCGTCTGTCGACTTCATCTCTCGCGGTGGACAAATCCCAGCACCAATTCATAGTTTTAAAAATTAA
4128.1
ATGACACAGATTATTGATGGGAAAGCTTTAGCGGCCAAATTGCAGGGGCAGTTGGCTGAAAAGACTGCAAAATTAAAGG
AAGAAACAGGTCTAGTGCCTGGTTTGGTAGTGATTTTGGTTGGGGACAATCCAGCCAGCCAAGTCTACGTTCGCAACAA
GGAGAGGTCAGCCCTTGCGGCTGGTTTCCGTAGCGAAGTAGTACGGGTTCCAGAGACCATTACTCAAGAGGAATTGTTA
GACCTGATTGCTAAATACAATCAGGATCCAGCTTGGCATGGGATTTTGGTTCAGTTGCCATTACCAAAACACATTGATG
AAGAGGCGGTTCTATTGGCTATTGACCCAGAAAAGATGTGGATGGTTTCCATCCTCTAAACATGGGGCGTCTTTGGTCT
GGTCATCCAGTCATGATTCCTTCGACACCGGCAGGAATTATGGAAATGTTCCATGAATATGGGATTGACTTGGAAGGTA
AAAATGCAGTCGTCATCGGTCGATCCAATATTGTCGGAAAACCTATGGCCCAGCTTCTTTTGGCAAAGAATGCAACAGT
AACCTTGACTCACTCACGTACTCATAATCTTTCCAAGGTGGCTGCAAAAGCAGATATTCTGGTTGTTGCAATCGGTCGT
GCCAAGTTTGTGACTGCTGACTTTGTCAAACCAGGTGCGGTAGTCATTGACGTTGGGATGAACCGCGATGAAAATGGTA
AGCTCTGTGGGGATGTTGATTATGAGGCGGTTGCCCCACTTGCTAGCCACATTACGCCAGTCCCTGGAGGTGTCGGTGG
TATGACCATTACTATGCTGATGGAGCAAACCTATCAGGCAGCACTTAGGACATTGGATAGAAAATAA
4128.2
ATGTCTAAATTTAATCGTATTCATTTGGTGGTACTGGATTCTGTAGGAATCGGTGCAGCACCAGATGCTAATAACTTTG
TCAATGCAGGGGTTCCAGATGGAGCTTCTGACACACTGGGACACATTTCAAAAACAGTTGGTTTGAATGTCCCAAACAT
GGCTAAAATAGGTCTTGGAAATATTCCTCGTGAAACTCCTCTTAAGACTGTAGCAGCTGAAAGCAATCCAACTGGATAT
GCAACAAAATTAGAGGAAGTATCTCTTGGTAAGGATACTATGACTGGACACTGGGAAATCATGGGACTCAACATTACTG
AGCCTTTCGATACTTTCTGGAACGGATTCCCAGAAGAAATCCTGACAAAAATCGAAGAATTCTCAGGACGAAGGTTATT
CGTGAAGCCAACAAACCTTATTCAGGAACGGCTGTTATCTATGATTTTGGACCACGTCAGATGGAAAACTGGAGAGTTG
ATTATCTATACTTCAGCTGACCCTGTTTTGCAGATTGCTGCCCACGAAGACATTATTCCTTTGGATGAATTGTACCGTA
TCTGTGAATACGCTCGTTCGATTACCCTTGAGCGTCCTGCCCTTCTTGGTCGCATCATTGCTCGCCCTTATGTAGGTGA
ACCAGGTAACTTCACTCGTACGGCAAACCGTCGTGACTTGGCTGTATCTCCATTTTTCCCAACTGTTTTGGATAAATTG
AATGAGGCTGGTATCGATACTTATGCTGTGGGTAAAATCAACGATATCTTTAACGGTGCTGGTATCAACCATGACATGG
GTCACAACAAGTCAAATAGTCATGGAATTGATACACTATTGAAGACTATGGGACTTGCTGAGTTTGAAAAAGGATTCTC
ATTCACAAACCTAGTTCAGTTTGATGCCCTTTACGGCCATCGTCGTAATGCTCACGGTTACCGTGATTGCTTGCATGAG
TTTGATGAACGCTTACCTGAAATTATCGCAGCTATGAGAGAGAATGACCTTCTCTTGATTACTGCGGACCATGGAAATG
ACCCAACGTATGCAGGAACGGATCACACTCGGGAATATATTCCATTGTTGGCCTATAGCCCTGCCTTTAAAGGAAATGG
TCTCATTCCAGTAGGACATTTTGCAGATATTTCAGCGACTGTTGCCCGATAACTTTGGTGTGGAAACTGCTATGATTGG
GGAAAGTTTCTTAGATAAATTGGTATAA
4129.2
ATGTTTATTTCCATCAGTGCTGGAATTGTGACATTTTTACTAACTTTAGTAGAAATTCCGGCCTTTATCCAATTTTATA
GAAAGGCGCAAATTACAGGCCAGCAGATGCATGAGGATGTCAAACAGCATCAGGCAAAAGCTGGGACTCCTACAATGGG
AGGTTTGGTTTTCTTGATTACTTCTGTTTTGGTTGCTTTCTTTCTTTTTCGCCTATTTAGTAGCCAATTCAGCAATAAT
GTGGGAATGATTTTGTTCATCTTGGTCTTGTATGGCTTGGTCGGATTTTTAGATGACTTTCTCAAGGTCTTTCGTAAAA
TCAATGAGGGGCTTAATCCTAAGCAAAAATTAGCTCTTCAGCTTCTAGGTGGAGTTATCTTCTATCTTTTCTATGAGCG
CGGTGGCGATATCCTGTCTGTCTTTGGTTATCCAGTTCATTTGGGATTTTTCTATATTTTCTTCGCTCTTTTCTGGCTA
GTCGGTTTTTCAAACGCAGTAAACTTGACAGACGGTGTTGACGGTTTAGCTAGTATTTCCGTTGTGATTAGTTTGTCTG
CCTATGGAGTTATTGCCTATGTGCAAGGTCAGATGGATATTCTTCTAGTGATTCTTGCCATGATTGGTGGTTTGCTCGG
TTTCTTCATCTTTAACCATAAGCCTGCCAAGGTCTTTATGGGTGATGTGGGAAGTTTGGCCCTAGGTGGGATGCTGGCA
GCTATCTCTATGGCTCTCCACCAAGAATGGACTCTCTTGATTATCGGAATTGTGTATGTTTTTGAAACAACTTCTGTTA
TGATGCAAGTCAGTTATTTCAAACTGACAGGTGGTAAACGTATTTTCCGTATGACGCCTGTACATCACCATTTTGAGCT
TGGGGGATTGTCTGGTAAAGGAAATCCTTGGAGCGAGTGGAAGGTTGACTTCTTCTTTTGGGGAGTGGGACTTCTAGCA
AGTCTCCTGACCCTAGCAATTTTATATTTGATGTAA
4133.1
TTGTTTAAGAAAAATAAAGACATTCTTAATATTGCATTGCCAGCTATGGGTGAAAACTTTTTGCAGATGCTAATGGGAA
TGGTGGACAGTTATTTGGTTGCTCATTTAGGATTGATAGCTATTTCAGGGGTTTCAGTAGCTGGTAATATTATCACCAT
TTATCAGGCGATTTTCATCGCTCTGGGAGCTGCTATTTCCAGTGTTATTTCAAAAAGCATAGGGCAGAAAGACCAGTCG
AAGTTGGCCTATCATGTGACTGAGGCGTTGAAGATTACCTTACTATTAAGTTTCCTTTTAGGATTTTTGTCCATCTTCG
CTGGGAAAGAGATGATAGGACTTTTGGGGACGGAGAGGGATGTAGCTGAGAGTGGTGGACTGTATCTATCTTTGGTAGG
CGGATCGATTGTTCTCTTAGGTTTAATGACTAGTCTAGGAGCCTTGATTCGTGCAACGCATAATCCACGTCTGCCTCTC
TATGTTAGTTTTTTATCCAATGCCTTGAATATTCTTTTTTCAAGTCTAGCTATTTTTGTTCTGGATATGGGGATAGCTG
GTGTTGCTTGGGGGACAATTGTGTTCTCGTTTGGTTGGTCTTGTGATTTTGTGGTCACAATTAAAACTGCCTTATGGGA
AGCCAACTTTTGGTTTAGATAAGGAACTGTTGACCTTGGCTTTACCAGCAGCTGGAGAGCGACTTATGATGAGGGCTGG
AGATGTAGTGATCATTGCCTTGGTCGTTTCTTTTGGGACGGAGGCAGTTGCTGGGAATGCAATCGGAGAAGTCTTGACC
CAGTTTAACTATATGCCTGCCTTTGGCGTCGCTACGGCAACGGTCATGCTGTTGGCCCGAGCAGTTGGAGAGGATGATT
GGAAAAGAGTGCTAGTTTGAGTAAACAAACCTTTTGGCTTTCTCTGTTCCTCATGTTGCCCCTGTCCTTTAGTATATAT
GTCTTGGGTGTACCATTAACTCATCTCTATACGACTGATTCTCTAGCGGTGGAGGCTAGTGTTCTAGTGACACTGTTTT
CACTACTTGGGACCCCTATGACGACAGGAACAGTCATCTATACGGCAGTCTGGCAGGGATTAGGAAATGCACGCCTCCC
TTTTTATGCGACAAGTATAGGAATGTGGTGTATCCGCATTGGGACAGGATATCTGATGGGGATTGTGCTTGGTTGGGGC
TTGCCTGGTATTTGGGCAGGGTCTCTCTTGGATAATGGTTTTCGCTGGTTATTTCTACGCTATCGTTACCAGCGCTATA
TGAGCTTGAAAGGATAG
4135.2
ATGCAAACTCAAGAAAAACACTCGCAAGCACCCGTTCTTGGCTTGCAGCACTTACTAGCCATGTACTCAGGATCTATCC
TGGTTCCCATCATGATTGCGACAGCCCTTGGCTATTCAGCTGAGCAGTTGACCTACCTGATTTCTACAGATATCTTCAT
GTGTGGGGTGGCAACCTTCCTCCAACTCCAACTCAACAAATACTTTGGGATTGGACTCCCAGTCGTTCTTGGAGTTGCA
TTCCAGTCGGTCGCTCCCTTGATTATGATTGGGCAAAGCCATGGTAGTGGCGCTATGTTTGGTGCCCTTATCGCATCTG
GGATTTACGTGGTTCTTGTTTCAGGCATCTTCTCAAAAGTAGCCAATCTCTTCCCATCTATCGTAACAGGATCTGTTAT
TACCACGATTGGTTTAACCTTGATCCCTGTCGCTATTGGAAATATGGGAAATAACGTTCCAGAGCCAACTGGTCAAAGT
CTCTTGCTTGCAGCTATTACTGTTCTGATTATCCTCTTGATCAACATCTTTACCAAAGGATTTATCAAGTCTATCTCTA
TTTTGATTGGTCTGGTTGTTGGAACTGCCATTGCTGCTACTATGGGCTTGGTGGACTTCTCTCCTGTTGCGGTAGCTCC
ACTTGTCCATGTCCCAACTCCACTCTACTTTGGGATGCCAACCTTTGAAATCTCATCTATTGTCATGATGTGTATCATC
GCAACGGTGTCTATGGTTGAGTCAACTGGTGTTTATCTGGCCTTGTCTGATATCACAAAGGATCCAATCGACAGCACGC
GCCTTCGCAACGGATACCGCGCAGAAGGTTTGGCCGTACTTCTCGGAGGAATCTTTAACACCTTCCCTTACACCGGATT
TTCACAAAACGTTGGTTTGGTTAAATTGTCAGGCATCAAAAAACGCCTGCCAATCTACTACGCAGCTGGTTTCCTGGTT
CTCCTTGGACTGCTTCCTAAGTTTGGCGCCCTTGCCCAAATCATTCCAAGCTCCGTCCTCGGTGGTGCCATGCTGGTAA
TGTTTGGTTTTGTATCAATTCAAGGGATGCAAATCCTCGCCCGTGTTGACTTTGCTAACAATGAACACAACTTCCTTAT
CGCAGCTGTTTCAATCGCTGCAGGTGTCGGTCTCAACAACAGTAATCTCTTTGTCAGCATGCCGACAGCCTTCCAAATG
TTCTTCTCAAACGGAATCGTCGTAGCCAGCCTACTCGCTATTGTCCTCAATGCCGTATTAAATCATAAAAAGAAATAA
4136.2
ATGAAAGATAGAATAAAAGAATATTTACAAGACAAGGGAAAGGTGACTGTTAATGATTTGGCTCAGGCTTTGGGAAAGA
CAGTTCCAAGGATTTTCGTGAGTTGATTAAAACCTTGTCCTTAATGGAAAGAAAGCACCAAATTCGTTTTGAAGAAGAT
GGTAGTCTGACATTAGAAATTAAGAAAAAACATGAGATTACCCTCAAGGGGATTTTTCATGCCCATAAAAATGGCTTTG
GCTTTGTTAGTCTGGAAGGCGAGGAGGACGACCTTTTTGTAGGGAAAAATGATGTCAACTATGCTATTGATGGTGATAC
CGTCGAGGTAGTGATTAAGAAAGTCGCTGACCGCAATAAGGGAACAGCAGCAGAAGCCAAAATTATTGATATCCTAGAA
CACAGTTTGACAACAGTTGTCGGGCAAATCGTTCTGGATCAGGAAAAACCTAAGTATGCTGGCTATATTCGTTCAAAAA
ATCAGAAAATCAGTCAACCGATTTATGTTAAGAAACCAGCCCTAAAATTAGAAGGAACAGAAGTTCTCAAAGTCTTTAT
CGATAAATACCCAAGCAAGAAACATGATTTCTTTGTCGCGAGTGTTCTCGATGTAGTGGGACACTCAACGGATGTCGGA
ATTGATGTTCTTGAGGTCTTGGAATCAATGGACATTGTATCCGAGTTTCCAGAAGCTGTTGTTAAGGAAGCAGAAAGTG
TGCCTGATGCTCCGTCTCAAAAGGATATGGAAGGTCGTCTGGATCTAAGAGATGAAATTACCTTTACCATTGACGGTGC
GGATGCCAAGGACTTGGACGATGCAGTGCATATCAAGGCTCTGAAAAATGGCAATCTGGAGTTTGGGGTTCACATCGCA
GATGTTTCTTATTATGTGACCGAGGGGTCTGCCCTTGACAAGGAAGCCCTTAACCGTGCGACTTCTGTTTACGTGACAG
ACCGAGTGGTGCCAATGCTTCCAGAACGACTATCAAATGGCATCTGCTCTCTCAATCCCCAAGTTGACCGCCTGACCCA
GTCTGCTATTATGGAGATTGATAAACATGGTCGTGTGGTCAACTATACCATTACACAAACAGTTATCAAGACCAGTTTT
CGTATGACCTATAGCGATGTCAATGATATCCTAGCTGGCGATGAAGAAAAGAGAAAAGAATATCATAAAATTGTATCAA
GTATCGAACTCATGGCCAAGCTTCATGAAACTTTAGAAAACATGCGTGTGAAACGTGGAGCTCTCAATTTTGATACCAA
TGAAGCGAAGATTTTAGTGGATAAACAAGGTAAGCCTGTTGATATCGTTCTTCGGCAGCGTGGTATTGCCGAGCGGATG
ATTGAGTCTTTTATGTTGATGGCTAATGAAACAGATTGCCGAACATTTCAGCAAGTTGGATTTGCCTTTTATCTATCGA
ATTCACGAGGAGCCTAAGGCTGAAAAGGTTCAGAAGTTTATTGATTATGCTTCGAGTTTTGGCTTGCGCATTTATGGAA
CTGCCAGTGAGATTAGTCAGGAGGCACTTCAAGACATCATGCGTGCTGTTGAGGGAGAACCTTATGCAGATGTATTGTC
CATGATGCTTCTTCGCTCTATGCAGCAGGCTCGTTATTCGGAGCACAATCACGGCCACTATGGACTAGCTGCTGACTAT
TATACTCACTTTACCAGTCCAATTCGTCGTTATCCAGACCTTCTTGTTCACCGTATGATTCGGGATTACGGCCGTTCTA
AGGAAATAGCAGAGCATTTTGAACAAGTGATTCCAGAGATTGCGACCCAGTCTTCCAACCGTGAACGTCGTGCCATAGA
AGCTGAGCGTGAAGTCGAAGCCATGAAAAAGGCTGAGTATATGGAAGAATACGTGGGTGAAGAGTATGATGCAGTTGTA
TCAAGTATTGTCAAATTCGGTCTCTTTGTCGAATTGCCAAACACAGTTGAAGGCTTGATTCACATCACTAATCTGCCTG
AATTTTATCATTTCAATGAGCGTGATTTGACTCTTCGTGGAGAAAAATCAGGTATCACTTTCCGAGTGGGTCAGCAGAT
CCGTATCCGTGTTGAAAGAGCGGATAAAATGACTGGAGAGATTGATTTTTCATTCGTACCTAGTGAGTTTGATGTGATT
GAAAAAGGCTTGAAACAGTCTAGTCGTAGTGGCAGAGGGCGTGATTCAAATCGTCGTTCGGATAAGAAGGAAGACAAGA
GAAAATCAGGACGCTCAAATGATAAGCGTAAGCATTCACAAAAAGACAAGAAGAAAAAAGGAAAGAAACCTTTTTACAA
GGAAGTAGCTAAGAAAGGAGCCAAGCATGGCAAAGGGCGAGGGAAAGGTCGTCGCACAAAATAA
4137.2
ATGGGCACAACAGGATTTACAATAATTGACTTAATTATCTTGATTGTTTATTTACTTGCGGTGTTGGTTGCACGTATCT
ATTTCTCTAAAAAAGAGATGAAAGGAAAAGAGTTCTTTAAAGGAGATGGTTCGGTTCCTTGGTATGTTACTTCGGTATC
CATTTTTGCCACAATGCTCAGTCCGATTTCCTTCTTGGGACTCGCTGGTAGCTCTTATGCAGGTAGCTGGATTTTATGG
TTTTGCTCAATTAGGGATGGTAGTAGCTATTCCACTGACAATTCGTTTTATCTTACCTATCTTTGCACGGATAGACATC
GATACGGCATATGATTACTTGGATAAACGTTTTAATTCTAAAGCACTTCGTATTATTTCAGCACTCTTGTTTATTATTT
ATCAATTGGGACGTATGTCTATCATTATGTACCTCCCATCAGCTGGTTTATCAGTATTGACAGGAATTGACATCAATAT
TTTGATTATTTTGATGGGTGTAGTTGCAATTGTTTATTCTTATACTGGTGGTCTAAAATCCGTATTATGGACAGACTTT
ATTCAAGGTGTGATTCTGATTAGTGGTGTCGTTTTACCTTTATTTGTACTGATTGCTAATATTAAAGGTGGCTTTCGTG
CAGTAGCAGAAACATTAGCAAACGGGAAATTCCTTGCTGCAAATGAAAAACTTTTCGATCCTAACTGCTTTCAAACTCC
ATCTTTTTAATTGTGATGGGTTCAGGCTTTACAATCTTGTCTTCCTATGCTTCATCTCAAGATTTGGTTCAACGTTTTA
CTACAACACAAAATATTAAGAAACTTAATAAGATGTTGTTCACAAACGGTGTTTTGTCACTTGCAACTGCAACAGTCTT
TTACTTGATTGGTACAGGCTTGTACGTATTCTATCAAGTACAAAATGCAGATAGTGCAGCTAGCAATATCCCTCAAGAC
CAAATCTTTATGTACTTTATTGCATACCAGTTACCAGTAGGTATCACAGGTTTGATCTTGGCAGCGATTTATGCAGCAT
CTCAATCAACTATTTCAACAGGTTTGAACTCTGTTGCAACTTCATGGACATTGGATATTCAAGATGTCATTTCTAAAAA
TATGTCAGACAATCGTCGTACGAAAATTGCACAATTCGTATCTCTAGCAGTAGGTTTATTCTCAATTGGTGTTTCCATT
GTCATGGCTCACTCAGATATTAAATCTGCATACGAATGGTTCAATAGTTTCATGGGACTTGTACTTGGTCTACTTGGTG
GTGTATTTATTCTTGGATTTGTTTCTAAAAAAGCAAATAAACAAGGTGCTTATGCAGCGCTGATTGTATCAACCATCGT
CATGGTATTTATTAAATACTTCCTTCCTCCAACAGCGTTAGCTACTGGGCATATTCATTGATTTCAATCTCTGTATCAG
TAGTTTCAGGTTATATTGTATCTGTTCTTACTGGAAATAAAGTATCTGCACCTAAATATACAACGATTCATGATATTAC
AGAAATTAAAGCGGATTCAAGTTGGGAAGTTCGTCACTAA
4138.1
ATGAAATTTAGTAAAAAATATATAGCAGCTGGATCAGCTGTTATCGTATCCTTGAGTCTATGTGCCTATGCACTAAACC
AGCATCGTTCGCAGGAAAATAAGGACAATAATCGTGTCTCTTATGTGGATGGCAGCCAGTCAAGTCAGAAAAGTGAAAA
CTTGACACCAGACCAGGTTAGCCAGAAAGAAGGAATTCAGGCTGAGCAAATTGTAATCAAAATTACAGATCAGGGCTAT
GTAACGTCACACGGTGACCACTATCATTACTATAATGGGAAAGTTCCTTATGATGCCCTCTTTAGTGAAGAACTCTTGA
TGAAGGATCCAAACTATCAACTTAAAGACGCTGATATTGTCAATGAAGTCAAGGGTGGGTTATATCATCAAGGTCGATG
GAAAATATTATGTCTACCTGAAAGATGCAGCTCATGCTGATAATGTTCGAACTAAAGATGAAATCAATCGTCAAAACAA
GAACATGTCAAAGATAATGAGAAGGTTAACTCTAATGTTGCTGTAGCAAGGTCTCAGGGACGATATACGACAAATGATG
GTTATGTCTTTAATCCAGCTGATATTATCGAAGATACGGGTAATGCTTATATCGTTCCTCATGGAGGTCACTATCACTA
CATTCCCAAAAGCGATTTATCTGCTAGTGAATTAGCAGCAGCTAAAGCACATCTGGCTGGAAAAAATATGCAACCGAGT
CAGTTAAGCTATTCTTCAACAGCTAGTGACAATAACACGCAATCTGTAGCAAAAGGATCAACTAGCAAGCCAGCAAATA
AATCTGAAAATCTCCAGAGTCTTTTGAAGGAACTCTATGATTCACCTAGCGCCCAACGTTACAGTGAATCAGATGGCCT
GGTCTTTGACCCTGCTAAGATTATCAGTCGTACACCAAATGGAGTTGCGATTCCGCATGGCGACCATTACCACTTTATT
CCTTACAGCAAGCTTTCTGCCTTAGAAGAAAAGATTGCCAGAATGGTGCCTATCAGTGGAACTGGTTCTACAGTTTCTA
CAAATGCAAAACCTAATGAAGTAGTGTCTAGTCTAGGCAGTCTTCAAGCAATCCTTCTTCTTTAACGACAAGTAAGGAG
CTCTCTTCAGCATCTGATGGTTATATTTTTAATCCAAAAGATATCGTTGAAGAAACGGCTACAGCTTATATTGTAAGAC
ATGGTGATCATTTCCATTACATTCCAAAATCAAATCAAATTGGGCAACCGACTCTTCCAAACAATAGTCTAGCAACACC
TTCTCCATCTCTTCCAATCAATCCAGGAACTTCACATGAGAAACATGAAGAAGATGGATACGGATTTGATGCTAATCGT
ATTATCGCTGAAGATGAATCAGGTTTTGTCATGAGTCACGGAGACCACAATCATTATTTCTTCAAGAAGGACTTGACAG
AAGAGCAAATTAAGGTGCGCAAAAACATTTAG
4139.1
ATGAAAAAAAGAGCAATAGTGGCAGTCATTGTACTGCTTTTGATTGGGCTGGATCAGTTGGTCAAATCCTATATCGTCC
AGCAGATTCCACTGGGTGAAGTGCGCTCCTGGATCCCCAATTTCGTTAGCTTGACCTACCTGCAAAATCGAGGTGCAGC
CTTTTCTATCTTACAAGATCAGCAGCTGTTATTCGCTGTCATTACTCTGGTTGTCGTGATAGGTGCCATTTGGTATTTA
CATAAACACATGGAGGACTCATTCTGGATGGTCTTGGGTTTGACTCTAATAATCGCGGGTGGTCTTGGAAACTTTATTG
ACAGGGTCAGTCAGGGTTTGTTGTGGATATGTTCCACCTTGACTTTATCAACTTTGCAATTTTCAATGTGGCAGATAGC
TATCTGACGGTTGGAGTGATTATTTTATTGATTGCAATGCTAAAAGAGGAAATAAATGGAAATTAA
4139.5
ATGAATACAAATCTTGCAAGTTTTATCGTTGGACTGATCATCGATGAAAACGACCGTTTTTACTTTGTGCAAAAGGATG
GTCAAACCTATGCTCTTGCTAAGGAAGAAGGCCAACATACAGTAGGGGATACGGTCAAAGGTTTTGCATACACGGATAT
GAAGCAAAAACTCCGCCTGACAACCTTAGAAGTGACTGCCACTCAGGACCAATTTGGTTGGGGACGTGTCACAGAGGTT
CGTAAGGACTTGGGTGTCTTTGTGGATACAGGCCTTCCTGACAAGGAAATCGTTGTGTCACTCGATATTCTCCCTGAGC
TCAAGGAACTCTGGCCTAAGAAGGGCGACCAACTCTACATCCGTCTTGAAGTGGATAAGAAAGACCGTATCTGGGGCCT
CTTGGCTTATCAAGAAGACTTCCAACGTCTTGCTCGTCCTGCCTACAACAACATGCAGAACCAAAACTGGCCAGCCATT
GTTTACCGTCTCAAGCTGTCAGGAACTTTTGTTTACCTACCAGAAAATAATATGCTTGGTTTTATTCATCCTAGCGAGC
GTTACGCAGAGCCACGTTTGGGGCAAGTATTAGATGCGCGCGTTATTGGTTTCCGTGAAGTGGACCGCACTCTGAACCT
CTCCCTCAAACCACGCTCCTTTGAAATGTTGGAAAACGATGCTCAGATGATTTTGACTTATTTGGAAAGCAATGGCGGT
TTCATGACCTTAAATGACAAGTCATCTCCAGACGACATCAAGGCAACCTTTTGGCATTTCTAAAGGTCAGTTCAAGAAA
GCTTTAGGTGGTCTTATGAAGGCTGGTAAAATCAAGCAGGACCAGTTTGGGACAGAGTTGATTTAG
4139.8
ATGAAAGATGTTAGTCTATTTTTATTGAAAAAAGTTTTCAAAAGCCGCTTAAACTGGATTGTCTTAGCTTTATTTGTAT
CTGTACTCGGTGTTACCTTTTATTTAAATAGTCAGACTGCAAACTCACACAGCTTGGAGAGCAGGTTGGAAAGTCGCAT
TGCAGCCAACGAGAGGGCTATCAATGAAAATGAAGAGAAACTCTCCCAAATGTCTGATACCAGCTCGGAGGAATACCAG
TTTGCTAAAAATAATTTAGACGTGCAAAAAAATCTTTTGACGCGAAAGACAGAAATTCTGACTTTATTAAAAGAAGGGC
GCTGGAAAGAAGCCTACTATTTGCAGTGGCAAGATGAAGAGAAGAATTATGAATTTGTATCAAATGACCCGACTGCTAG
CCCTGGCTTAAAAATGGGGGTTGACCGCGAACGGAAGATTTACCAAGCCCTGTATCCCTTGAACATAAAAGCACATACT
TTGGAGTTTCCGACCCACGGGATTGATCAGATTGTCTGGATTTTAGAGGTTATCATCCCAAGTTTGTTTGTGGTTGCTA
TTATTTTTATGCTAACACAACTATTTGCAGAAAGATATCAAAATCATCTGGACACAGCTCACTTATATCCTGTTTCAAA
AGTGACATTTGCAATATCCTCTCTTGGAGTTGGAGTGGGATATGTAACTGTGCTGTTTATCGGAATCTGTGGCTTTTCT
TTTCTAGTGGGAAGTCTGATAAGTGGTTTTGGACAGTTAGATTATCCCTACCCAATTTATAGCTTAGTGAATCAAGAAG
TAACTATTGGGAAAATACAAGATGTATTATTTCCTGGCTTGCTCTTAGCTTTCTTAGCCTTTATCGTCATTGTGGAAGT
TGTGTACTTGATTGCTTACTTTTTCAAGCAAAAAATGCCTGTCCTCTTTCTTTCACTCATTGGGATTGTTGGCTTATTG
TTTGGTATCCAAACCATTCAGCCTCTTCAAAGGATTGCACATCTGATTCCCTTTACTTACTTGCGTTCAGTGGAGATTT
TATCTGGAAGATTACCTAAGCAGATTGATAATGTCGATCTAAATTGGAGCATGGGAATGGTCTTACTTCCTTGCCTGAT
TATCTTTTTGCTATTGGGAATTCTATTTATTGAAAGATGGGGAAGTTCACAGAAAAAAGAATTTTTTTAATAGATTCTAG
4141.1
ATGATGAAGTTCATATTGGATATTGTTAGTACACCAGCTATTTTAGTAGCTTTAATTGCAATCTTAGGATTAGTTCTTC
AGAAGAAGAAATTACCTGATATTATTAAAGGTGGAATTAAGACCTTTGTTGGTTTCTTAGTTGTATCTGGTGGTGCAGG
AATTGTACAAAATTCTTTAAATCCATTTGGTACCATGTTTGAGCATGCTTTTCATTTATCTGGCGTTGTGCCGAATAAT
GAAGCAATTGTAGCTGTAGCTTTAACAACATATGGCTCAGCTACTGCAATGATTATGTTTTGCAGGCATGGTGTTCAAT
ATCTTAATCGCTCGTTTTACTCGATTTAAATATATTTTTTTAACAGGGCACCACACTCTATATATGGCATGTATGATTG
CGGTCATTTTATCAGTTGCTGGCTTTACTAGCTTGCCTCTCATCTTACTAGGAGGATTAGCACTCGGTATTATTATGAG
TATTTCCCCAGCATTTGTGCAAAAATATATGGTTCAATTAACTGGAAATGACAAGGTAGCTTTAGGTCATTTCAGTTCT
TTGGGATATTGGTTGAGTGGTTTTACTGGTAGCCTTATCGGTGACAAATCAAAATCAACAGAGGACATTAAATTTCCAA
AGAGTTTAGCTTTTTTACGTGATAGTACTGTTAGTATTACTTTATCCATGGCAGTTATTTACATTATTGTAGCTATCTT
TGCAGGGTCAGAATATATAGAAAAAGAAATCAGTAGTGGTACAAGTGGTCTAGTTTATGCTTTACAATTAGCAGGTCAA
TTTGCAGCAGGGGTATTTGTTATTTTAGCAGGTGTTCGCCTTATTTTGGGCGAAATTGTTTCCAGCCTTTAAAGGTATT
TCAGAGCGTCTTGTACCTAATTCAAAACCTGCTTTGGATTGTCCGATTGTTTATACTTATGCACCCAATGCAGTTCTAA
TTGGATTTATCTCTAGTTTTGTTGGTGGTTTAGTAAGTATGGTAATTATGATTGCTTCAGGAACGGTGTTATCTTACCA
GGTGTTGTGCCTCATTTCTTCTGTGGAGCGACTGCAGGTGTCATTGGGAATGCATCTGGTGGTGTTCGTGGAGCCACTA
TTGGAGCATTTTTACAAGGTATTTTAATCAGTTTTCTTCCAGTCTTTTTAATGCCAGTTTTGGGAGGACTTGGTTTCCA
AGGATCAACTTTCTCAGATGCAGATTTTGGTCTATCAGGAATTATTTTAGGAATGTTAAATCAATTTGGCTCACAAGCA
GGCATTGTGATTGGTCTTGTTCTTATTCTAGCAGTTATGTTTGGAGTATCCTTTATTAAAAGCCATCTGCAACGGAGGA
ATAA
4142.3
ATGATTAAAACATTTCTCTCTGCCCTTTCGGTCATTCTCTTTTCTATCCCTATCATAACTTATTCTTTTTTCCCATCTT
CTAATCTTAACATTTGGCTATCTACCCAACCTATCTGGCACAGATTTATGCCTTCCCCTTAGCTACTGCAACTATGGCT
GCTATTTTAAGTTTCTTATTTTTTTTCCTATCTTTTTACAAGAAAAATAAACAAATACGGTTTTACTCTGGCATTTTGC
TCTTACTATCGCTCATATTACTATTATTCGGAACAGATAAAACCCTTTCTTCTGCATCAAAATAAGACTAAAACCTTAA
AATTAGTAACTTGGAACGTCGCTAATCAAATAGAAGCACAACATATTGAGCGAATTTTTAGCCATTTTGACGCCGATAT
GGCTATATTCCCTGAACTAGCTACCAATATCAGAGGTGAGCAAGAAAACCAGAGAATCAAACTATTGTTTCATCAAGTT
GGACTTTCTATGGCCAACTATGATATTTTCACTTCTCCACCTACCAATAGTGGAATAGCTCCTGTGACTGTGATTGTCA
AGAAAAGTTATGGTTTCTATACAGAAGCTAAAACTTTTCATACAACACGGTTCGGGACAATTGTATTACATTCGAGAAA
ACAAAATATACCAGATATCATTGCCTTGCATACTGCGCCTCCTCTGCCAGGTTTAATGGAAATCTGGAAGCAAGACTTA
AACATCATTCATAATCAATTGGCTTCAAAATATCCAAAGGCTATTATTGCAGGTGATTTTAATGCAACTATGCGTCATG
GAGCACTTGCAAAAATAAGCTCTCATAGGGACGCATTAAATGCACTGCCACCTTTTGAAAGAGGAACTTGGAATAGCCA
AAGTCCAAAACTTTTTAATGCAACAATAGATCATATTTTATTGCCTAAAAACCACTACTATGTTAAAGATTTAGACATT
GTAAGTTTTCAAAACTCTGATCATAGATGTATTTTTACAGAAATCACATTTTAA
4142.4
ATGAATCCAATCCAAAGATCTTGGGCTTATGTCAGCAGAAAGCGACTGAGAAGTTTTATTTTATTTCTGATTTTATTGG
TCTTATTGGCCGGAATTTCAGCCTGTTTGACTCTGATGAAGTCCAACAAAACAGTAGAAAGCAATCTTTATAAATCACT
CAATACATCTTTTTCTATTAAGAAGATAGAGAATGGTCAGACATTCAAGTTGTCAGACCTAGCATCTGTAAGCAAGATT
AAGGGGCTGGAAAATGTCTCTCCTGAACTTGAGACGGTCGCAAAACTAAAAGACAAGGAAGCAGTGACTGGCGAGCAGA
GCGTGGAGCGTGATGATTTATCAGCTGCAGACAATAACTTGGTTAGCTTAACGGCTCTTGAGGATTCATCCAAGGATGT
AACCTTTACCAGTTCGGCTTTCAATCTAAAAGAAGGGCGACACCTTCAAAAAGGGGATTCCAAGAAAATCCTTATCCAC
GAAGAATTGGCTAAGAAGAACGGTCTTTCGCTTCATGACAAGATTGGCTTGGATGCTGGTCAGTCTGAATCTGGAAAAG
GACAAACAGTAGAGTTTGAGATTATCGGCATCTTTTCTGGTAAAAAACAAGAGAAATTCACAGGCTTGTCTTCTGACTT
CAGTGAAAATCAAGTCTTTACAGACTATGAAAGTAGCCAAACCCTTTTGGGCAATAGTGAAGCTCAAGTCAGTGCAGCA
CGCTTCTATGTAGAAAATCCTAAGGAAATGGACGGACTCATGAAGCAGGTAGAAAACTTGGCCTTGGAAAATCAAGGCT
ACCAAGTCGAAAAGGAAAACAAGGCTTTTGAACAAATCAAAGACTCAGTTGCAACTTTCCAAACCTTCCTGACCATCTT
CCTTTATGGGATGTTGATAGCAGGAGCTGGAGCCTTAATTCTGGTTTTGTCTCTCTGGTTGAGAGAACGGGTCTATGAA
GTGGGGATTTTACTTGCACTTGGAAAAGGCAAGAGCTCGATCTTCCTACAATTCTGTTTAGAGGTAGTTTTGGTATCTC
TTGGAGCTTTGCTTCCAGCATTTGTTGCAGGAAACGCAATCACAACTTACCTACTCCAAACTCTACTAGCAAGTGGAGA
TCAGGCAAGCTTACAAGATACACTAGCCAAAGCAAGCAGTTTATCAACTAGCATCTTATCTTTTGCAGAATCCTATGTT
TTTCTAGTTCTGCTTAGTTGCTTATCTGTAGCCCTTTGTTTCCTATTCTTATTTAGAAAATCACCGAAAGAAATTTTAT
CATCTATTAGTTAA
4142.5
ATGTTACACAACGCATTTGCCTATGTTACAAGGAAGTTTTTCAAATCGATTGTCATCTTCCTATTATTCTCCTCATGGC
GAGCTTGAGTTTGGTCGGCTTGTCAATCAAGGGAGCTACTGCCAAGGCTTCTCAGGAGACCTTTAAAAATATCACCAAT
AGCTTCTCCATGCAAATCAATCGTCGCGTCAACCAAGGAACGCCTCGTGGTGCTGGGAATATCAAGGGTGAAGACATCA
AAAAAATCACCGAAAACAAGGCCATTGAGTCTTATGTCAAACGTATCAACGCTATCGGAGATTTGACTGGATATGACCT
GATTGAAACGCCAGAAACCAAGAAGAATCTCACTGCTGATCGTGCCAAGCGTTTTGGAAGTAGCTTGATGATTACAGGT
GTCAATGACTCCTCTAAAGAAGACAAGTTTGTCTCTGGTTCTTATAAACTAGTCGAAGGAGAGCACTTAACCAACGACG
ACAAGGATAAAATCCTCTTGCACAAGGACTTGGCAGCCAAACACGGCTGGAAAGTAGGGGACAAGGTTAAACTGGACTC
TAATATCTACGATGCAGATAATGAAAAAGGAGCCAAGGAAACAGTTGAAGTGACAATCAAGGGACTCTTTGATGGTCAT
AATAAGTCAGCAGTAACCTACTCACAAGAACTTTACGAAAACACAGCTATTACAGACATTCACACTGCTGCAAAACTTT
ATGGATACACAGAAGACACAGCCATTTATGGGGACGCAACCTTCTTTGTAACAGCAGACAAGAACTTGGATGATGTTAT
GAAAGAGTTGAATGGCATCAGTGGTATCAACTGGAAGAGCTACACACTCGTCAAGAGCTCCTCTAACTACCCAGCTCTT
GAGCAATCTATCTCTGGTATGTACAAGATGGCCAACCTCCTCTTCTGGGGTAGCTTGAGCTTCTCAGTTCTCCTCCTTG
CCCTCTTGCTCAGCCTTTGGATCAACGCCCGTCGCAAGGAAGTGGGAATTCTCCTCTCTATCGGCCTCAAGCAGGCAAG
TATCTTGGGTCAATTCATCACCGAATCTATCTTGATTGCTATCCCTGCTCTAGTTTCTGCTTACTTCCTAGCTAATTAC
ACTGCCCGTGCAATTGGAAACACTGTCCTTGCCAATGTGACTTCAGGTGTTGCCAAACAGGCTAGTAAGGCGGCTCAAG
CCTCTAACCTTGGTGGTGGTGCAGAAGTAGATGGCTTTAGCAAGACCTTGTCGAGCCTAGACATTTCCATTCAGACATC
AGACTTTATCATCATTTTTGTCCTTGCCTTGGTTCTAGTGGTTCTCGTTATGGCGCTTGCTTCAAGCAATCTCCTTAGA
AAACAACCAAAAGAGCTCTTGCTGGATGGTGAATAA
4144.1
ATGTCACAGGATAAACAAATGAAAGCTGTTTCTCCCCTTCTGCAGCGAGTTATCAATATCTCATCGATTGTCGGTGGGG
TTGGGAGTTTGATTTTCTGTATTTGGGCTTATCAGGCTGGGATTTTACAATCCAAGGAAACCCTCTCTGCCTTTATCCA
GCAGGCAGGCATCTGGGGTCCACCTCTCTTTATCTTTTTACAGATTTTACAGACTGTCGTCCCTATCATTCCAGGGGCC
TTGACCTCGGTGGCTGGGGTCTTTATCTACGGGCACATCATCGGGACTATCTACAACTATATCGGCATCGTGATTGGCT
GTGCCATTATCTTTTATCTAGTGCGCCTATACGGAGCTGCCTTTGTCCAGTCTGTCGTCAGCAAGCGCACCTACGACAA
GTACATCGACTGGCTAGATAAGGGCAATCGTTTTGACCGCTTCTTTATTTTTATGATGATTTGGCCCATTAGCCCAGCT
GACTTTCTCTGTATGCTGGCTGCCCTGACCAAGATGAGCTTCAAGCGCTACATGACCATCATCATTCTGACCAAACCCT
TTACCCTCGTGGTTTATACCTACGGTCTGACCTATATTATTGACTTTTTCTGGCAAATGCTTTGA
4144.2
ATGAGAAATATGTGGGTTGTAATCAAGGAAACCTATCTTCGACATGTCGAGTCATGGAGTTTCTTCTTTATGGTGATTT
CGCCGTTCCTCTTTTTAGGAATCTCTGTAGGAATTGGGCATCTCCAAGGTTCTTCTATGGCTAAAAATAATAAAGTGGC
AGTAGTGACAACAGTGCCATCTGTAGCAGAAGGACTGAAGAATGTAAATGGTGTTAACTTCGACTATAAAGACGAAGCA
AGTGCCAAAGAAGCAATTAAAGAAGAAAAATTAAAAGGTTATTTGACCATTGATCAAGAAGATAGTGTTCTAAAGGCAG
TATCATGGCGAACATCGCTTGAAAATGGAATTAAATTTGAGGTTACAGGTACACTCAATGAACTGCAAATCAGCTAATC
GTTCAACTGCTTCCTTGTCTCAAGAGCAGGAAAAACGCTTAGCGCAGACAATTCAATTCACAGAAAAGATTGATGAAGC
CAAGGAAAATAAAAAGTTTATTCAAACAATTGCAGCAGGTGCCTTAGGATTCTTTCTTTATATGATTCTGATTACCTAT
GCGGGTGTAACAGCTCAGGAAGTTGCCAGTGAAAAAGGCACCAAAATTATGGAAGTCGTTTTTTCTAGCATAAGGGCAA
GTCACTATTTCTATGCGCGGATGATGGCTCTGTTTCTAGTGATTTTAACGCATATTGGGATCTATGTTGTAGGTGGTCT
GGCTGCCGTTTTGCTCTTTAAAGATTTGCCATTCTTGGCTCAGTCTGGTATTTTGGATCACTTGGGAGATGCTATCTCA
CTGAATACCTTGCTCTTTATTTTGATCAGTCTTTTCATGTACGTAGTCTTGGCAGCCTTCCTAGGATCTATGGTTTCTC
GTCCTGAGGACTCAGGGAAAGCCTTGTCGCCTTTGATGATTTTGATTATGGGTGGTTTTTTTGGAGTGACAGCTCTAGG
TGCAGCTGGTGACAATCTCCTCTTGAAGATTGGTTCTTATATTCCCTTTATTTCGACCTTCTTTATGCCGTTTCGAACG
ATTAATGACTATGCGGGGGGGAGCAGAAGCATGGATTTCACTTGCTATTACAGTGATTTTTGCGGTGGTAGCAACAGGA
TTTATCGGACGCATGTATGCTAGTCTCGTTCTTCAAACGGATGATTTAGGGATTTGGAAAACCTTTAAACGTGCCTTAT
CTTATAAATAG
4144.3
ATGACAGAAACCATTAAATTGATGAAGGCTCATACTTCAGTGCGCAGGTTTTAAAGAGCAAGAAATTCCCCAAGTAGAC
TTAAATGAGATTTTGACAGCAGCCCAGATGGCATCATCTTGGAAGAATTTCCAATCCTACTCTGTGATTGTGGTACGAA
GTCAAGAGAAGAAAGATGCCTGTATGAATTGGTACCTCAAGAAGCCATTCGCCAGTCTGCTGTTTTCCTTCTCTTTGTC
CGGAGATTTGAACCGAGCAGAAAAGGGAGCCCGACTCATACCGACACCTTCCAACCCCAAGGTGTGGAAGGTCTCTTGA
TTAGTTCGGTCGATGCAGCTCTTGCTGGACAAAACGCCTTGTTGGCAGCTGAAAGCTTGGGCTATGGTGGTGTGATTAT
CGGTTTGGTTCGATACAAGTCTGAAGAAGTGGCAGAGCTCTTTAACCTACCTGACTACACCTATTCTGTCTTTGGGATG
GCACTGGGTGTGCCAAATCAACATCATGATATGAAACCGAGACTGCCACTAGAGAATGTTGTCTTTGAGGAAGAATACC
AAGAACAGTCAACTGAGGCAATCCAAGCTTATGACCGTGTTCAGGCTGACTATGCTGGGGCGCGTGCGACCACAAGCTG
GAGTCAGCGCCTAGCAGAACAGTTTGGTCAAGCTGAACCAAGCTCAACTAGAAAAAATCTTGAACAGAAGAAATTATTG
TAG
4146.1
ATGTTAAAACTATTGCTATTGTTGGAACAAATTCAAAACGTTCTACAACCGTCAATTGCTTCAATACATGCAAAAACAC
TTTACTGACAAAGCTGAAATTGAACTTGTTGAAATCAAGGCCATTCCTGTCTTCAACAAACCAGCTGACAAGCAAGTAC
CTGCTGAAATATTGGAAATTGCTGCTAAAATCGAAGAGGCAGATGGCGTTATTATCGGTACTCCTGAGTATGATCACTC
TATTCCAGCTGTTTTTGATGAGCGCTCTTGCTTGGTTGTCTTATGGTATTTACCCACTTTTGAACAAACCAATCATGAT
TACAGGTGCTTCTTACGGTACGCTTGGTTCATCTCGTGCCCAATTGCAACTTCGTCAAATCTTGAATGCTCCTGAAATC
AAGGCAAATGTTCTTCCAGATGAATTCTTGCTCTCACACTCTCTTCAAGCATTTAACCCAAGTGGCGACTTGGTTGACC
TTGATGTTATCAAGAAATTGGATGCCATCTTTGATGACTTCCGTATCTTTGTAAAAATCACAGAAAAATTACGTAATGC
ACAAGAATTACTTCGCAAAGATGCTGAAGACTTTGACTGGGAAAATTTGTAA
4146.2
ATGAATACCTATCAATTAAATAATGGAGTAGAAATTCCAGTATTGGGATTTGGAACTTTTAAGGCTAAGGATGGAGAAG
AAGCCTATCGTGCAGTGTTAGAAGCCTTGAAGGCTGGTTATCGTCATATTGATACGGCGGCGATTTATCAGAATGAAGA
AAGTGTTGGTCAAGCAATCAAAGATAGCGGAGTTCCACGTGAAGAAATGTTCGTAACTACCAAGCTTTGGAATAGTCAG
CAAACCTATGAGCAAACTCGTCAAGCTTTGGAAAAATCTATAGAAAAACTGGGCTTGGATTATTTGGATTTGTATTTGA
TTCATTGGCCGAACCCAAAACCGCTCAGAGAAAATGACGCATGGAAAACTCGCAATGCGGAAGTTTGGAGAGCGATGGA
AGACCTCTATCAAGAAGGGAAAATCCGTGCTATCGGCGTTAGCAATTTTCTTCCCCATCATTTGGATGCCTTGCTTGAA
ACTGCAACTATCGTTCCTGCGGTCAATCAAGTTCGCTTGGCGCCAGGTGTGTATCAAGATCAAGTCGTAGCTTACTGTC
GTGAAAAGGGAATTTTATTGGAAGCTTGGGGGCCTTTTGGACAAGGAGAACTGTTTGATAGCAAGCAAGTCCAAGAAAT
AGCAGCAAATCACGGAAAATCGGTTGCTCAGATAGCCTTGGCCTGGAGCTTGGCAGAAGGATTTTTACCACTTCCAAAA
TCTGTCACAACCTCTCGTATTCAAGCTAATCTTGATTGCTTTGGAATTGAACTGAGTCATGAGGAGAGAGAAACCTTAA
AAACGATTGCTGTTCAATCGGGTGCTCCACGAGTTGATGATGTGGATTTCTAG
4147.1
ATGAGGTGCAAAATGCTTGATCCAATTGCTATTCAACTAGGACCCCTAGCCATTCGTTGGTATGCCTTATGTATTGTGA
CAGGCTTGATTCTTGCGGTTTATTTGACCATGAAAGAAGCACCTAGAAAGAAGATCATACCAGACGATATTTTAGATTT
TATCTTAGTAGCCTTTCCCTTGGCTATTTTAGGAGCTCGTCTCTACTATGTTATTTTCCGATTTGATTACTATAGTCAG
AATTTAGGAGAGATTTTTGCCATTTGGAATGGTGGTTTGGCCATTTACGGTGGTTTGATAACTGGGGCTCTTGTGCTCT
ATATCTTTGCTGACCGTAAACTCATCAATACTTGGGATTTTCTAGATATTGCGGCGCCTAGCGTTATGATTGCTCAAAG
TTTGGGGCGTTGGGGTAATTTCTTTAACCAAGAAGCTTATGGTGCAACAGTGGATAATCTGGATTATCTACCTGGCTTT
ATCCGTGACCAGATGTATATTGAGGGGAGCTACCGTCAACCGACTTTCCTTTATGAGTCTCTATGGAATCTGCTTGGCT
TTGCCTTGATTCTGATTTTTAGACGGAAATGGAAGAGTCTCAGACGAGGTCATATCACGGCCTTTTACTTGATTTGGTA
TGGTTTCGGTCGTATGGTTATCGAAGGTATGCGAACAGATAGTCTCATGTTCTTCGGCTTTCGAGTGTCCCAATGGCTG
TCAGTTGTCCTTATCGGTCTCGGTATAATGATCGTTATTTATCAAAATCGAAAGAAGGCCCCTTACTATATTACAGAGG
AGGAAAACTAA
4147.2
ATGGGTAAATTATCCTCAATCCTTTTAGGAACCGTTTCAGGTGCAGCTCTTGCCTTGTTTTTAACAAGTGATAAGGGCA
AACAAGTTTGCAGTCAGGCTCAAGATTTTCTAGATGATTTGAGAGAAGATCCGGAGTATGCCAAGGAGCAAGTCTGTGA
AAAACTGACAGAAGTTAAGGAGCAGGCTACAGATTTTGTTCTGAAAACAAAAGAACAGGTTGAGTCAGGTGAAATCACT
GTGGACAGTATACTTGCTCAAACTAAATCCTATGCTTTTCAAGCGACAGAAGCATCAAAAAATCAATTAAATAATCTCA
AGGAGCAATGGCAAGAAAAAGCCGAAGCTCTTGATGACTCAGAAGAGATTGTGATTGATATAACAGAAGAATAA
4147.3
ATGAAAACTAAATTGATCTTTTGGGGCTCTATGCTCTTTCTCCTCTCCCTCTCCATCCTTCTGACCATTTATCTGGCTT
GGATTTTCTATCCTATGGAGATTCAGTGGCTAAACTTAACGAATCGAGTCTATCTAAAACCAGAAACCATTCAATACAA
TTTTCATATCTTGATGAATTATCTGACCAATCCTTTTAGTCAGGTCTTACAGATGCCTGATTTTCGTTCGTCAGCAGCT
GGTCTGCACCATTTCGCAGTGGTCAAGAATCTCTTTCATTTGGTTCAGCTAGTAGCTCTAGTGACACTGCCAAGTTTCT
ATGTCTTTGTCAATAGGATTGTGAAAAAGGACTTTTTGTCTCTTTATCGAAAAAGTCTCCTGGCTCTAGTAGTCTTACC
TGTGATGATTGGACTTGGGGGAGTTTTTGATTGGTTTTGACCAATTCTTTACTCTTTTCCATCAAATTCTCTTTGTGGG
AGATGATACCTGGCTTTTTGATCCAGCCAAGGATCCTGTTATTATGATTTTGCCAGAGACCTTCTTTCTTCATGCCTTC
CTCCTCTTTTTTGCCCTCTATGAAAACTTCTTTGGCTATCTGTATCTGAAAAGTCGTAGGAAGTGA
4149.1
ATGACTTATCATTTTACTGAAGAATACGATATTATTGTAATTGGTGCGGGACACGCTGGGGTTGAGGCTTCCTTGGCCG
CTAGCCGTATGGGCTGTAAGGTCCTGCTTGCGACCATCAATATTGAAAATGCTGGCTTTCATGCCTTGTAATCCCTCTA
TCGGTGGTTCTGCCAAGGGGATTGTCGTGCGTGAAGTCGATGCCCTCGGTGGCGAGATGGCCAAAACCATTGACAAGAC
TTACATCCAGATGAAGATGCTAAACACAGGGAAGGGGCCAGCTGTCCGTGCCCTTCGTGCGCAGGCTGACAAGGAACTT
TACTCTAAGGAGATGCGCAAGACGGTTGAAAACCAAGAAAATCTGACCCTTCGTCAAACCATGATTGATGAGATTTTGG
TGGAAGATGGCAAGGTTGTCGGTGTGCGTACAGCCACCCATCAAGAATATGCTGCTAAGGCTGTTATTGTGACGACAGG
GACTGCTCTCCGTGGGGAAATTATCATCGGAGACCTCAAGTACTCATCAGGTCCTAACCACAGCTTGGCTTCTATTAAC
CTAGCTGACAATCTCAAGGAACTGGGTCTCGAAATCGGTCGTTTCAAGACAGGAACCCCTCCACGTGTCAAGGCTTCTT
CTATCAATTACGATGTGACAGAAATTCAGCCAGGAGACGAAGTGCCTAATCATTTCTCATACACTTCACGTGATGAGGA
TTATGTCAAGGACCAAGTACCATGCTGGTTGACCTATACCAATGGTACCAGTCATGAGATTATCCAAAACAACCTCCAC
CGTGCGCCTATGTTTACAGGTGTGGTCAAGGGAGTGGGGCCTCGTTACTGTCCGTCGATTGAAGACAAGATTGTGCGTT
TGCGGACAAGGAACGTCACCAACTCTTCCTTGAGCCAGAAGGGCGCAATACTGAGGAAGTCTATGTGCAAGGACTTTCA
ACCAGTCTGCCTGAGGATGTCCAGCGTGACTTGGTGCATTCCATCAAAGGTTTGGAAAATGCAGAGATGATGCGGACAG
GTTATGCTATTGAGTATGATATGGTCTTGCCTCATCAGTTGCGTGCGACTTTGGAAACCAAGAAAATCTCAGGTCTCTT
CACTGCTGGTCAGACAAATGGAACATCAGGTACGAAGAGGCAGCAGGCCAAGGGATTATCGCGGGTATCAATGCGGCTC
TGAAAATCCAAGGCAAGCCTGAATTGATTTTGAAGCGCAGTGATGGTTATATCGGGGGTGATGATCGACGACTTGGTGA
CCAAGGGAACCATTGAACCCTACCGTCTCTTGACCAGTCGTGCTGAATACCGTCTCATTCTTCGTCATGACAATGCTGA
TATGCGCTTGACTGAGATGGGACGCGAGATTGGCCTTGTGGACGATGAACGCTGGGCTCGTTTTGAAATCAAGAAAAAT
CAATTTGATAATGAGATGAAGCGCCTAGACAGTATCAAACTCAAGCCAGTCAAGGAAACCAATGCCAAGGTTGAGGAGA
TGGGCTTCAAACCCTTGACCGATGCAGTGACAGCCAAGGAATTCCTTCGCCGTCCAGAAGTTTCTTACCAAGATGTGGT
GGCCTTCATCGGACCAGCTGCAGAAGACTTGGATGACAAGATTATCGAATTGATTGAAACAGAAATCAAGTATGAAGGC
TATATTTCCAAAGCCATGGACCAGGTTGCCAAGATGAAACGCATGGAAGAAAAACGCATTCCGGCCAATATCGACTGGG
ATGACATTGATTCTATCGCAACCGAAGCCCGTCAGAAGTTCAAACTCATCAATCCAGAAACCATCGGCCAAGCCAGCCG
TATTTCGGGAGTAAACCCAGCAGATATTTCTATTTTGATGGTGTATCTGGAAGGTAAAAATCGTAGTATTTCTAAAACT
CTTCAAAAATCAAAATGA
4149.2
ATGAAAGTATTAGCTTTTGATACGTCCAGCAAGGCTCTTTCTCTGGCTATTTTAGAGGATAAGCAGGTTCTTGCCGAGA
CGACGATTAATATTAAGAAAAATCACAGTATTACTCTTATGCCTGCCATCGATTTTTTGATGGCAAGTTTGGATTGGAC
ACCCAAGGATTTGGACCGAATCGTGGTAGCTGAAGGGCCCGGGTAGCTATACAGGCTTGCGAATTGCGGTAGCAACTGC
TAAGACCTTAGCTCACACCCTGAACATCGAGTTGGTTGGTATGTCGAGTCTCTTGGCTCTGGTGCCCCATCAACAAGAA
GGTTTGTTTGTCCCCTTGATGGATGCGCGTCGCAATAATGTTTATGCAGGATTTTATGAAAATGCCAAACCTGTCATGG
CAGAAGCGCACCTATCTTTTGAAGAGGTGCTAGAAAAAGTCAAGGGTACTAGTCAGGTAACCTTTGTCGGAGAAGTTGG
CCCCTGTTGAGCAGATTCAAAAACACTTGCCAAGCACTGATTACAAAGAAACATTGCCCAATGCAGCTAATCTAGCTCT
TTTGGCCTGGGACAAGGAAGCAGACTCCTTGCATGATTTTGTGCCGAATTACCTCAAACGAGTCGAGGCTGAGGAAAAC
TGGCTCAAGAACCATACCGAGTCTGGCGAGTCTTACATTAAACGCCTATGA
4149.3
ATGATAGAAATCAAGCGAATTCAACAACAGCCTGACCTAGCTCAAGCCATCTACGCTGTTATGGCAGCTGTTTACCTAG
TCAGTCCTTGGACTCTGGAGCAAATCCAAGCAGATCTGTCCCAAGACCAGACTTGGTATGCATTGGCTTATGATGGGGC
AGAAGTGATTGGATTTCTAGCTGTGCAGGAGAATCTTTTTGAAGCAGAAGTCCTGCAAATCGCTGTCAAAGGAGCTTAT
CAGGGTCAGGGGATTGCGTCagCCTGTTTGCTCAATTGCCGACAGACAAGGAAATTTTCCTCGAAGTCAGACAGTCAAT
CAACGAGCGCAAGCATTTTACAAGAAAGAAAAGATGACAGTTATCGCTGAGCGAAAGGCCTACTACCATGACCCAGTCG
AGGACGCCATTATCATGAAGAGAGAAATAGATGAAGGATAG
4152.2
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCT
TTTCTACTCAATTGGTGACAAATGGACGGAAGGCCTAGCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGC
TTGATATCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTAT
GATGGTTTCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCT
TTTAGCCCTAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAG
ATAATATCGCTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAA
GTTACTGAGTTTGACCCCAAAAGAATTTGAAAGCGATAAAAATCCGTTTTTTGAAGTTTTCAAAGTTTCGAAAGTAACC
GCCCAATAA
4154.1
ATGACTACTTTTAAAGATGGATTTTTATGGGGGTGGTGCTGTTGCTGCTCATCAACTTGAAGGTGGATGGCAAGAAGGT
GGCAAGGGAATTAGTGTTGCTGATGTTATGACTGCTGGTCGTCATGGAGTAGCTCGTGAAATTACTTTGGGAGTTTTTT
TAGAGGGTAAATATTATCCAAATCATGAGGCGATAGATTTTTATCACCGTTATAAAGAAGATATAGCACTTTTTGCTGA
AATGGGATTCAAGTGCTTCCGTACCTCTATTGCATGGACACGTATCTTTCCAAAAGGTGATGAGTTAGAGCCGAATGAA
GAAGGATTACAGTTTTATGATAATCTTTTTGATGAATGCTTAAAGAATGGTATTGAACCTGTCATCACTCTATCTCATT
TTGAAATGCCTTATCACTTAGTGACCGAATATGGTGGTTGGAAAAATAGGAAATTGATTGATTTCTTTGCTCGTTTTGC
AGAAGTCGTATTTAAACGTTACAAAGATAAGGTTAAATATTGGATGACTTTCAATGAAATCAATAATCAAGCGAATTAT
CAGGAAGATTTTGCACCATTTACTAACTCAGGTATTGTATATGAGGAAGGTGATAATAGAGAAGCAATTATGTATCAAG
CAGCACATTACGAATTAGTTGCTTCTGCACGAGCTGTAAAAATTGGTCATGAGATTAATCCAGATTTTCAAATAGGTTG
TATGATTGCGATGTGTCCAATTTATCCAGTTACTTGCAATCCTAAGGATATCTTAATGGCAATGAAAGCTATGCAGAAG
CGTTATTATTTTGCTGATGTGCATGTTTTAGGTAAATATCCTGAGCATATTTTCAAGTATTGGGAACGAAAAGGTATTT
CAGTTGATTTTACTGCCCAGGATAAAGAAGATTTACTTGGTGGGACTGTAGATTACATTGGTTTCAGTTACTATATGTC
CTTTGCTATCGACTCTCATCGTGAAAATAATCCTTATTTTGATTATCTTGAAACAGAAGATTTAGTGAAAAATAATTAT
GTTAAGGCTTCTGAATGGGAGTGGCAAATTGATCCAGAAGGTTTGCGTTATGCGTTAAATTGGTTTACAGACCACTATC
ACTTACCACTCTTTATTGTTGAAAATGGTTTTGGAGCTATAGATCAAGTTGCAGCAGATGGTATGGTACATGATGATTA
TAGAATTGAATATCTAGGTGCCCATATTCGTGAAATGAAAAAGGCTGTAGTTGAAGATGGTGTTGATTTAATGGGTTAT
ACTCCATGGGGATGTATTGATTTGGTTTCAGCTGGTACCGGTGAAATGCGGAAACGTTATGGCTTTATTTATGTAGATA
AAGATGATAATGGGAAGGGAAGTTATAATCGTTCCCCGAAAAAATCTTTTGGCTGGTATAAGGAAGTTATTTCATCTAA
CGGTGAATCAGTAGAATAG
4154.2
ATGGATCAACAAAACGGGTGTTTGGTTTTCTTGAAAACCATGTTATGGGACCAATGGGCAAACTTGCTCAGTTTAAAGT
AGTACGTGCTATCACGGCTGCAGGTATGGCTGCTGTACCATTTACTATTGTAGGATCAATGTTTTTGGTATTCAGTATT
TTGCCACAAGCTTTCTCATTTTGGCCAATTGTGGCAGATATTTTCTCTGCTTCATTTGATAAATTCACATCACTTTACA
TGGTTGCAAACTATGCGACTATGGGTTCTCTATCTCTTTATTTCGTTCTATCACTTGCATATGAATTGACAAAAATTTA
TGCAGAGGAAGAAGAACTCAATATGAATCCTCTTAATGGTGCCTTGCTTGCCTTGATGCTTTTGTCATGACAGTACCGC
AAATCATTTTTGATGGTGGAATGATGAAGACTGTGACAAGTCTAAAAGAAGGTGCAGTAATTGCAGATGGATGGGCAAT
GGGAAATGTAGTCGCACGTTTTGGGACAACAGGGATTTTTACCGCAATCATTATGGCAATTGTGACTGTTCTTATTTAT
CGTATGTGTGTTAAACATAATTGGGTTATTAAAATGCCTGAAGCTGTTCCAGAAGGAGTTTCTCGTGGATTTACCGCTT
TGGTTCCGGGATTTGTGTTGCATTTGTTGTTATCTTTATCAACGGTCTTCTTGTAGCAATGGGAACAGATATTTTTAAA
GTCATTGCAATTCCATTTGGTTTTGTATCCAATCTGACTAATTCGTGGATTGGTTTAATGATTATTTATCTATTGACTC
AACTACTTTGGATTGTAGGTATCCACGGTGCGAACATTGTTTTTGCATTTGTTAGTCCAATTGCTCTTGCTAACATGGC
TGAAAATGCTGCTGGGCGGGCACTTCGCTGTTGCAGGTGAATTTTCTAATATGTTTGTAATTGCAGGTGGTTCTGGTGC
AACTTTAGGACTATGTTTATATATTGCTTTTGCCTCTAAATCTGAACAGCTTAAAGCAATAGGACGAGCATCTGTAGTT
CCAGCCTTATTTAATATTAATGAACCATTAATTTTTGGATTACCTATTATCTATAATCCAGCCTTGGCTATACCATTTA
TTTTAGCACCAATGGTTACTGCTACTATTTATTACGTAGCGAATTCTCTAAACTTTATTAAGCCAATTATCGCACAGGT
TCCATGGCCAACTCCAGTAGGGATTGGAGCTTTCTTAGGGACAGCAGATCTTCGAGCTGTATTAGTTGCTCTAGTATGT
GCATTTGCAGCATTCCTAGTCTATCTTCCATTCATCCGTGTATATGATCAAAAATTGGTGAAAGAAGAGCAAGGTATCT
AA
4155.1
ATGAAAAAATTTTATGTAAGTCCAATTTTTCCTATTCTAGTAGGATTGATTGCGTTTGGAGTCTTATCCACTTTCATTA
TTTTTGTTAATAATAATCTGTTGACGGTTTTAATTTTGTTTCTTTTTGTAGGAGGCTATGTTTTTTTATTTAAGAAACT
GAGAGTGCATTATACAAGGAGTGATGTAGAACAGATACAGTATGTAAACCACCAAGCGGAAGAAAGTTTGACAGCTCTA
TTGGAACAGATGCCTGTAGGTGTTATGAAATTGAATTTATCTCTGGAGAGGTTGAGTGGTTTAATCCCTATGCTGAATT
GATTTTGACCAAGGAAGATGGTGATTTTGATTTAGAAGCTGTTCAAACGATTATCAAGGCTTCAGTAGGAAATCCGTCT
ACTTATGCCAAGCTTGGTGAGAAGCGTTATGCTGTTCATATGGATGCTTCTTCCGGTGTTTTGTATTTTGTAGATGTAT
CCAGGGAACAAGCCATAACAGATGAATTGGTAACAAGTAGACCAGTGATTGGATTGTCTCTGTGGATAATTATGATGAT
TTGGAGGATGAAACTTCTGAGTCAGATATTAGTCAAATCAATAGTTTTGTAGCTAATTTTATATCAGAGTTTTCAGAAA
AACACATGATGTTTTCTCGTCGGGTAAGTATGGATCGATTTTATCTATTTACTGACTACACGGTGCTTGAGGGCTTGAT
GAATGATAAATTTTCTGTTATTGATGCTTTCAGAGAAGAGTCGAAACAGAGACAGTTGCCCTTGACCTTAAGTATGGGA
TTTTCTTATGGCGATGGAAATCATGATGAGATAGGGAAAGTTGCTTTGCTCAATTTGAACTTGGCTGAAGTACGTGGTG
GCGACCAGGTGGTTGTTAAGGAAAACGACGAAACGAAAAATCCAGTTTATTTTGGTGGTGGGTCTGCTGCTTCAATCAA
GCGTACACGGACTCGTACGCGCGCTATGATGACAGCTATTTCAGATAAGATTCGGAGTGTAGATCAGGTTTTTGTAGTC
GGTCACAAAAATTTAGACATGGATGCTTTGGGCTCTGCTGTAGGTATGCAGTTGTTCGCCAGCAATGTGATTGAAAATA
GGTATGCTCTTTATGATGAAGAACAAATGTCTCCAGATATTGAACGAGCTGTTTCATTCATAGAAAAAGAAGGAGTTAC
GAAGTTGTTGTCTGTTAAGGATGCAATGGGGATGGTGACCAATCGTTCTTGTTGATTCTTGTAGACCATTCAAAGACAG
CCTTAACATTATCAAAAGAATTTTATGATTTATTTACCCAACCATTGTTATTGACCACCATAGAAGGGATCAGGATTTT
CCAGATAATGCGGTTATTACTTATATCGAAAGTGGTGCAAGTAGTGCCAGTGAGTTGGTAACGGAATTGATTCAGTTCC
AGAATTCTAAGAAAAATCGTTTGAGTCGTATGCAAGCAAGTGTCTTGATGGCTGGTATGATGTTGGATACTAAAAATTT
CACCTCGCGAGTAACTAGTCGGACATTTGATGTTGCTAGCTATCTCAGAACGCGCGGAAGTGATAGTATTGCTATCCAG
GAAATCGCTGCGACAGATTTTGAAGAATATCGTGAGGTCAATGAACTTATTTTACAGGGGCGTAAATTAGGTTCAGATG
TACTAATAGCAGAGGCTAAGGACATGAAATGCTATGATACAGTTGTTATTAGTAAGGCAGCAGATGCCATGTTAGCCAT
GTCAGGTATTGAAGCGAGTTTTGTCTGCGAAGAATACACAAGGATTTATCTCTATCTCAGCTCGAAGTCGTAGTAAACT
GAATGTACAACGGATTATGGAAGAGTTAGGCGGTGGAGGCCACTTTAATTTGGCAGCAGCTCAAATTAAAGATGTAACC
TTGTCAGAAGCAGGTGAAAAACTGACAGAAATTGTATTAAATGAAATGAAGGAAAAGGAGAAAGAAGAATGA
4156.1
ATGAAAGAGAAAAATATGTGGAAAGAATTGTTGAATCGTGCAGGCTGGATTTTGGTCTTTTTACTTGCCGTCCTTTTAT
ATCAGGTTCCCCTAGTGGTACCTCTATTTTGACTTTAAAAGAAGTAGCCCTGCTACAGTCAGGGCTGATAGTTGCTGGC
CTTTCAATTGTGGTTCTGGCTCTATTTATTATGGGAGCTCGTAAAACCAAGTTAGCTAGTTTTAATTTTTCTTTTTTTA
GAGCTAAAGATTTGGCACGTTTGGGCTTGAGTTATCTAGTTATTGTCGGGTCAAATATACTTGGTTCCATTTTATTGCA
ACTGTCAAATGAGACGACAACAGCTAACCAGTCTCAGATTAATGATATGGTTCAAAATAGTTCGTTGATTTCCAGTTTC
TTCTTGCTAGCCTTGCTTGCCCGATTTGTGAGGAAATCTTGTGTCGTGGGATTGTTCCTAAAAAGATTTTCCGAGGCAA
GGAGAACTTGGGATTTGTAGTCGGTACGATTGTGTTTGCTTTATTGCATCAACCAAGTAATTTACCTTCTTTATTGATT
TATGGAGGTATGTCGACAGTTCTATCTTGGACAGCCTACAAGACCCAACGTTTGGAAATGTCGATCTTGCTTCACATGA
TTGTTAATGGGATTGCTTTCTGTTTGTTGGCTCTTGTGGTGATTATGAGTCGGACATTAGGAATTTCTGTTTAAATGAA
AGAGAAAAATATGTGGAAAGAATTGTTGAATCGTGCAGGCTGGATTTTGGTCTTTTTACTTGCCGTCCTTTTATATCAG
GTTCCCCTAGTGGTTACCTCTATTTTGACTTTAAAAGAAGTAGCCCTGCTACAGTCAGGGCTGATAGTTGCTGGCCTTT
CAATTGTGGTTCTGGCTCTATTTATTATGGGAGCTCGTAAAACCAAGTTAGCTAGTTTTAATTTTTCTTTTTTTAGAGC
TAAAGATTTGGCACGTTTGGGCTTGAGTTATCTAGTTATTGTCGGGTCAAATATACTTGGTTCCATTTTATTGCAACTG
TCAAATGAGACGACAACAGCTAACCAGTCTCAGATTAATGATATGGTTCAAAATAGTTCGTTGATTTCCAGTTTCTTCT
TGCTAGCCTTGCTTGCTCCGATTTGTGAGGAAATCTTGTGTCGTGGGATTGTTCCTAAAAAGATTTTCCGAGGCAAGGA
GAACTTGGGATTTGTAGTCGGTACGATTGTGTTTGCTTTATTGCATCAACCAAGTAATTTACCTTCTTTATTGATTTAT
GGAGGTATGTCGACAGTTCTATCTTGGACAGCCTACAAGACCCAACGTTTGGAAATGTCGATCTTGCTTCACATGATTG
TTAATGGGATTGCTTTCTGTTTGTTGGCTCTTGTGGTGATTATGAGTCGGACATTAGGAATTTCTGTTTAA
4156.4
ATGGATACACAAAAGATTGAAGCGGCTGTAAAAATGATTATCGAGGCTGTAGGAGAGGACGCTAATCGCGAGGGCTTGC
AGGAAACACCTGCTCGTGTAGCCCGTATGTATCAAGAGATTTTTTCAGGTCTTGGTCAAACAGCAGAGGACATTTGTCA
AAATCCTTTGAAATTATTGACGATAATATGGTGGTAGAAAAGGATATCTTTTTCCATACCATGTGTGAACACCACTTCT
TGCCATTTTATGGTAGAGCGCACATTGCCTACATTCCAGATGGTCGTGTGGCAGGCTTGTCTAAGCTAGCCCGTACGGT
TGAAGTTTATTCGAAAAAACCACAAATTCAAGAACGTTTGAATATCGAAGTGGCCGATGCCTTGATGGACTATCTAGGT
GCTAAAGGAGCCTTTGTTGTCATTGAGGCGGAACATATGTGTATGAGTATGCGTGGTGTTAGAAAACCAGGCACTGCAA
CCTTGACGACAGTAGCTCGTGGTCTATTTGAAACAGATAAGGATCTCCGTGACCAAGCTTATCGTTTAATGGGGCTATAA
4157.2
ATGAAAGACTTGTTTTTAAAGAGAAAGCAGGCCTTTCGTAAGGAGTGTCTTGGTTATCTGCGCTATGTGCTCAATGACC
ACTTTGTCGTTCCTGCTTGTCCTGTTGGGCTTTCTAGCCTACCAGTACAGTCAACTCTTACAACATTTTCCTGAAAATC
ATTGGCCTATCCTTTTGTTTGTAGGAATTACGTCTGTTTTACTTTTACTTTGGGGAGGAACTGCCACCTATATGGAGGC
TCCAGACAAGCTCTTTCTCTTAGTTGGAGAAGAGGAAATTAAGCTCCATCTCAAGCGTCAAACTGGCATTTCCCTAGTC
TTTTGGCTCTTTGTACAGACCCTTTTCTTGCTGTTATTTGCGCCTTTATTTTTAGCAATGGGTTATGGCTTGCCAGTTT
TTCTGCTCTATGTGCTTTTATTGGGGGTAGGAAAATATTTCCACTTTTGTCAAAAGGCCAGCAAATTTTTCACTGAAAC
TGGACTGGACTGGGACTATGTTATTTCTCAAGAAAGCAAGCGTAAGCAAGTCTTGCTTCGTTTCTTTGCCCTCTACGCA
GGTCAAGGGAATTTCAAACAGCGTTAAGCGTCGTGCCTATCTGGACTTTATTTTAAAGGCTGTTCAGAAGGTGCCTGGG
AAGATTTGGCAAAATCTCTATCTGCGTTCTTATCTGCGAAATGGCGACCTCTTTGCTCTCAGTCTCGTCTTCTCTTGCT
TTCCTTGCTGGCGCAGGTTTTTATCGAGCAAGCTTGGATTGCGACAGCAGTGGTAGTTCTCTTTAACTACCTCTTGCTC
TTCCAGTTGCTGGCCCTCTATCATGCCTTTGACTACCAGTATTTGACCCAACTCTTTCCGCTGGACAAGGGGCAAAAGG
AAAAAGGCTTACAGGAGGTAGTTCGAGGATTGACCAGTTTTGTTTTACTTGTGGAATTAGTTGTTGGGTTGATTACCTT
CCAAGAAAAACTAGCCCTTCTAGCCTTACTAGGAGCTGGTTTGGTTTTACTAGTCTTGTATTTGCCTTATCAGGTAAAA
CGTCAGATGCAGGACTAA
4158.1
ATGAGAAAATCAATAGTATTAGCGGCAGATAATGCCTATCTTATTCCTTTAGAGACGACTATAAAGTCTGTATTGTATC
ACAATAGAGATGTTGATTTTTATATTCTCAACAGTGATATAGCTCCTGAATGGTTTAAATTATTGGGGAGAAAAATGGA
AGTTGTGAATTCTACAATTCGCAGTGTACACATTGATAAAGAACTTTTTGAAAGCTATAAAACAGGACCTCATATAAAT
TATGCTCTTACTTTAGATTTTTTGCGACAGAAGTGGTTGAATCTGATAGGGTATTGTATCTGGATTCCGATATCATTGT
AACTGGGGAACTAGCTACTTTGTTTGAGATAGATCTCAAAGGATATTCAATTGGTGCTGTTGATGATGTCTATGCCTAT
GAAGGACGAAAATCTGGATTTAATACTGGTATGTTACTAATGGATGTTGCAAAGTGGAAAGAACATTCTATTGTCAATA
GTATTGGAATTAGCGGCCGAGCAGAATCAAGTTGTTCATCTTGGGGATCAGAGTATTTTAAATATTTATTTTGAGGATA
ATTGGCTAGCCTTAGATAAAACATATAATTATATGGTGGGTATTGATATTTATCACCTTGCTCAAGAATGTGAACGTCT
AGATGACAATCCACCTACAATTGTTCACTATGCTAGTCATGATAAACCTTGGAATACATATAGTATATCTAGACTACGT
GAATTATGGTGGGTTTATAGAGATTTGGATTGGTCAGAGATTGCTTTTCAACGTTCCGATTTAAATTATTTTGAAAGAA
GCAATCAGTCTAAAAAACAAGTGATGCTTGTGACATGGAGTGCAGATATAAAACATTTAGAGTATTTAGTACAACGGTT
ACCTGATTGGCATTTTCATTTGGCTGCACCGTGTGATTGTTCTGAGGAGCTGACCTCTCTATCACAGTATACGAATGTA
ACAGTATATCAAAATGTATTACATAGTAGAATTGATTGGCTATTGGACGATTCTATAGTTTATTTAGATATTAATACAG
GTGGAGAGGTTTTTAATGTAGTTACAAGGGCACAAGAAAGTGGCAAGAAAATCTTCGCTTTTGATATCACACGTAAAAG
TATGGATGATGGACTCTATGACGGTATTTTTTCTGTGGAGAGACCAGATGATTTAGTGGATAGAATGAAGAATATAGAG
ATAGAGTAA
4158.2
ATGACTAAGATTTATTCGTCAATAGCACTAAAAAAAGGACTATTTACCTCATTTCTACTGTTTATCTATGTATTGGGAA
GTCGTATTATTCTCCCTTTTGTTGACCTAAATACTAAAGATTTTTTAGGAGGTTCAACAGCCTATCTAGCCTTCTCAGC
CGCCCTAACAGGTGGGAATCTAAGAAGTTTATCAATTTTTTCTGTTGGATTATCCCCTTGGATGTCCGCCATGATTTTA
TGGCAGATGTTTTCTTTTTCTAAACGGTTGGGTTTAACATCTACGTCTATAGAAATACAAGATCGCCGTAAAATGTACC
TGACCTTGCTAATTGCTGTGATTCAATCCTTGGCAGTTAGCTTGAGACTGCCAGTACAATCCTCCTATTCTGCAATATT
GGTTGTTCTAATGAATACAATATTGCTGATAGCAGGAACATTTTTTCTTGTTTGGTTGTCAGATTTAAATGCGAGTATG
GGGATTGGAGGTTCTATTGTAATCCTCCTATCCAGTATGGTTTTAAATATTCCTCAGGATGTTTTGGAAACATTTCAGA
CAGTACACATTCCAACAGGGATTATTGTGTTACTTGCTTTATTAACCCTTGTCTTTTCTTATTTACTGCCCTTATGTAT
CGAGCTCCCTATTTGGTTCCTGTTAATAAAATTGGCTTACACAATCGATTTAAACGCTATTCTTATCTCGAAATCATGT
TGAATCCTGCAGGTGGGATGCCTTATATGTATGTGATGAGTTTTCTTAGTGTACCAGCTTATTTGTTCATCTTGTTGGG
ATTTATTTTCCCTAATCATTCAGGGTTAGCGGCTTTATCAAAGGAATTTATGGTTGGAAAGCCTTTGTGGGTCTATGTT
TATATTTCGGTCTTATTTTTATTTAGTATCATTTTTGCTTTTGTTACGATGAATGGAGAAGAGATTGCAGACCGTATGA
AAAAATCTGGAGAATACATTTATGGTATTTATCCAGGTGCGGATACTAGTCGATTTATTAATCGATTGGTCCTTCGTTT
CTCAGTCATAGGTGGTCTCTTTAATGTGATTATGGCAGGTGGTCCCATGCTTTTTGTTTTGTTTGATGAAAAGTTATTA
CGATTGGCAATGATTCCAGGCTTATTTATGATGTTCGGGGGCATGATTTTTACGATTAGAGACGAGGTCAAGGCTTTAA
GGCTAAATGAGACCTATAGACCTTTGATTTAG
4158.3
ATGTCCTCTCTTTCGGATCAAGAATTAGTAGCTAAAACAGTAGAGTTTCGTCAGCGTCTTTCCGAGGGAGAAAGTCTAG
ACGATATTTTGGTTGAAGCTTTTGCTGTGGTGCGTGAAGCAGATAAGCGATTTTAGGGATGTTTCCTTATGATGTTCAA
GTCATGGGAGCTATTGTCATGCACTATGGAAATGTTGCTGAGATGAATACGGGGGAAGGTAAGACCTTGACAGCTACCA
TGCCTGTCTATTTGAACGCTTTTTCAGGAGAAGGAGTGATGGTGTGACTCCTAATGAGTATTTATCAAAGCGTGATGCC
GAGGAATGGGTCAAGTTATCGTTTTCTAGGATTGACCATTGGTGTACCATTTACGGAAGATCCAAAGAAGGAGATGAAA
GCTGAAGAAAAGAAGCTTATCTATGCTTCGGATATCATCTACACAACCAATAGTAATTTAGGTTTTGATTATCTAAATG
ATAACCTAGCCTCGAATGAAGAAGGTAAGTTTTTACGACCGTTTAACTATGTGATTATTGATGAAATTGATGATATCTT
GCTTGATAGTGCACAAACTCCTCTGATTATTGCGGGTTCTCCTCGTGTTCAGTCTAATTACTATGCGATCATTGATACA
CTTGTAACAACCTTGGTCGAAGGAGAGGATTATATCTTTAAAGAGGAGAAAGAGGAGGTTTGGCTCACTACTAAGGGGG
CCAAGTCTGCTGAGAATTTCCTAGGGATTGATAATTTATACAAGGAAGAGCATGCGTCTTTTGCTCGTCATTTGGTTTA
TGCGATTCGAGCTCATAAGCTCTTTACTAAAGATAAGGACTATATCATTCGTGGAAATGAGATGGTACTGGTTGATAAG
GGAACAGGGCGTCTAATGGAAATGACTAAACTTCAAGGAGGTCTCCATCAGGCTATTGAAGCCAAGGAACATGTCAAAT
TATCTCCTGAGACGCGGGCTATGGCCTCGATCACCTATCAGAGTCTTTTTAAGATGTTTAATAAGATATCTGGTATGAC
AGGACAGGTAAGGTCGCGGAAAAAGAGTTTATTGAAACTTACAATATGTCTGTAGTACGCATTCCAACCAATCGTCCGA
GACAACGGATTGACTATCCAGATAATCTATATATCACTTTACCTGAAAAAGTGTATGCATCCTTGGAGTACATCAAGCA
ATACCATGCTAAGGGAAATCCTTTACTCGTTTTTGTAGGCTCAGTTGAAATGTCTCAACTCTATTCGTCTCTCTTGTTT
CGTGAAGGGATTGCCCATAATGTCCTAATGCTAATAATGCGGCGCGTGAGGCTCAGATTATCTCCGAGTCAGGTCAGAT
GGGGGCTGTGACAGTGGCTACCTCTATGGCAGGACGTGGTACGGATATCAAGCTTGGTAAAGGAGTCGCAGAGCTTGGG
GGCTTGATTGTATTGGGACTGAGCGGATGGAAAGTCAGCGGATCGACCTACAAATTCGTGGCCGTTCTGGTCGTCAGGG
AGATCCTGGTATGAGTAAATTTTTTGTATCCTTAGAGGATGATGTTATCAAGAAATTTGGTCCATCTTGGGTGCATAAA
AAGTACAAAGACTATCAGGTTCAAGATATGACTCAACCGGAAGTATTGAAAGGTCGTAAATACCGGAAACTAGTCGAAA
AGGCTCAGCATGCCAGTGATAGTGCTGGACGTTCAGCACGTCGTCAGACTCTGGAGTATGCTGAAAGTATGAATATACA
ACGGGATATAGTCTATAAAGAGAGAAATCGTCTAATAGATGGTTCTCGTGACTTAGAGGATGTTGTTGTGGATATCATT
GAGAGATATACAGAAGAGGTAGCGGCTGATCACTATGCTAGTCGTGAATTATTGTTTCACTTTATTGTGACCAATATTA
GTTTTCATGTTAAAGAGGTTCCAGATTATATAGATGTAACTGACAAAACTGCAGTTCGTAGCTTTATGAAGCAGGTGAT
TGATAAAGAACTTTCTGAAAAGAAAGAATTACTTAATCAACATGACTTATATGAACAGTTTTTACGACTTTCACTGCTT
AAAGCCATTGATGACAACTGGGTAGAGCAGGTAGACTATCTACAACAGCTATCCATGGCTATCGGTGGTCAATCTGCTA
GTCAGAAAAATCCAATCGTAGAGTACTATCAAGAAGCCTACGCGGGCTTTGAAGCTATGAAAGAACAGATTCATGCGGA
TATGGTGCGTAATCTCCTGATGGGGCTGGTTGAGGTCACTCCAAAAGGTGAAATCGTGACTCATTTTCCATAA
4158.4
ATGATAGGGACTTTCGCCGCTGCTCTTGTAGCTGTACTAGCAAATTTCATCGTCCCTATTGAAATTACCCCAATAGTGC
CAATACTGAAATTGCACCACCAGATGGGATTGGGCAGGTTCTCAGCAACCTCTTGCTCAAACTGGTTGACAACCCAGTC
AACGCCCTGCTTACTGCTAACTATATTAGAATCTTATCTTGGGCAGTCATTTTTGGAATCGCTATGAGAGAAGCCAGTA
AAAATAGTCAAGAATTGCTAAAAACTATCGCTGACGTGACTTCTAAAATTGTCGAATGGATCATCAATCTGGCTCCATT
TGGAATCCTGGTCTTGTTTTTAAAACCATTTCTGACAAGGGAGTCGGAAGCCTTGCCAACTACGGTATTTTATTGGTTC
TATTAGTAACGACTATGCTTTTTGTTGCCCCTGTGGTCAACCCTTTGATTGCCTTCTTCTTTATGAGACGCAATCCTAC
CCTCTAGTTTGGAACTGCCTCCGTGTCAGCGGTGTGACAGCCTTTTTCACTCGTAGTTCTGCGACTAACATTCCTGTCA
ACATGAAACTCTGCCATGACCTTGGACTCAACCCAGATACCTATTCTGTTTCTATCCCACTCGGTTCTACTATCAATAT
GGCTGGAGTAGCGATTACCATTAACCTTTTTGACCCTTGCTGCAGTTAACACTCTTGGAATTCCTGTTGACTTGCCACA
GCCTTTTGTCCTCAGTGTGGTAGCAGCTATCTCATCCTGTGATGCTTCAGGTATTGCCGGAGGTTCCCTCCTTCTTATC
CCAGTTGCTTGTAGCCTTTTCGGTATTTCTAACGATATTGCCATACAAATTGTTGGGGTTGGTTTTGTGATTGGTGTCA
TCCAAGACTCATGTGAAACACCCCTTAACTCTTCTACAGATGTCCTCTTTACCGCCGTTGCCGAATACGCAGCAACCCG
TAAAAAATAA
4158.3
ATGTCTATTAGCCAACGTACGACCAAGCTCATCTTAGCTACCTGTCTTGCCTGCCTGCTTGCTTATTTTTCTCAATCTT
TCGTCAGCAGTTTCGGCTGGAATTATCGCTCTCTTGAGCCTATCTGATACGCGTAGAAGTACTTTAAAACTGGCTCGCA
ATCGTCTTTTTTCTATGCTCTAGCTCTGGCTATCGGTGTTCTAGCTTTTCACTTGAGCGGATTTCATATCTGGAGTCTC
GGCCTCTATCTGGCCTCTACGTTCCTTTAGCCTACAAGATGGGCTGGGAAATTGGCATCACACCAAGCACTGTTTTGGT
TAGCCATCTCTTGGTTCAAGAGTCAACCTCTCCAGACCTTTAGTCAATGAATTCCTTCTCTTTGCTATTGGTACAGGAT
TTGCCTTGCTTGTTAATCTCTATATGCCTTCACGAGAAGAGGAAATCCAGCACTACCACACGCTGGTGGAAGAAAAGTT
AAAAGATATCCTCCAGCGCTTCAAATACTATTTATCCAGAGGAGACGGACGCAACCGAGCACAGCTGGTAGCAGAATTA
GACACGCTTTTGAAAGAAGCCCTCAGACTGGTCTATTTGGATCACTCTGACCACCTCTTTCACCAGACAGACTACCATA
TCCACTACTTTGAGATGAGACAGCGACAAAGTCGTATCCTGAGAAACATGGCCCAACAGATTAACACTTGTCACCTTGC
CGCCAGTGAAAGCCTGATCTTAGCGCAACTCTTTTCAAAAATTGCAGGTCAACTGAGCCAGACCAATCCTGCTTCTGAT
TTGCTAGATGAAATTGAACGTTATCTGGAAGTCTTCCGGAACCGCAGTCTGCCCAAGACAAGAGAAGAATTTGAAACCC
GCGCCACCCTTCTTCAACTCCTACGTGAAGCCAAAACCTTCATCCAAGTAAAAGTTGATTTTTACCAAAAATATAGACA
GTAA
4158.6
ATGGAAATCATGTCGCTGCGATTGCTGTTTTTGCCGTCATCATTGGTTTAGTCATTGGATATGTCAGCATCTCAGCTAA
GATGAAATCATCTCAGGAAGCTGCAGAGTTGATGCTTTTAAATGCTGAACAAGAAGCAACTAATTTACGTGGACAAGCT
GAGCGTGAAGCGGATTTACTTGTTAATGAAGCCAAACGTGAAAGCAAGTCTCTTAAAAAAGAAGCACTATTGGAGGCCA
AAGAAGAAGCCAGAAAATACCGTGAAGAAGTGGACGCTGAATTCAAATCAGAACGTCAAGAACTCAAACAAATCGAAAG
TCGTTTGACAGAGAGAGCTACTAGCCTTGACCGTAAGGACGACAATTTGACGAGTAAAGAACAAACACTTGAACAAAAA
GAACAAAGTATTTCTGATAGAGCGAAAAACCTTGATGCGCGTGAAGAGCAATTAGAGGAAGTCGAAAGACAAAAAGAAG
CAGAACTAGAGCGTATTGGTGCGCTGTCTCAGGCAGAAGCACGAGATATTATCTTGGCTCAGACAGAGGAAAACTTGAC
CAGGGAGATTGCCAGTCGCATTCGCGAAGCTGAGCAAGAGGTCAAGGAACGTTCTGACAAAATGGCCAAGGACATCTTG
GTTCAAGCTATGCAACGTATCGCTGGTGAATATGTAGCGGAGTCAACAAACTCAACAGTTCATCTGCCAGACGATACTA
TGAAGGGACGCATTATTGGTCGTGAAGGTCGTAACATTCGTACCTTTGAAAGTTTGACAGGGGTCGATGTGATTATCGA
CGATACACCAGAAGTGGTGACCTTGTCAGGATTTGATCCGATTCGTCGTGAGATTGCCCGTATGACTATGGAAATGTTG
CTCAAAGATGGTCGTATACATCCAGCTCGTATCGAAGAGTGGTTGAGAAAAACCCGTCAAGAGATTGACAATAAGATTC
GTGAATACGGTGAGGCTGCTGCCTATGAAATTGGTGCGCCAAACCTCATCCAGACTTGATGAAGATTATGGGACGTTTG
CAGTTCCGTACTTCATATGGACAAAATGTTTTGCGCCATTCGATTGAGGTTGCTAAGTTGGCTGGTATCATGGCGAGCG
AACTTGGTGAAAATGCGGCTCTTGCCCGTCGTGCTGGATTCCTTCACGATATCGGGAAAGCCATTGACCATGAGGTTGA
AGGTAGCCACGTTGAAATCGGTATGGAATTGGCCCGTAAGTACAAGGAACCCCCAGTTGTGGTGAATACGATTGCTAGT
CACCACGGAGATGTTGAAGCTGAGAGCGTGATAGCAGTTATCGTCGCTGCAGCAGATGCCTTGAGCGCAGCCCGTCCAG
GTGCTCGTAGTGAGTCTCTTGAAAGCTACATCAAGCGTCTCCATGATTTGGAAGAAATTGCTAACGGCTTTGAAGGAGT
GCAAACTAGCTTTGCCCTTCAAGCAGGACGTGAAATTCGTATCATGGTCAATCCAGGAAAAATCAAGGACGACAAAGTC
ACAATCTTGGCTCACAAAGTTCGTAAGAAAATTGAAAACAATCTCGATTATCCAGGAAATATCAAGGTAACCGTGATTC
GCGAGCTTCGTGCAGTAGATTATGCTAAATAA
4158.7
ATGATGTTAAAACCCTCTATTGATACCTTGCTCGACAAGGTTCCTTCAAAATATTCACTCGTAATCTTGGAAGCAAAAC
GTGCCCACGAATTGGAAGCAGGTGCCCCAGCAACTCAAGGTTTCAAGTCTGAAAAATCAACTCTTCGCGCTTTAGAAGA
AATCGAATCAGGAAACGTTACAATTCACCCAGATCCAGAAGGAAAACGTGAAGCAGTGCGTCGCCGTATCGAAGAAGAA
AAACGCCGCAAAGAAGAAGAAGAAAAGAAAATCAAAGAGCAAATTGCTAAAGAAAAAGAAGATGGTGAAAAAATTTAA
4161.1
ATGTCAGCATATCAATTACCGACCGTATGGCAGGATGAAGCTAGTAATCAAGGAGCTTTTACGGGGCTAAACAGACCAA
CAGCAGGTGCCCGTTTCGAACAAAACTTGCCAAAAGGAGAACAAGCTTTTCAGCTTTATTCACTGGGAACACCAAATGG
TGTGAAGGTTACTATCTTATTGGAAGAATTACTAGAAGCTGGTTTTAAGGAAGCGGCTTACGACTTGTATAAGATTGCT
ATCATGGATGGGGATCAATTCGGATCAGACTTTGTGAAGCTCAATCCAAATTCCAAGATTCCAGCCTTATTGGACCAGT
CAGGTACTGAAAACGTAAGAGTCTTTGAGTCTGCTCATATTCTTCTTTACCTTGCTGAGAAATTTGGAGCCTTTTACCA
AGTAATCCTGTGGAAAAGGTAGAAGTTTTGAATTGGCTATTCTGGCAAGCAGGTGCAGCACCTTTTCTAGGTGGGGGAT
TGGACATTTCTCAATTATGCTCCTGAAAAATTGGAATATCCTATTAACCGTTTTACGATGGAAGTGAAACGCCAGTTGG
ATTTATTGGATAAGGAATTGGCTCAGAAACCTTATATTGCAGGCAATGACTATACGATTGCAGATATTGCTATCTGGTC
GGTATGGACAGTTAGTTCAAGGAAATCTTTACCAAGCTTCTGCAAAATTCTGGATGCCTCAAGTTATCAAAATCTAGTA
AAATGGGCAGAAAAAATTGCCAATCGTCCAGCTGTTAAGCGTGGCTTGGAAGTAACTTATACAGAAATTAAATAG
4161.2
TTGGCAAGCTTGATCACTCTATCATCATGTTCTATGTCGGTCGATGTTCTAAGAGATACCATTCAAAAGATTCTCAGTC
GGGAAGAAACGGTCATTGATCCTTGGTGCAACTCTAGGAATCATTTCTGCAGCGATTATGTTTGTGGTCTATCTCTACA
ATACTCGCCTCAGTAAGAAATCCAACTCCAATGCGCTGAAGGCAGCTGCTAAGGACAATCTTTCTGACGCGTTACCTCA
CTTGGAACCGCCATTGCCATCCTAGCTAGTAGTCAATTATCCGATTGTGGATAAACTGGTTGCTATCATCATCACTTTC
TTTATCTTGAAGACTGCCTATGATATCTTCATCGAGTCTTCCTTTAGTCTTTCAGATGGCTTTGACGACCGCCTGCTCG
AGGACTACCAAAAGGCTATCATGGAAATTCCCAAAATCAGCAAGGTCAAATCGCAAAGAGGTCGCACCTACGGTAGCAA
CATCTACCTGGATATTACACTAGAGATGAATCCTGACTTGTCTGTTTTTGAAAGCCATGAAATCGCGGATCAGGTCGAG
TCTATGCTGGAGGAGCGTTTTGGCGTCTTTGATACCGATGTCCATATCGAACCAGCACCTATCCCTGAGGATGAAATTT
TAGACAATGTCTATAAAAAATTGCTTATGCGTGAACAATTGATTGACCAAGGAAACCAACTAGAAGAACTCTTGACTGA
TGGATTTTGTCTATATTCGCCAAGATGGAGAGCAGATGGATAAAGAGGCTTATAAGACCAAAAAAGAGTTAAATTCTGC
TATCAAGGACATTCAAATTACTTCCATCAGTCAAAAAACCAAACTCATCTGCTATGAGTTAGATGGTATCATCCATACC
AGTATCTGGCGTCGCCACGAAACCTGGCAAAATATCTTTCATCAAGAAACCAAAAAAGAATAG
4162.1
ATGACAATTAAACTAGTAGCAACGGATATGGACGGAACCTTCCTAGATGGGAATGGACGCTTTGATATGGATCGTCTCA
AGTCTCTCTGGTTTCCTACAAGQAAAAAGGGATTTACTTTGCGGTAGCTTCGGGTCGGGGATTTCTGTCTCTAGAAAAA
TTATTTGCTGGTGTTCGTGATGACATTATTTTCATCGCGGAAAATGGCAGTTTGGTAGAGTATCAAGGTCAGGACTTGT
ATGAAGCGACTATGTCTCGTGACTTTTATCTGGCAACTTTTGAAAAGCTGAAAACTTCACCTTATGTAGATATCAATAA
ACTGCTCTTGACGGGTAAGAAGGGTTCATATGTTCTAGATACGGTTGATGAGACCTATTTGAAAGTGAGTCAGCACTAT
AATGAAAATATCCAAAAAGTAGCGAGTTTGGAAGATATCACAGATGACATTTTCAAATTTACAACCAACTTCACAGAAG
AACGCTGGAAGATGGGGAGGCTTGGGTAAACGAAAACGTTCCTGGTGTTAAGGCCATGACAACTGGCTTTGAATCCATT
GATATTTGTTCTGGACTATGTCGATAAGGGAGTGGCCATTGTTGAATTAGTTAAAAAACTGGTATCACAATGGATCAGG
TCATGGCTTTTGGAGACAATCTTAATGACTTACATATGATGCAGGTTGTGGGACATCCTGTAGCTCCTGAAAATGCACG
ACCTGAAATTTTAGAATTAGCAAAGACTGTGATTGGTCACCATAAGGAACGGTCGGTTATAGCTTATATGGAGGGCTTA
TAA
4162.2
ATGGCAGATATAAAATTGATTGCATTGGACTTGGACGGGACCTTGCTGACTACTGATAAAAGGCTGACGGATCGTACCA
AGGAAACCTTGCAAGCTGCGCGTGATCGTGGTATCAAGGTCGTATTGACAACTGGTCGTCCCTTAAAAGCCATGGATTT
CTTTCTCCATGAGTTAGGGACTGACGGTCAGGAAGATGAGTATACCATTACTTTAATGGTGGATTAGTTCAGAAAAATA
CAGGAGAAATCCTTGATAAAACAGTCTTTTTCATATGATGATGTGGCACGTTTGTATGAAGAAACAGAGAAATTATCAC
TGCCTCTTGATGCCATCTCAGAAGGAACAGTTTATCAAATCCAATCGGACCAAGAAAGTCTTTATGCCAAATTCAATCC
AGCTTTGACCTTTGTTCCAGTGGACTTTGAAGACTTATCTAGTCAAATGACCTACAACAATGCGTGACGCCTTTGCTCA
AGAACCCTTGGATGCAGCCATTCAGAAGATTTCTCCAGAATTGTTTGACCAATATGAAATCTTTAAATCACGTGAAATG
TTGCTAGAATGGTCACCAAAGAATGTTCATAAAGCAACAGGTTTGGCAAAACTAATCAGCCATCTTGGAATCGACCAAA
GTCAAGTGATGGCTTGTGGTGACGAGGCCAATGACCTCTCTATGATTGAATGGGCAGGTCTTGGTGTTGCTATGCAAAA
CGCTGTTCCTGAAGTAAAGGCAGCCGCAAATGTAGTGACGCCGATGACCAACGATGAGGAAGCTCTTCGCCTGGGCTAT
CGAAGAATATGTGCTAAAGGAGAACTAA
4164.2
ATGGAAAGTTTACTTATTCTATTATTAATTGCCAATCTAGCTGGTCTCTTTCTGATTTGGCAAAGGCAGGATAGGCAGG
AGAAACACTTAAGTAAGAGCTTGGAGGATCAGGCAGATCATTTGTCAGACCAGTTGGATTACCGCTTTGACCAAGCCAG
ACAAGCCAGCCAGTTAGACCAAAAAGATTTGGAAGTGGTTGTCAGCGACCGTTTGCAAGAAGTGCGGATTGAATTGCAC
CAAGTCTGACCCAAGTCCGTCAAGAAATGACAGATAATCTCCTCCAAACTAGAGACAAGACAGACCAACGTCTCCAAGC
CTTGCAGGAATCAAATGAGCAACGTTTGGAACAAATGCGCCAGACGGTCGAGGAAAAACTAGAAAAGACCTTGCAGACA
CGCTTACAGGCTTCCTTTGAGACAGTTTCTAAACAACTGGAGTCTGTCAATCGTGGCCTTGGAGAAATGCAGACAGTTG
CCCGTGATGTCGGAGCTCTTAACAAGGTTCTCTCTGGAACCAAGACGCGAGGGATTCTGGGAGAATTGCAACTGGGGCA
AATTATTGAAGACATCATGACACCTGCCCAGTACGAACGAGAATACGCAACGGTTGAAAACTCTAGTGAACGAGTGGAG
TATGCCATCAAGTTACCCGGACAAGGCGACCAAGAATACGTCTATCTGCCAATTGACTCTAAGTTTCCACTGGCAGATT
ATTACCGCTTGGAAGAAGCCTATGAGACAGGTGACAAGGATGAGATTGAACGCTGTCGTAAGTCACTCCTAGCAAGCGT
CAAGCGCTTTGCTAGGGATATTAGGAACAAGTACATAGCACCACCTCGGACGACCAATTTTGGAGTTTTGTTTGTTCCG
ACAGAAGGTCTCTACTCAGAAATCGTCCGCAATCCGGTCTTCTTTGATGATTTGAGACGGGAAGAACAGATTATTGTTG
CAGGACCAAGTACCCTATCAGCCCTTCTTAACTCCCTATCAGTTGGTTTCAAGACCCTTAATATCCAAAAGAGTGCCGA
CCATATCAGCAAGACTCTTGCCAGTGTCAAGACCGAGTTTGGCAAGTTTGGTGGTATTCTGGTCAAGGCACAAAAACAT
CTCCAACATGCCTCTGGCAATATTGATGAATTATTAAACCGTCGTACCATAGCTATCGAGCGGACGCTCCGTCACATTG
AGTTGTCAGAAGGTGAGCCTGCGCTTGATCTACTCCATTTTCAAGAAAATGAGGAAGAATATGAAGATTAG
4164.3
ATGAAGATTAGTCACATGAAAAAAGATGAGTTATTTGAAGGCTTTTACCTAATCAAATCAGCTGACCTGAGGCAAACTC
GAGCTGGGAAAAACTACCTAGCCTTTACCTTCCAAGATGATAGTGGCGAGATTGATGGGAAGCTCTGGGATGCCCAACC
TCATAACATTGAGGCCTTTACCGCAGGTAAGGTTGTCCACATGAAAGGACGCCGAGAAGTTTATAACAATACCCCTCAA
GTCAATCAAATTACTCTCCGCCTGCCTCAAGCTGGTGAACCCAATGACCCAGCTGATTTCAAGGTCAAGTCACCAGTTG
ATGTCAAGGAAATTCGTGACTACATGTCGCAAATGATTTTCAAAATTGAAAATCCTGTCTGGCAACGGATTGTCCGAAA
TCTCTACACCAAGTATGATAAGGAATTCTACTCCTATCCAGCTGCCAAGACCAACCACCATGCCTTTGAAACGGGCTTG
GCCTATCATACGGCGACCATGGTGCGTTGGCAGACGCTATTAGCGAAGTTTATCCTCAGCTCAATAAGAGCCTGCTCTA
TGCGGGGATTATGTTGCATGACTTAGCTAAGGTCATCGAGTTGACGGGGCCAGACCAGACAGAGTACACAGTGCGAGGT
AATCTTTCTTGGACATATCGCTCTCATTGATAGCGAAATTACCAGACAGTTATGGAACTCGCCATCGATGATACCAAGG
AAGAAGTCGTTTTGCTTCGTCATGTCATCCTCAGTCACCACGGCTTGCTTGAGTATGGAAGCCCAGTCCGTCCACGCAT
TATGGAAGCAGAGATTATCCATATGATTGACAATCTGGATGCAAGCATGATGATGATGTCAACAGCTCTTGCTTTGGTG
GATAAAGGAGAGATGACCAATAAAATCTTCGCTATGGATAATCGTCCCTATAAACCAGATTTAGATTAA
4166.2
ATGAGTGAAAAAGCTAAAAAAGGGTTTAAGATGCCTTCATCTTACACCGTATTATTGATAATCATTGCTATTATGGCAG
TGCTAACTTGGTTTATCCCTGCGGGGGCCTTTATAGAAGGTATTTACGAGACTCAGCCTCAAAATCCACAAGGGATTTG
GGATGTCCTCATGGCACCGATTCGGGCTATGCTAGGTACTCATCCAGAGGAAGGTTCGCTCATTAAAGAAACGAGCGCA
GCGATTGATGTAGCCTTCTTCATCCTTATGGTTGGTGGTTTCCTTGGCATTGTCAACAAAACTGGTGCTCTTGACGTAG
GGATTGCCTCTATCGTGAAGAAGTATAAGGGCCGCGAAAAAATGTTAATTTTGGTACTGATGCCTTTGTTTGCCCTCGG
TGGTACAACTATGGTATGGGTGAAGAAACAATGGCCTTCTATCCACTCCTTGTGCCAGTTATGATGGCCGTTGGTTTTG
ATAGCCTGACTGGTGTTGCAATTATTTTGCTCGGTTCTCAAATCGGCTGTTTGGCATCTACTCTGAATCCATTTGCGAC
AGGTATTGCTTCAGCGACTGCGGGAGTTGGTACAGGGGACGGTATCGTACTTCGTCTGATCTTCTGGGTTACCTTGACT
GCTCTTAGTACTTGGTTTGTTTACCGTTATGCGGATAAGATTCAAAAAGATCCGACTAAGTCACGGTTTATAGTACTCG
CAAAGAAGATTTGAAACACTTTAACGTAGAAGAATCTTCATCTGTAGAATCTACACTAGCAGCAAACAAAAATCAGTTC
TCTTCTTATTGTGTTGACATTCATCTTGATGGTATTGAGCTTCATTCCATGGACAGACCTTGGCGTTACCATTTTTGAT
GACTAATACTTGGTTGACTGGTCTTCCAGTTATTGGTAATATTGTCGGTTCATCTACTCTGCACTAGGTACTTGGTACT
CCCAGAAGGCGCAATGCTCTTTGCCTTTATGGGTATCCTGATTGGTGTTATTTATGGTCTTAAAGAAGATAAGATTATC
TCTTCCTTCATGAATGGTGCTGCTGACTTGCTCAGTGTTGCCTTGATCGTAGCGMTGCTCGTGGTATTCAAGTTATCAT
GAACGACGGTATGATTACCGATACAATCCTCAACTGGGGTAAGAAGGCTTGAGCGGTCTATCTTCACAAGTCTATCGTT
GTAACTTATATATCTTCTATCTACCTATGTCATTCTTGATCCCATCTTCATCTGGTCTTGCCAGCGCAACTATGGGTAT
CATGGCTCCACTTGGAGAATTTGTAAATGTCCGTCCTAGCTTGATTATCACTGCTTACCAATCTGCTTCAGGTGTCTTG
AACTTGATTGCACCAACATCTGGTATTGTGATGGGAGCTCTTGCACTTGGACGTATCAACATTGGTACTTGGTGGAAAT
TCATGGGCAAACTCGTAGTCGCTATTATTGTAGTGACCATCGCCCTTCTTCTCCTTGGAACCTTCCTTCCATTCCTATAA
4166.3
ATGAAAATAGATATAACAAATCAAGTTAAAGATGAATTTTCTTTATATCATTAAAAACCTGATTTCCTATCCTTCAGTA
CTCAATGAAGGAGAAAATGGAACACCTTTTGGACAAGCAATCCAAGATGTCCTAGAAAAAACTTTAGAGATTTGTCGAG
ACATAGGTTTCACTACCTATCTTGACCCTAAAGGTTATTACGGATATGCAGAAATCGGTCAGGGAGCAGAGCTTCTGGC
CATTCTCTGTCATTTGGATGTTGTTCCATCAGGTGATGAAGCAGATTGGCAGACACCGCCATTTGAAGCAACTATCAAA
GACGGCTGGGTATTCGGACGTGGTGTCCAAGATGATAAAGGCCCTTCGCTCGCAGCTGAGGATGCAGTAAAAAGCTTGC
TGGACCAGGTATTCAGTTCAAAAAGCGCGTACGCTTTATCTTTGGTACCGATGAGGAAACCCTCTGGCGCTGCATGGCA
CGCTACAATACCATCGAAGAACAGGCCAGTATGGGCTTTGCACCTGACTCATCTTTTCCTCTGACCTATGCTGAAAAAG
GGCTTCTACAGGTCAAACTTCATGGCCCTGGATCGGATCAACTAGAGCTTGAAGTAGGAGGCGCCTTTAACGTTGTACC
AGACAAGGCCAACTACCAAGGTCTCCTCTATGAACAGGTTTGTAACGGTCTCAAAGAAGCTGGTTATGATTACCAAACC
ACTGAACAAACCGTAACGGTTCTCGGAGTGCCAAAGCATGCTAAGGATGCTAGTCAAGGTATCAATGCGTCATCCGACT
AGCTACCATTCTTGCTCCTCTCCAAGAACACCCTGCTCTCAGTTTTCTTGCAACACAAGCAGGTCAAGACGGCACAGGA
AGACAAATCTTTGGTGATATAGCAGATGAACCTTCTGGTCACCTATCCTTTAATGTCGCAGGTCTCATGATCAATCATG
AACGTTCTGAAATCCGTATTGACATTCGGACTCCTGTCTTTAGCTGACAAGGAAGAACTAGTAGAGTTGCTTACAAGAT
GTGCACAAAACTACCAACTCCGCTACGAAGAGTTTGACTATCTAGCGCCTCTATACGTCGCAGAAGACAGTAAACTCGT
TAGCACACTGATGCAAATCTACCAAGAAAAGACTGGCGATAACAGTCCTGCTATTTCATCCGGTGGTGCCACTTTTGCT
CGCACCATGCCAAATTGTGTAGCCTTCGGCGCCTTATTCCCAGGAGCGAAGCAGACAGAACATCAGGCAAATGAATGTG
CCGTTCTAGAAGATTTGTACCGTGCTATGGATATTATGCCGAAGCCGTCTATCGACTTGCAACTTAA
4169.1
ATGTCTAATTCATTGTCAAGTGTTAGTCTCTCAATTATTTGCAAATTTAGCAGATATTTTCTTTAGAGTAACAATCATT
GCTAACATATACATTATTTCAAAATCAGTAATTGCCACATCACTAGTTCCTATCTTAATAGGAATATCCTCTTTTGTTG
CGAGTCTTTAGTTCCGTTGGTTACTAAAAGGTTAGCGCTAAATAGGGTTTTATCTTTATCTCAATTTGGAAAGACTATA
TTATTGGCGATACTGGTAGGAATGTTTACCGTAATGCAATCCGTAGCGCCTTTGGTGACCTATCTATTTGTTGTTGCAA
TTTCCATACTAGATGGTTTTGCAGCACCCGTTTCCTATGCTATTGTGCCACGCTATGCGACCGATTTGGGTAAGGCTAA
TTCAGCCTTATCAATGACTGGTGAAGCTGTTCAATTGATAGGTTGGGGATTAGGTCCACTCTTGTTTGCAACAATTGGT
CGTTACCTACCACGTGTATCAATTTAGTCTGTATATCATTTCTAGCTTTTCTGATGTTATTTCTTCCTAACGCTGAAGT
GGAGGTGTTAGAGTCAGAAACTAATCTTGAAATTTTGCTCAAAGGTTGGAAGTTAGTTGCTAGAAATCCTAGATTAAGA
CTTTTTGTATCAGCAAATTTATTGGAAATTTTTTCAAAATACGATTTGGGTTTCTTCCATTATACTTGTTTTTTGTAAC
GGAGTTATTAAATAAAACGGAAAGTTACTGGGGATATTCTAATACAGCATACTCTATTGGTATTATAATTAGTGGCTTA
ATTGCTTTTAGGCTATCTGAAAAGTTCCTTGCTGCTAAATGGGAACCCCAATTATTCACCCCAAATCTAAAAACCATCC
AGAATCCTTGCCTTAGCTTAGATCCTAGATGGTTTCTTTTTTCACCCAATGGGTGTTTTTTACTAGACAAAAAAGAGTT
TCCCCTTTATGGTATAAGTGTAGAAAAAAACACAAAAAGAAAGGAAACTCACATGAACAGTTTACCAAATCATCACTTC
CAAAACAAGTCTTTTTACCAACTATCTTTCGATGGAGGTCATTTAACCCAGTATGGTGGTCTTATCTTTTTTCAGGAAC
TTTTTTCCCAGTTGAAACTAAAAGAGCGGATTTCTAAGTATTTAGTAACGAATGACCAACGCCGCTACTGTCGTTATTC
GGATTCAGATATCCTTGTCCAGTTCCTCTTTCAACTGTTAACAGGTTATGGAACGGACTATGCTTGTAAAGAATTGTCA
GCTGATGCCTACTTTCCAAAATTGTTGGAAGGAGGGCAGCTTGCTTCACAGCCAACCTATCCCGTTTTCTTTCCAGAAC
TGACGAGGAAACAGTCCATAGTTTGCGATGCCTCAACCTTGAATTGGTCGAATTCTTTTTACAGTTTCACCAGCTAAAC
CAACTCATTGTAGATATCGATTACCCATTTCACAACTTATGGCAAGCAAGAAGGTGTTGCTTATAACGCCCACTATCGT
GCTCATGGCTATCATCCTCTTTATGCTTTCGAGGGGAAGACAGGTTATTGTTTCAATGCCCAGCTTCGTCCTGGTAATC
GTTATTGTTCTGAAGAGGCAGACAGCTTTATCACACCTGTTTTAGAACGCTTTTAATCAACTTCTCTTTCGAATGGATA
GTGGCTTTGCGACCCCAAAATTATACGATTTAATTGAAAAAACAGGGCAATACTACCTCATAAAACTCAAGAAAAATAC
TGTCTGAGCCGTCTGGAGACCTTTCCCTCCCTTGCCCACAGGATGAGGACTTTAACCATCTTGCCCCACTCCGCCTACT
CAGAAACCTCTATCAAGCAGGATCTTGGTCGCACAAGCGTCGTGTCTGCCAGTTCTCTGAACGAAAAGAAGGAAACTGT
TCTACGATGTTATTTCTCTCGTTACAAATATGACGAGTGGAACAAGCCAAGACCAGTTTCAGCTTTATCGTGGACGTGG
TCAAGCCGAGAATTTCATCAAGGAGATGAAGGAGGGATTTTTTGGCGATAAAACGGATAGTTCAACCTTAATCAAAAAC
GAAGTTCGTATGATGATGAGCTGTATCGCCTACAATCTCTATCTTTTTCTCAAACATCTAGCTGGAGGTGACTTCCAAA
CTTTAACAATCAAACGCTTCCGCCATCTTTTTCTTCACGTGGTGGGAAAATGTGTTCGAACAGGACGCAAGCAGCTCCT
CAAATTGTCTAGTCTCTATGCCTATTCCGAATTGTTTTCAGCACTTTATTCTAGGATTAGAAAAGTCAACCTGAATCTT
CCTGTTCCTTATGAACCACCTAGAAGAAAAGCGTCGTTAATGATGCATTAA
4169.3
ATGATGGAGTTTTTTCAACAGCTTCCTCATTTAGAGCCATATGGCAATCCTCAGTATTTTGTTTATGTGATTGCTGCAA
CCTTGCCCATCTTTATAGGTCTCTTTTTCAAGAAACGCTTTGCCTGGTATGAAGTGTTGGTAAGTCTCTTCTTTATTGT
CACCATGTTGGTGGGTGGAAAGACCAATCAACTAGCTGCCTTGGGTATTTACCTTTGCTGGGAAATATTGCTCCTGCTT
TTCTACAAGCATTATCGAAAAAGCAAGGATGGCAAGTGGGTCTTCTACTTAGTTAGTTTTCTGTCCCTACTTCCGATTA
TCTGTCAAGGTGCAACCAGCTATCAATGGAACGCAGTCTTTGCTTGGGTTCTTGGGAATTTCTTACCTGACCTTTCGTT
CGGTTGGAATTGTCATCGAGCTGAGAGATGGAGTGATTAAGGATTTTACCCTCTGGGAATTCCTCCGTTTCCTTCTCTT
CATGCCAACTTTCTCGAGTGGTCCAATCGATCGCTTTAAGCGATTTAATGAAAATTATCAGGCTATTCCTGAGCGAGAT
GAGTTGATGGATATGCTGGATGAATCTGTCCGCTATATCATGTGGGGCTTTTTGTATAAGTTTATCCTAGCTCATGTTT
TAGGAGAGACCTTACTACCTCCTCTGAAGAATTTAGCCTTGCAGTCAGGTGGCTTCTTTAATCTCTATGCCTTGGCAGT
TATGTATACTTTTGGTCTGGAACTCTTCTTTGACTTTGCAGGTTATTCTATGTTTTGCTTTGGCCATCTCAAACTTGAT
GGGAATCCGTAGCCCTATCAACTTTAACAAGCCTTTTTTATCAAGGGATTTAAAGGAGTTTTGGAATCGCTGGCATATG
AGTCTGTCCTTCTGGTTCCGTGACTTTGTCTTTATGCGAATGGTGATGGTGTTAACCAGAAAGAAAGTCTTTAAAAATC
GTAATGTAACCTCAAGCATGGCCTACATTGTAAATATGCTGATTATGGGATTTTGGCATGGTGTGACCTGGTACTATAT
CGCCTATGGACTCTTTCATGGACTAGGCTTGGTCATCAATGATGCCTGGGTTCGCAAGAAAAAAACGCTCAATAAGGAA
CGGAAAAAAGCAGGGAAGGCTGCCCTACCTGAGAATCGCTGGATTCAGTTGCTGGCATGGTGTCACTCCATGTTGTCAT
GTTGTCATTCTTAATCTTTTCTGGATTCTTGAATAATCTATGGTTTAAAAAATAA
4169.43
ATGCTTAAACGCTTATGGATGATCTTCGGACCGGTCTTGATCGCTGGTTTGTTGGTTTTTCTGCTCATTTTCTTTTATC
CTACTGAGATGCATCATAATCTAGGAGCTGAAAAGCGTTCAGCAGTGGCTACTACTATCGATAGTTTTAAGGAGCGAAG
TCAAAAGTCAGAGCACTATCTGATCCAAATGTGCGTTTTGTTCCCTTCTTTGGCTCTAGTGAATGGCTTCGTTTTGACG
GTGCTCATCCTGCGGTATTAGCTGAGAAATACAATCGTTCCTACCGTCCTTATCTTTTAGGACAGGGGGGAGCTGCATC
GCTTAACCAATATTTTGGAATGCAACAGATGTTACCACAGCTGGAGAATAAACAAGTTGTGTATGTTATCTCACCTCAG
TGGTTCAGTAAAAATGGCTATGATCCAGCAGCCTTCCAGCAGTATTTTAATGGAGACCAGTTGACTAGTTTTCTGAAAC
ATCAATCTGGGGATCAGGCTAGTCAATATGCAGCGACTCGCTTACTGCAACAGTTCCCAAACGTAGCTATGAAGGACCT
GGTTCAGAAGTTGGCAAGTAAAGAAGAATTGTCGACAGCAGACAATGAAATGATTGAATTATTGGCTCGTTTTAATGAA
CGCCAAGCTTCCTTTTTTGGTCAGTTTTCGGTTAGAGGCTATGTTAACTACGATAAGCATGTAGCTAAGTATTTAAAAA
TCTTGCCAGACCAGTTTTCTTATCAGGCAATAGAAGATGTTGTCAAGCAGATGCTGAAAAAAATACTTCCAATAATGAG
ATGGGAATGGAAAATTATTTCTATAATGAGCAGATCAAGAAGGATTTGAAGAAATTAAAGGATTCTCAGAAAAGCTTTA
CCTATCTCAAGTCGCCAGAGTATAATGACTTGCAGTTGGTTTTAACACAGTTTTCTAAATCTAAGGTAAACCCGATTTT
TATCATTCCACCTGTTAATAAAAAATGGATGAACTATGCTGGTCTACGAGAGGATATGTACCAACAAACGGTGCAGAAG
ATTCGCTACCAGTTAGAAAGTCAAGGTTTTACCAATATAGCAGATTTTTCTAAGGACGGCGGGAGCCTTTCTTTATGAA
GGACACCATTCACCTTGGTTGGTTGGGTTGGTTGGCTTTTGACAAGGCAGTTGATCCTTTCCTAATCCAATCCCACACC
AGCTCCGACTTACCATCTGAATGAGCGCTTTTTCAGCAAAGATTGGGCGACTTATGATGGAGATGTCAAAGAATTTCAA
TAG
4169.6
ATGGAGAAAAACCTCAAGGCTTTGAAACAAACAACAGACCAAGAAGGCCCAGCAATTGAACCTGAAAAGGCAGAGGATA
CCAAGACAGTCCAAATGGTTACTTCGAGGATGCAGCTGTCAAGGACCGCACCTTGAGTGACTATGCGGTAACTGGCAAT
CAGTTTATCCTTTCCTTGAAGACGGCACGTTTGACCAAGTCTTTGACTACAAGGCTAAGTTGACTGGTAAGATGACCCA
GGCTGAGTACAAGGCTTACTATACAAAAGGCTATCATACAGATGTGACTAAGATTAACATTACTGATAATACTATGGAA
TTTGTTCAAGGTGGACAAAGCAAGAAATACACTTACAAGTATGTCGGTAAGAAAATTTTGACTTACAAGAAAGGCAATC
GTGGCGTGCGTTTCCTCTTTGAAGCCACAGATGCTGACGCTGGACAATTCAAGTATGTTCAGTTTAGTGACCACAATGT
TGCCCCAGTTAAGGCAGAACATTTCCATATCTTCTTTGGAGGCACAAGCCAAGAAGCCCTCTTTGAAGAAATGGACAAC
TGGCCAACCTACTACCCAGATAACCTATCTGGCCAAGAAATCGCCCAAGAAATGTTGGCGCATTGA
4170.3.
ATGAAAGATGGTCATTTGCTAGCCCATCATATTCGTTTGTTGAATGGGCGGATTTTTCAAAAGTTACTGAGTCAAGATC
CTGAGGCTCTTTATAGGGGTGAACAGGGCAAGATTTTAGCGGTTTTATGGAATAGTGAAACTGGCTGCGCAACTGCGAC
AGATATCGCGCTTGCGACTGGACTTGCGAATAATACGCTGACGACTATGATAAAAAAGCTAGAGGAACAAAAGCTTGTA
ATTGTTAGTCCGTGTGGAAAAGACAAGCGTAAGAAGTATTTAGTTTTAACGGAGTTAGGCAAGTCCCAGAAAGAAGTGG
GGCATCGTGTCAGTCAGAAATTGGATACTATCTTTTACAAAGGATTTTCAGAGGAAGAAATTCACCAATTGAAGGTTCA
AGAAAGAATTGGCGAATCTGAAAGAGAAGGGAAATGAGGTTTAG
4170.4
ATGACTAATTTAATTGCAACTTTTCAGGATCGTTAGTGATTGGTTGACAGCTCTATCTCAACATTTGCAGTTGTCGCTT
TTGACCTTGTTACTAGCTATTTTGCTTGCGATTCCCTTGGCTGTTTTTCTTCGCTATCATGAGAAGCTGGCCGACTGGG
TCTTGCAGATTGCAGGTATTTTCCAGACCATCCCGTCTCTGGCCTTGTTGGGGCTCTTTATCCCTTTGATGGGAATTGG
GACCTTGCCGGCTTTGACAGCTCTAGTGATTTATGCGATTTTCCCTATTTTGCAAAATACTATCACTGGGCTGAAGGGA
ATTGATCCGAACCTGCAAGAGGCTGGGATTGCCTTTGGGATGACCAGATGGGAACGTCTCAAGAAATTTGAAATTCCAC
TCGCCATGCCTGTTATCATGTCTGGGATTCGGACGGCAGCTGTTTTGATTATCGGTACGGCAACCTTGGCGGCCTTGAT
TGGTGCAGGGGGACTAGGTTCCTTTATTCTTTTGGGAATTGACCGTAATAATGCCAGTTTGATTTTGATTGGGGCACTT
TCTTCTGCAGTGCTAGCCATTGCCTTTAACTTCCTACTAAAAGTGATGGAAAAAGCAAAATTACGGACGATTTTCTCAG
GTTTTGCCTTGGTGGCTTTATTACTGGGTCTGTCTTATAGTCCAGCTCTTTTGGTTCAAAAAGAGAAGGAAAACTTGGT
TATTGCTGGGAAAATAGGTCCAGAACCAGAAATTTTGGCCAATATGTATAAGTTGCTGATTGAAGAAAATACCAGCATG
ACTGCGACTGTTAAACCGAATTTTGGGAAGACAAGCTTCCTTTATGAAGCTCTGAAAAAAGGCGATATTGACATCTATC
CTGAATTTACTGGTACGGTGACTGAAAGTTTGCTTCAACCATCACCCAAGGTGAGTCATGAACCAGAACAGGTTTATCA
GGTGGCGCGTGATGGCATTGCTAAGCAGGATCATCTAGCCTATCTCAAACCCATGTCTTATCAAAACACCTATGCTGTA
GCTGTTCCGAAAAAGATTGCTCAAGAATATGGCTTGAAGACCATTTCAGACTTGAAAAAAGTGGAAGGGCAGTTGAAGG
CAGGTTTTACACTCGAGTTTTAACGACCGTGAAGATGGAAATAAGGGCTTGCAATCAATGTATGGTCTCAATCTCAATG
TAGCGACCATTGAGCCAGCCCTTCGCTATCAGGCTATTCAGTCAGGGGATATTCAAATCACGGATGCCTATTCGACTGA
TGCGGAATTGGAGCGTTATGATTTACAGGTCTTGGAAGATGACAAGCAACTCTTCCCACCTTATCAAGGGGCTCCACTC
ATGAAAGAAGCTCTTCTCAAGAAACACCCAGAGTTGGAAAGAGTTCTTAATACATTGGCTGGTAAGATTACAGAAAGCC
AGATGAGCCAGCTCAACTACCAAGTCGGTGTTGAAGGCAAGTCAGCAAAGCAAGTAGCCAAGGAGTTTCTCCAAGAACA
AGGTTTGTTGAAGAAATGA
4170.5
ATGATGCATACTTATTTGCAAAAGAAAATTGAAAATATCAAAACAACCCTAGGTGAAATGTCAGGTGGTTACCGTCGTA
TGGTTGCGGCTATGGCTGATTTAGGATTTTCAGGAACTATGAAGGCTATCTGGGATGACCTCTTTGCCCATCGTAGTTT
TGCCCAGTGGATTTATTTGCTGGTTTTAGGAAGTTTTCCTCTCTGGCTGGAGTTGGTTTACGAACATCGTATTGTTGAC
TGGATTGGGATGATTTGTAGCTTGACAGGGATTATCTGTGTAATCTTTGTATCGGAAGGTCGAGCAAGTAATTATCTTT
TTGGCTTGATTAACTCTGTTATTTACCTTATTTTGGCCCTACAGAAAGGCTTTTATGGTGAGGTGCTGACGACACTTTA
CTTCACAGTCATGCAGCCAATTGGACTCTAGTTTGGATTTATCAGGCACAGTTTAAGAAGGAAAAGCAGGAGTTTGTCG
CGCGTAAACTGGACGGCAAGGGCTGGACAAAGTATCTTTCCATTAGTGTGCTTTGGTGGTTGGCCTTTGGCTTCATTTA
TCAGTCTATTGGTGCCAATCGTCCCTATCGTGATTCAATCACAGATGCAACCAATGGGGTAGGGCAAATCCCATGACAG
CTGTTTACCGTGAACAGTGGATATTCTGGGCGGCTACCAATGTCTTTTCAATCTATCTCTGGTGGGGAGAAAGCCTGCA
AATTCAAGGGAAATATCTAATTTATCTCATTAACAGTCTAGTTGGTTGGTATCAATGGAGCAAGGCAGCTAAGCAGAAT
ACTGATTTACTTAACTAG
4170.6
ATGAGAAATATGAAGGCAAAATATGCTGTTTGGGTGGCTTTTTTCTTAAATTTGACTTATGCCATTGTTGAGTTTATTG
CAGGTGGAGTATTTGGTCTAGCGCTGTTCTTGCTGACTCTGTGCATGACTTGGGAGATGCGATTGCAATTGGAATATCA
GCTTTTCTAGAAACAATCTCCAATCGTGAAGAAGACAATCAGTACACCTTGGGCTATAAGCGGTTTAGCCTGCTAGGAG
CCTTGGTAACAGCTGTGATTCTCGTAACGGGCTCTGTTCTAGTCATTTTGGAAAATGTCACGAAGATTTTGCATCCGCA
ACCAGTCAATGATGAGGGGATTCTCTGGTTAGGAATTATTGCGATTACTATCAATCTGTTAGCGAGTCTGGTGGTTGGT
AAGGGAAAGACAAAGAATGAGTCTATTCTGAGTCTGCATTTTCTGGAAGATACGCTAGGGTGGGTAGCTGTTATCCTGA
TGGCGATTGTTCTTCGATTTACGGACTGGTATATCCTAGATCCTCTTTTGTCCCTTGTCATTTCTTTCTTTATTCTTTC
AAAAGCCCTTCCACGTTTTTGGTCTACACTCAAGATTTTCTTGGATGCTGTGCCAGAAGGTCTTGATATCAAGCAAGTA
AAGAGTGGCCTGGAGCGATTGGACAATGTGGCCAGCCTTAATCAGCTTAATCTCTGGACTATGGATGCTGGAAAAAAAT
GCCATTGTCCATGTTTGTCTAAAAGAAATGGAACATATGGAAACTTGTAAAGAGTCTATTCGAATTTTCCTAAAAGATT
GTGGTTTTCAAAATATTACCATTGAAATTGATGCTGACCTAGAAACTCACCAAACCCATAAGCGAAAGGTGTGTGACTT
GGAACGGAGTTATGAGCATCAACATTAG
4170.8
ATGATTGAATACAAAAATGTAGCACTGCGCTACACAGAAAAGGATGTCTTGAGAGATGTCAACTTACAGATTGAGGATG
GGGAATTTATGGTTTTAGTAGGGCCTTCTGGGTCAGGTAAGACGACCATGCTCAAGATGATTAACCGTCTTTTGGAACC
AACTGATGGAATATTTATATGGATGGGAAGCGCATCAAAGACTATGATGAGCGTGAACTTCGTCTTTCTACTGGTTATG
TTACAGGCTATTGCTCTTTTCCAAATCTAACAGTTGCGGAAAATATTGCTCTCATTCCTGAAATGAAGGGGTGGAGCAA
GGAAGAAATTACGAAGAAAACAGAAGAGCTTTTGGCTAAGGTTGGTTTACCAGTAGCCGAGTATGGGCATCGCTTACCT
AGTGAATTATCTGGTGGAGAACAGCAACGGGTCGGTATTGTCCGAGCTATGATTGGTCAGCCCAAGATTTTCCTCATGG
ATGAACCCTTTTCGGCCTTGGATGCTATTTCGAGAAAACAGTTGCAGGTTCTGACAAAAGAATTGCATAAAGAGTTGGG
ATGACAACGATTTTTGTAACCCATGATACGGATGAAGCCTTGAAGTTGGCGGACCGTATTGCTGTCTTGCAGGATGGAG
AAATTCGCCAGGTAGCGAATCCCGAGACAATTTTAAAAGCGCCTGCAACAGACTTTGTAGCAGACTTGTTTGGAGGTAG
TGTTCATGACTAA
4171.1
ATGTCAGCAGTTGCTATTTCAGCTATGACCAAGGTTATGCAAGAAACCCACGGAAATCCTTCTAGTATTCATGGTCATG
GTCGTCAAGCTGGCAAACTCTTGCGAGAAGCCCGTCAGGAACTAGCCCAGTTACTAAGGACAAAACCTCAACATATCTT
TTTCACTTCTGGTGGGACTGAAGGCAATAATACTACCATCATTGGCTACTGTCTTCGTCACCAAGAACAAGGAAAACAT
ATCATCACAACTGCCATCGAGCACCATGCTGTCCTTGAAACAATTGATTACTTGGTTCAACACTTTGGGTTTGAAGCAA
CCATTATCCAGCCAGAAAATCAAGAAATCACAGCCCAGCAAATTCAAAAGGCTTTACGTGACGATACGATTTTGGTTTC
TACCATGTTTGTCAATAATGAGACAGGAAACCTACTGCCCATCGCTGAAATTGGCCAAATACTCAAGCAACACCCTGCT
GCCTATCATGTTGATGCAGTTCAGGCTATTGGTAAAATCCCAATTCATTCAGAAGAATTGGGCATTGATTCTCACTGCT
TCTGCCCACAAATTCCATGGTCCTAAGGGAATCGGTTTTCTCTACGCATCTAGCATGGACTTTGATTCCTATCTACATG
GCGGAGACCAGGAACAGAAAAAACGTGCAGGAACTGAAAATCTGCCTGCCATTGTAGGCATGGTTGCAGCCCTAAAAGA
AGACCTAGAAAAACAAGAAGAACATTTTCAACATGTACAAAATCTAGAAACTGCCTTTCTGGCAGAGCTGGAGGGCATT
CAGTATTACCTGAATAGAGGAAAACATCATCTCCCTTATGTTCTCAATATTGGATTTCCTGGTCAGAAAAATGACCTCT
TACTCCTTCGGCTAGATTTAGCTGGAATTTCAATCTCTACTGGCTCAGCCTGTACTGCAGGCGTTGTCCAATCCAGCCA
TGTTCTTGAAGCCATGTATGGCGCAAATTCAGAACGCTTGAAGGAATCCCTTCGCATCAGTTTGTCGCCACAAAATACC
GTTGAAGACCTACAAACCCTCGCAAAAACCTTAAAAGAAATTATCGGAGGTTAG
4172.1
ATGTTATTCAAATTATCTAAGGAAAAAATAGAGCTAGGCTTATCTCGTTTATCGCCAGCCCGTCGTATTTTTTTGAGTT
TTGCCTTGGTCATTTTACTAGGCTCTCTTCTTTTGAGCTTGCCCTTTGTCCAAGTTGAAAGCTCACGAGCGACTTATTT
TGATCATCTTTTCACTGCTGTCTCTGCAGTCTGTGTGACGGGTCTCTCAACCCTTCCAGTAGCTCACACCTATAATATC
TGGGGTCAAATAATCTGTTTGCTCTTGATTCAGATCGGTGGTCTAGGGCTCATGACCTTTATTGGGGTTTTCTATATCC
AGAGCAAGCAAAAGCTTAGTCTTCGTAGCCGTGCAACTATTCAGGATAGTTTTAGTTATGGAGAAACTCGATCTTTGAG
AAAGTTTGTCTATTCTATTTTTCTCACGACCTTTTTGGTTGAGAGCTTGGGAGCTATTTTGCTTAGTTTTCGCCTTATT
CCTCAACTTGGCTGGGGACGTGGTCTTTTTAGTTCCATTTTTCTAGCGATCTCAGCCTTCTGTAATGCCGGTTTTGATA
ATTTAGGGAGCACCAGTTTATTTGCTTTTCAGACCGATTTACTGGTCAATCTGGTGATTGCAGGCTTGATTATTACAGG
CGGCCTTGGTTTTATGGTCTGGTTTGATTTGGCTGGTCATGTAGGAAGAAAGAAAAAAGGACGTCTGCACTTTCATACG
AAGCTTGTACTATTATTGACTATAGGTTTGTTGTTATTTGGAACAGCAACTACTCTCTTTCTTGAGTGGAACAATGCTG
GAACGATTGGCAATCTCCCTGTTGCCGATAAGGTTTTAGTTAGCTTTTTTCAAACAGTGACGATGCGAACAGCTGGCTT
TTCTACGATAGATTATACTCAGGCTCATCCTGTGACTCTTTTGATTTATATCTTACAGATGTTTCTAGGTGGGGCACCT
GGAGGAACAGCTGGGGGACTCAAGATTACGACATTTTTTGTCCTCTTGGTCTTTGCACGAAGTGAGCTTCTAGGCTTGC
CTCATGCCAATGTTGCGAGACGAACGATCGCGCCGCGAACGGTTCAAAAATCCTTTAGTGTCTTTATTATCTTTTTGAT
GAGCTTCTTGATAGGATTGATTCTGCTAGGGATAACAGCCAAAGGCAATCCTCCCTTTATCCACCTCGTATTTGAAACC
ATTTCAGCTCTTAGTACAGTTGGTGTAACGGCAAATCTGACTCCTGACCTGGGAAATTGGCTCTCAGGTTATCATGCCA
CTTATGTTTATGGGACGAATTGGTCCCTTGACCTTGTTTGTTAGCTTGGCAGATTACCATCCAGAAAAGAAAGATATGA
TTCACTATATGAAAGCAGATATTAGTATTGGTTAA
4172.2
ATGTCAGATCCTACGATTGGAATTTTGGGCTTGGGAATTTTTGGGAGCAGTGTCCTAGCTGCCCTAGCCAAGCAGGATA
TGAATATTATCGCTATTGATGACCACGCAGAGCGCATCAATCAGTTTGAGCCAGTTTTGGCGCGTGGAGTGATTGGTGA
CATCACAGATGAAGAATTATTGAGATCAGCAGGGATTGATACCTGCGATACCGTTGTAGTCGCGACAGGTGAAAATCTG
GAGTCGAGTGTGCTGCGGTTATGCACTGTAAGAGTTTGGGGGTACCGACTGTTATTGCTAAGGTCAAAAGTCAGACCGC
TAAGAAAGTGCTAGAAAAGATTGGAGCTGACTCGGTTATCTCGCCAGAGTATGAAATGGGGCAGTCTCTAGCACAGACC
ATTCTTTCCATAATAGTGTTGATGTCTTTCAGTTGGATAAAAATGTGTCTATCGTGGAGATGAAAATTCCTCAGTCTTG
GGCAGGTCAAAGTCTGAGTAAATTAGACCTCCGTGGCAAATACAATCTGAATATTTTGGGTTTCCGAGAGCAGGAAAAT
TCCCCATTGGATGTTGAATTTGGACCAGATGACCTCTTGAAAGCAGATACCTATATTTTGGCAGTCATCAACAACCAGT
ATTTGGATACCCTAGTAGCATTGAATTCGTAA
4172.3
ATGAAGTTATTGTCTATCGCAATTTCTAGCTATAATGCAGCAGCCTATCTTCATTACTGTGTGGAGTCGCTAGTGATTG
GTGGTGAGCAAGTTGGGATTTTGATTATCAATGACGGGTCTCAGGATCAGACTCAGGAAATCGCTGAGTGTTTAGCTAG
CAAGTATCCTAATATCGTTAGAGCCATCTATCAGGAAAATAAATGCCATGGCGGTGCGGTCAATCGTGGCTTGGTAGAG
GCTCTGGGCGCTATTTTAAAGTAGTTGACAGTGATGACTGGGTGGATCCTCGTGCCTACTTGAAAATTCTTGAAACCTT
GCAGGAACTTGAGAGCAAAGGTCAAGAGGTGGATGTCTTTGTGACCAATTTTGTCTATGAAAAGGAAGGGCAGTCTCGT
AAGAAGAGTATGAGTTACGATTCAGTCTTGCCTGTTCGGCAGATTTTTGGCTGGGACCAGGTCGGAAATTTCTCCAAAG
GCCAGTATACCATGATGCACTCGCTGATTTATCGGACAGATTTGTTGCGTGCTAGCCAGTTCTAA
4172.4
ATGAAATTCAATCCAATCAAGATATACTCGTTGGTCTATTCGCCGTCTCAGTGTCGGTGTTGCCTCAGTTGTTGTGGCT
AGTGGCTCTGTCCTAGTTGGTCAGCCAAGTTCTGTACGTGCCGATGGGCTCAATCCAACCCCAGGTCAAGTCTTACCTG
AAGAGACATCGGGAACGAAAGAGGGTGACTATCAGAAAAACCAGGAGACACCGTTCTCACTCAAGCGAAACCTGAGGGC
GTTACTGGAAATACGAATTCACTTCCGACACCTACAGAAAGAACTGAAGTGAGCGAGGAAACAAGCCCTTCTAGTCTGG
ATACACTTTTTGAAAAAGATGAAGAAGCTCAAAAAAATCCAGAGCTAACAGATGTCTTAAAAGAAACTGTAGATACAGC
TGATGTGGATGGGACACAAGCAAGTCCAGCAGAAACTACTCCTGAACAAGTAAAAGGTGGAGTGAAAGAAAATACAAAA
GACAGCATCGATGTTCCTGCTGCTTATCTTGAAAAAGCTGAAGGGAAAGGTCCTTTCACTGCCGGTGTAAACCAAGTAA
TTCCTTATGAACTATTCGCTGGTGATGGTATGTTAACTCGTCTATTACTAAAAGCTTCGGATAATGCTCCTGGTCTGAC
AATGGTACTGCTAAAATCCTGCTTTACCTCCTCTTGAAGGATTAACAAAAGGGAAATACTCTATGAAGTAGACTTAAAT
GGCAATACTGTTGGTAAACAAGGTCAAGCTTTAATTGATCAACTTCGCGCTAATGGTACTCAAACTTATAAAGCTACTG
TTAAAGTTTACGGAAATAAAGACGGTAAAGCTGACTTGACTAATCTAGTTGCTACTAAAAATGTAGACATCAACATCAA
TGGATTAGTTGCTAAAGAAACAGTTCAAAAAGCCGTTGCAGACAACGTTAAAGACAGTATCGATGTTCCAGCAGCCTAC
CTAGAAAAAGCCAAGGGTGAAGGTCCATTCACAGCAGGTGTCAACCATGTGATTCCATACGAACTCTTCGCAGGTGATG
GCATGTTGACTCGTCTCTTGCTCAAGGCATCTGACAAGGCACCATGGTCAGATAACGGCGACGCTAAAAACCCAGCCCT
ATCTCCACTAGGCGAAAACGTGAAGACCAAAGGTCAATACTTCTATCAAGTAGCCTTGGACGGAAATGTAGCTGGCAAA
GAAAAACAAGCGCTCATTGACCAGTTCCGAGCAAATGGTACTCAAACTTACAGCGCTACAGTCAATGTCTATGGTAACA
AAGACGGTAAACCAGACTTGGACAACATCGTAGCAACTAAAAAAGTCACTATTAACATAAACGGTTTAATTTCTAAAGA
AACAGTTCAAAAAGCCGTTGCAGACAACGTTAAGACAGTATCGATGTTCCAGCAGCCTACCTAGAAAAAGCCAAGGGTG
AAGGTCCATTCACAGCAGGTGTCAACCATGTGATTCCATACGAACTCTTCGCAGGTGATGGTATGTTGACTCGTCTCTT
GCTCAAGGCATCTGACAAGGCACCATGGTCAGATAACGGTGACGCTAAAAACCCAGCCCTATCTCCACTAGGTGAAAAC
GTGAAGACCAAAGGTCAATACTTCTATCAATTAGCCTTGGACGGAAATGTAGCTGGCAAAGAAAAACAAGCGCTCATTG
ACCAGTTCCGAGCAAACGGTACTCAAACTACAGCGCTACAGTCAATGTCTATGGTAACAAAGACGGTAAACCAGACTTG
GACAACATCGTAGCAACTAAAAAAGTCACTATTAACATAAACGGTTTAATTTCTAAAGAAACAGTTCAAAAAGCCGTTG
CAGACAACGTTAAGACAGTATCGATGTTCCAGCAGCCTACCTAG
4172.5
ATGAAACTAAAAAGTTATATTTTGGTTGGATATATTATTTCAACCCTCTTAACCATTTTGGTTGTTTTTTGGGCTGTTC
AAAAAATGCTGATTGCGAAAGGCGAGATTTACTTTTTGCTTGGGATGACCATCGTTGCCAGCCTTGTCGGTGCTGGGAT
TAGTCTCTTTCTCCTATTGCCAGTCTTTACGTCGTTGGGCAAACTCAAGGAGCATGCCAAGCGGGTAGCGGCCAAGGAT
TTTCCTTCAAATTTGGAGGTTCAAGGTCCTGTAGAATTTCAGCAATTAGGGCAAACTTTTAATGAGATGTCCCATGATT
TGCAGGTAAGCTTTGATTCCTTGGAAGAAAGCGAACGAGAAAAGGGCTTGATGATTGCCCAGTTGTCGCATGATATTAA
GACTCCTATCACTTCGATCCAAGCGACGGTAGAAGGGATTTTGGATGGGATTATCAAGGAGTCGGAGCAAGCTCATTAT
CTAGCAACCATTGGACGCCAGACGGAGAGGCTCAATAAACTGGTTGAGGAGTTGAATTTTTTGACCCTAAACACAGCTA
GAAATCAGGTGGAAACTACCAGTAAAGACAGTATTTTTCTGGACAAGCTCTTAATTGAGTGCATGAGTGAATTTCAGTT
TTTGATTGAGCAGGAGAGAAGAGATGTCCACTTGCAGGTAATCCCAGAGTCTGCCCGGATTGAGGGAGATTATGCTAAG
CTTTCTCGTATCTTGGTGAATCTGGTCGATAACGCTTTTAAATATTCTGCTCCAGGAACCAAGCTGGAAGTGGTGGCTA
AGCTGGAGAAGGACCAGCTTTCAATCAGTGTGACCGATGAAGGGCAGGGTATTGCCCCAGAGGATTTGGAAAATATTTT
CAAACGCCTTTATCGTGTCGAAACTTCGCGTAACATGAAGACAGGTGGTCATGGATTAGGACTTGCGATTGCGCGTGAA
TTGGCCCATCAATTGGGTGGGGAAATCACAGTCAGCAGCCAGTACGGTCTAGGAAGTACCTTTACCCTCGTTCTCAACC
TCTCTGGTAGTGAAAATAAAGCCTAA
4172.6
ATGTTTGGTCAAACGGCTCAACATGGTCTTACGAATAGCCTGAAAGACTTCTGGATTTTTCTGCTGAATATAGGTCCAC
AATTGGCGTTTTTTTGCCAGATGCTCCGCTGTTCCAGATCGGTTGAGCAGGGTACTGGAAATCACCGTCGTGAGTTCAA
TATGATTCAGCAGATATTCTCGCATTTTGGGATGACTCACTTGGGACAAATCAAGTTGGTCTATCAAGAGTCGATTGAC
CTTGAGTTGCTGGTCAATGCACTTAATCATCACTTGCTCATTGACAGACTGGTCCTCACGCCCAATCAAATAACGATAG
AAATCGACAGGCAGATAGTACATGGTCTTGACCTGCTGAAGGGGCGTAAAGACAAAGAGATTATCGACATAAAAAGTAT
GTTCAGGCAGTTAGAACTGGCTAGCACGCAACAAATCTGTCCGATAAATCAGCGAGTGCATCATGGTATACTGGCCTTT
GGAGAAATTTCCGACCTGGTCCCAGCCAAAAATCTGCCGAACAGGCAAGACTGA
4174.1
ATGGAACATTTAGCAACTTATTTTTCAACCTATGGAGGAGCTTTCTTCGCTGCATTGGGAATTGTATTGGCGGTTGGAT
TAAGCGGTATGGGGTCTGCTTATGGAGTTGGTAAGGCTGGGCAATCTGCCGCAGCTTTACTGAAAGAACAGCCTGAAAA
GTTTGCCTCAGCTTTGATATTGCAATTATTGCCCGGAACACAAGGATTATATGGTTTTGTTATTGGAATTTTAATTTGG
TTGCAATTAACTCCAGAACTTCCTTTAGAAAAAGGCGTTGCTTATTTCTTTGTAGCTCTTCCAATTGCTATTGTAGGAT
ACTTTTCAGCTAAGCATCAAGGAAATGTAGCAGTAGCGGGAATGCAAATCTTGGCAAAAGACCAAAAGAATTCATGAAG
GGAGCAATTTTAGCTGCCATGGTAGAAACCTATGCAATTCTTGCTTTTGTCGTATCATTCATTTTGACCCTTCGTGTAT
AA
4175.2
ATGTTAAAATCAGAAAAACAATCACGTTATCAAATGTTAAATGAAGAATTGTCCTTCCTATTGGAAGGCGAAACCAATG
TTTTGGCTAATCTCCAACGCCAGTGCTCTCATAAAATCACGTTTTCCTAATACCGTATTTGCAGGCTTTTATTTGTTCG
ATGGAAAGGAATTGGTTTTAGGCCCCTTCCAAGGAGGTGTTTCCTGCATCCGTATTGCACTAGGCAAGGGTGTTTGTGG
TGAGGCAGCTCACTTTCAGGAAACTGTTATTGTTGGAGATGTGACGACCTATCTCAACTATATTTCTTGTGATAGTCTA
GCTAAAAGTGAAATTGTGGTGCCGATGATGAAGAATGGTCAGTTACTTGGAGTTCTGGATCTGGATTCTCAGAGATTGA
GGATTACGATGCTATGGATCGAGATTATTTGGAACAATTTGTCGCTATTTTGCTTGAAAAGACAGCATGGGACTTTACG
ATGTTTGAGGAAAAATCTTAA
4175.3
ATGTCAGTATTAGAGATCAAAGATCTTCACGTTGAGATTGAAGGAAAAGAAATTTTAAAAGGGGTTAACCTGACCCTGA
AAACAGGAGAAATTGCCGCTATCATGGGACCAAATGGTACAGGTAAATCGACTCTTTCTGCCGCTATCATGGGAAATCC
AAACTATGAAGTAACTAAAGGTGAAGTTTTGTTTGATGGCGTAAACATCCTTGAGTTGGAAGTGGATGAGCGTGCGCGT
ATGGGACTTTTCCTTGCTATGCAATACCCATCAGAAATCCCTGGAATTACCAATGCTGAGTTTCTTCGTGCCGCTATGA
ATGCGGGTAAAGAAGATGATGAGAAGATTTCAGTTCGTGAGTTTATTACTAAGCTAGATGAAAAAATGGAATTGCTCAA
CATGAAAGAAGAAATGGCAGAGCGTTACCTCAACGAAGGCTTCTCTGGTGGTGAGAAAAAACGCAATGAAATTCTTCAA
CTTTTGATGTTGGAGCCAACATTTGCTCTTTTGGACGAGATTGACTCAGGTCTTGATATTGACGCTCTTAAAGTTGTGT
CTAAAGGTGTCAATGCCATGCGTGGTGAAGGTTTTGGTGCTATGATCATCACTCACTACCAACGTCTTTTGAACTATAT
CACACCTGATGTGGTACACGTGATGATGGAAGGTCGTGTTGTCCTTTCTGGTGGTCCAGAATTGGCTGCGCGTTTGGAA
CGTGAAGGATACGCAAAATTAGCTGAAGAACTTGGCTACGACTACAAGGAAGAATTGTAA
4174.4
ATGCCCTACAAAAGACAAAGGAGTTTTTCAATGGCACTTTCTAAACTAGATAGCCTTTATATGGCAGTGGTAGCAGACC
ATTCGAAAAATCCACATCACCAAGGGAAGTTAGAAGATGCTGAGCAAATCAGTCTCAACAATCCGACTTGTGGGGATGT
CATCAACCTCTCTGTCAAGTTTGATGCAGAGGACCGTTTGGAAGATATTGCTTTTCTAAATTCAGGATGCACGATTTCA
ACTGCTTCTGCTAGTATGATGACAGATGCCGTTTTAGGAAAAACCAAACAAGAAATTTTAGAACTGGCGACTATTTTTT
CTGAAATGGTTCAAGGGCAAAAAGATGAGCGTCAAGACCAACTTGGAGACGCGGCATTCTTGTCAGGTGTTGCCAAATT
CCCTCAAAGAATCAAGTGTGCAACCCTAGCTTGGAATGCCCTTAAGAAAACAATTGAAAATCAAGAAAAACAGTAA
4175.5
ATGAAAATTCAAGACCTATTGAGAAAAGATGTCATGTTGCTAGATTTTGCAGGCAACTGAAAAAACAGCTGTCATCGAC
GAGATGATTAAAAATTTGACAGACCACGGTTATGTAACAGATTTTGAAACATTTAAAGAAGGAATTTTGGCGCGTGAAG
CTTTGACTTCTACTGGTTTGGGTGATGGAATCGCAATGCCTCACAGCAAAAACGCTGCTGTCAAAGAAGCGACAGTTCT
ATTTGCTAAGTCAAATAAGGGTGTTGACTACGAGAGCTTGGATGGACAAGCAACTGACCTCTTCTTCATGATTGCAGCT
CCAGAAGGTGCCAATGATACTCACTTGGCAGCCTTGGCAGAATTGTCTCAATACTTGATGAAAGACGGTTTTTGCAGAC
AAACTTCGTCAAGCAACATCTGCAGACCAAGTTATCGAACTTTTTGACCAAGCTTCAGAAAAAACTGAGGAACTTGTTC
AAGCACCTGCTAATGACTCTGGTGACTTTATCGTAGCTGTTACAGCTTGTACAACAGGTATTGCCCACACTTACATGGC
CCAAGAAGCCCTTCAAAAAGTAGCTGCTGAAATGGGGGTTGGTATCAAGGTCGAAACCAACGGTGCTAGCGGTGTTGGA
AATCAACTAACTGCAGAAGATATCCGTAAGGCTAAAGCTATTATCATTGCAGCAGACAAGGCCGTTGAAATGGATCGAT
TTGATGGAAAACCATTGATCAATCGTCCAGTTGCTGACGGTATCCGTAAGACAGAAGAGCTAATTAACTTGGCTCTTTC
AGGAGATACTGAAGTCTACCGTGCCGCTAATGGTGCCAAAGCTGCAACAGCCTCTAACGAAAAACAAAGCCTTGGTGGT
GCCTTGTACAAACACTTGATGAGTGGTGTATCTCAAATGTTACCATTCGTTATCGGTGGTGGTATCATGATTGCCCTTG
CCTTCTTGATTGACGGTGCTTTGGGTGTTCCAAATGAAAACCTTGGCAATCTTGGTTCTTACCATGAGTTAGCTTCTAT
GTTCATGAAAATTGGTGGAGCTGCCTTTGGTTTGATGCTTCCAGTCTTTGCGGGTTATGTTGCCTACTCTATTGCTGAA
AAACCGGGTTTGGTAGCAGGTTTCGTGGCTGGTGCTATTGCCAAAGAAGCTTTTGCCTTTGGTAAAATTCCTTATGCCG
CAGGTGGTGAAGCAACTTCAACTCTTGCAGGTGTCTCATCTGGTTTCCTAGGTGCCCTTGTGGTGGATTTATCGCAGGT
GCCTTGGTTCTTGCCATCAAGAAATACGTTAAAGTTCCTCGTTCACTCGAAGGTGCTAAATCAATCCTTCTATTGCCAC
TTCTTGGAACAATCTTGACAGGATTTGTTATGCTAGCTGTGAATATCCCAATGGCGCAATCAACACTGCTATGAATGAC
TTCCTAGGCGGTCTTGGAGGAGGTTCAGCTGTCCTTCTTGGTATCGTCCTTGGTGGAATGATGGCTGTTGACATGGGTG
GACCAGTTAATAAAGCAGCTTATGTCTTTGGTACAGGTACGCTTGCAGCAACTGTTTCTTCAGGTGGTTCTGTAGCCAT
GGCAGCAGTTATGGCTGGAGGAATGGTGCCACCACTTGCAATCTTTGTCGCAACTCTTCTTTTCAAAGATAAATTTACT
AAGCAAGAACGTAACTCTGGTTTGACAAACATCATCATGGGCTTGTCATTTATCACTGAGGGAGCGATTCCATTTGGTG
CCGCTGACCCAGCTCGTGCGATTCCAAGCTTCATCCTTGGTTCAGCAGTAGCAGGTGGACTCGTTGGTCTTACTGGTAT
CAAACTCATGGCGCCACACGCAGGAATCTCGTTATCGCCCTTACTTCAAATGCTCTCCTTTACCTCGTTTCTGTCTTGG
TAGGAGCAATCGTAAGTGGTGTGGTTTATGGTTACCTACGCAAACCACAAGCATAA
4175.6
ATGGCAAACAAGAATACAAGTACAACAAGACGGAGACCGTCTAAAGCAGAACTGGAAAGAAAAGAAGCGATTCAACGAA
TGTTGATTTCGTTAGGAATTGCGATTTTATTGATTTTCGCAGCCTTCAAATTAGGGGCTGCAGGTATAACCCTTTATAA
TTTAATTCGCTTGCTAGTGGGTAGCCTAGCTTATCTGGCGATATTCGGCCTATTAATCTATCTCTTCTTTTTCAAGTGG
ATACGAAAACAGGAAGGACTCTTATCTGGCTTTTTTCACCATATTTGCTGGCTTACTCTTGATTTTTGAGGCCTACTTG
GTTTGGAAATATGGTTTGGACAAGTCCGTTCTAAAAGGGACCATGGCTCAGGTTGTGACAGATCTGACTGGTTTTCGAA
CGACTAGCTTTGCTGGAGGGGGCTTGATCGGGGTCGCTCTTATATTCCAACAGCCTTTCTCTTTTCAAATATCGGAACT
TACTATTGGTTCTATCTTGATTTTAGTGGGTTCTCTCCTAGTCAGCCCTTGGTCTGTTTACGATATTGCTGAATTTTTC
AGTAGAGGCTTTGCCAAATGGTGGGAAGGGCACGAGCGTCGAAAAGAGGAACGCTTTGTCAAACAAGAAGAAAAAGCTC
GCCAAAAGGCTGAGAAAGAGGCTAGATTAGAACAAGAAGAGACTGAAAAAGCCTACTCGATTTGCCTCCTGTTGATATG
GAAACGGGTGAAATTCTGACAGAGGAAGCTGTTCAAAATCTTCCACCTATTCCAGAAGAAAAGTGGGTGGAACCAGAAA
TCATCCTGCCTCAAGCTGAACTTAAATTCCCTGAACAGGAAGATGACTCAGATGACGAAGATGTTCAGGTCGATTTTTC
AGCCAAAGAAGCCCTTGAATACAAACTTCCAAGCTTACAACTCTTTGCACCAGATAAACCAAAAGATCAGTCTAAAGAG
AAGAAAATTGTCAGAGAAAATATCAAAATCTTAGAAGCAACCTTTGCTAGCTTTGGTATTAAGGTAACAGTTGAACGGG
CCGAAATTGGGCCATCAGTGACCAAGTATGAAGTCAAGCCGGCTGTTGGTGTAAGGGTCAACCGCATTTCCAATCTATC
AGATGACCTCGCTCTAGCCTTGGCTGCCAAAGATGTCCGGATTGAAGCACCAATCCCTGGGAAATCCCTAATCGGAATT
GAAGTGCCCAACTCCGATATTGCCACTGTATCTTTCCGAGAACTATGGGAACAATCGCAAACGAAAGCAGAAAATTTCT
TGGAAATTCCTTTAGGGAAGGCTGTTAATGGAACCGCAAGAGCTTTTGACCTTTCTAAAATGCCCCACTTGCTAGTTGC
AGGTTCAACGGGTTCAGGGAAGTCAGTAGCAGTTAACGGCATTATTGCTAGCATTCTCATGAAGGCGAGACCAGATCAA
GTTAAATTTATGATGGTCGATCCCAAGATGGTTGAGTTATCTGTTTACAATGATATTCCCCACCTCTTGATTCCAGTCG
TGACCAATCCACGCAAAGCCAGCAAGGCTCTGCAAAAGGTTGTGGATGAAATGGAAAACCGTTATGAACTCTTTGCCAA
GGTGGGAGTTCGGAATATTGCAGGTTTTAATGCCAAGGTAGAAGAGTTCAATTCCCAGTCTGAGTACAAGCAAATTCCG
CTACCATTCATTGTCGTGATTGTGGATGAGTTGGCTGACCTCATGATGGTGGCCAGCAAGGAAGTGGAAGATGCTATCA
TCCGTCTGGGCAGAAGGCGCGTGCTGCAGGTATCCACATGATTCTTGCAACTCAGCGTCCATCTGTTGATGTCATCTCT
GGTTGATTAAGGCCAATGTTCCATCTCGTGTAGCATTTGCGGTTTCATCAGGAACAGACTCCCGTACGATTTTGGATGA
AAATGGAGCAGAAAAACTTCTTGGTCGAGGAGACATGCTCTTTAAACCGATTGATGAAAATCATCCAGTTCGTCTCCAA
GGCTCCTTTATCTCGGATGACGATGTTGAGCGCATTGTGAACTTCATCAAGACTCAGGCAGATGCAGACTACGATGAGA
GTTTTGATCCAGGTGAGGTTTCTGAAAATGAAGGAGAATTTTCGGATGGAGATGCTGGTGGTGATCCGCTTTTTGAAGA
AGCTAAGTCTTTGGTTATCGAAACACAGAAAGCCAGTGCGTCTATGATTCAGCGTCGTTTATCAGTTGGATTTAACCGT
GCGACCCGTCTCATGGAAGAACTGGAGATAGCAGGTGTCATCGGTCCAGCTGAAGGTACCAAACCTCGAAAAGTGTTAC
AACAATAA
4176.1
ATGAGTTATTTTAAAAAATATAAATTCGATAAATCCCAGTTCAAACTTGGTATGCGAACCTTTAAAACAGGTATTGCTG
TTTTTCTAGTTCTCTTGATTTTTGGCTTTTTTGGCTGGAAAGGTCTTCAAATTGGTGCTTTGACAGCCGTTTTTAGCCT
GAGGGAGAGTTTTGATGAGAGTGTTCATTTTGGGACTTCGCGTATTCTAGGAAATAGTATCGGTGGACTCTATGCCTTG
GTCTTCTTCTTATTAAATACCTTTTTCCACGAAGCCTTTTGGGTGACCTTGGTAGTTGTTCCAATCTGCACCATGTTAA
CCATTATGACAAATGTAGCCATGAATAACAAAGCAGGGGTTATTGGTGGTGTAGCAGCTATGTAATCATTACCCTATCA
ATTCCAAGTGGTGAGACAATTTTGTACGTGTTTGTGCGTGTATTAGAAACGTTTATGGGAGTTTTTGTCGCAATTATCG
TAAATTACGATATTGATCGTATTCGTCTCTTTTTAGAGAAAAAAGAAAAATAA
4178.2
ATGAATAAATCAGAACACCGCCACCAACTTATACGCGCTCTTATCACAAAAAACAAGATTCATACACAGGCTGAGTTGC
AAGCCCTTCTTGCTGAGAACGACATTCAAGTAACCCAGGCAACCCTCTCACGCGACATCAAAAATATGAACCTATCAAA
AGTCCGCGAAGAAGATAGCGCTTATTATGTTCTTAACAATGGTTCCATCTCAAAATGGGAAAAACGTCTCGAACTCTAC
ATGGAAGACGCCCTTGTCTGGATGCGCCCAGTTCAACACCAAGTCCTACTAAAAACCCTTCCTGGACTGGCTCAATCCT
TTGGTTCTATCATTGATACTTTGAGCTTCCCTGACGCTATCGCTACCCTTTGTGGTAATGATGTCTGTCTTATCATCTG
TGAAGATGCAGATACTGCTCAAAAGTGCTTTGAAGAACTGAAAAAATTCGCCCCACCATTTTTCTTTGAAGAATAA
4179.1
ATGAAAAGTATAAAATTAAATGCTCTATCTTACATGGGAATTCGTGTCTTGAATATTATTTTTCCCATCCTAACTGGAA
CCTATGTCGCGCGTGTCTTGGACCGAACTGACTATGGTTACTTCAACTCAGTCGACACTATTTTGTCATTTTTCTTGCC
CTTTGCAACTTATGGTGTCTATAACTACGGTTTAAGGGCTATCAGTAATGTCAAGGATAACAAAAAAGATCTTAACAGA
ACCTTTTCTAGTCTTTTTTATTTGTGCATCGCTTGTACGATTTTGACCACTGCTGTCTATATCCTAGCCTATCCTCTCT
TCTTTACTGATAATCCAATCGTCAAAAAGGTCTACCTTGTTATGGGGATTCAACTCATTGCCCAGATTTTTTCAATCGA
ATGGGTCAATGAAGCTCTGGAAAATTACAGTTTTCTCTTTTACAAAACTGCCTTCATCCGTATCCTGATGCTGGTCTCT
ATTTTCTTATTTGTTAAAAATGAACACGATATTGTTGTCTATACACTTGTGATGAGTTTATCGACGCTGATTAACTACC
TGATTAGTTATTTTTGGATTAAAAGAGACATCAAACTTGTTAAAATTCACCTAAGTGATTTTAAACCACTCTTTCTCCC
TCTGACAGCCATGTTAGTCTTTGCCAATGCCAATATGCTCTTCACTTTTTTAGATCGCCTCTTCCTCGTTAAAACAGGG
ATTGATGTCAACGTTAGTTACTATACCCATAGCTCAGCGAATTGTGACCGTTATAGCTGGGGTTGTAACAGGTGCAATT
GGAGTGAGTGTGCCTCGTCTCAGTTACTATCTGGGGAAAGGAGACAAAGAAGCCTATGTTTCTCTGGTTAATAGAGGTA
GTCGAATCTTTAACTTCTTTATCATTCCACTGAGTTTTGGACTCATGGTTTTAGGACCAAATGCCATCCTACTTTACGG
TAGTGAAAAATATATCGGAGGCGGCATCTTGACCTCTCTCTTCGCTTTTCGTACGATTATCCTGGCCTTAGATACCATT
CTTGGTTCCCAAATTCTCTTTACCAATGGCTATGAAAAAACGTATCACAGTCTATACAGTCTTTGCTGGGCTACTCAAT
TTGGGCTTGAATAGTCTCCTTTTTTTCAACCATATCGTGGCTCCTGAATACTACTTACTGACAACTATGCTATCAGAGA
CTTCTCTACTTGTTTTTCTATATCATTTTCATCCATAGAAAACAACTCATCCACTTGGGACATATCTTTAGCTATACTG
TTCGATACTCTCTCTTTTCACTTTCCTTTGTAGCAATTTATTTCCTGATTAATTTCGTGTATCCTGTAGATATGGTCAT
TAATTTGCCATTTTTGATTAATACTGGTTTGATTGTCTTGCTATCAGCTATCTCTTATATTAGTCTACTTGTCTTCACA
AAAGATAGCATTTTCTATGAATTTTTAAACCATGTCCTAGCCTTAAAAAATAAATTTAAAAAATCATAG
4179.2
ATGAAACAACTAACCGTTGAAGATGCCAAACAAATTGAATTAGAAATTTTGGATTATATTGATACTCTCTGTAAAAAGC
ACAATATCAACTATATTATTAACTACGGTACTCTGATTGGGGCGGTTCGACATGAGGGCTTTATCCCTTGGGACGACGA
TATTGATCTGTCCATGCCTAGAGAAGACTACCAACGATTTATTAACATTTTTCAAAAGGAAAAAAGCAAGTATAAGCTC
CTATCCTTAGAAACTGATAAGAACTACTTTAACAACTTTATCAAGATAACCGACAGTACGACTAAAATTATTGATACTC
GAAATACAAAAACCTATGAGTCTGGTATCTTTATCGATATTTTCCCTATAGATCGCTTTGATGATCCTAAGGTCATTGA
TACTTGTTATAAACTGGAAAGCTTCAAACTGCTGCTTTCAGTAAACATAAAAATATTGTCTATAAGGATAGCCTTTTAA
AAGATTGGATACGAACAGCCTTCTGGTTACTCCTTCGACCGGTTTCTCCTCGTTATTTTGCAAATAAAATCGAGAAAGA
AATTCAAAAATATAGTCGTGAAAATGGGCAATATATGGCTTTTATCCCTTCAAAATTTAAGGAAAAGGAAGTCTTCCCA
AGTGGTACCTTTGATAAAACAATCGATTTACCCTTTGAGAATTTAAGCCTTCCTGCACCTGAAAAATTTGATACTATTT
TGACACAATTTTATGGAGATTATATGACCCTACCACCAGAAGAAAAACGCTTCTACAGTCATGAATTTCACGCTTATAA
AGGAGGATTAG
4179.3
ATGATAAAAATCAATCATCTAACCATCACACAAAACAAAGATTTACGAGATCTTGTATCTGACCTAACCATGACCATCC
AAGACGGGGAAAAGGTTGCTATTATTGGTGAAGAAGGAAATGGCAAATCAACCTTACTTAAAATTTTAATGGGGGAAGC
TTTGTCTGATTTCACTATCAAGGGAAACATCCAATCTGACTATCAGTCACTGGCCTACATTCCTCAAAAAGTCCCTGAG
GACCTAAAAAGAAAACTTTACACGACTACTTCTTTTTAGATTCTATTGATTTAGACTACAGTATCCTCTATCGTTTGGC
GGAGGAATTGCATTTTGATAGCAATCGTTTCGCAAGTGACCAAGAGATTGGCAATCTATCAGGGGGCGAAGCTTTGAAA
ATTCAGCTTATCCATGAGTTAGCCAAACCCTTTGAGATTCTATTTTTAGATGAACCTTCAAATGACCTAGACCTTGAGA
CAGTTGATTGGCTAAAAGGCCAGATTCAAAAGACCAGGCAAACCGTTATTTTCATTTCCCATGATGAAGACTTTCTTTC
TGAAACGGCAGACACTATTGTTCACTTGCGACTGGTCAAACACCGTAAAGAAGCGGAAACGCTAGTAGAGCATTTAGAC
TATGATAGCTATAGTGAGCAGAGAAAGGCTAATTTTGCCAAACAAAGTCAGCAAGCTGCTAACAACCAAAGAGCCTACG
ATAAAACCATGGAAAAACATCGGAGAGTTAAGCAAAATGTAGAAACTGCGCTTCGAGCTACCAAAGATAGTACTGCCGG
TCGCCTATTGGCTAAAAAGATGAAAACTGTCCTCTCACAAGAAAAACGCTACGAAAAGGCAGCTCAGTCCATGACTCAA
AAGCCACTTGAAGAGGAACAAATCCAACTTTTCTTTTCAGACATCCAACCATTACCAGCTTCTAAAGTCTTAGTCCAAC
TGGAAAAAGAAAATTTGTCCATTGACGACCGAGTTTTGGTTCAAAAACTACAACTAACTGCCGTGGCCAAGAAAAAATC
GGTATTATCGGGCCAAATGGTGTTGGGAAATCAACTCTGTTAGCCAAGTTACAGAGACTTCTGAATGATAAAAGAGAGA
TTTCACTTGGTTTTATGCCACAAGATTACCACAAAAAACTGCAATTGGATTTATCCCCAATAGCCTATCTCAGTAAAAC
TGGGGAAAAAGAGGAACTACAGAAAATCCAATCTCACCTAGCTAGTCTCAATTTCAGTTATCCAGAAATGCAGCATCAA
ATTCGCTCCTTATCTGGCGGACAACAGGGAAAACTCCTGCTTTTGGATTTAGTCCTGCGCAAACCAAACTTTCTCCTGC
TGGATGAACCCACACGAAACTTTTCTCCCACTTCTCAACCCCAAATCAGAAAACTCTTTGCTACCTATCCAGGCGGTCT
CATCACTGTTTCGCATGACCGTCGTTTCTTAAAAGAAGTCTGCTCGATCATCTATCGCATGACAGAACACGGTTTTGAA
GCTAGTTAATTTAGAAGATTTATAA
4179.4
ATGAAACCAAAAACATTTTACAACTTGCTTGCCGAGCAGAATCTTCCACTTTCGGACCAGCAAAAAGAACAATTTGAAC
GTTATTTTGAGCTCTTGGTCGAGTGGAATGAGAAGATTAATTTGACGGCGATTACGGACAAGGAAGAAGTTTATCTCAA
ACATTTTTACGATTCGATTGCACCCATTCTTCAAGGTTTGATTCCCAATGAAACTATCAAACTTCTTGATATCGGGGCT
GGGGCAGGATTTCCTAGTCTACCAATGAAAATTCTCTATCCGGAGTTAGATGTGACCATTATTGATTCACTCAATAAGC
GCATCAACTTCCTACAACTCTTGGCTCAAGAACTGGATTTGAACGGAGTTCATTTCTACCACGGACGTGCCGAAGATTT
TGCCCAAGACAAGAACTTCCGTGCTCAATATGATTTTGTAACAGCTCGTGCGGTTGCCCGTATGCAGGTCCTATCTGAA
TTGACTATTCCCTACCTTAAGGTTGGTGGCAAACTATTAGCACTCAAGGCTAGCAATGCGCCTGAGGAATTATTAGAAG
CTAAGAATGCCCTCAATCTCCTTTTTAGTAAGGTCGAAGACAATCTCAGctACGCCCTACCGAATAGAGATCCGCGCTA
TATCACAGTGGTAGAAAAGAAAAAAGAAACACCAAATAAATATCCACGTAAGGCTGGTATGCCAAATAAACGCCCACTT
TAA
4179.6
ATGAGTATTAAACTAATTGCCGTTGATATCGACGGAACCCTTGTCAACAGCCAAAAGGAAATCACTCCTGAAGTTTTTT
CTGCCATCCAAGATGCCAAAGAAGCTGGTGTCAAAGTCGTGATTGCAACTGGCCGCCCTATCGCAGGCGTTGCCAAACT
TCTAGACGACTTGCAGTTGAGAGACGAGGGGGACTATGTGGTAACCTTCAACGGTGCCCTTGTCCAAGAAACTGCTACA
GGACATGAGATTATCAGCGAATCCTTGACTTATGAGGATTATCTAGATATGGAATTCCTCAGTCGCAAGCTCGGTGTCC
ACATGCATGCCATTACCAAGGACGGTATCTATACTGCAAATCGCAATATCGGAAAATACACTGTACACGAATCAACCCT
CGTCAGCATGCCTATCTTCTACCGTACCCCTGAAGAAATGGCTGGCAAAGAAATTGTTAAATGTATGTTTATCGATGAA
CCAGAAATTCTCGATGCTGCGATTGAAAAAATTCCAGCAGAATTTTACGAGCGCTACTCCATCAACAAATCTGCTCCTT
TCTACCTCGAACTCCTTAAAAAGAATGTAGACAAGGGTTCAGCCATTACTCACTTGGCTGAAAAACTCGGATTGACCAA
AGATGAAACCATGGCAATCGGTGATGAAGAAAATGACCGTGCCATGCTGGAAGTCGTTGGAAACCCCGTTGTCATGGAA
AATGGAAATCCAGAAATCAAAAAAATCGCCAAATACATCACCAAAACAAATGACGAATCCGGCGTTGCCCATGCCATCC
GAACATGGGTACTGTAA
4179.7
ATGACTTGGATTATTCTTGGAGTTATCGCTCTTATTGTTATTTTTGTGATTGTTAGCTATAACGGTTTGGTTAAAAATC
GTATGCAAACCAAGGAGGCTTGGAGTCAGATTGATGTTCAGTTGAAACGTCGCAATGACCTCTTGCCAAACTTGATTGA
GACTGTAAAAGGTTATGCCAAATATGAAGGTTCTACCCTTGAAAAGGTGGCAGAACTACGTAACCAAGTGGCGGCAGCG
ACTTCACCAGCAGAAGCTATGAAAGCCAGTGATGCCCTCACTCGTCAGGTTTCAGGTATTTTTGCAGTTGCAGAAAGCT
ATCCAGATTTGAAAGCTAGTGCTAACTTTGTTAAATTGCAAGAGGAGTTGACAAACACAGAAATAAAATTTCTTACTCT
CGTCAACTCTATAACAGTGTTGTCAGCAACTACAATGTAAAATTAGAAACTTTCCCGAGCAATATTATCGCTGGAATGT
TTGGATTTAAAGCGGCAGATTTCCTTCAAACACCTGAAGAGGAAAAGTCGGTTCCTAAAGTTGATTTTAGCGGTTTAGG
TGACTAA
4179.8
ATGTTGTTTGATCAAATTGCAAGCAATAAACGAAAAACCTGGATTTTGTTGCTGGTATTTTTCCTACTCTTAGCTCTTG
TTGGTTATGCGGTTGGTTATCTCTTTATAAGATCTGGACTTGGTGGTTTGGTTATTGCACTGATTATCGGCTTTATCTA
CGCTTTGTCTATGATTTTTCAATCGACAGAGATTGTCATGTCCATGAATGGAGCGCGTGAGGTGGATGAGCAAACGGCA
CCAGACCTCTACCATGTAGTGGAAGATATGGCTCTGGTCGCTCAGATTCCATGCCCCGTGTTTTCATCATTGATGATCC
AGCCTAAATGCCTTTGCGACAGGTTCTAATCCTCAAAATGCGGCTGTTGCTGCGACTTCAGGTCTACTAGCTATCATGA
ATCGTGAAGAACTAGAAGCTGTTATGGGACATGAAGTCAGTCATATTCGTAATTATGATATCCGTATTTCGACTATTGC
AGTTGCCCTTGCTAGTGCTATCACCATGCTTTCTAGTATGGCAGGTCGTATGATGTGGTGGGGTGGAGCAGGTCGCAGA
CGAAGTGATGATGACCGAGATGGAAATGGTCTTGAAATCATTATGCTAGTGGTTTCCCTACTAGCTATTGTACTGGCAC
CTCTCGCTGCAACCTTGGTTCAGCTCGCTATTTCTCGTCAGAGGGAATTTCTGGCAGATGCATCTAGTGTCGAGCTGAC
TCGCAATCCCCAGGGAATGATTAATGCCCTAGATAAGTTGGACAATAGCAAACCTATGAGTCGCCACGTCGATGATGCT
AGCAGTGCCCTTTATATCAATGATCCTAAGAAAGGTGGGGGGTTCCAAAAACTCTTTTATACCCACCCACCTATCTCAG
AACGGATTGAACGTTTAAAACAGATGTAA
4179.9
ATGAAATTAAATATTCAAGAAATTCGTAAGCAGTCTGAAGGTTTTGAACTTTGAACAAACGTTAGATTTAGTTGATGAC
CTGCGTGCACGTAATCAAGAAATTTAGATGTAAAAGATATCCTTGCAGTTGGGAAAGTACAATATGAAGACCGTATGTA
TTTCTTAGATTATCAACTATCTTATACCATTGTTCTTCGTTCGAGTCGCAGTATGGAGCCAGTTGAGTTAGTTGAATCT
TATCCAGTCACGGAAGTTTTCATGGAAGGCGCAACTAACCAGCTAGATCAAGAAGTTTTAGATGATGACTTGGTCTTGC
CCATCGAAAATGGGGAGCTTGACCTTGCTGAGAGTGTATCAGACAATATCCTGCTAAACATTCCTATCAAGGTCTTGAC
GGCTGAAGAAGAAGCTGGTCAAGGATTTATCTCAGGAAATGACTGGCAAATCATGACAGAGGAAGAATACCAAGCTCAA
AAAGCAGTAAAGAAAGAAGAAAACAGTCCTTTTGCTGGCTTACAAGGACTATTTGACGGAGATGAATAA
4179.12
ATGGAGTTATTTATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGA
AAGTGCTAGAATACGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTGCCGTAATCC
AGCCGTTTTTATGGAACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCA
TTTTAGATGACTGTTATCCTTGGGATTTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTG
ACCTCCTGAAATTCCCGAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGT
CATTCAAGGCTTGGAAAATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCT
CTTCAGAATGGCGGAAAAACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGC
AAGACTACATCGGCAATGACCATCTGGTTCTAAGTGAATATGGACCTGGTGAACAACCTCTGAAATTTCATTTTCCTGC
CCGTAATCGCATCATTGCTGGACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACG
TGTGAGCGAGCAATGGAAGAAGGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCC
ATCATTTGATTCAAGAAGGAGCAAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA
4181.1
ATGAAACGTCAATTAGCCTTGGTCGTCTTTAGTGGTGGTCAAGATTCAACAACCTGCCTTTTCTGGGTCATGCAACACT
ATGAAACAGTCGAAGCTGTCACCTTTGCCTACGGCCAACGTCATCACCTCGAAATTCAAATTACTAGAGAAATCGCTAA
GGAACAGGGCATTCGTCACCATATCCTCGATATGTCTCTGCTGGGACAAATCACTGCTCAGCCAGACTTTGCGACGATT
CATATTTCCTACATTCCTGACAAGCTCTGTGTCGAGTCAAAATCCCTCAAACTATATCTATTTAGCTACCGAAACCACG
GAGATTTCCACGAAAACTGTATCAACACCATCGGGAAAGACTTGGTCAACTTGCTAGACCCTCGCTATTTAGAAGTCTG
GGGAAAATTCACTCCGCGCGGTGGCATTTCAATCGACCCCTACTACAACTACGGTAAGCAAGGAACTAAGTATGAGGGC
TTGGCAGAACAACGCCTCTTCCAACACGACCTTTATCCAGAGAAAATTGACAACCGCTAA
4181.2
ATGACCGAAACGGTAGAAGATAAAGTAAGTCATTCAATTACTGGGCTTGATATCCTCAAGGGGATAGTTGCTGCGGGAG
CTGTCATAAGTGGAACCGTTGCAACTCAAACGAAGGTATTTACAAATGAGTCAGCAGTACTTGAAAAAACTGTAGAGAA
AACGGATGCTTTGGCAACAAATGATACAGTAGTTCTAGGTACGATATCTACAAGTAATTCAGCGAGTTCAACTAGTTTG
TCAGCTTCAGAGTCGGCAAGTACATCTGCATCTGAGTCAGCCTCAACCAGCGCTTCGACCTCAGCAAGTACAAGTGCAT
CAGAATCAGCAAGTACATCGGCTTCGACAAGTATTTCTGCATCATCTACTGTGGTAGGTTCACAAACAGCTGCCGCTAC
AGAAGCAACTGCTAAGAAGGTCGAAGAAGATCGTAAGAAACCAGCTAGTGATTATGTAGCATCAGTTACAAATGTCAAT
CTCCAATCTTATGCTAAGCGACGCAAGCGTTCAGTGGATTCCATCGAGCAATTGCTGGCTTCTATAAAAAATGCTGCTG
TTTTTTCTGGCAATACGATTGTAAATGGCGCCCCTGCAATTAATGCAAGTCTAAACATTGCTAAAAGTGAGACAAAAGT
TTATACAGGTGAAGGTGTAGATTCGGTATATCGTGTTCCAATTTACTATAAATTGAAAGTGACAAATGATGGTTCAAAA
TTGACCTTTACCTATACGGTTACGTATGTGAATCCTAAAACAAATGATCTTGGTAATATATCAAGTATGCGTCCTGGAT
ATTCTATCTATAATTCAGGTACTTCAACACAAACAATGTTAACCCTTGGCAGTGATCTTGGTAAACCTTCAGGTGTAAA
GAACTACATTACTGACAAAAATGGTAGACAGGTTCTATCCTATAATACATCTACAATGACGACGCAGGGTAGTGGGTAT
ACTTGGGGAAATGGTGCCCAAATGAAGGTTTCTTTGCTAAGAAAGGATATGGATTAACATCATCTTGGACTGTACCAAT
TACTGGAACGGATACATCCTTTACATTTACCCCTTACGCTGCTAGAACAGATAGAATTGGAATTAACTACTTCAATGGT
GGAGGAAAGGTAGTTGAATCTAGCACGACCAGTCAGTCACTTTCACAGTCTAAGTCACTCTCAGTAAGTGCTAGTCAAA
GCGCCTCAGCTTCAGCATCAACAAGTGCGTCGGCTTCAGCATCAACCAGTGCCTCGGCTTCAGCGTCAACCAGTGCGTC
AGCTTCAGCAAGTACCAGTGCTTCAGTCTCAGCATCAACAAGTGCTTCAGCCTCAGCATCGACAAGTGCCTCGGCTTCA
GCAAGCACATCAGCATCTGAATCAGCGTCAACCAGTGCTTCGGCTTCAGCAAGTACCAGTGCTTCAGCTTCAGCATCAA
CCAGCGCCTCGGCCTCAGCAAGCACCTCAGCTTCTGAATCGGCCTCAACCAGCGCCTCGGCCTCAGCAAGCACCTCAGC
TTCTGAATCGGCCTCAACCAGCGCCTCAGCCTCAGCATCAACGAGTGCTTCGGCTTCAGCAAGCACAAGCGCCTCGGGT
TCAGCATCAACGAGTACGTCAGCTTCAGCGTCAACCAGTGCTTCAGCCTCAGCATCAACAAGTGCGTCAGCCTCAGCAA
GTATCTCAGCGTCTGAATCGGCATCAACGAGTGCGTCTGAGTCAGCATCAACGAGTACGTCAGCCTCAGCAAGCACCTC
AGCTTCTGAATCGGCCTCAACCAGTGCGTCAGCCTCAGCATCGACAAGCGCCTCAGCTTCAGCAAGTACCAGTGCTTCA
GCCTCAGCGTCGACAAGTGCGTCGGCCTCAACCAGTGCATCTGAATCGGCATCAACCAGTGCGTCAGCCTCAGCAAGTA
CTAGTGCATCGGCTTCAGCATCAACCAGTGCCTCGGCTTCAGCGTCAACCAGTGCGTCAGCTTCAGCAAGTACCAGTGC
TTCAGTCTCAGCATCAACAAGTGCTTCAGCCTCAGCATCGACAAGTGCCTCGGCTTCAGCAAGCACATCAGCATCTGAA
TCAGCGTCGACAAGCGCCTCAGCTTCAGCAAGTACCAGTGCGTCAGCTTCAGCATCAACCAGCGCCTCGGCCTCAGCAA
GCACCTCAGCTTCTGAATCGGCCTCAACCAGCGCCTCGGCCTCAGCAAGCACCTCAGCTTCTGAATCGGCCTCAACCAG
CGCCTCAGCCTCAGCATCAACGAGTGCTTCGGCTTCAGCAAGCACAAGCGCCTCGGGTTCAGCATCAACGAGTACGTCA
GCTTCAGCGTCAACCAGTGCTTCAGCCTCAGCATCAACAAGTGCGTCAGCCTCAGCAAGTATCTCAGCGTCTGAATCGG
CATCAACGAGTGCGTCTGAGTCAGCATCAACGAGTACGTCAGCCTCAGCAAGCACCTCAGCTTCTGAATCGGCCTCAAC
CAGTGCGTCAGCCTCAGCATCGACAAGCGCCTCAGCTTCAGCAAGTACCAGTGCTTCAGCCTCAGCTCGACAAGTGCGT
CGGCCTCAACCAGTGCATCTGAATCGGCATCAACCAGTGCGTCAGCCTCAGCAAGTACTAGTGCATCAGCTTCAGCATC
AACGAGTGCATCGGCTTCAGCATCAACCAGTGCCTCGGCTTCAGCGTCAACCAGTGCGTCAGCTTCAGCAAGTACCAGT
GCTTCAGTCTCAGCATCAACAAGTGCTTCAGCCTCAGCATCGACAAGTGCcTCGGCTTCAGCAAGCACATCAGCATCTG
AATCAGCGTCGACAAGCGCCTCAGCTTCAGCAAGTACCAGTGCGTCAGCCTCAGCGTCGACAAGTGCGTCAGCCTCAGC
AAGTACTAGTGCATCAGCTTCAGCATCAACGAGTGCATCGGCTTCGGCGTCAACCAGTGCATCAGAGTCAGCAAGTACC
AGTGCGTCAGCTTCCGCATCAACAAGTGCCTCGGCTTCAGCAAGCACCAGTGCGTCGGCTTCAGCAAGTACTAGCGCCT
CAGCCTCAGCCTCAACCAGTGCGTCAGCCTCAGCAAGTATCTCAGCGTCTGAATCGGCATCAACGAGTGCGTCCGCTTC
AGCAAGTACTAGCGCCTCAGCCTCAGCGTCAACAAGTGCATCGGCTTCAGCGTCAACGAGTGCGTCTGAATCGGCATCA
ACGAGTGCGTCCGCTTCAGCAAGTACTAGCGCCTCAGCCTCAGCGTCAACAAGTGCATCGGCTTCAGCATCAACGAGTG
CGTCCGCTTCAGCAAGTACTAGCGCCTCAGCCTCAGCGTCAACAAGTGCATCGGCTTCAGCGTCAACGAGTGCGTCTGA
GTCAGCATCAACGAGTGCGTCAGCCTCAGCAAGCACATCAGCTTCTGAATCTGCATCAACCAGTGCGTCAGCCTCAGCA
TCGACAAGCGCCTCAGCTTCAGCAAGTACCAGTGCGTCAGCCTCAGCGTCGACAAGTGCGTCGGCTTCAGCAAGTACCA
GTGCGTCAGCCTCAGCAAGTACCAGTGCGTCAGCCTCAGCGTCGACAAGTGCGTCGGCCTCAACCAGTGCATCTGAATC
GGCATCAACCAGTGCGTCAGCCTCAGCAAGTACTAGTGCATCAGCTTCAGCATCAACGAGTGCATCGGCTTCAGCATCA
ACCAGTGCATCAGAGTCAGCAAGTACCAGTGCGTCAGTTCCGCATCAACAAGTGCCTCGGCTTCAGCAAGTACTAG
4183.1
ATGGGGGTCGAAACTTGGTTTTATTCTAGCATCTGCTGGCTGGCCATCGGGCTTGGTTCCGTTTGGAAGTTTCCCTACA
TGACTGCTGCTAATGGCGGTGGAGGCTTTTTACTAATCTTTCTCATTTCCACTATTTTAATCGGTTTCCCTCTCCTGCT
GGCTGAGTTTGCCCTTGGCCGTAGTGCTGGCGTTTCCGCTATCAAAACCTTTGGAAAACTGGGCAAGAATAACAAGTAC
AACTTTATCGGTTGGATTGGCGCCTTTGCCCTCTTTATCCTCTTATCTTTTTACAGTGTTATCGGAGGATGGATTCTAG
TTATCTAGGTATTGAGTTTGGGAAATTGTTCCAACTTGGTGGAACGGGTGATTATGCTCAGTTATTTACTTCAATCATT
CAATCCAGCCATTGCCCTAGGAGCTCAAGCGGCCTTTATCCTATTGAATATCTTCATTGTATCACGTGGGGTTCAAAAA
GGGATTGAAAGAGCTTCGAAAGTCATGATGCCCCTGCTCTTTATCGTCTTTGTTTTTATCATCGGTCGCTCTCTCAGTT
TGCCAAATGCCATGGAAGGGGTTCTTTACTTCCTCAAACCAGACTTTTCAAAACTGACTAGCACTGGTCTCCTCTATGC
TCTGGGACAATCTTTCTTTGCCCTCTCACTAGGGGTTACAGTCATGTTGACCTATGCTTCTTACTTAGACAAGAAAACC
AATCTAGTCCAGTCAGGAATCTCCATCGTAGCCATGAATATCTCGATATCCATCATGGCAGGTCTAGCCATTTTCCAAG
CTCGATCCCCCTTCAATATCCAGTCTGAAGGGGGACCCAGCCTGCTCTTTATCGTCTTGCCTCAACTCTTTGACAAGAT
GCCTTTTGGAACCATTTTCTACGTCCTCTTCCTCTTGCTCTTCCTTTTTGCGACAGTCACTTTTCTGTCGTGATGCTGG
AAATCAATGTAGACAATATCACCAACCAGGATAACAGCAAACGTGCCAAATGGAGTGTTATTTTAGGAATTTTGACCTT
TGTCTTTGGCATTCCTTCAGCCCTATCTTACGGTGTCATGGCGGATGTTCACATTTTTGGTAAGACCTTCTTTGACGCT
ATGGACTTCTTGGTTTTCCAATCTCCTCATGCCATTTGGAGCTCTCTACCTTTCACTTTTTACAGGCTATATCTTTAAA
AAGGCTCTTGCAATGGAGGAACTCCATCTCGATGAAAGAGCATGGAAACAAGGACTGTTCCAAGTCTGGCTCTCCTTCT
TCGTTTCTTCGTTTCGTCATTCCAATCATCATCATTGTGGTCTTCATTGCCCAATTTATGTAATCAAAAAGGACTTGAG
TAG
4183.5
ATGTTGAAAAAATGGCAGTTAAAAGATGTTATCTTGCTTGCTTTCTTGTCTATCTTTTTTTGCTGGGGTTTTCGTTGGT
TCAGGATATGTGTATAATATTCTCAGTCTACTCTTAACACCTCTGGTTTTGCAGGCCTTTGCCAATGAAATCCTCTTCG
GTCTCTGGTGTATGGCTGCGCCCATTGCTGCCATCTGTTCCGAGAGTCGGAAGTGCAACGATTGGAGAAGTGCTAGCTG
CGCTTGCTGAAGTCCTTTATGGTAGCCAATTTGGTCTAGGAGCTCTTTGTCTGGCTTTGTTCAAGGTTTGGGAAGTGAA
TTTGGTTTTATCGTAACTAAGAATCGCTATGAAAGTTGGCTCTCTCTAACTGCTAATAGTATTGGGATTACGCTTGTTA
GCTTTGTCTATGAATACATTAAGTTAGGTTACTACGCCTTTTCCCTTCCGTTTGTCCTTTCCTTTGCTTGTGGTACGTT
TTATTTCTGTTTATTTCTCTGTACCATCTTGGTTCGTGCCATTGTCAAACTCTATCATCAGTTTGCAACTGGAGGAAAA
GCATAG
4183.6
ATGGTCAAAGTAGCAACCCAGACACCGATTATCAGTCTCTTCTTGCTGATTTTATCCTTGGAAACATCTTTCATTCCTT
CGATTGCTCTGACTCTTTCGGTAGTCGCATTTTGTATTCTCTTTATGCTCTATTACCGTCGATTTAAAATGTTAGCTTG
GATGATCATACTTGCCATTTTTACCATCTTTTTGCCAACTACTGGGCAGTTCAGTTACACGGAGATGCTTCACAGGCAG
TCATGCTTGGAACGAGGGCCTTTGTGACAGTTTGTATCGGCCTTGTCTTTGTTTCCTCTGTTTCACTAAAAGAGCTTCT
CTTGTACTTGGCTCAAAAGGGGCTATCACGCTCTTGGTCCTATGCCTTGATTGTGGTATTCAATTCTTTTCCTCTCATT
CAGCAAGAAATCAAGTCCCTCAAAGAAGCTTCGGTATTACGTGGTCAAGAACTACATTTTTGGTCGCCCTTGATTTACA
GTAAGGTTCTGATGACAGTCTTTAGGTGGCGCCATCTTTACCTGAGAGCTCTATCTGCTCACGGATATGACGAACATGC
ACAGTTGAAGAATAGCTATCGGACTTTTTATATTCCTAAAAAAACAAAATTAATCTACCTGCTTTTCTTTTTATTGCTT
CAAACCAGTCTATTTTTATAA
4183.7
ATGAGAAAGCACCAATTACAAGTTCACAAATTAACCATTTTATCTATGATTGGCCCTTGATGTAGTCCTTACACCTATC
TTTCGAATTGAGGGAATGGCACCGATGTCCAGTGTAGTCAATATTCTAGCAGGAATCATGATGGGACCTGTTATGCCTT
GGCTATGGCTACAGTCACAGCCTTTATCCGTATGACGACTCAAGGGATTCCGCCTTTAGCTCTCACAGGAGCGACTTTT
GGAGCCCTTCTAGCAGGTCTCTTTTATAAGTACGGTCGAAAATTTCACTATTCTGCTCTAGGAGAGATTTTGGGAACAG
GTATTATTGGTTCCATTGTTTCCTATCCTGTTATGGTACTCTTTACAGGATCAGCTGCTAAGCTTAGCTGGTTTATCTA
CACGCCTCGATTTTTCGGAGCAACCTTGATTGGTACAGCGATTTCCTTTATTGCCTTTCGATTTTTAATCAAGCAGGAA
TTCTTTAAAAAAGTGCAGGGATATTTCTTTAGTGAAAGGATAGACTGA
4183.8
ATGCAGGAATTTACAAATCCCTTTCCTATAGGCTCTAGTTCCCTCATTCACTGCATTACCAATGAGATTTCTTGTGAGA
TGCTGGCAAATGGGATTTTGGCTCTGGGATGCAAACCTGTCATGGCAGATGATTCCCGTGAAGTTCTTGATTTTACTAA
GCAAAGTCAGGCTCTCTTCATCAATTTGGGGCATTTGTCAGCTGAGAAGGAAAAAGCAATCCGCATGGCAGCTTCGTAT
GCAAACCAATCTTCTCTCCCGATGGTAGTAGATGCGGTTGGCGTAACGACTTCATCCATTCGTAAGAGCTTAGTTAAAG
ACCTTTTAGACTATAGACCTACGGTCCTTAAAGGAAACATGTCAGAAATTCGAAGTCTTGTTGGATTAAAGCACCACGG
CGTTGGGGTCGATGCGAGTGCTAAAGATCAAGAAACGGAGGATTTGCTTCAAGTCTTGAAAGACTGGTGTCAGACCTAT
CCTGGTATGTCTTTCTTAGTCACAGGTCCCAAGGACCTCGTCGTTTCGAAAAATCAGGTCGCTGTACTGGGAAATGGCT
GTACTGAATTAGACTGGATAACAGGGACAGGAGACTTGGTTGGAGCCTTAACAGCTGTTTTTCTCAGCCAAGGAAAGAC
TGGTTTTGAAGCTTCTTGCTTAGCAGTCTCTTATCTCAATATCGCTGCTGAGAAAATAGTGTTCAAGGAATGGGATTGG
AAGAATTTCGTTACCAAGTACTCAATCAGCTTTCGCTCCTAAGAAGAGATGAAAATTGGCTAGATACCATCAAAGGAGA
GGTTTATGAATAG
4185.3
ATGAACCATAAAATCGCAATTTTATCAGATGTTCATGGCAATGCGACGGCGCTAGAAGCAGTGATTGCAGATGCTAAAA
ATCAAGGGGCCAGTGAATATTGGCTTCTGGGAGATATTTTTCTTCCTGGTCCAGGCGCAAATGACTTAGTCGCCCTGCT
AAAGGACCTTCCTATCACAGCAAGTGTTCGAGGCAATTGGGATGATCGTGTCCTTGAGGCTTTAGATGGGCAATATGGC
TTAGAAGACCCACAGGAAGTTCAGCTCTTGCGTATGACACAGTATTTGATGGAGCGAATGGATCCTGCAACGATTGTCT
GGCTACGAAGCTTGCCTTTGCTGGAAAAGAAAGAAATTGACGGATTGCGCTTTTCTATCTCTCATAATTTACCTGACAA
AACTATGGTGGTGACTTGCTAGTTGAGAATGATACAGAGAAATTTGACCAACTGCTAGATGCGGAAACGGACGTGGCAG
TTTATGGTCATGTTCACAAGCAGTTGCTTCGTTATGGAAGTCAAGGGCAACAAATCATCAATCCAGGGTCGATTGGCAT
GCCCTATTTTAATTGGGAGGCGTTAAAAAATCACCGTTCCCAGTATGCCGTGATAGAAGTTGAAGATGGGGAATTACTC
AATATCCAATTTCGTAAAGTTGCTTATGATTACGAAGCTGAGTTAGAATTGGCCAAGTCCAAGGGGCTTCCCTTTATCG
AAATGTATGAAGAACTGCGTCGTGACGATAACTATCAGGGGCACAATCTGGAATTATTAGCCAGCTTAATAGAAAAGCA
TGGGTATGTAGAGGATGTGAAGAATTTTTTTGATTTTTTGTAA
4186.1
ATGAATGTAAATCAGATTGTACGGATTATTCCTACTTTAAAAGCTAATAATAGAAAATTAAATGAAACATTTTATATTG
AAACCCTTTGGAATGAAGGCCTGTTAGAAGAATCGGCCTTTCTGTCACTAGGTGACCAAACGGCTCTTGAAAAGCTGGT
TTTAGAAGAAGCTCCCAGTATGCGTACTCGTAAGGTAGAGGGAAGAAAAAAACTAGCTAGATTGATTGTCAAGGTGGAA
AATCCCTTAGAAATTGAAGGAATCTTATCTAAAACAGATTCGATTCATCGATTATATAAAGGTCAAAATGGCTACGCTT
TTGAAATTTTCTCACCAGAAGATGATTTGATTTTGATTCATGCGGAAGATGACATAGCAAGTCTAGTAGAAGTAGGAGA
AAGCCTGAATTTCAAACAGATTTGGCATCAATTTCTTTAAGTAAATTTGAGATTTCTATGGAATTACATCTCCCAACTG
ATATCGAAAGTTTCTTGGAATCATCTGAAATTGGGGCATCCCTTGATTTTATTCCAGCTCAGGGGCAGGATTTGACTGT
GGACAATACGGTTACCTGGGACTTATCTATGCTCAAGTTCTTGGTCAATGAATTAGACATAGCAAGTCTCGCCAGAAGT
TTGAGTCTACTGAATATTTTATTCCTAAGTCTGAAAAATTCTTCCTTGGTAAAGATAGAAATAATGTTGAATTGTGGTT
TGAAGAAGTATGA
4186.2
ATGAAGTGGACCAAGATTATTAAAAAAATAGAAGAACAAATCGAGGCAGGGATTTTATCCCGGAGCCTCTTTTGCGTAT
TTTAAGGACAATCAATGGACAGAGTTCTATTTAGGCCAGAGTGACCCAGAGCATGGCTTGCAGACTGAGGCAGGACTAG
TTTATGACCTAGCTAGTGTCAGCAAGGTTGTTGGGGTTGGCACAGTTTGTACCTTCTTGTGGGAAATAGGTCAATTAGA
TATTGATAGACTGGTAATAGATTTTTTACCTGAGAGTGATTATCCAGACATCACTATTCGCCAGCTCTTGACTCATGCA
ACAGACCTTGATCCTTTTATTCCTAATCGTGATCTTTTAACAGCCCCTGAATTAAAGGAAGCGATGTTTCATCTCAACA
GACGAAGTCAGCCAGCCTTTCTTTATTCGGATGTCCATTTTTTGCTGTTGGGCTTTATTTTGGAAAGAATTTTTAATCA
AGATTTGGATGTGATTTTAAAGGATCAAGTCTGGAAACCTTGGGGAATGACGGAAACTAAGTTTGGGCCAGTTGAGCTT
GCTGTTCCAACAGTTAGAGGTGTAGAGGCAGGCATAGTGCATGATCCCAAGGCTCGTCTCCTGGGTAGACATGCTGGGA
GTGCTGGTTTATTTTCGACTATAAAGGATTTACAAATCTTTTTAGAACACTATTTAGCAGATGATTTTGCAAGAGACTT
AAATCAAAATTTTTCTCCTTTGGATGACAAGGAACGTTCTTTAGCATGGAATTTGGAAGGAGATTGGCTAGACCATACG
GGCTATACAGGTACCTTTATCATGTGGAATCGTCAGAAGCAAGAAGCCACTATTTTCCTATCGAATCGTACCTATGAAA
AGGACGAGAGAGCTCAATGGATATTAGACCGCAATCAAGTGATGAACTTGATTCGCAAAGAAGAGTAA
4187.2
ATGATGAAGAAGACTTATAATCATATTTTGGTCTGGGGAGTCATTTTCTATAGCATTTGCATTGTCTGTTTTTGCTTTA
CTCCTCAAGAACAATCTACCGTGGGAGTGGGAACTCCAGGTATTCAGCATCTTGGACGCCTGGTTTTTCTTTTGACTCC
TTTCAATTCTCTCTGGAAACTGGGCGAAGTGAGTGACATTGGACAATTATGTTGGATTTTTTTACAAAATATCCTCAAT
GTCTTCTTGTTTTTTCCTCTGATTTTCCAACTCCTTTATCTATTTCCAAATTTGCGGAAAACAAAAAAGGTCCTTCTTT
TTAGTTTTCTTGTGAGTCTTGGAATCGAGTGTACGCAATTAATCTTGGACTTTTTCTTTGATTTCAATCGCGTCTTTGA
GATTGATGATTTGTGGACCAACACTTTGGGTGGCTATCTGGCTTGGCTCCTTTATAAACGATTACATAAAAACAAGGTA
AGGAATTAA
4188.1
ATGAAGATTCCTCTCTTAACTTTTGCAAGGCATAAATTTGTTTATGTCTTGCTTACTTTGCTTTTTTCTTGCTTTGGTT
TATCGTGATGTTTTGATGACTTATTTCTTTTTTGATATTCATGCGCCCGATCTAGCTAAATTCGATGGACAAGCAATTA
AAAATGACTTATTAAAATCAGCATTAGATTTTCGTATTTCTCCAGTTCAATCTAGGTTTTTATCAATCATTTATTATTC
CAATCATCATTGTTTTTGCTAGGTTTTCAATATATTGAGCTGAAAAATAAAGTTTTACGATTGAGTATTGGAAGAGAAG
TGAGTTATCAAGGGTTAAAAAGAAAGTTGACTTTGCAAGTTGCAAGTATCCCTTGTTTTGATATATTTAGTGACTGTGC
TGATAATTGCAATTATAACCTATTTCTTTGGGACTTTTCTCCTCTTGGATGGAATTCTCTATTTTCTGATGGAAGTGGT
TTACAAAGACTCCTAGATGGAGAGATAAAAAGCTATTTGTTCTTTACTTGTGTCCTACTAATCGGTATTTTCATCAATG
CAATCTATTTTTTACAAATAGTTGATTATGTGGGGAATGTGACTCGTTCGGCAATCACCTATTTGATGTTTCTTTGGCT
TGGTTCTATGCTGCTTTATAGTGCCTTGCCTTACTATATGGTTCCTATGACGAGTTTGATGCAAGCTAGCTATGGGGAT
GTAAGTTTGATGAAACTCTTTACTCCTTATATCCTTTATATTGTCCCTTACATGGTGCTTGAAAAATATGAAGATAATG
TTTAA
4188.2
ATGAAGATAATGTTTAAGAATTTTAACAATATTTTGCTAAATAGAAAGATTGTTTTACTACTTCGTATAGTTCTGATGA
TGATTTTGATAAACCATCTATTGTCAACAGCGGTTCAAAAGCAGGATGCTGTTATCTTTTTCAAGAGAGAATTGATTTC
AATTTTTTCCTATAATGACTATTCTGAAGCGAATTTAGAAATCCCCAAACTATTGTTAAACCTTTCGCTTTTCATGGTA
GGATGGCTCTCTGTCATTTTACTTGAAAGTGATTTGGCAGACCATTACCATCACTTGATTCGCTATCAATCAAGCTCCT
TTTTCGATTATACAAGGAAACGATTGGTTGTCATTTCTAAATTTTTTTACTCAAGATTTGTTTGTCTGGTTTCTTGGTT
TACTTCCTCTAGGAATTCATTTCAAAACAGTCGCACTTTTCTTTTTACTTGCTCAGTTAATGATGTTGTACTTACTACT
GTCTTATCTGATAGCACTGATTAGTGCGGGCGCTGGTTTTTCCTTTTTTCTCTATTTTTTTAGCATTTGTGGGACAAGA
ATGGATGATGGATCATATTGTAACAGTGTATTTAGTACTCTTAAGTTTATTAGTTATGTTGATTGTTAGTCGCTTGGAA
GAGAAATTTAAGAAAGGATAA
4188.5
ATGGGCAAAGGAGAGATGGGCAAAGGAGTTATTGGCTTGGAGTTCGACTCAGAAGTATTGGTCAACAAGGCTCCAACCC
TTCAATTGGCAAATGGTAAAACAGCGACTTTCCTAACCCAGTATGATAGCAAGACCTTGTTGTTTGCAGTAGATAAGGA
AGATATCGGACAGGAAATTATTGGTATAGCTAAAGGAAGCATCGAAAGTATGCATAATCTTCCTGTAAATCTAGCAGGT
GCCAGAGTTCCTGGCGGAGTAAATGGTAGCAAAGCAGCGGTGCATGAAGTTCCAGAATTTACAGGGGGAGTTAATGGTA
CAGACCCAGCTGTTCATGAAATCGCAGAGTATAAGGGATCTGATTCGCTTGTAACTCTTACTACAAAAAAAGATTATAC
TTACAAAGCTCCTCTTGCTCAGCAGGCACTTCCTGAAACAGGAAACAAGGAGAGTGACCTCCTAGCTTCACTAGGACTA
ACAGCTTTCTTCCTTGGTCTGTTTACGCTAGGGAAAAAGAGAGAACAATAA
4188.10.
ATGTTTAAAGTTTTACAAAAAGTTGGAAAAGCTTTATGTTACCTATAGCTATACTTCCTGCAGCAGGTCTACTTTTGGG
GATTGGTGGTGCACTTTCAAACCCAACCACGATAGCAACTTATCCAATACTAGACAATAGTATTTTTCAATCAATATTC
CAAGTAATGAGCTCTGCAGGAGAGGTTGTATTCAGTAATTTGTCACTACTTCTCTGTGTGGGATTATGTATTGGCTTAG
CGAAACGAGATAAAGGAACCGCTGCGTTAGCAGGAGTAACTGGTTACTTAGTTATGACTGCAACGATCAAAGCTTTGGT
AAAACTTTTTATGGCAGAAGGATCTGCAATTGATACTGGAGTTATTGGAGCATTAGTTGTCGGAATAGTTGCCGTATAT
TTGCACAACCGATATAACAATATTCAATTACCTTCCGCTTTAGGATTCTTTGGAGGTTCACGCTTCGTTCCTATTGTTA
CATCGTTCTCTCTATCTGATTGGCTTTGTCTTCTTTGTTATTTGGCCACCTTTCCAACAACTTCTTCTTGTTTCTACAG
GTGGATATATTTCTCAGGCGGGTCCAATTGGAACTTTTCTATATGGATTTTTAATGAGACTTTCTGGAGCAGTAGGCTT
ACATCATATAATTTACCCTATGTTTTGGTATACTGAACTTGGTGGTGTTGAAACTGTTGCAGGACAAACAGTGGTTGGA
GCTCAAAAAATATTTTTTGCTCAATTAGCCGATTTGGCCCATTCTGGATTATTTACAGAAGGAACAAGGTTTTTTGCAG
GTCGTTTCTCAACAATGATGTTCGGTTTACCGGCTGCCTGTTTAGCGATGTACCATAGTGTTCCTAAAAATCGTCGTAA
AAAATACGCGGGTTTGTTTTTTGGAGTTGCTTTAACATCTTTTATTACCGGTATTACAGAACCAATTGAATTTATGTTT
CTATTCGTCAGTCCGGTTCTATATGTTGTTCACGCATTCCTTGATGGTGTTAGCTCTTTATTGCAGACGTCTTAAATAT
TTCAATAGGAAACACATTTTCAGGAGGTGTAATCGATTTCACTTTATTTGGAATTTTGCAGGGGAACGCTAAGACGAAT
TGGGTTCTTCAGATTCCATTTGGACTTATTTGGAGTGTTTTGTATTATATTATTTTTAGATGGTTCATTACTCAATTCA
ACGTTCTAACGCCAGGGCGAGGAGAAGAAGTAGATTCTAAAGAAATTTCTGAATCCGCAGATTCAACTTCAAATACTGC
AGATTATTTAAAACAGGATAGCCTACAAATTATCAGAGCCTTGGGTGGATCAAATAATATAGAAGATGTAGATGCTTGT
GTGACACGTTTACGTGTAGCTGTAAAAGAAGTTAATCAAGTTGATAAAGCACTTTTAAAACAAATTGGTGCAGTTGATG
TCTTAGAAGTGAAGGGTGGCATTCAAGCAATCTATGGAGCAAAAGCAATCTTATATAAAAATAGTATTAATGAAATTTT
AGGTGTAGATGATTAA
4188.11
ATGAAATAGAAAATTAGCTTGTACAGTACTTGCGGGTGCTGCGGTTCTTGGTCTTGCTGCTTGTGGCAATTCTGGCGGA
AGTAAAGATGCTGCCAATCAGCTGGTGACGGTGCCAAAACAGAAATCACTTGGTGGGCATTCCCAGTATTTACCCAAGA
AAAAACTGGTGACGGTGTGGAACTTATGAAAAATCAATCATCGAAGCGTTTGAAAAAGCAAACCCAGATATAAAAGTGA
AATTGGAAACCATCGACTTCAAGTCAGGTCCTGAAAAAATCACAACAGCCATCGAAGCAGGAACAGCTCCAGACGTACT
CTTTGATGCACCAGGACGTATCATCCAATACGGTAAAAACGGTAATTGGCTGAGTTGAATGACCTCTTCACAGATGAAT
TTGTTAAAGATGTCAACAATGAAAACATCGTACAAGCAAGTAAAGCTGGAGACAAGGCTTATATGTATCCGATAGTTCT
GCCCCATTCTACATGGCAATGAACAAGAAAATGTTAGAAGATGCTGGAGTAGCAAACCTTGTAAAAGAAGGTTGGACAA
CTGATGATTTTGAAAAAGTATTGAAAGCACTTAAAGACAAGGGTTACACACCAGGTTCATTGTTCAGTTCTGGTCAAGG
GGGAGACCAAGGAACACGTGCCTTTATCTCTAACCTTTATAGCGGTTCTGTAACAGATGAAAAAGTTAGCAAATATACA
ACTGATGATCCTAAATTCGTCAAAGGTCTTGAAAAAGCAACTAGCTGGATTAAAGACAATTTGATCAATAATGGTTCAC
AATTTGACGGTGGGGCAGATATCCAAAACTTTGCCAACGGTCAAACATCTTACACAATCCTTTGGGCACCAGCTCAAAA
TGGTATCCAAGCTAAACTTTTAGAAGCAAGTAAGGTAGAAGTGGTAGAAGTACCATTCCCATCAGACGAAGGTAAGCCA
GCTCTTGAGTACCTTGTAAACGGGTTTGCAGTATTCAACAATAAAGACGACAAGAAAGTCGCTGCATCTAAGAAATTCA
TCCAGTTTATCGCAGATGACAAGGAGTGGGGACCTAAAGACGTAGTTCGTACAGGTGCTTTCCCAGTCCGTACTTCATT
TGGAAAACTTTATGAAGACAAACGCATGGAAACAATCAGCGGCTGGACTCAATACTACTCACCATACTACAACACTATT
GATGGATTTGCTGAAATGAGAACACTTTGGTTCCCAATGTTGCAATCTGTATCAAATGGTGACGAAAAACCAGCAGATG
CTTTGAAAGCCTTCACTGAAAAAGCGAACGAAACAATCAAAAAAGCTATGAAACAATAG
4188.12
ATGCAATCTACAGAAAAAAAACCATTAACAGCCTTTACTGTTATTTCAACAATCATTTTGCTCTTGTTGACTGTGCTGT
TCATCTTTCCATTCTACTGGATTTTGACAGGGGCATTCAAATCACAACCTGATACAATTGTTATTCCTCCTCAGTGGTT
CCCTAAAATGCCAACCATGGAAAACTTCCAACAACTCATGGTGCAGAACCCTGCCTTGCAATGGATGTGGAACTCACTA
TTTATCTCATGGTAACCATGTTCTTAGTTTGTGCAACCTCATCTCTAGCAGGTTATGTATTGGCTAAAAAACGTTTCTA
TGGTCAACGCATTCTATTTGCTATCTTTATCGCTGCTATGGCGCTTCCAAAACAAGTTGTCCTTGTACCATTGGTACGT
ATCGTCAACTTCATGGGAATCCATGATACTCTCTGGGCAGTTATCTTGCCTTTGATTGGATGGCCATTCGGTGTCTTCC
TCATGAAACAGTTCAGTGAAAATATCCCTACAGAGTTGCTTGAATCAGCTAAAATCGACGGTTGTGGTGAGATTCGTAC
CTTCTGGAGTGTAGCCTTCCCGATTGTGAAACCAGGGTTTGCAGCCCTTGCAATCTTTACCTTCATCAATACTTGGAAT
GACTACTTCATGCAATTGGTAATGTTGACTTCACGTAACAATTTGACCATCTCACTTGGGGTTGCGACCATGCAGGCTG
AAATGGCAACCAACTATGGTTTGATTATGGCAGGAGCTGCCCTTGCTGCTGTTCCAATCGTCACAGTCTCCTAGTCTTC
CAAAAATCCTTCACACAGGGTATTACTATGGGAGCGGTCAAAGGATAA
4191.1
ATGAAAAAAACTTTTTTCTTACTGGTGTTAGGCTTGTTTTGCCTTCTTCCACTCTCTGTTTTTGCCATTGATTTCAAGA
TAAACTCTTATCAAGGGGATTTGTATATTCATGCAGACAATACGGCAGAGTTTAGACAGAAGATAGTTTACCAGTTTGA
GGAGGACTTTAAGGGCCAATCGTGGGACTTGGACGTGCTGGTAAGATGCCTAGCGGGTTTGACATTGACCCTCATCCAA
AGATTCAGGCCGCGAAAAACGGTGCAGAACTAGCAGATGTGACTAGCGAAGTAACAGAAGAAGCGGATGGTTATACTGT
GAGAGTCTATAATCCAGGTCAGGAGGGCGACATAGTTGAAGTTGACCTCGTCTGGAACTTAAAAAATTTACTTTTCCTT
TATGATGATATCGCTGAATTAAATTGGCAACCTCTGACAGATAGTTCAGAGTCTATTGAAAAGTTTGAATTTCATGTAA
GGGGAGACAAGGGGGCTGAAAAACTCTTTTTCCATACAGGGAAACTTTTTAGAGAGGGAACGATTGAAAAGAGTAACCT
TGATTATACTATCCGTTTAGACAATCTTCCGGCTAAGCGTGGAGTTGAGTTGCATGCCTATTGGCCTCGGACCGATTTT
GCTAGCGCTAGGGATCAGGGATTGAAAGGGAATCGTTTAGAAGAGTTTAATAAGATAGAAGACTCGATTGTTAGAGAAA
AAGATCAGAGTAAACAACTCGTTACTTGGGTCCTCCCTTCGATCCTTTCCATCTCCTTGTTATTGAGTGTCTGCTTCTA
TTTTATTTATAGAAGAAAGACCACTCCTTCAGTCAAATATGCCAAAAATCATCGTCTCTATGAACCACCAATGGAATTA
GAGCCTATGGTTTTATCAGAAGCAGTCTACTCGACCTCCTTGGAGGAAGTGAGTCCCTTGGTCAAGGGAGCTGGAAAAT
TCACCTTTGATCAACTTATTCAAGCTACCTTGCTAGATGTGATAGACCGTGGGAATGTCTCTATCATTTCAGAAGGAGA
TGCAGTTGGTTTGAGGCTAGTAAAAGAAGATGGTTTGTCAAGCTTTGAGAAAGACTGCCTAAATCTAGCTTTTTCAGGT
AAAAAAGAAGAAACTCTTTCCAATTTGTTTGCGGATTACAAGGTATCTGATAGTCTTTATCGTAGAGCCAAAGTTTCTG
ATGAAAAACGGATTCAAGCAAGAGGGCTTCAACTCAAATCTTCTTTTGAAGAGGTATTGAACCAGATGCAAGAAGGAGT
GAGAAAACGAGTTTCCTTCTGGGGGCTCCCAGATTATTATCGTCCTTTAACTGGTGGGGAAAAGGCCTTGCAAGTGGGT
ATGGGTGCCTTGACTATCCTGCCCCTATTTATCGGATTTGGTTTGTTCTTGTACAGTTTAGACGTTCATGGCTATCTTT
ACCTCCCTTTGCCAATACTTGGTTTTCTAGGGTTAGTTTTGTCTGTTTTCTATTATTGGAAGCTTCGACTAGATAATCG
TGATGGTGTTCTAAATGAAGCGGGAGCTGAGGTCTACTATCTCTGGACCAGTTTTGAAAAATATGTTGCGTGAGATTGC
ACGATTGGATCAGGCTGAACTGGAAAGTATTGTGGTCTGGAATCGCCTCTTGGTCTATGCGACCTTATTTGGCTATGCG
GACAAGGTTAGTCATTTGATGAAGGTTCATCAGATTCAAGTGGAAAATCCAGATATCAATCTCTATGTAGCTTATGGCT
GGCACAGTACGTTTTATCATTCAACAGCACAAATGAGCCATTATGCTAGTGTCGCAAATACAGCAAGCACCTACTCTGT
ATCTTCTGGAAGTGGAAGTTCTGGTGGTGGCTTCTCTGGAGGCGGAGGTGGCGGCAGTATCGGTGCCTTTTAA
4191.2
ATGAAAAAAGTAAGAAAGATATTTCAGAAGGCAGTTGCAGGACTGTGCTGTATATCTCAGTTGACAGCTTTTTCTTCGA
TAGTTGCTTTAGCAGAAACGCCTGAAACCAGTCCCAGCGATAGGAAAAGTAGTGATTAAGGAGACAGGCGAAGGAGGAG
CGCTTCTAGGAGATGCCGTCTTTGAGTTGAAAAACAATACGGATGGCACAACTGTTTCGCAAAGGACAGAGGCGCAAAC
AGGAGAAGCGATATTTTCAAACATAAAACCTGGGACATACACCTTGACAGAAGCCCAACCTCCAGTTGGTTATAAACCC
TCTACTAAACAATGGACTGTTGAAGTTGAGAAGAATGGTCGGACGACTGTCCAAGGTGAACAGGTAGAAAATCGAGAAG
AGGCTCTATCTGACCAGTATCCACAAACAGGGACTTATCCAGATGTTCAAACACCTTATCAGATTATTAAGTAGATGGT
TCGGAAAAAAACGGACAGCACAAGGCGTTGAATCCGAATCCATATGAACGTGTGATTCCAGAAGGTACACTTTCAAAGA
GAATTTATCAAGTGAATAATTTGGATGATAACCAATATGGAATCGAATTACGGTTAGTGGGAAAACAGTGTATGAACAA
AAAGATAAGTCTGTGCCGCTGGATGTCGTTATCTTGCTCGATAACTCAAATAGTATGAGTAACATTCGAAACAAGAATG
CTCGACGTGCGGAAAGAGCTGGTGAGGCGACACGTTCTCTTATTGATAAAATTACATCTGATTCAGAAAATAGGGTAGC
GCTTGTGACTTATGCTTCCACTATCTTTGATGGGACCGAGTTTACAGTAGAAAAAGGGGTAGCAGATAAAAACGGAAAG
CGATTGAATGATTCTCTTTTTTGGAATTATGATCAGACGAGTTTTACAACCAATACCAAAGATTATAGTTATTTAAAGC
TGACTAATGATAAGAATGACATTGTAGAATTAAAAAATAAGGTACCTACCGAGGCAGAAGACCATGATGGAAATAGATT
GATGTACCAATTCGGTGCCACTTTTACTCAGAAAGCTTTGATGAAGGCAGATGAGATTTTGACACAACAAGCGAGACAA
AATAGTCAAAAAGTCATTTTCCATATTACGGATGGTGTCCCAACTATGTCGTATCCGATTAATTTTAATCATGCTACGT
TTGCTCCATCATATCAAAATCAACTAAATGCATTTTTTAGTAAATCTCCTAATAAAGATGGAATACTATTAAGTGATTT
TATTACGCAAGCAACTAGTGGAGAACATACAATTGTACGCGGAGATGGGCAAAGTTACCAGATGTTTACAGATAAGACA
GTTTATGAAAAAGGTGCTCCTGCAGCTTTCCCAGTTAAACCTGAAAAATATTCTGAAATGAAGGCGGCTGGTTATGCAG
TTATAGGCGATCCAATTAATGGTGGATATATTTGGCTTAATTGGAGAGAGAGTATTCTGGCTTATCCGTTTAATTCTAA
TACTGCTAAAATTACCAATCATGGTGACCCTACAAGATGGTACTATAACGGGAATATTGCTCCTGATGGGTATGATGTC
TTTACGGTAGGTATTGGTATTAACGGAGATCCTGGTACGGATGAAGCAACGGCTACTAGTTTTATGCAAAGTATTTCTA
GTAAACCTGAAAACTATACCAATGTTACTGACACGACAAAAATATTGGAACAGTTGAATCGTTATTTCCACACCATCGT
AACTGAAAAGAAATCAATTGAGAATGGTACGATTACAGATCCGATGGGTGAGTTAATTGATTTGCAATTGGGCACAGAT
GGAAGATTTGATCCAGCAGATTACACTTTAACTGCAAACGATGGTAGTCGCTTGGAGAATGGACAAGCTGTAGGTGGTC
CACAAAATGATGGTGGTTTGTTAAAAAATGCAAAAGTGCTCTATGATACGACTGAGAAAAGGATTCGTGTAACAGGTCT
GTACCTTGGAACGGATGAAAAAGTTACGTTGACCTACAATGTTCGTTTGAATGATGAGTTTGTAAGCAATAAATTTTAT
GATACCAATGGTCGAACAACCTTACATCCTAAGGAAGTAGAACAGAACACAGTGCGCGACTTCCCGATTCCTAAGATTC
GTGATGTGCGGAAGTATCCAGAAATCACAATTTCAAAAGAGAAAAAACTTGGTGACATTGAGTTTATTAAGGTCAATAA
AAATGATAAAAAACCACTGAGAGGTGCGGTCTTTAGTCTTCAAAAACAACATCCGGATTATCCAGATATTTATGGAGCT
ATTGATCAAAATGGCACTTATCAAAATGTGAGAACAGGTGAAGATGGTAAGTTGACCTTTAAAAATCTGTCAGATGGGA
AATATCGATTATTTGAAAATTCTGAACCAGCTGGTTATAAACCCGTTCAAAATAAGCCTATCGTTGCCTTCCAAATAGT
AAATGGAGAAGTCAGAGATGTGACTTCAATCGTTCCACAAGATATACCAGCGGGTTACGAGTTTACGAATGATAAGCAC
TATATTACCAATGAACCTATTCCTCCAAAGAGAGAATATCCTCGAACTGGTGGTATCGGAATGTTGCCATTCTATCTGA
TAGGTTGCATGATGATGGGAGGAGTTCTATTATACACACGGAAACATCCGTAA
4191.3
ATGAAATCAATCAACAAATTTTAACAATGCTTGCTGCCTTATTACTGACAGCGAGTAGCCTGTTTTCAGCTGCAACAGT
TTTTGCGGCTGGGACGACAACAACATCTGTTACCGTTCATAAACTATTGGCAACAGATGGGGATATGGATAAAATTGCA
AATGAGTTAGAAACAGGTAACTATGCTGGTAATAAAGTGGGTGTTCTACCTGCAAATGCAAAAGAAATTGCCGGTGTAT
GTTCGTTTGGACAAATACTAATAATGAAATTATTGATGAAAATGGCCAAACTCTAGGAGTGAATATTGATCCACAAACA
TTTAAACTCTCAGGGGCAATGCCGGCAACTGCAATGAAAAAATTAACAGAAGCTGAAGGAGCTAAATTTAACACGGCAA
TTTACCAGCTGCTAAGTATAAAATTTATGAAATTCACAGTTTATCAACTTATGTCGGTGAAGATGGAGCAACCTTAACA
GGTTCTAAAGCAGTTCCAATTGAAATTGAATTACCATTGAACGATGTTGTGGATGCGCATGTGTATCCAAAAAATACAG
AAGCAAAGCCAAAAATTGATAAAGATTTCAAAGGTAAAGCAAATCCAGATACACCACGTGTAGATAAAGATACACCTGT
GAACCACCAAGTTGGAGATGTTGTAGAGTACGAAATTGTTACAAAAATTCCAGCACTTGCTAATTATGCAACAGCAAAC
TGGAGCGATAGAATGACTGAAGGTTTGGCATTCAACAAAGGTACAGTGAAAGTAACTGTTGATGATGTTGCACTTGAAG
CAGGTGATTATGCTCTAACAGAAGTAGCAACTGGTTTTGATTTGAAATTAACAGATGCTGGTTTAGCTAAAGTGAATGA
CCAAAACGCTGAAAAAACTGTGAAAATCACTTATTCGGCAACATTGAATGACAAAGCAATTGTAGAAGTACCAGAATCT
AATGATGTAACATTTAACTATGGTAATAATCCAGATCACGGGAATACTCCAAAGCCGAATAAGCCAAATGAAAACGGCG
ATTTGACATTGACCAAGACATGGGTTGATGCTACAGGTGCACCAATTCCGGCTGGAGCTGAAGCAACGTTCGATTTGGT
TAATGCTCAGACTGGTAAAGTTGTACAAACTGTAACTTTGACAACAGACAAAAATACAGTTACTGTTAACGGATTGGAT
AAAAATACAGAATATAAATTCGTTGAACGTAGTATAAAAGGGTATTCAGCAGATTATCAAGAAATCACTACAGCTGGAG
AAATTGCTGTCAAGAACTGGAAAGACGAAAATCCAAAACCACTTGATCCAACAGAGCCAAAAGTTGTTACATATGGTAA
AAAGTTTGTCAAAGTTAATGATAAGATAATCGTTTAGCTGGGGCAGAATTTGTAATTGCAAATGCTGATAATGCTGGTC
AATATTTAGCACGTAAAGCAGATAAAGTGAGTCAAGAAGAGAAGCAGTTGGTTGTTACAACAAAGGATGCTTTAGATAG
AGCAGTTGCTGCTTATAACGCTCTTACTGCACAACAACAAACTCAGCAAGAAAAAGAGAAAGTTGACAAAGCTCAAGCT
GCTTATAATGCTGCTGTGATTGCTGCCAACAATGCATTTGAATGGGTGGCAGATAAGGACAATGAAAATGTTGTGAAAT
TAGTTTCTGATGCACAAGGTCGCTTTGAAATTACAGGCCTTCTTGCAGGTACATATTACTTAGAAGAAACAAAACAGCC
TGCTGGTTATGCATTACTAACTAGCCGTCAGAAATTTGAAGTCACTGCAACTTCTTATTCAGCGACTGGACAAGGCATT
GAGTATACTGCTGGTTCAGGTAAAGATGACGCTACAAAAGTAGTCAACAAAAAAATCACTATCCCACAAACGGGTGGTA
TTGGTACAATTATCTTTGCTGTAGCGGGGGCTGCGATTATGGGTATTGCAGTGTACGCATATGTTAAAAACAACAAAGA
TGAGGATCAACTTGCTTAA
4191.4
ATGACAATGCAGAAAATGCAGAAAATGATTAGTCGTATCTTCTTTGTTATGGCTCTGTGTTTTTCTCTTGTATGGGGTG
CACATGCAGTCCAAGCGCAAGAAGATCACACGTTGGTCTTGCAATTGGAGAACTATCAGGAGGTGGTTAGTCAATTGCC
ATCTCGTGATGGTCATCGGTTGCAAGTATGGAAGTTGGATGATTCGTATTCCTATGATGATCGGGTGCAAATTGTAAGA
GACTTGCATTCGTGGGATGAGAATAAACTTTCTTCTTTCAAAAAGACTTCGTTTGAGATGACCTTCCTTGAGAATCAGA
TTGAAGTATCTCATATTCCAAATGGTCTTTACTATGTTCGCTCTATTATCCAGACGGATGCGGTTTCTTATCCAGCTGA
ATTTCTTTTTGAAATGACAGATCAAACGGTAGAGCCTTTGGTCATTGTAGCGAAAAAAACAGATACAATGACAACAAAG
GTGAAGCTGATAAAGGTGGATCAAGACCACAATCGCTTGGAGGGTGTCGGCTTTAAATTGGTATCAGTAGCAAGAGATG
TTCTGAAAAAGAGGTTCCCTGATTGGAGAATACCGTTACAGTTTCTTCTGGTCAAGTAGGGAGAACTCTCTATACTGAT
AAAAATGGAGAGATTTTGTGACAAATCTTCCTCTTGGGAACTATCGTTTCAAGGAGGTGGAGCCACTGGCAGGCTATGC
TGTTACGACGCTGGATACGGATGTCCAGCTGGTAGATCATCAGCTGGTGACGATTACGGTTGTCAATCAGAAATTACCA
CGTGGCAATGTTGACTTTATGAAGGTGGATGGTCGGACCAATACCTCTCTTCAAGGGGCAATGTTCAAAGTCATGAAAG
AAGAAAGCGGACACTATACTCCTGTTCTTCAAAATGGTAAGGAAGTAGTTGTAACATCAGGGAAAGATGGTCGTTTCCG
AGTGGAAGGTCTAGAGTATGGGACATACTATTTATGGGAGCTCCAAGCTCCAACTGGTTATGTTCAATTAACATCGCCT
GTTTCCTTTACAATCGGGAAAGATACTCGTAAGGAACTGGTAACAGTGGTTAAAAATAACAAGCGACCACGGATTGATG
TGCCAGATACAGGGGAAGAAACCCTTGTATATCTTGATGCTTGTTGCCATTTTGTTGTTTGGTAG
4191.5
ATGAGCCACATATACTTATCTATTTTCACAAGTCTCTTGCTGATGCTAGGACTTGTCAATGTTGCTCAAGCCGATGAAT
ATTTACGCATCGGTATGGAAGCAGCATATGCTCCCTTTAACTGGACCCAGGATGATGATAGCAACGGAGCTGTCAAAAT
CGATGGGACCAATCAGTATGCCAACGGATACGATGTTCAAATCGCCAAGAAAATCGCTAAGGACTTAGGTAAAGAACCT
TTGGTTGTTAAAACCAAGTGGGAAGGTCTAGTCCCTGCCCTTACTTCTGGTAAGATTGACATGATTATCGCAGGTATGA
GTCCAACTGCAGAACGCAAACAAGAAATTGCCTTTTCGAGCAGTTACTATACTAGCGAACCAGTTTTGCTTGTCAAAAA
AGATTCTGCCTACGCAAGTGCTAAATCTTTGGATGACTTTAACGGTGCAAAAATCACTTCTCAACAAGGGGTCTACCTT
TATAACTTGATTGCACAAATCCCAGGTGCTAAAAAAGAAACAGCCATGGGAGACTTCGCTCAAATGCGACAAGCTCTTG
AGGCTGGTGTCATTGATGCTTATGTTTCTGAACGTCCAGAAGCACTGACTGCTGAAGCTGCGAACTCTAAGTTCAAGAT
GATTCAAGTAGAACCTGGTTTCAAAACTGGGGAAGAAGATACAGCTATCGCTATCGGGCTTCGTAAAAATGACAATCGT
ATTAGCCAAATCAATGCCAGCATTGAAACCATTTCAAAAGATGACCAAGTTGCCTTGATGGATCGTATGATCAAGGAAC
AACCTGCCGAAGCTACAACAACTGAAGAGACTAGCAGTAGTTTCTTTAGCCAAGTTGCTAAAATTCTTTCTGAAAACTG
GCAACAACTCTTGCGTGGTGCTGGTATCACTCTTTTAATCTCTATCGTCGGAACCATCATAGGTCTCATTATTGGACTT
GCCATTGGTGTCTTCCGTACTGCTCCTCTCTCTGAAAACAAGTCATTTACGGCCTACAAAAACTAGTCGCTGGGTTCTC
AATCTCTACATTGAAATTTTCCGTGGTACGCCAATGATTGTTCAATCGATGGTTATCTACTATGGAACTGCCCAAGCTT
TCGGGATCAACCTTGACCGTACACTGGCTGCTATCTTCATCGTTTCAATCAATACCGGTGCCTACATGACTGAAATGCT
CCGTGGTGGTATCCTAGCAGTTGACAAGGGACAATTTGAAGCTGCGACTGCTCTTGGTATGACCCATAACCAGACCATG
CGTAAGATTGTCCTACCTCAGGTAGTCCGTAACATCCTACCTGCAACTGGTAAGAATTTGTCATCAATATCAAAGATAC
ATCTGTATTGAACGTTATCTCTGTTGTCGAACTTTATTTCTCAGGAAATACCGTGGCAACACAAACCTATCAATACTTC
CAGACATTTACAATCATCGCCGTGATTTACTTTGTCCTCACCTTCACCGTAACACGTATCCTACGCTTTATCGAGCGCA
GAATGGACATGGATACCTACACTACAGGTGCTAACCAAATGCAAACGGAGGATTTGAAATAA
4191.6
ATGACACAAGCAATCCTTGAAATTAAACACCTCAAAAAATCCTATGGACAAAACGAAGTGCTAAAAGACATTTCACTCA
CTGTCCACAAGGGAGAGGTCATCTCTATCATCGGAAGCTCTGGAAGCGGAAAATCGACCTTCCTACGCTCCATTAACCT
ACTTGAAACACCAACTGATGGACAAATCCTTTATCATGGACAAAACGTCCTCGAAAAAGGCTATGACCTCACGCAATAC
CGTGAAAGTTGGGGATGGTTTTCCAATCCTTTAACCTCTTTGAAAATCTCAATGTTCTTGAAAACACAATCGTCGCTCA
GACAACTGTCCTAAAACGCGAACGCACAGAAGCTGAAAAGATTGCCAAAGAAAACCTGGAAAAGGTCGGCATGGGAGAA
CGCTACTGGCAAGCCAAACCAAAACAACTCTCAGGTGGTCAAAAACAACGTGTGGCCATCGCTCGTGCCCTCTCCATGA
ATCCGGACGCTATTCTCTTTGATGAACCAACATCAGCTCTCGATCCAGAAATGGTTGGAGAAGTCCTCAAAATCATGCA
GGACCTGGCTCAGGAAGGCTTGACCATGATTGTCGTAACCCATGAAATGGAATTTGCCCGTGATGTCTCTCACCGTGTT
ATCTTTATGGATAAGGGCGTGATCGCTGAAGAAGGTAAACCAGAAGACCTCTTCACCAATCCTAAAGAAGACCGAACAA
AAGAGTTCCTTCAACGCTATCTCAAATAA
4192.3
ATGAAAAAGTATCAACTTCTATTCAAAATAAGTGCAGTCTTCTCTTACTTATTTTTCGTATTTAGTCTTTCTCAGCTGA
CGCTTATCGTCCAAAACTATTGGCAATTTTCTTCTCAGATAGGCAATTTATTCTGGATTCAAAATATCTTGAGTTTACT
TTTTATTGGAGTCATGATTGTGGTTCTTGTTAAGACAGGCATGGTATCTCTTCCGCATTCCAAGAAAAAATGGCTTTGG
TATTCGATTTTGACAGTATTAGTGCTAGTGTTCCAGATCTCTTTTAACGTTCAGACAGTAAACATGTTCAGTCAACTGC
GGAAGGTTGGGCTGTATTGATTGGTTATAGTGGGACTAACTTTGCAGAGCTAGGTATTTATATAGCCCTGTTCTTTCTG
GTTCCACTGATGGAAGAATTGATTTATAGAGGATTACTGCAACATGCTTTCTTTAAGCATTCGCGATTTGGTCTTGATT
TGCTTCTTCCTTCTATTTTATTTGCTCTCCCTCATTTTTCAAGCCTGCCTAGTCTGTTAGATATCTTCGTCTTTGCAAC
AGTTGGAATCATCTTTGCTGGTTTGACCCGCTATACCAAGAGCATTTATCCATCCTATGCGGTGCATGTGATCAATAAT
ATTGTAGCGACCTTCCCGTTTTTGCTCACTTTTCTACATAGGGTCTTGGGGTAA
4193.1
ATGAACAAGAACAATGGCTAGGTCTTGGCCTAGTTGCAGTGGCAGCAGTTGGACTTGCTGCATGTGGTAACCGCTCTTC
TCGTAACGCAGCTTCATCTTCTGATGTGAAGACAAAAGCAGCAATCGTCACTGATACTGGTGGTGTTGATGACAAATCA
TTCAACCAATCAGCTTGGGAAGGTTTGCAGGCTTGGGGTAAAGAACACAATCTTTCAAAAGATAACGGTTTCACTTACT
TCCAATCAACAAGTGAAGCTGACTACGCTAACAACTTGCAACAAGCGGCTGGAAGTTACAACCTAATCTTCGGTGTTGG
TTTTGCCCTTAATAATGCAGTTAAAGATGCAGCAAAAGAACACACTGACTTGAACTATGTCTTGATTGATGATGTGATT
AAAGACCAAAAGAATGTTGCGAGCGTAACTTTCGCTGATAATGAGTCAGGTTACTTGCAGGTGTGGCTGCAGCAAAAAC
AACTAAGACAAAACAAGTTGGTTTTGTAGGTGGTATCGAATCTGAAGTTATCTCTCGTTTTGAAGCAGGATTCAAGGCT
GGTGTTGCGTCAGTAGACCCATCTATCAAAGTCCAAGTTGACTACGCTGGTTCATTTGGTGATGCGGCTAAAGGTAAAA
CAATTGCAGCCGCACAATACGCAGCCGGTGCAGATATTGTTTACCAAGTAGCTGGTGGTACAGGTGCAGGTGTCTTTGC
AGAGGCAAAATCTCTCAACGAAAGCCGTCCTGAAAATGAAAAAGTTTGGGTTATCGGTGTTGATCGTGACCAAGAAGCA
GAAGGTAAATACACTTCTAAAGATGGCAAAGAATCAAACTTTGTTCTTGTATCTACTTTGAAACAAGTTGGTACAACTG
TAAAAGATATTTCTAACAAGGCAGAAAGAGGAGAATTCCCTGGCGGTCAAGTGATCGTTTACTCATTGAAGGATAAAGG
GGTGACTTGGCAGTAACAAACCTTTCAGAAGAAGGTAAAAAAGCTCTTCGAAGATGCAAAAGCTAAAATCCTTGATGGA
AGCGTAAAAGTTCCTGAAAAATAA
4193.3
ATGTCTAAAAAATTACAACAAATTTCGGTTCCCTTGATTTCTGTATTCCTAGGAATTTTACTCGGAGCCATTGTCATGT
GGATCTCGGTTATGATGCTATTTGGGGCTACGAAGAATTGTTCTATACAGCCTTTGGCAGTCTGCGTGGGATTGGAGAA
ATCTTCCGTGCTATGGGTCCTCTGGTCTGATTGGTCTTGGTTTTGCCGTTGCCAGTCGAGCTGGTTTCTTTAACGTCGG
ACTTCCTGGTCAGGCTTTGGCAGGTTGGATTCTCAGTGGTTGGTTTGCCCTGTTCGCATCCAGATATGCCCCGTCCCTT
GATGATTCTAGCAACCATCGTGATTGCCTGATTGCTGGTGGGATTGTCGGAGCGATTCCAGGTATTCTTAGGGCCTATC
TAGGGACGTCAGAGGTTATTGTAACCATCATGATGAACTACATTGTCTTGTATGTAGGGAATGCCTTTATCCATGCTTT
CCCTAAAGACTTCATGCAAAGTACAGATTCGACCATTCGTGTTGGGGCTAATGCAACCTATCAGACACCTTGGTTGGCT
GAGTTGACTGGTAACTCACGGATGAATATTGGTATTTTCTTTGCCATCATTGCCGTTGCAGTTATTGGTTCATGCTCAA
GAAACAACTCTGGTTTTGAAATCCGTGCAGTTGGTCTTAATCCACATGCTTCAGAATATGCTGGTATTTCTGCCAAGCG
GACTATTAATCCTATCTATGATTATTTCAGGTGCCTTGGCAGGTCTTGGTGGAGCTGTTGAAGGTTTGGGAACCTCCAG
AACGTCTATGTTCAAGGTTCGTCATTAGCTATCGGATTTAACGGAATGGCGGTTAGTTGCTGCGGCCAACTCACCAATT
GGTATACTCTGCAGCCTCCTATTTGGCGTTCTCCAAGTTGGGGCTCCTGGTATGAATGCGGCGCAGGTACCATCTGAGC
TTGTCAGCATTGTAACAGCGTCTATTATCTTCTTTGTCAGTGTTCATTACCTTATCGAACGCTTTTGTCAAACCGAAAA
AACAAGTTAAACGAGGTAAGTAA
4194.1
ATGGGAGTGAAAAAGAAACTAAAGTTGACTAGTTTTGCTAGGACTGTCTCTGTTAATCATGACAGCCTGTGCGACTAAT
GGGGTAACTAGCGATATTACAGCCGAATCGGCTGATTTTTGGAGTAAATTGGTTTACTTCTTTGCGGAAATCATTCGCT
TTTTATCGTTTGATATTAGTATCGGAGTGGGGATTATTCTCTTTACGGTCTTGATTCGTACAGTCCTCTTGCCAGTCTT
TCAGGTGCAAATGGTGGCTTCTAGGAAAATGCAGGAAGCTCAGCCACGCATTAAGGCGCTTCGAGAACAATATCCAGGT
CGAGATATGGAAAGCAGAACCAAACTAGAGCAGGAAATGCGTAAAGTATTTAAAGAAATGGGTGTCAGACAGTCAGACT
CTCTTTGGCCGATTTTGATTCAGATGCCGGTTATTTTGGCCCTGTTCCAAGCCCTATCAAGAGTTGACTTTTTAAAGAC
AGGTCATTTCTTATGGATTAACCTTGGTAGTGTGGATACAACCCTTGTTCTTCCGATTTTAGCAGCAGTATTCACCTTT
TTAAGTACTTGGTTGTCCAACAAAGCTTTGTCTGAGCGAAATGGCGCTACGACTGCGATGATGTATGGGATTCCAGTCT
TGATTTTTATCTTTGCAGTTTATGCGCCAGGTGGAGTCGCCCTATACTGGACAGTGTCTAATGCTTATCAAGTCTTGCA
AACCTATTTCTTGAATAATCCATTCAAGATTATCGCAGAGCGCGAGGCCGTAGTACAGGCACAAAAAGATTTGGAAAAT
AGAAAAAGAAAGCCAAGAAAAAGGCTCAGAAAACGAAATAA
4194.4
ATGGTTATCGATCCATTTGCTATCAACGAACTAGACTATTACTTAGTTTCACACTTCCACAGTGATCATATCGACCCAT
ACACAGCTGCAGCAATTCTCAATAATCCTAAGTTAGAGCATGTTAAGTTTATCGGTCCTTACCACTGTGGACGAATCTG
GGAAGGATGGGGTGTTCCAAAAGAACGTATCATCGTTGTTAAACCAGGTGACACTATCGAATTAAAAGATATGAAGATT
CATGCAGTAGAATCATTTGACCGTACTTGCTTGGTAACTCTCCCAGTGAACGGTGCTGATGAGACAGGCGGTGAACTTG
CTGGCTTGGCTGTTACAGATGAAGAAATGGCTCAAAAGGCTGTTAACTATATCTTTGAAACACCAGGTGGAACCATCTA
TCATGGTGCAGATTCTCACTTCTCAAACTATTTTGCAAAACATGGTAAAGACTTTAAAATTGATGTTGCTTTGAATAAC
TATGGTGAAAATCCGGTAGGTATCCAAGACAAAATGACATCTATCGACCTTCTTCGTATGGCAGAAAATCTGCGTACCA
AGTCATTATCCCAGTTCACTATGATATCTGGTCTAACTTCATGGCTTCTACTAATGAGATTCTAGAACTTTGGAAAATG
CGAAAAGATCGCTTGCAATACGATTTCCATCCATTTATCTGGGAAGTTGGCGGTAAGTACACTTATCCTCAAGATCAAC
ACTTAGTAGAATACCATCATCCACGTGGTTTTGATGATTGTTTTGAACAAGACTCTAACATTCAATTTAAAGCTTTGCT
ATAA
4196.2
ATGTTCCTTTCAGGCTGGTTGTCTAGTTTTGCTAATACTTATATCCATGATTTACTGGGGGTTCTTTTCCCAGATAGTC
CATTTTTAAATGCCTTTGAAAGTGCTATTGCGGCTCCTTTGGTAGAAGAACCCTTGAAATTATTGTCACTTGTTTTGTT
TTGGCTTTGATTCCTGTGCGAAAATTAAAATCTTTGTTTTTACTTGGAATTGCTTCCGGTTTGGGATTCCAAGTATCAT
CTCAGGAATTGCCTCTCACTGGACTTTTTCAGGTCTAGCTGTAGTAGGTGTTTACTTGCTTTACAGAGCCTATAAAGGA
CAGAAGGTTGGCAAGAAACAGGGCCTTATTTTTCTAGGTTTAGCCTTGGGAACTCACTTCTTGTTTAACTCTCCTTTTG
TGGAGTTGGAAACAGAGTTGCCTTTAGCGATTCCAGTGGTTACGGCTATTGCTCTCTATGGTTTTTATCATGCTTATTG
CTTTGTTGAGAAACACAATGAGTTGATGACCTAG
4197.1
ATGAAGGTGGAACCACGTTGCGACGTCCTTTCGAGGATGTCGCATTTTTTTATTAGGATACTAATTATGGAGTTGCAAG
AATTAGTGGAGCGCAGTTGGGCAATCCGACAAGCTTATCACGAACTGGAAGTTAAGCATCATGATTCCAAGTGGACGGT
AGAAGAAGACCTCTTGGCTTTATCTAATGATATTGGAAATTTCCAACGACTGGTGATGACAAAGCAAGGACGCTACTAT
GATGAAACACCCTACACACTGGAACAAAAACTTTCAGAAAATATCTGGTGGCTATTAGAACTTTCTCAACGTTTGGATA
TAGACATTCTGACGGAAATGGAAAACTTCCTCTCTGATAAAGAAAAGCAATTGAACGTTAGGACTTGGAAGTAG
4197.4
ATGCTTGATTGGAAACAATTTTTTTCTAGCCTATCGCGCTCCCGTAGTCGTCTTTTTATCTATCTGCTTTCTTTGGCAT
TTCTTGTCTTACTCTTTCAGTTTTTATTTGCCAGTCTAGGAATTTACTTCCTCTACTTTTTCTTCTTGTGTTGCTTTGT
AACCATATTATTTTTCACTTGGGACATATTGGTGGAAACGCAGGTCTATCGCCAGGAACTTCTCTATGGAGAGAGGGAA
GCCAAGTCTCCTTTGGAAATAGCTTTAGCAGAAAAATTAGAAGCGCGTGAGATGGAACTCTATCAGCAGAGGTCAAAAG
CAGAAAGAAAACTGACGGATTTGCTGGATTACTATACCTTGTGGGTCCATCAGATAAAGACCCCCATTGCAGCCAGTCA
ACTCTTAGTTGCAGAAGTGGTCGACCGCCAACTGAAGCAGCAGCTAGAACAGGAAATTTTCAAAATCGACTCCTATACC
AACCTAGTTTTACAGTACCTGCGTTTAGAAAGTTTCCATGATGATTTGGTCTTAAAGCAGGTTCAAATTGAGGACTTGG
TCAAGGAAATAATTCGTAAATATGCTCTTTTCTTTATTCAAAAAGGCCTTAAATGTCAATCTACATGACCTTGATAAAG
AAATCGTGACGGATAAAAAGTGGCTGCTAGTGGTTATTGAGCAAATCATCTCAAACAGTCTCAAGTACACCAAGGAAGG
TGGTCTGGAGATTTATATGGATGACCAAGAGCTTTGTATCAAAGATACGGGAATCGGGATAAAAAACAGTGATGTCCTC
CGAGTATTTGAACGTGGCTTTTCAGGATACAATGGCCGTTTGACCCAGCAGTCCTCTGGACTTGGCCTTTATCTATCTA
AGAAAATTTCTGAAGAACTGGGGCACCAGATTCGTATCGAGTCTGAGGTCGGAAAAGGAACGACAGTGCGGATTCAGTT
TGCTCAAGTGAACTTAGTCCTTGAGTAA
4211.2
ATGGAACTTTAATACACACAATGCTGAAATCTTGCTCAGTGCAGCTAATAAGTCCCACTATCCGCAGGATGAACTGCCA
GAGATTGCCCTAGCAGGGCGTTCAAATGTTTGGTAAATCCAGCTTTATCAACACTATGTTGAACCGTAAGAATCTCGCC
CGTACATCAGGAAAACCTGGTAAAACCCAGCTCCTGAACTTTTTTAACATTGATGACAAGATGCGCTTGTGGATGTGCC
TGGTTATGGCTATGCTCGTGTTTCTAAAAAGGAACGTGAAAAGTGGGGGTGCATGATTGAGGAGTACTTAACGACTCGG
GAAAATCTCCGTGCGGTTGTCAGTCTAGTTGACCTTCGTCATGACCCGTCAGCAGATGATGTGCAGATGTACGAATTTC
TCAAGTATTATGAGATTCCAGTCATCATTGTGGCGACCAAGGCGGACAAGATTCCTCGTGGTAAATGGAACAAGCATGA
ATCAGCAATCAAAAAGAAATTAAACTTTGACCCCAGTGACGATTTCATCCTCTTTTCATCTGTCAGTAAGGCAGGGATG
GATGAGGCTGGGATGCAATCTTAGAAAAATTGTGA
4211.3
ATGACAAAGAAACAACTTCACTTGGTGATTGTGACAGGGATGAGTGGCGCAGGGAAAACTGTAGCCATTCAGTCCTTCG
AGGATCTAGGTTATTTCACCATTGATAATATCCCGCCAGCTCTCTTGCCTAAGTTTTGCAGCTGGTTGAAATTAAGGAA
GACAATCCTAAGTTGGCCTTGGTAGTGGATATGCGTAGCCGTTCTTTCTTTTCAGAGATTCAAGCTGTTTTGGATGAGT
TGGAAAATCAAGATGGTTTGGATTTCAAAATCCTCTTTTTGGATGCGGCTGATAAGGAATTGGTCGCTCGTTACAAGGA
AACCAGACGGAGTCACCCACTAGCAGCAGACGGTCGTATTTTAGATGGAATCAAGTTGGAACGTGAACTCTTGGCACCT
TTGAAAAATATGAGCCAAAATGTGGTGGATACGACTGAACTCACTCCACGTGAGcTGCGCAAAACCCTGCAGAGCAGTT
TTCAGACCAAGAACAAGCCCAGTCTTTCCGTATCGAAGTCATGTCTTTTCGGATTTAAGTATGGAATCCCGATTGATGC
GGACTTGGTCTTTGATGTCCGTTTCTTGCCAAATCCCTATTATTTACCAGAACTGAGAAACCAAACGGGTGTGGATGAA
CCTGTTTATGATTATGTCATGAACCATCCTGAGTCAGAAGACTTTTATCAACATTTATTGGCCTTGATTGACCCGATTC
TGCCAAGTTACCAAAAGGAAGGTAAGTCCGTTTTTGACCATTGCCATGGGATGTACGGGTGGACAACACCGTAGTGTGG
CATTGCTAAACGCTTGGCGCAGGACTTATCCAAGAATTGGTCTGTTAATGAAGGGCATCGCGACAAAGACCGCAGAAAG
GAAACGGTAAACCGTTCATGA
4211.4
ATGAGAAAACCAAAGATAACGGTGATTGGTGGAGGGACTGGAAGTCCCGTCATTCTAAAAAGTCTGCGGGAAAAAGATG
TGGAAATCGCAGCTATCGTGACGGTGGCAGATGATGGTGGTTCTTCAGGTGAACTCCGAAAAAATATGCAACAGTTGAC
ACCGCCAGGTGATCTTCGTAATGTCCTTGTGGCCATGTCGGATATGCCTAAGTTTTATGAGAAGGTCTTTCAGTATCGG
TTCTCTGAGGATGCCGGAGCCTTTGCTGGCCATCCATTGGGAAATCTCATCATTGCTGGCTTGTCAGAAATGCAGGGTT
CAACCTATAATGCCATGCAGTTATTGAGCAAATTTTTCCATACAACAGGGAAAATTTATCCTTCCAGTGACCATCCTGA
CCCTTCATGCAGTCTTTTCAGGATGGGACAGAAGTGGCTGGAGAGAGTCATATTGTAGACCATCGAGGCATAATTGACA
ATGTCTATGTGACCAATGCCCTAAACGATGATACGCCTCTGGCCAGCCGTCGAGTAGTGCAGACCATCCTTGAAAGTGA
CATGATTGTCCTAGGGCCAGGTTCCCTCTTTACCTCTATTTTGCCCAATATCGTGATTAAGGAAATTGGGCGGGCTCTT
TTGGAAACCAAGGCAGAAATTGCCTATGTCTGCAATATCATGACCCAACGTGGGGAGACGGAACACTTTACAGATAGCG
ACCACGTGGAAGTCTTGCATCGTCACCTTGGTCGCCCTTTTATCGACACTGTCTTGGTGAATATTGAAAAAGTGCCTCA
GGAATACATGAATTCCAACCGTTTTGATGAATACTTAGTGCAAGTGGAACACGATTTTGTAGGTCTTTGTAAGCAAGTT
TCGCGCGTGATTTCATCTAACTTCCTTCGTCTGGAAAATGGCGGTGCCTTCCACGATGGAGATTTGATTGTGGACGAGT
TGATGCGCATTATACAGGTGAAAAAATGA
4213.1
ATGAAAAATTTGATAAAGTTGCTAATAATTAGATTGATTGTTAACTTAGCAGACACTGTATTTTATATAGTAGCATTGT
GGCACGTAGCAATAATTATTCTTCGAGCATGTTCTTAGGAATATTTATTGCAGTAAATTATCTACCGGATTTGTTACTA
ATCTTTTTTGGACCAGTTATTGACAGAGTAAATCCGCAAAAAATTCTTATAATATCAATTTTGGTTCAATTAGCAGTGG
CTGTAATATTTTTATTATTATTAAACCAAATATCATTTTGGGTGATAATGAGTCTAGTGTTTATTTCAGTAATGGCTAG
CTCCATAAGTTACGTGATAGAAGATGTGTTGATTCCTCAAGTGGTAGAATATGATAAGATTGTATTTGCAAATTCTCTT
TTTAGTATTTCGTATAAAGTATTAGATTCTATTTTTAATTCATTCGCATCATTTTTACAGGTGGCAGTAGGATTTATTT
TATTGGTTAAGATAGATATAGGCATATTTTTACTTGCTCTATTTATATTGTTGTTGTTAAAATTTAGAACTAGCAATGC
GAATATAGAAAACTTCTCTTTCAAATATTACAAGAGAGAAGTGTTGCAAGGTACAAAGTTTATTTTAAATAATAAATTA
TTATTTAAAACCAGTATTTCTTTAACGCTTATAAACTTTTTTTATTTCAGACAGTAGTTGTACCGATTTTTCTATTCGA
TATTTTGATGGTCCGATTTATGGTATTTTTTTAACTATTGCTGGTTTGGGTGGTATATTGGGAAATATGCTAGCGCCAA
TCGTAATAAAATATAAAATCGAATCAAATTGTTGGTGTATTTCTTTTTTTGAACGGCTCAAGTTGGTTAGTAGCAATTG
TTATAAAAGACTATACTTTATCACTATTATTTTTCGTTTGTTTTATGTCTAAAGGAGTCTTCAATATTATTTTAATTCG
TGTACCAACAATACCTCCACATCAACTTCTTGGTAGGGTAAATACTACCATTGATTCTATTATTCTTGGAATGCCAATT
GGTAGTTTAGTTGCAGGAACGCTTATTGATTGAATATTGAATTAGTGTTAATTGCTATTAGCATACCTTATTTTTTGTT
TTCTTATATTTTTTATACGGATAATGGATTGAAAGAATTTAGTATATATTAG
4213.2
ATGATGTCTAACAAAAATAAGGAAATTCTGATTTTTGCGATTCTCTATACAGTCCTCTTTATGTTTGATGGCGTTAAAT
TGCTGGCTCTTTAATGCCATCTGCCATTGCAAATTATCTGTTTATGTAGTTTTAGCTCTATATGGCTCCTTCTTGTTCA
AGGATAGATTGATCCAACAATGGAAGGAGATTAGAAAGACTAAAAGAAAATTCTTCTTTGGAGTCTTAACAGGATGGCT
CTCTCATTCTGATGACTGTTGTCTTTGAATTTGTATCAGAGATGTTGAAGCAGTTTGTGGGACTAGATGGACAAGGTCT
AAATCAGTCTAATATTCAAAGTACCTTTCAAGAACAACCACTACTGATAGCTGTTTTTGCTTTGTGTCATTGGACCTCT
GGTAGAAGAATTATTCCGTCAGGTCTTATTGCATTACTTGCAGGAACGGTTGTCAGGTTTACTAAGCATTATTCTGGTA
GGACTTGTTTTTGCTCTGACTCATATGCACAGTTTGGCTCTATCAGAGTGGATTGGTGCAGTTGGTTACTTAGGTGGAG
GCCTTGCCTTTTCTATTATTTATGTGAAAGAAAAAGAGAATATCTACTATCCCCTACTTGTTCACATGTTAAGCAACAG
CCTCTCCTTAATCATTTTAGCTATCAGTATAGTAAAATGA
4224.1
TTGAAAAAGCCAATTATCGAATTCAAAAACGTCTCTAAAGTTTTTGAAGACAGCAACACCAAGGTTCTCAAAGACATCA
ACTTTGAGTTGGAAGAAGGGAAATTCTACACCCTTCTAGGTGCATCTGGTTCGGGGAAATCAACTATCCTAAACATTAT
TGCAGGTTTACTGGATGCGACGACAGGAGATATCATGCTAGACGGTGTTCGTATCAATGATATTCCAACCAACAAGCGC
GACGTACATACCGTCTTCCAATCCTATGCCTTGTTCCCACATATGAATGTGTTTGAAAATGTTGCCTTTCCACTTCGCT
TGCGTAAAATTGATAAGAAAGAAATCGAGCAGCCTGTAGCGGAAGTTCTCAAGATGGTTCAGTTGGAAGGTTATGAAAA
ACGTTCCATCCGCAAACTTTCTGGAGGACAACGTCAGCGTGTGGCCATCGCCCGTGCTATCATCAACCAACCCCGTGTG
GTCTTGTTGGACGAGCCTTTATCAGCGCTGGACTTGAAATTGAGAACAGACATGCAGTACGAATTGCGTGAATTACAAC
AACGATTGGGCATTACCTGTCTTTGTCACTCACGATCAGGAAGAAGCTCTTGCCATGAGTGACTGGATTTTCGTTATGA
ATGATGGCGAGATTGTCCAGTCTGGAACCCCTGTGGACATCTACGATGAGCCAATCAACCACTTTGTTGCCACCTATCG
GGGAGTCAAACATCTTGCCAGGTACCATGATTGAGGACTACTTGGTCGAATTTAACGGCAAACGCTTTGAAGCGGTTGA
TGGTGGGATGAAGCCAAATGAACCTGTTGAGGTCGTTATTCGTCCAGAGGACTTGCGCATTACCCTTCCTGAAGAAGGC
AAGCTCCAAGTTAAGGTCGATACCCAGCTTTTCCGTGGAGTTCATTATGAAATTATCGCCTATGACGAACTTGGAAATG
AATGGATGATCCACTCAACCCGTAAGGCTATCGTGGGTGAGGAAATCGGTCTGGACTTTGAACCAGAAGACATCCACAT
CATGCGTCTCAATGAAACCGAAGAAGAGTTCGATGCTCGTATTGAGGAGTACGTAGAAATCGAAGAGCAAGAAGCAGGT
TTGATCAATGCAATCGAGGAGGAAAGAGATGAAGAAAACAAGCTCTAA
4252.1
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCA
TCTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGACTAAATTA
TCTTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTC
TAATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGA
CTTTTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGAT
TTTCTTGCTATGCTGGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGA
CCATTGTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGA
AGTTTCCTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
4252.2
ATGGTTAAAAAAATTATTGGAATGGTGCTAGCTTTACTTTCTGTAACTGTAGTAGGAGTAGGTGTTTTTGCTTATACTA
TTTATCAACAAGGGACAGAAACCTTAGCTAAAACCTATAAAAAAATCGGTGAAGAAACCAAGGTTATTGAAGCGACTGA
ACCTCTAACCATTCTGTTAATGGGAGTGGACACCGGAAATGTTGAACGAACTGAAACTTGGGTCGGTAGAAGTGATAGC
ATGATCTTGATGACAGTGAATCCTAAAACGAAAAAAACAACAATGATGAGTTTAGAGCGGGATATTCTGACGCGCATTG
AATCAGGGAATGGTCAGGTCATGAAGCGAAACTGAACTCAGCATATGCAGATGGTGGAGCAGAGCTTGCTATAGAAACC
ATTCAAAAAAATGATGAATATCCATATTGATCGCTATGTGATGGTCAATATGAGAGGATTGCAAAAACTAGTGGATGCA
GTAGGAGGTATTACAGTCAATAATATCCTAGGTTTCCCAATTTCTATCAGTGACCAAGAAGAATTTAATACTATTTCTA
TCGGTGTTGGGGAGCAACATATTGGGGGAGAAGAAGCCCTAGTCTATGCACGAATGCGTTACCAAGATCCTGAGGGGGA
TTATGGTCGTCAAAAACGTCAACGTGAAGTTATTCAAAAAGTCATGGAAAAAGCTCTCAGTTTAAATAGCATTGGTCAT
TATCAAGAGATTCTAAAAGCTTTGAGTGACAATATGCAGACCAATATTGATTGTCTGCAAAAAGTATCCCTAACTTGCT
AGGCTATAAAGATTCATTTAAAACCATTGAAACTCAGCAGTGCAGGGTGAAGGAGAGATACTTCAAGGTGTTTCTTACC
AGATTGTTTCGAGAGCACATATGTTGGAAATGCAAAATCTACTCCGACGTTCTTTGGGACAAGAAGAAGTTACTCAGCT
TGAAACCAATGCGGTTTATTTGAAGATTTATTTGGCAGAGCACCTGTTGGTGATGAAGATAATTAA
4256.2
ATGAAAAAACAAGCCTATGTCATTATTGCTCTCACCTCCTTCCTATTTGTCTTTTTTTTCTCCCACAGCTTGCTGGAAA
TACTTGATTTTGACTGGTCTATCTTTTTGCACGATGTCGAAAAAACAGAAAAATTTGTCTTTTTATTGTTGGTTTTCAG
CATGTCCATGACCTGTCTCTTAGCCCTGTTTTGGCGAGGGATCGAAGAGCTTTCTCTAAGAAAAATGCAGGCTAATCTC
AAGCGTTTATTAGCAGGGCAAGAAGTGGTTCAGGTTGCAGATCCAGATTTGGATGCCAGTTTCAAGTCCTTATCAGGTA
AACTTAACCTTTTGACAGAGGCTCTTCAAAAAGCTGAAAATCAGAGCCTTGCTCAGGAAGAGGAAATCATCGAGAAGGA
ACGGAAGCGAATTGCTCGGGATTTGCACGATACAGTCAGTCAGGAGTTGTTTGCGGCCCACATGATTTTATCGGGTATC
AGTCAGCAGGCTTTGAAATTGGATAGAGAAAAGATGCAGACCCAGTTGCAGAGTGTCACAGCTATTTTAGAAACAGCCC
AGAAGGATTTGCGGGTTTGCTCTTGCATTTGCGACCAGTTGAACTGGAGCAGAAGAGCTTGATAGAAGGGATTCAAATT
CTTTTAAAAGAGCTTGAGGACAAGAGTGATCTTAGGGTTAGTCTCAAGCAGAATATGACGAAATTGCCTAAGAAAATCG
AGGAGCATATCTTCCGTATCCTGCAAGAGTTGATTAGCAATACCCTCCGCCATGCCCAGGCATCTTGCCTAGATGTCTA
CCTCTATCAGACAGATGTTGAATTGCAACTGAAGGTGGTGGACAATGGGATTGGTTTCCAGTTAGGGAGCTTAGACGAC
TTGAGTTATGGACTGCGAAATATCAAGGAGCGGGTTGAAGATATGGCTGGAACAGTCAACTCTTGACAGCTCCCAAGCA
AGGGCTGGCGGTTGATATCCGTATTCCCCTGTTAGATAAGGAATGA
4263.1
ATGATTGTTTCCATTATTTCTCAAGGATTTGTCTGGGCTATTCTAGGTCTGGGAATCTTTATGACATTTAGGATTTTAA
ACTTTCCAGATATGACGACAGAAGGTTCCTTCCCTCTTGGGGGAGCTGTTGCTGTCACTTTGATAACCAAAGGCGTGAA
CCCATTTTTAGCGACACTTGTTGCTGTAGGAGCAGGTTGTTTGGCTGGAATGGCAGCAGGCCTTCTTTATACAAAAGGG
AAGATCCCAACCTTGCTCTCAGGGATTTTGGTGATGACTTCTTGTCACTCAATCATGCTCTTGATTATGGGACGTGCGA
ATTTAGGCCTGCTTGGAACCAAGCAAATTCAGGATGTTTTGCCTTTTGATTCGGATTTGAATCAACTCTTGACAGGTCT
CATCTTTGTGAGTATTGTTATTGCTCTCATGCTCTTTTTCTTGGACACTAAACTCGGACAAGCCTATATTGCTACAGGG
GATAATCCTGATATGGCTAGAAGTTTCGGGATTCATACTGGACGCATGGAGCTCATGGGCTTGGTCTTATCAAATGGTG
TGATTGCCCTTGCAGGTGCCCTCATTGCTCAGCAAGAAGGTTATGCCGATGTGTCTCGAGGGATCGGGGTTATCGTTGT
GGGGCTTGCAAGTTTGATTATTGGAGAAGTTATTTTCAAGAGTTTGAGCTTGGCAGAGCGTTTGGTTACTATCGTTGTA
GGTTCTATCGCTTATCAATTTTTAGTGTGGGCAGTTATCGCACTTGGCTTTAATACAAGTTACCTTCGTTTATACAGTG
CCTTGATTTTAGCAGTCTGCCTCATGATTCCAACATTTAAGCAAACAATCTTGAAAGGAGCCAAGTTAAGCAAATGA
4346.1
ATGAAAAAAATGAAAGTTTGGTCTACTGTACTTGCAACGGGAGTTGCTCTTACTACACTTGCTGCTTGCTCTGGAGGTT
CAAATTCTACGACTGCTTCTTCATCTGAAGAAAAAGCTGATAAAAGTCAAGAATTAGTTATCTATTCGAACTCAGTCTC
AAATGGTCGTGGTGATTGGTTAACTGCTAAAGCAAAAGAAGCTGGTTTTAATATAAAAATGGTTGATATCGCTGGCGCT
CAATTAGCAGACCGGTTATTGCTGAGAAGAATAATGCAGTTGCAGATATGGTATTTGGAATTGGTGCTGTTGATTCAAA
TAAAATTAGAGATCAAAAATTACTAGTACAGTACAAGCCTAAATGGTTAGATAAAATTGATCAATCTTTATCAGATAAA
GATAATTATTATAATCCTGTGATTGTTCAACCATTAGTTTTAATTGGGGCGCCTGATGTAAAAGAAATGCCTAAAGATT
GGACTGAATTAGGTAGTAAGTATAAAGGTAAATATTCAATTTCTGGTCTTCAAGGAGGTACAGGACGGGCAATTCTAGC
AAGTATCTAGTTCGATACCTGATGATAAAGGTGAATTAGGTGTTTCCGAAAAAGGTTGGGAAGTAGCAAAAGAATATTT
GAAAAATGCATACACTCTTCAAAAGGGAGAAAGTTCAATTGTTAAGATGTTAGACAAAGAAGATCCAATACAATATGGA
ATGATGTGGGGTTCTGGTGCATTAGTTGGACAAAAAGAACAAAATGTTGTTTTCAAAGTTATGACTCCTGAGATTGGTG
TACCATTTGTAACTGAACAAACTATGGTTTTAAGCACTAGTAAAAAACAAGCGTTAGCTAAAGAATTTATTGATTGGTT
TGGTCAATCAGAAATTCAAGTAGAATATAGTAAGAACTTTGGATCTATTCCTGCAAATAAAGATGCCCTCAAGATCTAC
CTGAAGATACGAAGAAATTTGTTGATCAAGTGAAACCACAAAATATTGACTGGGAAGCTGTTGGAAAGCATTTGGATGA
ATGGGTAGAAAAAGCTGAATTAGAATACGTACAATAA
4346.2
ATGATTAAATTTGATAATATTCAATTAAATATGGTGATTTTGTTGCAATTGATAATCTGAATTTAGATATACATGAAGG
GGAATTTTTTACATTTCTGGGCCTTCAGGATGTGGTAAATCAACTACTTTGAGAGCATTGGTAGGTTTTCTAGATCCAT
CATCAGGAAGTATTGAAGTTAATGGAACAGATGTCACTCATTTGGAACCTGAAAAGCGTGGAATTGGTATTGTATTCAA
TCTATGCGCTATTTCCAACTATGACTGTTTTTGATAATATTGCATTTGGTTTAAAAGTTAAGAAGGTAGCTCCAGATGT
TATTAAAGCTAAAGTATCAGCAGTGGCAGCAAAAATTAAGATCTCTGATCAACAGTTACAGCGTAATGTATCAGAATTA
TCTGGGGGTCAACAACAAAGGGTAGCATTGGCTCGTGCTCTGGTTCTTGAACCTAAAATTCTTTGTCTAGATGAACCAT
TGTCAAACCTGACGCAAAATTACGTGTAGATTTGAGAAAAAGAGTTGAAAAGACTTCAAAAAGAGTTAGGTATTACTAC
TTTATATGTTACTCATGATCAAGAGGAAGCCTTGACTTTATCGATAGAATTGCAGTCTTTAACAATGGATACATCGAAC
AGGTCGGTACACCAGTAGAGATTATCATAATTCTCAAACTGAATTTGTATGTGATTTTATTGGAGATATTAATGTTTTG
ACCGATGAAACAGTCCACGAAGTATTATTGAAAAATACAAGCGTTTTCTAGAGGATAAAAAAGGATACATTCGATTAGA
GAAAGTTCGATTCAATCGTGAAACTGAACAAGATTTTATTCTAAAAGGGACAATTATTGATGTGAGTTTTCTGGAGTTA
CAATTCACTATACAATAAAAGTTTCTGAAAGTCAGATTCTAATGTAACAAGTATTGATAGTCAGGCTGCTATTAGATCT
GTCGGAGAAAGTGTGGAATTATTTATCACACCATCAGACGTTCTGCAATTTTAA
4346.3
ATGCGTCATAAATTAAATTTAAAAGATTGGCTTATTCGTTTAGGGTTAATCTGGTTCTTAGTAACATTTATTATTTATC
CAAACTTTGATCTAGTAGTGAATGTATTTGTAAAAGGAGGAGAATTTTCCCTTGATGCTGTACATCGTGTTCTAAAATC
TCAGAGGGCACTTCAGAGTATTATGAACAGTTTTAAGTTAGCATTTTCACTCATTATTACAGTTAATGTCGTAGGTATT
CTTTTGTGTCTATTACAGAGTACTTTGATATTAAAGGTGCTAAAATTTTAAAATTAGGTTATATGACCTCTTTAATTTA
TGGAGGAGTGGTTTTAGCGACTGGATATAAATTTGTCTATGGTCCTTATGGATTGATTACAAAATTTTTACAAAATGTT
ATCCCTTCTTTAGACCCTAACTGGTTTATTGGGTATGGTGCAGTCTTATTCATTATGACATTTTCAGGAACTGCTAATC
ATACATTGTTTTTAACAAATACAATTCGAAGCGTTGACTATCACACTATTGAGGCTGCTCGAAATATGGGAGCAAAACC
ATTTACTGTTTTCCGAAAAGTAGTGTTACCAACCTTAATTCCAACTCTATTTGCACTTACTATTATGGTTTTTCTTAGT
GGTTTATCTGCAGTAGCAGCACCCATGATTGTTGGTGGTAAAGAATTTCAAACTATAAATCCAATGATTATTACATGCA
GGGATGGGGAATTCTCGTGATTTAGCTGCCCTACTTGCAATTATTTTAGGTATTGCAACTACAATTTTGCTTACTATCA
TGAATAAGATAGAAAAAGGTGGAAATTATATTTCTATCTCTAAGACTAAAGCGCCTCTTAAAAAACAAAAAATTGCGTC
TAAGCCTTGGAATATCATTGCTCACATTGTAGCATATGGATTGTTCACAGTTTTCATGCTTCCACTAATTTTTATAGTA
TTATACTCATTTACAGATCCAGTTGCAATTCAAACAGGTAACTTAACATTATCAAACTTTACTTTAGAAAATTATCGCT
TATTCTTTAGTAATAGTGCGGCATTCTCTCCATTCTTGGTCAGCATTTATTTATTCTATTATTGCTGCGACAACAGCAA
CAATTCTCGCAGTTGTATTTGCTCGTGTTGTCAGAAAACATAAATCTCGTTTTGATTCTTATTTTGAATATGGTGCTCT
ACTTTCCTTTGGTTACTACCAAGTACACTTTTAGCAGTAAGTTTATTATTACTTTTAATCAGCCACAATTTCTTGTCTT
GAATCAGATTTTGGTAGGTAGTTTGGTAATTCTACTTATTGCATATATAGTTGTAAAAATCCCATTTTCTTATAGAATG
GTACGTGCTATTTTATTTACTGTTGATGATGAGATGGAAGATGCAGCAAGAAGTATGGGTGCTTCACCTTTTTTATACT
ATGATGAAGGTTATCATTCCATTTATTTTACCGGTTGTTCTCTCTGTTATTGCTTTAAACTTTAACTCTTTATTAACTG
ACTTCGACTTATCTGTATTCCTTTACCATCCCCTAGCTCAACCATTAGGTATTACGATTCGATCTGCAGGTGATGAAAC
AGCAACATCTAATGCACAAGCTCTGGTATTTGTTTATACAATTGTTCTGATGATTATTTCTGGAACGGTATTATACTTC
ACACAAAGACCGGGGCGTAAAGTAAGGAAATAA

TABLE 2
MEELVTLDCLFIDRTKIEANANKYSFVWKKTTEKFSAKLQEQIQVYFQEEITPLLIKYAMFDKKQKRGYKESAKNLANW
HYNDKEDSYTHPDGWYYRFHHTKYQKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQ
RKIDVEPVFGQIKASLGYKRCNLRGKRQVRIDMGLVLMANNLLKYSKMKZ
MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVYADETLITHTAEKPKEEKMIVEEKADKALETKNIVE
RTEQSEPSSTEAIASEKKEDEAVTPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNW
YFKLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTFKLDEKLDEKDLKKNVRLTF
DGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLQKDGRENVIAVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKN
GTTILTPKLEEQQHGKVETHVTSKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKL
WTVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGPSLNGERIKFHGVSLHHDHGALGAEENYKAEYRRLK
QMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFDTWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVER
GKNNPAIFMWSIGNEIGEANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNYSEDN
YKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDRVGWGKTATASWTFDRDNAGYAGQFI
WTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAGIPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKI
PVRAYSNASSVELFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEIARDKITTAG
KPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVYPTANNLVRFQLHGQGQLVGVDNGEQASRERYKAQADGSWIRKA
FNGKGVAIVKSTEQAGKFTLTAHSDLLKSNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAE
RPVTWSSVDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLIDGSVEEYEVDKWEIA
EEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTVTVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAK
NAAVTVLQASAANGMRASIFIQPKDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLP
ADKVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKDQVELTIQANTEKKIAQSIRPVNVVTDLHQEPSLPATVTV
EYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDLEARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNG
HVSSAKVAWDAIRPEQYAKEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVSNVN
DKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVGVPKSYVIEYYVGKTVPTAPKNPSF
VGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHFSFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRI
QVDGKDLANFNPDLTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVLAKAENGDILGEYRLHFKDKSLLSHK
PVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAENLTKAGQFTVRGRVLGSNLVAEITVRVTDKL
GETLSDNPNYDENSNQAFASATNDIDKNSHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVTQ
GKQFFADSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAGDEINVTFKAIKAKAM
RWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELADFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSG
EDSFPVLVRLVSESGKQVKEYRIHLTICEKPVSEKTVAAVQEDLPKIEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKV
GKERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKCPQVSEKADTKPIDSSEASQTNKAQLPSTGSAASQ
AAVAAGLTLLGLSAGLVVTKGKKEDZ
MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSESFSESDEKQVDYSNKKNQEEVDQNKFRIQIDKTELF
VTTDKHLEKNCCKLELEPQINNDIVNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVT
GGGESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIISDIQDRLGHGTAVVAQIVG
DDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDGNDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYAN
QKGVIIVAALGNDSLNVSNQSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPAGS
TLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYKLKDQPYNYMFVKKFWKKHYQZ
MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFILDWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEE
SSSDLVINGKAPFAVYFQDYMAKKLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTL
VESQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYVKEFDYYSPVIIANNDYLKD
NKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKEKRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKE
NGILKEDLTDKGFTNEFVKZ
MKRTWRNSFVTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLVVMEMVSDKGIQYNNEKTLHMLHIDEG
ENPVSIQLFGSDEDSLARAAEFIQENTKTDIVDINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMR
TGWADPSLAVENALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAKQRIEEVGADA
VMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLINLKGENVAVREFRGLAPHYLRGTSGAAKLRGA
ISQASTLAEIETLLQLEKAZ
MIIKNPKLLTKSFLRSFAILGGVGLVIHIAYLTFPFYYIQLEGEKPNESARVFTEYLKTKTSDEIPSLLQSYSKSLTIS
AHLKRDIVDKRLPLVHDLDIKDGKLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFV
FSYFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYELESRNEQIVKLQNQKVSFV
RGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSINKIDQMSHLLEEVLESSKFQEWTECRETTVKPVLVDILSR
YQELAHSIGVTIENQLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEHLFDI
FYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISLZ
MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLTKYVTLLNDKALDSGLELAIHSEDENLRLSIGAATK
GRDIRSLFLESAVKYQILVYLLYHQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIHYFYFC
LFRKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQFQVTEEKMRGYFDNIFYLR
LLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLHTMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYE
LSQLCAQVYLYGYILQDRYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQIEYMAENGGQHMR
IGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKEQTPVYYLKNDLDMEDLVAIRQLLFTZ
MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLETGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEV
VSDTVSERAVVQQIAPHIPKSDPMLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPAANKVLSKDQVLERQPNLKKE
GLVGGGVYLDFRNNDARLVIENIKRANQDGALIANHKAEGFLFDESGKITGVVARDLLTDQVFEIKARLVINTTGPWSD
KVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYFDTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQED
VDYLLGIVNNRFPESNITIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVESAVS
KLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDILKAEFDRSFKLINSKTYPVSGGELN
PANVDSEIEAFAQLGVSRGLDSKEAHYLANLYGSNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRR
TNHMLFMRDSLDSIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKNZ
MMNELFGEFLGLILILLGNGVVAGVVLPKTKSNSSGWIVITMGWGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPW
ASVLPYILAQFAGAMLGQILVWLQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQA
GIGTFAVGTLIVGIGLSLGGTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVVGPVIGAALAVLVFSLFZ
MTKKKIERISVTHREKILWLKWYFMRDKEQPKYSVLERKMFDAAKNQDMLAYQKYATIKQITDIRVQTSEADILEAVKE
VYVYNHMNVIGACQRILFISQSPAYDKLNKWFNIYSDLYFSVVPLPKMGVYHEMVGIZ
MKNSNEAEMKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKERAVLEYLSQQASFSITVTRFAQMARYLV
LNDLPAKTTDDIGLGLAFYKCLAELDPKDLRVYGAIKQDPQLIQQLLELYHEMTKSQMSFLDLENLTDEDKRADLLLIF
EKVTAYLNQGQLAQESQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVIGAYASKKAYTSP
FSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLESSYDFSELALDVDEKDRENLQIWSCLTQKEELE
LVARSIRQKLHENSDLSYKHFRILLGDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDL
INLLRTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAPLETLFASRKQKAEKLLQ
KWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVLEQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVD
TVLVQSYDLIAPLTADFVYAIGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSAR
KQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSLVAYHQQGEMSDTEQDLTFVKVL
SRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALYPAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARS
HGNFLHRIFERALQLPNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIETTKEEA
NFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPHFFNGLNSQLPTYLAALKCREGEQNFFG
AMYLEMAEPVQSLMAVKSLAGAVVEASKSMKYQGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKI
LAGRFAINPYTENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREELNRZ
MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSAQNILVSASAGSGKTFVMAERILDQLARGVEISQLFISTF
TVKAATELKERLEKKISKKIQETDDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLI
LENEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWLSESFLKGFEKADFTSEKEK
LTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASR
KADLKPLADAYNEERKTQFAKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYT
IEILENFPQVRESYQEREHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQ
EGRLIILKENFRSSSEVLSATNDVFERLMDQEVGEINYDNIKQLVFANTKLTPNPDNKAAFLLYDKDDTGEEEESQTET
KLTGEMRLVIKEILKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNP
LQDYALVALMKSPMFGFDEDELARSLQKEDKVHENLYEKLVNAQKMASSQKGLIHTALAEKLKQFMDILASWRLYAKTH
SLYDLIWKIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAV
ELMTIHKSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEEL
QLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYR
FIGEDQLTREAIGELETKSPLQDSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEG
VEIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAF
FDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYE
EALSRAYSIENIEKYLILLGKDEVQVVKVZ
MELARHAESLGVDAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKNPRVIGVKNS
SMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPELFLKLNQLIADKDLETARELQYAINAIIGK
LTSAHGNMYGVIKEVLKINEGLNIGSVRSPLTPVTEEDRPVVEAAAALIRETKERFLZ
MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNTMDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHL
GRGKKEEVASDFYQFIYLALGLSVVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLG
LTKLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQEKLKALHLEKRIPLNMDKI
KEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSPLIIASHQSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTY
IGLGRWTALIFAAFTLTFLYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYLGLL
GYWGVAIPVYAIZ
MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQKYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYS
KAPINQSLSRAALETLSIIAYKQPITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGIN
HLEELPVIDELEIQAQESQLFGERIEEDENQZ
MDTMISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVIFNTAKLATDIENNVRVVVYIRKDVEDNSQTIE
KEGQTVTNNDYHKVYDSLKNMSTVKSVTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAK
KIEGVSEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMRLVGAKNSYIRGPFLLE
GAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPDLFSPLMIALLFVIGVFIGSLGSGISMRRFLKIZ
MKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLK
SGGYMAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKADGQHAEKEWLQIKGKDY
YFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKE
SWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMT
ANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKTTNENAAYYQVVPVT
ANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITTISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNAS
IPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHI
NALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNV
EYASDPYWGEKIASVMMKINEKLGGKDZ
MKKVLQKYWAWAFVVIPLLLQAIFPYVPMFQGAFYSFTNWTGLTYNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMV
VGEIALGIFIARVLNSKIKGQTFFRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAV
FVLLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILALKGGLTAFDQVFAMTGGGP
NNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVISIIQLRVSKKFEIZ
MMKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDNFFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVL
SLLAVMIFIPMAAYSIARNMSKRKAFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLY
VGYIKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVLNRDSKMWTLPLFQYNYAG
QYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAVKZ
MKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQSILSHKFFRLILQFVLFGSVLSAAFASL
EHFQIVKKFNYAFLSPNMQVWHQNRAEVTFFNPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQN
RTAFPAIIAGAIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMALFKQNPFWGEGP
LTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRLMMDMSQESGKRPIIGLYLSFLTVVAVHGIFDL
ALFWIQSGFIFLLVMCSIPLEHRMLVSDMTDZ
MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLIMGQLPFEGLNKSIASVFGANWTEPFMQVYSQTFAI
MGLISCFSIAYSYAKNSGVEALPAGVLSVSAFFILLRSSYIPKQGEAIGDAISKVVFGGQGIIGAIIIGLVVGSIYTFF
IKRKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQVPLQGLTGSLYGAIGIAFFI
SFLWWFGVHGQSVVNGVVTALLLDANKAMLASANLSLENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQA
LGKVAAFPAIFNVNEPVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFLVGGWQG
VITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQSZ
MKKDDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALDSTTVNLLETDPYITSGRHLVVPKDAPNQKVTASLP
VAHELESLQRDILACRRVWMSZ
MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVGSKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHY
PLSKDYNPGENPTAKAELVKLIKAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEIAASGLSLEEYYGFEGGDYVDZ
MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKCLAAEAE
LPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIR
PFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPFPRDAILGIGNEILDYDLAIAELSNNINVEDLQQL
FSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHY
QNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEI
VSILGIATNNLSKKTKNDIMNTVLYIEKIDRZ
MRKFLILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIYFREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQ
ITEWRLNKQGIPVFKLSNHQFIAADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVE
GREFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQDEKMYAASVLKLSYLYYTQEK
INEGLYQLDTTWKYVSAVNDFPGSYKPEGSGSLPKKEDNKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKM
SAIMGDDWDPKEKLISSKMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYADSPF
ILSIFTKNSDYDTISKIAKDVYEVLKZ
MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYTELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTS
KEETGIQFTPSVTKVEKFTSTILPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMG
GGNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGARIPAGVLLEGPPGTGKTLLAK
AVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKKAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEM
DGFEGNEGIIVIAATNRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFVGADL
ENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHEAGHTIVGLVLSNARVVHKVTIVPRG
RAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGRVAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGN
HAMLGAQSPQKSISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYETGKMPEAVE
EESHALSYDEVKSKMNDEKZ
MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGNSQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAY
AENPSQDKVEGIRDLFLTILKSDKDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDS
QWVISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQHTVYSSSSKMEAMKPYIDTG
QGYTPGHKSYVSQEIAGTDWTVLGVSSLEKLDQVRSQLLWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIA
SGAQNLRAKEVGAYELREVTRQFNAMLDQIDQLMVAIRSQEETIRQYQLQALSSQINPHFLYNTLDTHWMAEFHDSQRV
VQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINENVAFDNLVLPKLVLQPLVENALYHGIK
EKEGQGHIKLSVQKQDSGLVIRIEDDGVGQDAGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIY
INRIETSZ
MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGNSQTTISQTSHFIQSYIKKLETSTGLTQQTDVLAYA
ENPSQDKVEGIRDLFLTILKSDKDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQ
WVISVTQELVDAKGANLGVLRLDISYSTLEAYLNQLQLGQQGFAFIINENHEFVYHPQHTVYSSSSKMEAMKPYIDTGQ
GYTPGHKYVSQEKIAGTDWTVLGVSSLEKLDQVRSQLLWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIAS
GAQNLRKEVGAYELREVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFHDSQRVV
QVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINENVAFDNLVLPKLVLQPLVENALYHGIKE
KEGQGHIKLSVQKQDSGLVIRIEDDGVGFQDAGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIY
INRIETSZ
MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANSLNALGLSFLNMLSLVSGNALKNFSIFALGVSPYIT
ASIVVQLLQMDILPKFVEWGKQGEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILT
AGSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSIIFVIILIITVLLIIYFTTTYV
QQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFASSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIA
MYALLIILFTFFYTFVQINPEKAAETYKRVVPISMEFVLVKVQKNICLNFFVVLQLLVPSSLVZ
MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKIYQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTP
ISLIGAATDATDYVVLAKALDKAAKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINM
TAVADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGVVKRALEKVRGQSFDVVAET
VKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPAVGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMA
CNQVGGLSGAFIPVSEDEGMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKTTAV
RIIPKGKEGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKNZ
MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNPASQVYVRNKERSALAAGFRSEVVRVPETITQEELL
DLIAKYNQDPAWHGILVQLPLPKHIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEG
KNAVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLSKVAAKADILVVAIGRAKFVTADFVKPGAVVIDVGMNRDENG
KLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQAALRTLDRKZ
MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGY
ATKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNQFPEEILTKIEEFSGRKVIREANKPYSGTAVIYDFGPRQMETGEL
IIYTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRRDLAVSPFFPTVLDKL
NEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTLLKTMGLAEPEKGFSFTNLVDFDALYGHRRNAHGYRDCLHE
FDERLPEIIAAMRENDLLLITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETAMIG
ESFLDKLVZ
MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNV
GMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLV
GFSNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAA
ISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLAS
LLTLAILYLMZ
LFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGVSVAGNIITIYQAIFIALGAAISSVISKSIGQKDQS
KLAYHVTEALKITLLLSFLLGFLSIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPL
YVSFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDKELLTLALPAAGERLMMRAG
DVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATATVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIY
VLGVPLTHLYTTDSLAVEASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVLGWG
LPGIWAGSLLDNGFRWLFLRYRYQRYMSLKGZ
MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLTYLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVA
FQSVAPLIMIGQSHGSGAMFGALIASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQS
LLLAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTPLYFGMPTFEISSIVMMCII
ATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAVLLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLV
LLGLLPKFGALAQIIPSSVLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTAFQM
FFSNGIVVASLLAIVLNAVLNHKKKZ
MKDRIKEYLQDIGKVTVNDLAQALGKDSSKDFELIKTLSLMERKHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFG
FVSLEGEEDDLFVGKNDVNYAIDGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKN
QKISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVLESMDIVSEFPEAVVKEAESV
PDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIKALKNGNLEFGVHIADVSYYVTEGSALDKEALNRATSVYVTD
RVVPMLPERLSNGICSLNPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHKIVSS
IELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIESFMLMANETVAEHPSKLDLPFIYRI
HEEPKAEKVQKFIDYASSFGLRIYGTASEISQEALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYY
THFTSPIRRYPDLLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYVGEEYDAVVS
SIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVGQQIRIRVERADKMTGEIDFSFVPSEFDVIE
KGLKQSSRSGRGRDSNRRSDKKEDKRKSGRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTKZ
MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGSVPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILW
FAQLGMVVAIPLTIRFILPIFARIDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINI
LIILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLANGKFLAANEKLFDPNLLSNS
IFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKMLFTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQD
QIFMYFIAYQLPVGITGLILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIGVSI
VMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMVFIKYFLPPTAVSYWAYSLISISVS
VVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSSWEVRHZ
MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDGSQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGY
VTSHGDHYHYYNGKVPYDALFSEELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQ
EHVKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLSASELAAAKAHLAGKNMQPS
QLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELYDSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFI
PYSKLSALEEKIARMVPISGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAYIVR
HGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRIIAEDESGFVMSHGDHNHYFFKKDLT
EEQIKVRKCNIZ
MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSLTYLQNRGAAFSILQDQQLLFAVTTLVVVIGAIWYL
HKHMEDSFWMVLGLTLIIAGGLGNFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGNZ
MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDTVKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEV
RKDLGVFVDTGLPDKEIVVSLDILPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAI
VYRLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSFEMLENDAQMILTYLESNGG
FMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQDQFGTELIZ
MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHSLESRLESRIAANERAINENEEKLSQMSDTSSEEYQ
FAKNNLDVQKNLLTRKTEILTLLKEGRWKEAYYLQWQDEEKNYEFVSNDPTASPGLKMGVDRERKIYQALYPLNIKAHT
LEFPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISSLGVGVGYVTVLFIGICGFS
FLVGSLISGGGQLDYPYPIYSLVNQEVTIGKIQDVLFPGLLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLL
FGIQTIQPLQRIAHLIPFTYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKEFFNRFZ
MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVGFLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNN
EAIVAVALTTYGSATAMIMFAGMVFNILLIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIM
SISPAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRDSTVSITLSMAVIYIIVAI
FAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVRLILGEIVPAFKGISERLVPNSKPALDCPIVYTTYAPNAV
LIGFISSFVGGLVSMVIMIASGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGLG
FQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSKIKKPSATEEZ
MIKTFLSALSVILFSIFPPTYSFFPSSNLNIWLSTQPILAQIYAFPLATATMAAILSFLFFFLSFYKKNKQIRFYSGIL
LLLSLILLLFGTDKTLSSASNKTKTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQV
GLSMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDIIALHTAPPLPGLMEIWKQDL
NIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDALNALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDI
VSFQNSDHRCIFTEITFZ
MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKTVESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKI
KGLENVSPELETVAKLKDKEAVTGEQSVERDDLSAADNNLVSLTALEDSSKDVTFTTSSAFNLKEGRHLQKGDSKKILI
HEELAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFTDYESSQTLLGNSEAQVSA
ARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQIKDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVY
EVGILLALGKGKSSIFLQFCLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAESY
VFLVLLSCLSVALCFLFLFRKSPKEILSSISZ
MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKASQETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDI
KKITENKAIESYVKRINAIGDLTGYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTND
DKDKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTYSQELYENTAITDIHTAAKL
YGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWKSYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLL
ALLLSLWINARRKEVGILLSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASKAAQ
ASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQPKELLLDGEZ
MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQSKETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGA
LTSVAGVFIYGHIIGTIYNYIGIVIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIDWLDKGNRFDRFFIFMMIWPISPA
DFLCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQMLZ
MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGSSMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEA
SAKEAIKEEKLKGYLTIDQEDSVLKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTATLSQEQEKRLAQTIQFTEKID
EAKENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYARMMALFLVILTHIGIYVVG
GLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISLFMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTA
LGAAGDNLLLKIGSYIPFISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRA
LSYKZ
MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQSYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFV
GDLNRAEKGARLHTDTFQPQGVEGLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGM
ALGVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQFGQAEPSSTRKNLEQKKLL
ZMLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPVFNKPADKQVPAEILEIAAKIEEADGVIIGTPEYD
HSIPAVLMSALAWLSYGIYPLLNKPIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLV
DLDVIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDPDWENLZ
MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHIDTAAIYQNEESVGQAIKDSGVPREEMFVTFKLWNSQ
QTYEQTRQALEKSIEKLGLDYLDLYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLE
TATIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKSVAQIALAWSLAEGFLPLPK
SVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVDDVDFZ
MRCKMLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPDDILDFILVAFPLAILGARLYYVIFRFDYYSQ
NLGEIFAIWNGGLAIYGGLITGALVLYIFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGF
IRDQMYIEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMRTDSLMFFGFRVSQWL
SVVLIGLGIMIVIYQNRKKAPYYITEEENZ
MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDPEYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEIT
VDSILAQTKSYAFQATEASKNQLNNLKEQWQEKAEALDDSEEIVIDITEEZ
MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVYLKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAA
GLHHFAVVKNLFHLVQLVALVTLPSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVG
DDTWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRKZ
MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEMLAFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKT
YIQMKMLNTGKGPAVRALRAQADKELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTG
TALRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTEIQPGDEVPNHFSYTSRDED
YVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLS
TSLPEDVQRDLVHSIKGLENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGINAA
LKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMRLTEMGREIGLVDDERWARFEIKKN
QFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTDAVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEG
YISKAMDQVAKMKRMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEGKNRSISKT
LQKSKZ
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMM
VSAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKL
LSLTPKEFESDKNPFFEVFKVSKVTAQZ
MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVAREITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEM
GFKCFRTSIAWTRIFPKGDELEPNEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAE
VVFKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVASARAVKIGHEINPDFQIGCM
IAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYPEHIFKYWERKGISVDFTAQDKEDLLGGTVDYIGFSYYMSF
AIDSHRENNPYFDYLETEDLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFTVENGFGAIDQVAADGMVHDDYR
IEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDNGKGSYNRSPKKSFGWYKEVISSNG
ESVEZ
MDQQNGLFGFLENHVMGPMGKLAQFVVRAITAAGMAAVPFTIVGSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYM
VANYATMGSLSLYFVLSLAYELTKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAM
GNVVARFGTGIFTAHMAIVVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVVAFVVIFINGLLVAMGTDIKVIAI
PFGFVSNLTNSWIGLMIIYLLTQLLWWGIHGANIVFAFVSPIALANMAENAAGGHFAVAGEPSNMFVIAGGSGATLGLC
LYAFASKSEQLKAIGRASVVPALFNINEPLJFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPIIAQVPWPTPV
GIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYGQKLVKEEQGIZ
MKKFYVSPIFPILVGLLALFGVLSTFUPVNNNLLTVLILFLFVGGYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTAL
LEQMPVGVMKLNLSSGEVEWFNPYAELLLTKEDGDIDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDV
SREQAITDELVTSRPVIGIVSVDNYDDLEDETSESDISQINSPVANFISEFSEKHMMFSRRVSMDRFYLFTDYTVLEGL
MNDKFSVIDAFEESKQRQLPLTLSMGFSYGDGNHDEIGICVALLNLHLAEVRGGDQVVVKENDETKNPVYFGGGSAASI
KRTRTRTRAMMTAISDKIRSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEKEGV
TKLLSVKDAMGMVTNRSLLILVDHTALTLSICEFYDLFTQTIVIDHHRRDQDPPDNAVFITYIESGASSASELVTELIQ
FQNSKKNRLSRMQASVLMAGMMLDTICNVFSRVTSRTFDVASYLRTRGSDSAIQEIAATDFEEYREVNELILQGRKLGS
DVLIAEAKDMKCYDTVVISKAADAMLAMSGIEASFVLAKNTQGFISLSARSRSKLNVQRIMEELGGGGHFNLAAAQIKD
VTLSEAGEKLTEIVLNEMKEKEKEEZ
MKEKNMWKELLNRAGWILVILLAVLLYQVPLVVTSILTLKEVALLQSGLIVAGLSIVVLALPIMGARKTTKLASFNFSF
FRAKDLARLGLSYLVIVGSNILGSILLQLSNETTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRG
KENLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAFCLLALVVIMSRTLGISVZ
MKEKNMWICELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVALLQSGLIVAGLSIVVLALFIMGARTKLASFNFSFF
RAKDLARLGLSYLVIVGSNILGSILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRG
KENLGFVVGTTVFALLHQPSNLPSLLIYGGMSTVLSWFAYKTQRLEMSILLHMIVNGIAFCLLALVVIMSRTLGISVZ
MDTQKIEAAVKMHEAVGEDANREGLQETPARVARMYQEIFSGLGQTAEEHLSKSEIIDDNMVVEKDIFFHTMCEHHFLP
FYGRAHIAYIPDGRVAGLSKLARTVEVYSKKPQIQERINIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
TTVARGLFETDKDLRDQAYRLMGLZMKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYSQLLQHFPENH
WPILLFVGITSVLLLLWGGTATYMEAPDKLFLLVGEEEIKLHLKRQTGISLVFWLFVQTLFLLLPAPLFLAMGYGLPVF
LLYVLLLGVGKYFHFCQKASKFFTETGLDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPK
IWQNLYLRYLRNGDLFALSLRLLLLSLLAQVREQAWIATAVVVLFNYLLLFQLLALYHAFDYQYLTQLFPLDKGQKEKG
LQEVVRGLTSPVLLVELVVGLFTFQEKLALLALLGAGLVLLVLYLPYQVKRQMQDZ
MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEWFKLLGRKMEVVNSTIRSVHIDKELFESYKGPHINYA
SYFRFFATEVVESDRVLYLDSDIIVTGELATLFETDLKGYSIGAVDDVYAYEGRKSGFNTGMLLMDVAKWKEHSIVNSLL
ELAAEQNQVVHLGDQSILNIYIFEDNWLALDKTYNYMVGIDIYHLAQECERLDDNPPTWHYASHDKPWNTYSISRLRELW
WVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVTWSADIKHLEYLVQRLPDWHFLAAPCDCSEELTSLSQYTNVTVYQN
VLHSRIDWLLDDSIVYLDINTGGEVFNVVTRAQESGKCIFAFDITRKSMDDGLYDGIFSVERPDDLVDRMKNIEIEZ
MTKIYSSIAVKKGLFTSFLLFIYVLGSRIILPPVDLNTKDFLGGSTAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMIL
WQMFSFSKRLGLTSTSIEIQDRKMYLTLLAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
GGSIVILLSSMVLNIPQDVLETFQTVHIVTGIIVLLALLTLVPSYLLALMYRARYLVPVNIKIGLHNRPKRYSYLEIML
NPAGGMPYMYVMSFLSVPAYLFILLGPIFPNHSGLAALSCEFMVGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMK
KSGEYIYGIYPGADTSRFINRLVLRFSVIGGLFNVIMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEVKALR
LNETYRPLIZ
MSSLSDQELVATVEIRQRLSEGESLDDILVEAIAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKTLTATM
PVYLNAFSGEVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMKAEEKKLIYASDIIYTTNSNLGFDYLND
NLSNEEGKFLRPFNYIIDEIDDILLDSAQTPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKS
AENFLGIDNLYKEEHASFARHLVYAIRAHKLFKDKDYIIRGNEMVLVDKGTGRIMEMTKLQGGLHQAIEAKEHVKLSPE
TRAMASITYQSLFKMPNKISGMGTGKVAEKEFIETYNMSVVRIPTNRPRQRIDYPDNLYPEKVYASLEYIKQYHAKGNP
LLVFGSVEMSQLYSSLLFREGIAHNVLNANNAAREAQILSESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVIGTE
RMESQRIDLQIRGRSGRQGDPGMSKFPVSLEDDVIKKFGPSWVHKKYKDYQVQDMTQPEVLKGRKYRKLVEKAQHASDS
AGRSARRQTLEYAESMNIQRDIVYKERNRLIDGSRDLEDVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPD
YIDVDKTAVRSFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLLAIDDNWVEQVDYLQQLSMAIGGQSASQKNPIVEYY
QEAYAGFEAMKEQIHADMVRNLLMGLVEVTPKGEIVTHFPZ
MIGTFAALVAVLANFIVPIEITPNSANTEIAPPDGIGQVLSNLLLKLVDNPVNALLTANYIRILSWAVIFGIAMREASKN
SQELLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGVGSLANYGILLVLLVTTMLFVAPVVNPLIAFFFMRRNPYPL
VWNCLRVSGVTAFFTRSSATNIPVNMKLCHDLGLNPDTYSVSIPLGSTINMAGVAITINLLTLAAVNTLGIPVDFATAFV
LSVVAAISSCDASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIGVIQDSCETALNSSTDVLFTAVAEYAATRKKZ
MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTRRSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLG
LYLAFYVPLAYKMGWEIGITPSTVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMRQRQSRILRNMAQQINTCHLAAS
ESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVFRNRSLPKTREEFETRATLLQLLREAICTFIQVKVDFYQKYRQZ
MEIMSLAIAVFAVIIGLVIGYVSTSAKMKSSQEAAELMLLNAEQEATNLRGQAEREADLLVNEAKRSKSLKKEALLEAK
EERKYREEVDAEFKSERQELKQIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRIAGEYVAESTNSTVHLPDDTMK
GRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFDPIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIRE
YGEAAAYEIGAPNLHPDLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAIDHEVEG
SHVEIGMELARKYKEPPVVVNTASHHGDVEAESVIAVIVAADALSAARPGARSESLESYDCRLMDLEEIANGFEGVQTS
FALQAGREIRIMVNPGKIKDDKVTILAHKVRKKIENNLDYPGNIKVTVIRELRAVDYAKZ
MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSEKSTLRALEEIESGNVTIHPDPEGKREAVRRIEEEK
RRKEEEEKKIKEQIAKEKEDGEKIZ
MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQLYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIA
IMDGDQFGSDFVKLNPNSKIPALLDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGG
FGHFFNYAPEKLEPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLVQGNLYQGSAKFLDASSYQNL
VKWAEKIANRPAVKRGLEVTYTEIKZ
LASLITSIIMEYVGFDVLRDTIQKILSREETVIDPLGATLGHSAAIMFVVYLYNTRLSKKSNSNALKAAAKDNLSDAVT
SLGTAIAILASSFNYPIVDKLVAIIIFFILKTAYDIFIESSFSLSDGFDDRLLEDYQKAIMEIPKISKVKSQRGRTYGS
NIYLDITLEMNPDLSVFESHEIADQVESMLEERFGVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLT
DDFVYIRQDGEQMDKEAYKTKKELNSAIKDIQITSISQKTKLKYELDGIIHTSIWRRHETWQNIFHQETKKEZ
MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVASGRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDL
YEATMSRDFYLATFEKLKTSPYVDINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTE
ETLEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDNLNDLHMMQVVGHPVAPENA
RPEILELAKTVIGHHKERSVIAYMEGLZ
MADIKLIALDLDGTLLTTDKRLTDRTTLQAARDRGIKVVLTTGRPLKAMDPFLHELGTDGQEDEYTITFNGGLVQKNTG
EILDKTVFSYDDVARLYEETEKLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACGDEANDLSMIEWAGLGVAMQNA
VPEVKAAANVVTPMTNDEEAVAWAZEEYVLKENZ
MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQLDYRPDQARQASQLDQKDLEVVVSDRLQEVRIELH
QGLTQVRQEMTDNLLQTRDKTDQRLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTV
ARDVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPGQGDQEYVYLPIDSKFPLAD
YYRLEEAYETGDKDEIERCRSLLASVKRFARDIRNKYIAPPRITNFGVLFVFTEGLYSEIVRHPVFFDDLRREEQIIVA
GPSTLSALLNSLSVGFKTLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTLRHIE
LSEGEPALDLLHFQENEEEYEDZ
MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEIGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQV
NQITLRLPQAGEPNDPADPKVKSPVDVKEIRDYMSQMWKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
HTATMVRAGASEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIALIDSEITKTVMELGIDDTKEEVV
LLRMVILSHHGLLEYGSPVRPRIMEAEIIHMIDNLDASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLDZ
MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAPIEGIYETQPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSA
AIDVAFFILMVGGFLGIVNKTGALDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGF
DSLTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFVYRYADKIQKDPTKSLVYST
RKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMVLSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGT
WYFPEGAMLFAFMGILIGVIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGLSSQ
VFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGVLNLIAPTSGIVMGALALGRINIGT
WWKFMGKLVVAIIVVTIALLLLGTFLPFLZ
MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVPILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKT
ILLAILVGMFTVMQSVAPLVTYLFVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATI
GLLPTTCINLVLYIISSPLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLPVSANLLEIFSNTIWVSSIILVFV
TELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAAKWEPQLFTPNLKTIQNPCLSLDPGWFLFSPNGCFLLDKKE
FPLYGISVEKNTKRKETHMNSLPNHHFQNKSPYQLSFDGGHLTQYGGLIFFQELPSQLKLKERISKYLVTNDQRRYCRY
SDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQLASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQL
NQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRM
DSGFATPKLYDLIEKTGQYYLEKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETLYQAGSWSHKRRVCQFSERKEG
NLFYDVISLVTINMTSGTSQDQFQLYRGRGQAENRKEMKEGFIGDKTDSSTLIKNEVRMMMSCIAYNLYLPLKHLAGGD
FQTLTIKRFRHLFLHVVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMHZ
MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYEVLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLL
FYKHYRKSKDGKWVFYLVSFLSLLPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLL
FMPTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLPPLKNLALQSGGFFNLYALA
VMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPFLSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKN
RNVTSSMAYIVNMLIMGFWHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVTFHV
VMLSFLIFSGFLNNLWFKKZ
MLKRLWMIFGPVLIAGLLVPLLIIFYPTEMHHNLGAEKRSAVATTIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFD
GAHPAVLAEKYNRSYRPYLLGQGGAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLK
HQSGDQASQYAATRLLQQFPNVAMKDLVQKLASKEESTADNEMIELLARFNERQASFFGQFSVRGYVNYDKHVAKYLKI
LPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQIKKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIF
IIPPVNKKWMNYAGLREDMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLSNPTP
APTYHLNERFFSKDWATYDGDVKEFQZ
MEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAAVKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMT
QAEYKAYYTKGYHTDVTKINITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFSDHN
VAPVKEHPHIFIGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAHZ
MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWNSETGCATATDIALATGLANNTLTTMIKKLEEQKLV
IVSPCGKDKRKYLVLTELGKSQKEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEVZ
MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFLRYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGI
GTLPALTALVIYAIFPILQNTITGLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAAL
IGAGGLGSFILLGIDRNNASLILIGALSSAVLAIAPNFLLKVMEKKLRTIFSGFALVALLLGLSYSPALLVQKEKENLV
IAGKIGPEPEILANMYKLLIEENTSMTATKPNFGKTSFLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQV
ARDGIAKQDHLAYLKPMSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGLNLNVA
TIEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMKEALLKIIIAPELERVLNTLAGKITES
QMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKKZ
MMHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWDDLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVD
WIGMKSLTGIIVIFVSEGRASNYLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVAR
KLDGKGWTKYLVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWIFWAWTNVFSIYLWWGESLQIQGK
YLIYLINSLVGWYQWSKAAKQNTDLLNZ
MRNMKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDAIAIGISAFLETISNREEDNQYTLGYKRFSLLG
ALVTAVILVTGSVLVILENVTKILHPQPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVIL
MAIVLRFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNVASLNQLNLWTMDALEK
NAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLETHQTHKRKVCDLERSYEHQHZ
MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTMLKMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGY
VLQAIALFPNLTVAENIALIPEMKGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFL
MDEPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVANPETILKAPATDFVADLFG
GSVHDZ
MSAVAISAMTKVMQETHGNPSSIHGHGRQAGKLLREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKH
IITTAIEHHAVLETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFVNNETGNLLPIAEIGQILKQHPA
AYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFDSYLHGGDQEQKKRAGTENLPAIVGMVAALK
EDLEKQEEHFQHVQNLEAFLAELEGIQYYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSH
VLEAMYGANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGGZ
MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQVESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNI
WGQIICLLLIQIGGLGLMTFIGVFYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLI
PQLGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVWFDLAGHVGRKKKGRLHFHT
KLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVLVSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAP
GGTAGGLKITTFFVLLVFARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLVFET
ISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIHYMKADISIGZ
MSDRTIGLGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEPVLARGVIGDITDEELLRSAGIDTCDTVVVATGENLE
SSVLAVMHCKSLGVPTVIAKVKSQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSW
AGQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVALNSZ
MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQTQEIAECLASKYPNIVRAIYQENKCHGGAVNRGLVE
ASGRYFKVVDSDDWVDPRAYLKILETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSK
GQYTMMHSLIYRTDLLRASQFZ
MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADGLNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKP
EGVTGNTNSLPTPTERTEVSEEISPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKEN
TKDSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLLKASDNAPWSDNGTAICNPALPPLEGLTKGKYFY
EVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGKADLTNLVATKNVDININGLVAKETVQKAVADNVKDSID
VPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVALDG
NVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLISKETVQKAVADNVKDSIDVPAAYL
EKAKGEGPFTAGVNHVIPYELIAGDGMLTRLLLKASDKAPWSDNGDAKHPALSPLGENVKTKGQYFYQLALDGNVAGKE
KQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLISKETVQKAVADNVKTVSMFQQPTZ
MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTIVASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKD
FPSNLEVQGPVEFQQLGQTFNEMSHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHY
LATIGRQTERLNKLVEELNPLTLNTARNQVETTSKDSIPLDKLLIECMSEFQFLIEQERRDVHLQVIPESARIEGDYAK
LSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSVTDEGQGIAPEDLENIFKRLYRVETSRNMKITGGHGLGLAIAREL
AHQLGGEITVSSQYGLGSTFTLVLNLSGSENKAZ
MFGQTAQHGLTNSLKDFWFLLNIGPQLAFFCQMLRCSRSVEQGTGNHRREFNMIQQIFSHFGMTHLGQIKLVYQESIDL
ELLVNALNHHLLIDRLVLTPNQITIEIDRQIVHGLDLLKGRKDKEIIDIKSMFRQLELASTQQICPINQRVHHGILAFG
EISDLVPAKNLPNRQDZ
MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAAALLKEQPEKFASALILQLLPGTQGLYGFVIGILIW
LQLTPELPLEKGVAYFFVALPIAIVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRVZ
MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPNVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCG
EAAHFQETVIVGDVTTYLNYISCDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFT
MFEEKSZ
MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKSTLSAAIMGNPNYEVTKGEVLFDGVNILELEVDERAR
MGLFLAMQYPSEIPGITNAEFLRAAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQ
LLMLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHVMMEGRVVLSGGPELAARLE
REGYAKLAEELGYDYKEELZ
MPYKRQRSFSMALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVINLSVKFDAEDRLEDIAFLNSGCTIS
TASASMMTDAVLGKTKQEILELATIFSEMVQGQKDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQZ
MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETFKEGILAREALTSTGLGDGIAMPHSKNAAVKEATVL
FAKSNKGVDYESLDGQATDLFFMIAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQ
APANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDIRKAKAIIIAADKAVEMDRF
DGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAKAATASNEKQSLGGALKHLMSGVSQMLPFVIGGGIMIALAF
LIDGALGVPNENLGNLGSYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIPYAAG
GEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLGTILTGFVMLAVNIPMAAINTAMNDF
LGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAYVFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTK
EERNSGLTNIIMGLSFITEFAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNALLYLVSVLV
GAIVSGVVYGYLRKPQAZ
MANKNTSTTTRRRPSKAELERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGLLIYLFFFK
WIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIG
TYFIGSILILVGSLLVSPWSVYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPV
DMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPSLQLFAPDKPKDQS
KEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLI
GIEVPNSDIATVSFRELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARP
DQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNIAGFNAKVEEFNSQSEYKQ
IPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTI
LDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGDPL
FEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQQZ
MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQIGALTAVFSLRESFDESVHFGTSRILGNSIGGLYAL
VFFLLNTFFHEAFWVTLVVVPICTMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAII
VNYDIDRIRLFLEKKEKZ
MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSRDIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELY
MEDALVWMRPVQHQVLLKTLPGLAQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEEZ
MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYPNSVDTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNR
TFSSLFYLCIACTILTTAVYILAYPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVS
IFLFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVFANANMLFTFLDRLFLVKTG
IDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGKGDKEAYVSLVNRGSRIFHFFIIPLSFGLMVLGPNAILLYG
SEKYIGGGILTSLFAFRTIILALDTILGSQILPTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTMLSET
SLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLPFLINTGLIVLLSAISYISLLVTKD
SIFYEFLNHVLALKNKFKKSZ
MELFMKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVIMERYFQIDDAHLSKEIQKFPSFS
ILDDCYPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAICGIDTAAHMA
ALQNGGKTIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLI
TCERAMEEGRDVFAIPGSILDCLSDGCHHLIQEGAKLVTSGQDVLAEFEFZ
MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRHEGFIPWDDDIDLSMPREDYQRINIFQKEKSKYKLL
SLETDKNYFNNFIKITDSIKIIDTRNTCTYESGIRDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKDW
IRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKTIDLPFENLSLPAPEKFDTILTQ
FYGDYMTLPPEEKRFYSHEFHAYKLEDZ
MTKINHLTTQNKDLRDLVSDLTMTIQDGEKVAIIGEEGNGZSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKVPED
LKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLET
VDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYDSYSEQRKANFAKQSQQAANNQRAYD
KTMEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQL
EKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHKKLQLDLSPIAYLSKT
GEKEELQKIQSHLSLNFSYPEMQHQIRSLGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKFATYPGCLITV
SHDRRFLKEVCSIIYRMTEHGLKLVNLEDLZ
MKPKTFYNLLAEQNLPQQKEQFERYFELLVEWNEKINLTAITDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAG
FPSLPMKILYPELDVTIIDSLNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELTI
PYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKKKETPNKYPRKAGMPNKRPLZ
MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATGRPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETAT
GHEIISEESLTYEDYLDMEFLSRKLGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFID
EPEILDAAIEKIPAEFERYSINKSAPFYLELLKKNVDKCSAITHLAEKLGLTKDETMAIGDEENDRAMLEVVGNPVVME
NGNPEIKKIAKYITKTNDESGVAHAIRTWVLZ
MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRRNDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAA
TSPAEAMKSDALTRQVSCIFAVAESYPDLKSANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
FKAADFLQTPEEEKSVPKVDFSGLGDZ
MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLVIALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTA
PDLYHVVEDMALVAQIPMPRVFIIDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTI
AVALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLVQLAISRQREFLADASSVEL
TRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKGGGFQKLFYTHPPISERIERLKQMZ
MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAvGKVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVES
YPVTEVFMEGATNQLDQEVLDDDLVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGRSGNDWQIMTEEEYQAQK
AVKKEENSPFAGLQGLFDGDEZ
MKRQLALVVPSGGQDSTTCLFWVMQHYEVEAVTFAYGQRHHLEIQITREIAKEQGIRHHILDMSLLGQITAQPDFATIH
ISYIPDKLCVESKLKLYLFSYRNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
EQRLFQHDLYPEKIDNRZ
MTETVEDKVSHSITGLDILKGIVAAGAVISGTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSL
SASESASTSASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKPASDYVASVTNVN
LQSYAKRRKRSVDSIEQLLASIKNAAVFSGNTIVNGAPAINASLNIAKSETKVYTGEGVDSVYRVPIYYKLKVTNDGSK
LTFTYTVTYVNPKTNDLGNISSMRPGYSIYNSGTSTQTMLTLGSDLGKPSGVKNYITDKNGRQVLSYNTSTMTTQGSGY
TWGNGAQMNGFFAKKGYGLTSSWTVPITGTDTSFTFTPYAARTDRIGINYFNGGGKVVESSTTSQSLSQSKSLSVSASQ
SASASASTSASASASTSASASASTSASASASTSASVSASTSASASASTSASASASTSASESASTSASASASTSASASAS
TSASASASTSASESASTSASASASTSASESASTSASASTSASASASTSASGSASTSTSASASTSASASASTSASASISA
SESASTSASESASTSTSASASTSASESASTSASASASTSASASASTSASASASTSASASTSASESASTSASASASTSAS
ASASTSASASASTSASASASTSASVSASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSA
SESASTSASASASTSASESASTSASASASTSASASASTSASGSASTSTSASASTSASASASTSASASASISASESASTS
ASESASTSTSASASTSASESASTSASASASTSASASASTSASASARQVRRPQPVHLNRHQPVRQPQQVLVHQLQHQRVH
RLQHQPVPRLQRQPVRQLQQVPVLQSQHQQVLQPQHRQVPRLQQAHQHLNQRRQAPQLQQVPVRQPQRRQVRQPQQVLV
HQLQHQRVHRLRRQPVHQSQQVPVRQLPHQQVPRLQQAPVRRLQQVLAPQPQPQPVRQPQQVSQRLNRHQRVRPLQQVL
APQPQRQQVHLQRQRVRLNRHQRVRPLQQVLAPQPQRQQVHRLQHQRVRPLQQVLAPQPQRQQVHRLQRQRVRLSQHQR
VRQPQQAHQLLNLHQPVRQPQHRQAPQLQQVPVRQPQRRQVRRLQQVPVRQPQQVPVRQPQRRQVRRPQPVHLNRHQPV
RQPQQVLVHQLQHQRVHRLQHQPVHQSQQVPVRQFRINKCLGFSKYZ
MGVETWFYSSICWLAIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAEFALGRSAGVSAIKTFGKLGKNNKY
NFIGWIGAFALFILLSFYSVIGGWILVYLGIEFGKLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQ
KGIERASKVMMPLLFIVFVFIIGRSLSLPNAMEGVLYFLKPDFSKLTSTGLLYALGQSFFALSLGVVMLTYASYWLDKK
TNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQLFDKMPFGTIFYVLFLLLFLFATVTFSVVM
LEINVDNITNQDNSKRAKWSVILGILTFVFGIPSALYGVMADVHIFGKFFGAMDFLVSNLLMPFGALYLSLFTGYIFKK
ALAMEELHLDERAWKQGLFQVWLFLLRFFVSSFQSSSLWSSLPNLCNQKGLEZ
MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNISLLLTPLGLQAFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAA
LAEVLYGSQFGLGALLSGFVQGLGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRF
ISVYFFCTILVRAIVKLYHQFATGGKAZ
MVKVATQTPIISLFLLYLSLETSFIPSIALTLSVVAFCILFMLYYRRFKMLAWMIILAILPSFANYWAVQLHGDASQAV
MLGTRAFVTVCIGLVFVSSVSLKELLLYLAQKGSRSWSYALIVVFNSPPLIQQEIKSLKEACLLRGQELHFWSPLIYSK
VLMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFLZ
MRKHQLQVHKLTILSMMIALDVVLTPIIRIEGMAPMSSVVNILAGIMMGPVYALAMATVTAFIRMTTQGIPPLALTGAT
FGALLAGLKYGRKFHYSALGEILGTGIIGSIVSYPVMVLFGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEFF
KKVQGYFFSERIDZ
MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADDSREVLDFTKQSQALFINLGHLSAEKEKAIRMAASY
ANQSSLPMVVDAVGVTTSSIRKSLVKDLLGYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTY
PGMSFLVTGPKDLVVSKNQVAVLGNGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCLAVSYLNIAAEKIVVQGMGL
EEFRYQVLNQLSLLRRDENWLDTIKGEVYEZ
MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGPGANDLVALLKDLPITASVRGNWDDRVLEALDGQYG
LEDPQEVQLLRMTQYLMERMDPATIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVA
VYGHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRSQYAVIEVEDGELLNIQFRKVAYDYEAELELAKSKGLPFI
EMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFLZ
MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLGDQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVE
NPLEIEGILSKTDSIHRLYKGQNGYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPT
DIESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYFIPKSEKFFLGKDRNNVELW
FEEVZ
MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEHGLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLD
IDRLVIDFLPESDYPDITIRQLLTHATDLDPPIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQ
DLDVILKDQVWKPWGMTETKFGPVELAVVTVRGVEAGIVHDPKARLLGRRAGSAGLFSTIKDLQIFLEHYLADDFARDL
NQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQKQEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEEZ
MMKKTYNHILVWGVIFYSKIVCFCFTPQEQSTVGVGTPGIQHLGRLVPLLTPFNSLWKLGEVSDIGQLCWIFLQNILNV
FLFFPLIFQLLYLFPNLRKTKKVLLFSPLVSLGIETQLILDPFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRNZ
MKIPLLTFARHKPVYVLLTLLFLALVYRDVLMTYFFFDIHAPDLAKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIP
IIIVLLGFQYIELKNKVLRIGREVSYQGLKRILTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSALPYYMVPMTSLMQASYGDVSL
MKLFTPYILYIVPYMVLEKYEDNVZ
MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPILDNSIFQSIFQVMSSAGEVVFSNLLLCVGLCIGLAK
RDKGTAALAGVTGYLVMTATIKALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFVGGSRFVPIVTS
FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPMFWYTELGGVETVAGQTVVGAQ
KIFFAQLADLAHSGLFEGTRPPAGRFSTMMFGLPAACLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFV
SPVLYVVHAFLDGVSPFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPPGLIWSVLYYIIPRWFITQFNVL
TPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVTRLRVAVKEVNQVDKALLKQIGAVDVLE
VKGGIQAIYGAKAILYKNSINEILGVDDZ
MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEITWWAFPVPTQEKTGDGVGTYEKSIIEAFEKANPDIK
VKLETIDFKSGPEKITTAIEAGTAPDVLFDAPGRIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPIS
SAPFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGTRAFISNLYSGSVTDEKVSKY
TTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNFANGQTSYTILWAPAQNGIQAICLLEASKVEVVEVPFPSDEG
KPALEYLVNGFAVFNNKDDKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSPYYN
TIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQZ
MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPDTTVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSV
FISLVTMFLVCATSSLAGYVLAKICRFYGQRILIAIPIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGV
FLMKQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIVTPINTWNDYFMQLVMLTSRNNLTISLGVATMQ
AEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKGZ
MKIMFKNFNNILLNRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFFKRELISIFSYNDYSEANLEIPKLLLNLSLFMV
GWLSVILLESDLADHYHHLIRYQSSSFFDYTRKRLVVLSKFFTQDLPVWFLGLLPLGIHFKTVALPFLLAQLMMLYLLL
SYLIALISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKGZ
MGKGEMGKGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESMHNLPVNLAG
ARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTKKDYTYKAPLAQQALPETGNKESDLLASLGL
TAFFLGLFTLGKKREQZ
MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEFRQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHP
KIQAAKNGAELADVTSEVTEEADGYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHV
RGDKGAEKLFFHGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYPRTDFASARDQGLKGNRLEEFNKIEDSIVREKD
QSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVKYAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFT
FDQLIQATLLDVIDRGNVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRAKVSDE
KRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMGALTILPLFIGFGLILYSLDVHGYLYL
PLPILGFLGLVLSVSVFYYWKLRLDNRDGVLNEAGAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYA
DKVSHLMKVHQIQVENPDINLYVAYGWHSTFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGGSIGAFZ
MKKVRKIFQKAVAGLCCISQLTAPSSIVALAETPETSPAIGKVVIKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQT
GEAIFSNIKPGTYTLTEAQPPVGYKPSTKQWTVEVEKNGRITVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDG
SEKNGQHKALNPHPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTVYEQKDKSVPLDVVILLDNSNSMSNIRNKN
ARRAERAGEATRSLIDKTSDSENRVALVTYASTIFDGTEFTVEKGVADKNGKRLNDSLPWNYDQTSFTTNTKDYSYLKL
TNDKNDIVELKNKVPTEAEDHDGNRLMYQFGATFTQKALMKADEILTQQARQNSQKVIFHITDGVPTMSYPINFNHATF
APSYQNQLNAFFSKSPNKDGILLSDFTQATSGEHTIVRGDGQSYQMFTDKVYEKGAPAAFPVKPEKYSEMKAAGYAVIG
DPINGGYIWLNWRESILAYPFNSNTAKITNHGDPTRWYYNGNIAPDGYDVFTGIGINGDPGTDEATATSFMQSISSKPE
NYTNVTDTTKILEQLNRYFHTIVTEKKSIENGTITDPMGELIDLQLGTDGRFDPADYTLTANDGSRLENGQAVGGPQND
GGLLKNAKVLYDTTEKRIRVTGLYLGTDEKVTLTYNVRLNDEFVSNKFYDTNGRTTLHPKEVEQNTVRDFPIPKIRDVR
KYPEITISKEKKLGDIEFIKVNKNDKKPLRGAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRL
FENSEPAGYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREYPRTGGIGMLPFYLIGCM
MMGGVLLYTRKHPZ
MKSINKFLTMLAALLLTASSLFSAATVFAAGTTTTSVTVHKLLATDGDMDKIANELETGNYAGNKVGVLPANAKEIAGV
MFVWTNTNNEIIDENGQTLGVNIDPQTFKLSGAMPATAMKKLTEAEGAKFNTANLPAAKYKIYEIHSLSTYVGEDGATL
TGSKAVPIEIELPLNDVVDAHVYPKNTEAKPKIDKDFKGKANPDTPRVDKDTPVNHQVGDVVEYEIVTKIPALANYATA
NWSDRMTEGLAFNKGTVKVTVDDVALEAGDYALTEVATGFDLKLTDAGLAKVNDQNAEKTVKITYSATLNDKAIVEVPE
SNDVTFNYGNNPDHGNTPKPNKPNENGDLTLTKTWVDATGAPIPAGAEATFDLVNAQTGKVVQTVTLTTDKNTVTVNGL
DKNTEYKFVERSIKGYSADYQEITTAGEIAVKNWKDENPKPLDPTEPKVVTYGKKFVKVNDKDNRLAGAEFVIANADNA
GQYLARKADKVSQEEKQLVVTTKDALDRAVAAYNALTAQQQTQQEKEKVDKAQAAYNAAVIAANNAFEWVADKDNENVV
KLVSDAQGRFEITGLLAGTYYLEETKQPAGYALLTSRQKFEVTATSYSATGQGIEYTAGSGKDDATKVVNKKITIPQTG
GIGTIIFAVAGAAIMGIAVYAYVKNNKDEDQLAZ
MTMQKMQKMISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQLPSRDGHRLQVWKLDDSYSYDDRVQIVR
DLHSWDENKLSSFKKTSFEMTFLENQIEVSHIPNGLYYYRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKTDTMTTK
VKLIKVDQDHNRLEGVGFKLVSVARDVSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIFVTNLPLGNYRFKEVEPLAGY
AVTTLDTDVQLVDHQLVTVVNQKLPRGNVDFMKVDGRTNTSLQGAMPKVMKEESGHYTPVLQNGKEVVVTSGKDGRFRV
EGLEYGTYYLWELQAPGYVQLTSPVSFTIGKDTRELVVVKNNKRPRIDVPDTGEELVYLDACCHFVVWZ
MSHIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQDDDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEP
LVVKTKWEGLVPALTSGKIDMIIAGMSPTAERRQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYL
YNLIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGFKTGEEDTAIAIGLRKNDNR
ISQINASIESKDDQVALMDRMIKEQPAEATTEETSSSFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIG
VFRTAPLSENKVIYGLQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYMTEIVRG
GILAVDKGQFEAATALGMTHNQTMRLPQVVRNILPATGNEFVINIKDTSVLNVISVVELYFSGNTVATQTYQYFQTFTI
IAVIYFVLTFTVTRILRFIERRMDMDTYTTGANQMQTEDLKZ
MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGKSTFLRSINLLETPTDGQILYHGQNVLEKGYDLTQY
REKLGMVFQSFNLFENLNVLENTIVAQTVLKRERTEAEKIAIENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMN
PDAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGVIAEEGKPEDLFTNPKEDRTK
EFLQRYLKZ
MKKYQLLFKISAVPSYLFPSLSQLTLIVQNYWQFSSQIGNLPIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYS
ILTVLVLVFQISFNVQTAKHVQSTAEGWAVLIGYSGTNFAELGIYIALFILVPLMEELIYRGLLQHAFFKHSRFGLDLL
LPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFPFLLTFLHRVLGZ
MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVTDTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTY
FQSTSEADYANNLQQAAGSYNLIFGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAK
TTKQVGFVGGIESEVISRFEAGFKGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQYAAGADIVYQVAGGTGAGVFAEA
KSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKESNFVLVSTLKQVGTTVKDISNKAERGEFPGGQVIVYSLKDKGVD
LAVTNLSEEGKKAVEDAKAKILDGSVKVPEKZ
MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTAFGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNV
GLPGQALAGWILSGWFALSHPDMPRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHA
FPKDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGFEIRAVGLNPHASEYAGISA
KRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAIGFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQV
PSELVSIVTASIIFFVSVHYLIERFVKPKKQVKGGKZ
MGVKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVF
QVQMVASRKMQEAQPRIKALREQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKT
GHFLWINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQ
TYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTKZ
MVIDPFAINELDYYLVSHPHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGPIWEGWGVPKERIIVVKPGDTIELKDMKI
HAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKAVNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNN
YGENPVGIQDKMTSIDLLRMAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQDQ
HLVEYHHPRGFDDCFEQDSNIQFKALLZ
MFLSGWLSSFANTYIHDLLGVLFPDSPFLNAFESAIAAPLVEEPLKLLSLVFVLALIPVRKLKSLFLLGIASGLGFQMI
KDIGYIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFV
ELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMTZ
MKVEPRCDVLSRMSHFFIRILIMELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGNFQRLVMTKQGRYY
DETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLNVRTWKZ
MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFLYFFFLCCFVTILFFTWDILVETQVYRQELLYGERE
AKSPLEIALAEKLEAREMELYQQRSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYT
NLVLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKWLLVVIEQIINSLKYTKEGG
LEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGRLTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFA
QVNLVLEZ
MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVP
GYGYARVSKKEREKWGCMIEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHE
SAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKLZ
MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPKFLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDE
LENQDGLDFKILFLDAADKELVARYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQ
FSDQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVMNHPESEDFYQHLLALIEPI
LPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKNWSVNEGHRDKDRRKETVNRSZ
MRKPKITVIGGGTGSPVILKSLREKDVEIAAIVTVADDGGSSGELRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYR
FSEDAGAFAGHPLGNLIIAGLSEMQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIID
NVYVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEIAYVCNIMTQRGETEHFTDS
DHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYLVQVEHDFVGLCKQVSRVISSNFLRLENGCAFHGDLIVDEL
MRIIQVKKZ
MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIAVNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAV
AVIFLLLLNQISFWVIMSLVPISVMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFI
LLVKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSISLTLINFFYSFQTVVVPIFS
IRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQIVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFN
IIFNSLYQQIPPHQLLGRVNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIYZ
MMSNKNKEILIFAILYTVLFMFDGVKLLASLMPSAIANYLVYVVLALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGW
LFLILMTVVFEFVSEMLKQFVGLDGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSII
LVGLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKSNIYYPLLVHMLSNSLSLIILAISIVKZ
LKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGSGKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKR
DVHTVFQSYALFPHMNVFENVAFPLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSLRKLSGGQRQRVAIARAIINQPRV
VLLDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQSGTPVDIYDEPINHFVATF
IGESNILPGTMIEDYLVEINGKRFEAVDGGMKPNEPVEVVIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELG
NEWMIHSTRKAIVGEEIGLDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKLZ
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGKAGVNYLYTRICQEVHSVLASKKSVKLFYSMLL
LINLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPM
TIVSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFFZ
MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGEETKVIEATEPLTILLMGVDTGNVERTETWVGRSDS
MILMTVNPKTKKTTMMSLERDILTRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDA
VGGITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQREVIQKVMELALSLNSIGH
YQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQQLQGEGELLQGVSYQIVSRAHMLEMQNLLRRSLGQEEVTQ
LETNAVLFEDLFGRAPVGDEDNZ
MKKQAYVIIALTSFLFFFSHSLLEILDFGWSIPLHDVEKTEKFVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKR
LLAGQEVVQVADPDLDASPKSLSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELEDKSDLRVSLKQNMTKLPKKIEE
HIFRILQELISNTLRHAQASCLDVYLYQTDVSLQLKVVDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQG
LAVDIRIPLLDKEZ
MIVSIISQGFVWAILGLGIFMTFRILNFFDMTTEGSFPLGGAVAVTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKG
KIPTLLSGILVMTSCHSIMLLIMGRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTICLGQAYIAT
GDNPDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLIIGEVIFKSLSLAERLVTIV
VGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTFKQTILKGAKLSKZ
MKKMKVWSVLATGVALTTLAACSGGSNSTTASSSEEKADKSQELVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQ
LADRVIAEKNNAVADMVFGIGAVDSNKIRDQKLLVQYKPKWLDKIDQSLSDWNYYNPVIVQPLVLIGAPDVKEMPKDWT
ELGSKYKGKYSISGLQGGTGRAILASILVRYLDDKGELGVSEKGWEVAKEYLICNAYTLQKGESSIVKMLDKEDPIQYG
MMWGSGALVGQKEQNVVFKVMTPEIGVPFVTEQTMVLSTSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKDL
PEDTKKFVDQVKPQNIDWEAVGKHLDEWVEKAELEYVQZ
MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTLRALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVF
QSYALFPTMTVPDNIAFGLKVKKVAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDE
PLSNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPVEIYHNSQTEFVCDFIGDIN
VLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQDPILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAA
IRSVGESVELFITPSDVLQFZ
MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSLDAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGI
LCVLFTEYFDIKGAKILKLGYMTSLIYGGVVLATGYKVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANH
TLFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAAPMIVGGKEFQTINPMIITFA
GMGNSRDLAALLAIILGIAITTILLTIMNKIEKGGNYISISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFI
VLYSFTDPVAIQTGNLTLSNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFEYGA
LLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVRAILFSVDDEMEDAARSMGASPFYT
MMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFLYHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYF
TQRPGRKVRKZ

TABLE 3
ID201 - 4106.4
ATGATAAAAAATCCTAAATTATTAACCAAGTCTTTTTTAAGAAGTTTTGCAATTCTAGGTGGTGTTGGTCTAGTCAT
TCATATAGCTATTATTTGACCTTTCCTTTTTTATTATATTCAACTGGAGGGGGAAAAGTTTAATGAGAGCGCAAGAG
TGTTTACGGAGTATTTAAAGACTAAGACATCTGATGAAATTCCAAGCTTACTCCAGTCTTATTCAAAGTCCTTGACC
ATATCTGCTCACCTTAAAAGAGATATTGTAGATAAGCGGCTCCCTCTTGTGCATGACTTGGATATTAAAGATGGAAA
GCTATCAAATTATATCGTGATGTTAGATATGTCTGTTAGTACAGCAGATGGTAAACAGGTAACCGTGCAATTTGTTC
ACGGGGTGGATGTCTACAAAGAAGCAAAGAATATTTTGCTTTTGTATCTCCCATATACATTTTTGGTTACAATTGCT
TTTTCCTTTGTTTTTTCTTATTTTTATACTAAACGCTTGCTCAATCCTCTTTTTTACATTTCAGAAGTGACTAGTAA
AATGCAAGATTTGGATGACAATATTCGTTTTGATGAAAGTAGGAAAGATGAAGTTGGTGAAGTTGGAAAACAGATTA
ATGGTATGTATGAGCACTTGTTGAAGGTTATTTATGAGTTGGAAAGTCGTAATGAGCAAATTGTAAAATTGCAAAAT
CAAAAGGTTTCCTTTGTCCGCGGAGCATCACATGAGTTGAAAACCCCTTTAGCCAGTCTTAGAATTATCCTAGAGAA
TATGCAGCATAATATTGGAGATTACAAAGATCATCCAAAATATATTGCAAAGAGTATAAATAAGATTGACCAGATGA
GCCACTTATTAGAAGAAGTACTGGAGTCTTCTAAATTCCAAGAGTGGACAGAGTGTCGTGAGACCTTGACTGTTAAG
CCAGTTTTAGTAGATATTTTATCACGTTATCAAGAATTAGCTCATTCAATAGGTGTTACAATTGAAAATCAATTGAC
AGATGCTACCAGGGTCGTCATGAGTCTTAGGGCATTGGATAAGGTTTTGACAAACCTGATTAGTAATGCAATTAAAT
ATTCAGATAAAAATGGGCGTGTAATCATATCCGAGCAAGATGGCTATCTCTCTATCAAAAATACATGTGCGCCTCTA
AGTGACCAAGAACTAGAACATTTATTTGATATATTCTATCATTCTCAAATCGTGACAGATAAGGATGAAAGTTCCGG
TTTGGGTCTTTACATTGTGAATAATATTTTAGAAAGCTATCAAATGGATTATAGTTTTCTCCCTTATGAACACGGTA
TGAATTTAAGATTAGCTTGTAG
MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGEKFNESARVFTEYLKTKTSDEIPSLLQSYSKSLT
ISAHLKRDIVDKRLPLVHDLDIKDGKLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIA
FSFVFSYFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYELESRNEQIVKLQN
QKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSINKIDQMSHLLEEVLESSKFQEWTECRETLTVK
PVLVDILSRYQELAHSIGVTIENQLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPL
SDQELEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISLZ
ID202 - 4106.9
ATGGATAAAATTATTAAAACTATATCAGAAAGCGGAGCCTTTCGTGCTTTTGTCCTTGATAGCACTGAAACCGTCCG
CACTGCTCAAGAAAAACATCAAACCCAAGCTAGCTCAACTGTAGCGCTTGGTCGAACTCTTATCGCTAGCCAGATTC
TCGCAGCCAATGAAAAAGGAAATACCAAACTTACAGTTAAGGTGTTGGGATCTAGCTCTCTAGGTGCTATTATCACC
GTCGCTGATACCAAGGGGAACGTCAAAGGCTATGTTCAAAATCCTGGTGTTGACATCAAAAAGACTGCGACTGGTGA
AGTCCTAGTCGGACCTTTTGTTGGAAATGGTCAATTCCTCGTTATCACAGACTACGGTACTGGAAATCCTTACAACT
CTATAACTCCCCTCATCTCTGGAGAAATCGGTGAAGACCTTGCCTTTTACCTTACTGAAAGCCAACAAACGCCTTCA
GCGGTCGGCCTCAATGTCCTTTTGGACGAGGAAGACAAGGTCAAGGTTGCAGGTGGTTTCCTAGTTCAAGTCTTGCC
AGGAGCCAAGAAAGAAGAGATTGCTCGCTTTGAAAAACGCATCCAAGAAATGCCAGCTATCTCTACTCTTCTCGAAA
GCGACGACCATATCGAAGCCCTCCTCAAGGCTATCTACGGGGACGAAGCCTACAAGCGTCTTTCTGAAGAAGAAATC
CGTTTCCAATGTGACTGTAGCCATGAACGCTTTATGAACGCTCTTGCCAGCCTTCCAAGCTCAGACTTACAGGAAAT
GAAAGAGGAAGACCACGGGGCAGAAATCACTTGTCAATTCTGCCAAACTACTTACAACTTTGATGAAAAGGACCTGG
AGGAACTCATTCGTGACAAATCTTAA
MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNTKLTVKVLGSSSLGAIIT
VADTKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPS
AVGLNVLLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEI
RFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKSZ
ID203 - 4115
ATGAAATCAATAACTAAAAAGATTAAAGCAACTCTTGCAGGAGTAGCTGCCTTGTTTGCAGTATTTGCTCCATCATT
TGTATCTGCTCAAGAATCATCAACTTACACTGTTAAAGAAGGTGATACACTTTCAGAAATCGCTGAAACTCACAACA
CAACAGTTGAAAAATTGGCAGAAAACAACCACATTGATAACATTCATTTGATTTATGTTGATCAAGAGTTGGTTATC
GATGGCCCTGTAGCGCCTGTTGCAACACCAGCGCCAGCTACTTATGCGGCACCAGCCGCTCAAGATGAAACTGTTTC
AGCTCCAGTAGCAGAAACTCCAGTAGTAAGTGAAACAGTTGTTTCAACTGTAAGCGGATCTGAAGCAGAAGCCAAAG
AATGGATCGCTCAAAAAGAATCAGGTGGTAGTATACAGCTACAAATGGACGTTATATCGGACGTTACCAATTAA
MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHLIYVDQELVI
DGPVAPVATPAPATYAAPAAQDETVSAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSIQLQMDVISDVTNZ
ID204 - 4117.1
ATGAATTTAGGAGAATTTTGGTACAATAAAATAAATAAGAACAGAGGAAGAAGGTTAATGAAGAAAGTAAGATTTAT
TTTTTTAGCTCTGCTATTTTTCTTAGCTAGTCCAGAGGGTGCAATGGCTAGTGATGGTACTTGGCAAGGAAAACAGT
ATCTGAAAGAAGATGGCAGTCAAGCAGCAAATGAGTGGGTTTTTGATACTCATTATCAATCTTGGTTCTATATAAAA
GCAGATGCTAACTATGCTGAAAATGAATGGCTAAAGCAAGGTGACGACTATTTTTACCTCAAATCTGGTGGCTATAT
GGCCAAATCAGAATGGGTAGAAGACAAGGGAGCCTTTTATTATCTTGACCAAGATGGAAAGATGAAAAGAAATGCTT
GGGTAGGAACTTCCTATGTTGGTGCAACAGGTGCCAAAGTAATAGAAGACTGGGTCTATGATTCTCAATACGATGCT
TGGTTTTATATCAAAGCAGATGGACAGCACGCAGAGAAAGAATGGCTCCAAATTAAAGGGAAGGACTATTATTTCAA
ATCCGGTGGTTATCTACTGACAAGTCAGTGGATTAATCAAGCTTATGTGAATGCTAGTGGTGCCAAAGTACAGCAAG
GTTGGCTTTTTGACAAACAATACCAATCTTGGTTTTACATCAAAGAAAATGGAAACTATGCTGATAAAGAATGGATT
TTCGAGAATGGTCACTATTATTATCTAAAATCCGGTGGCTACATGGCAGCCAATGAATGGATTTGGGATAAGGAATC
TTGGTTTTATCTCAAATTTGATGGGAAAATGGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCTTGGTACT
ACTTCAAATCCGGTGGTTACATGACAGCCAATGAATGGATTTGGGATAAGGAATCTTGGTTTTATCTCAAATCTGAT
GGGAAAATAGCTGAAAAAGAATGGGTCTACGATTCTCATAGTCAAGCTTGGTACTACTTCAAATCCGGTGGTTACAT
GACAGCCAATGAATGGATTTGGGATAAGGAATCTTGGTTTTACCTCAAATCTGATGGGAAAATAGCTGAAAAAGAAT
GGGTCTACGATTCTCATAGTCAAGCTTGGTACTACTTCAAATCTGGTGGCTACATGGCGAAAAATGAGACAGTAGAT
GGTTATCAGCTTGGAAGCGATGGTAAATGGCTTGGAGGAAAAACTACAAATGAAAATGCTGCTTACTATCAAGTAGT
GCCTGTTACAGCCAATGTTTATGATTCAGATGGTGAAAAGCTTTCCTATATATCGCAAGGTAGTGTCGTATGGCTAG
ATAAGGATAGAAAAAGTGATGACAAGCGCTTGGCTATTACTATTTCTGGTTTGTCAGGCTATATGAAAACAGAAGAT
TTACAAGCGCTAGATGCTAGTAAGGACTTTATCCCTTATTATGAGAGTGATGGCCACCGTTTTTATCACTATGTGGC
TCAGAATGCTAGTATCCCAGTAGCTTCTCATCTTTCTGATATGGAAGTAGGCAAGAAATATTATTCGGCAGATGGCC
TGCATTTTGATGGTTTTAAGCTTGAGAATCCCTTCCTTTTCAAAGATTTAACAGAGGCTACAAACTACAGTGCTGAA
GAATTGGATAAGGTATTTAGTTTGCTAAACATTAACAATAGCCTTTTGGAGAACAAGGGCGCTACTTTTAAGGAAGC
CGAAGAACATTACCATATCAATGCTCTTTATCTCCTTGCCCATAGTGCCCTAGAAAGTAACTGGGGAAGAAGTAAAA
TTGCCAAAGATAAGAATAATTTCTTTGGCATTACAGCCTATGATACGACCCCTTACCTTTCTGCTAAGACATTTGAT
GATGTGGATAAGGGAATTTTAGGTGCAACCAAGTGGATTAAGGAAAATTATATCGATAGGGGAAGAACTTTCCTTGG
AAACAAGGCTTCTGGTATGAATGTGGAATATGCTTCAGACCCTTATTGGGGCGAAAAAATTGCTAGTGTGATGATGA
AAATCAATGAGAAGCTAGGTGGCAAAGATTAG
MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASDGTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIK
ADANYAENEWLKQGDDYFYLKSGGYMAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDA
WFYIKADGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFYIKENGNYADKEWI
FENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSD
GKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMAKNETVD
GYQLGSDGKWLGGKTTNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTED
LQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAE
ELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFD
DVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKDZ
ID205 - 4118.1
ATGAAAAAATTAGGTACATTACTCGTTCTCTTTCTTTCTGCAATCATTCTTGTAGCATGTGCTAGCGGAAAAAAAGA
TACAACTTCTGGTCAAAAACTAAAAGTTGTTGCTACAAACTCAATCATCGCTGATATTACTAAAAATATTGCTGGTG
ACAAAATTGACCTTCATAGTATCGTTCCGATTGGGCAAGACCCACACGAATACGAACCACTTCCTGAAGACGTTAAG
AAAACTTCTGAGGCTAATTTGATTTTCTATAACGGTATCAACCTTGAAACAGGTGGCAATGCTTGGTTTACAAAATT
GGTAGAAAATGCCAAGAAAACTGAAAACAAAGACTACTTCGCAGTCAGCGACGGCGTTGATGTTATCTACCTTGAAG
GTCAAAATGAAAAAGGAAAAGAAGACCCACACGCTTGGCTTAACCTTGAAAACGGTATTATTTTTGCTAAAAATATC
GCCAAACAATTGAGCGCCAAAGACCCTAACAATAAAGAATTCTATGAAAAAAATCTCAAAGAATATACTGATAAGTT
AGACAAACTTGATAAAGAAAGTAAGGATAAATTTAATAAGATCCCTGCTGAAAAGAAACTCATTGTAACCAGCGAAG
GAGCATTCAAATACTTCTCTAAAGCCTATGGTGTCCCAAGTGCTTACATCTGGGAAATCAATACTGAAGAAGAAGGA
ACTCCTGAACAAATCAAGACCTTGGTTGAAAAACTTCGCCAAACAAAAGTTCCATCACTCTTTGTAGAATCAAGTGT
GGATGACCGTCCAATGAAAACTGTTTCTCAAGACACAAACATCCCAATCTACGCTCAAATCTTTACTGACTCTATCG
CAGAACAAGGTAAAGAAGGCGACAGCTACTACAGCATGATGAAATACAACCTTGACAAGATTGCTGAAGGATTGGCA
AAATAA
MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVK
KTSEANLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLEWGIIFAKNI
AKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEG
TPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLA
KZ
ID206 - 4119.1
ATGGAATGGTATAAAAAAATCGGACTTCTTGCAACTACAGGTTTAGCTTTGTTTGGGCTCGGCGCTTGCTCCAACTA
TGGTAAATCTGCGGATGGCACAGTCACCATCGAGTATTTCAACCAGAAAAAAGAAATGACCAAAACCTTGGAAGAAA
TCACTCGTGATTTTGAGAAGGAAAACCCTAAGATCAAGGTCAAAGTCGTCAATGTACCAAATGCTGGTGAAGTATTG
AAGACACGCGTTCTCGCAGGAGATGTGCCTGATGTGGTCAATATTTACCCACAGTCCATCGAACTGCAAGAATGGGC
AAAAGCAGGTGTTTTTGAAGATTTGACCAACAAAGACTACCTCAAACGCGTGAAAAATGGCTACGCTGAAAAATATG
CTGTAAACGAAAAAGTTTACAACGTTCCTTTTACAGCTAATGCTTATGGAATTTACTACAACAAAGATAAATTCGAA
GAACTGGGCTTGAAGGTTCCTGAAACCTGGGATGAATTTGAACAGTTAGTCAAAGATATCGTTGCTAAAGGACAAAC
ACCATTTGGAATTGCAGGTGCAGATGCTTGGACACTCAATGGTTACAATCAATTAGCCTTTGCGACAGCAACAGGTG
GAGGAAAAGAAGCAAATCAATACCTTCGTTATTCTCAACCAAATGCCATTAAATTGTCGGATCCGATTATGAAAGAT
GATATCAAGGTCATGGACATCCTTCGCATCAATGGATCTAAGCAAAAGAACTGGGAAGGTGCTGGCTATACCGATGT
TATCGGAGCCTTCCCACGTGGGGATGTCCTCATGACACCAAATGGGTCTTGGGCGATCACAGCGATTAATGAACAAA
AACCGAACTTTAAGATTGGGACCTTCATGATTCCAGGAAAAGAAAAAGGACAAAGCTTAACCGTTGGTGCGGGAGAC
TTGGCATGGTCTATCTCAGCCACCACCAAACATCCAAAAGAAGCCAATGCCTTTGTGGAATATATGACCCGTCCAGA
AGTCATGCAAAAATACTACCATGTCGACCGATCTCCAACAGCGATCGAAGGGGTCAAACAAGCAGGAGAAGATTCAC
CGCTTGCTGGTATGACCGAATATGCCTTTACGGATCGTCACTTGGTCTGGTTGCAACAATACTGGACCAGTGAAGCA
GACTTCCATACCTTGACCATGAACTATGTCTTGACCGCTGATAAACAAGGCATGGTCAATGATTTGAATGCCTTCTT
TAACCCGATGAAAGCGGATGTGGATTAG
MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKEMTKTLEEITRDFEKENPKIKVKVVNVPNAGEVL
KTRVLAGDVPDVVNIYPQSIELQEWAKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFE
ELGLKVPETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQPNAIKLSDPIMKD
DIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAITAINEQKPNFKIGTFMIPGKEKGQSLTVGAGD
LAWSISATTKHPKEANAFVEYMTRPEVMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEA
DFHTLTMNYVLTGDKQGMVNDLNAFFNPMKADVDZ
ID207 - 4123.1
ATGAAGAAAATCAAACCGCATGGACCGTTACCAAGTCAGACTCAGCTAGCTTATCTGGGAGATGAACTAGCAGCTTT
TATCCACTTCGGTCCTAATACCTTTTATGACCAAGAATGGGGGACTCGACAGGAGGATCCTGAGCGCTTTAACCCGA
GTCAGTTGGATGCGCGTGAGTGGGTTCGTGTGCTCAAGGAAACGGGCTTCAAAAAGTTGATTTTGGTGGTCAAGCAC
CACGATGGCTTTGTCCTTTATCCGACAGCTCACACAGATTATTCGGTTAAGGTCAGTCCTTGGAGGACAGGAAAGGG
CGACTTGCTCCTTGAAGTATCCCAAGCTGCCACAGAGTTTGATATGGATATGGGGGTCTACCTGTCACCGTGGGATG
CCCATAGTCCCCTCTATCATGTGGACCGAGAAGCGCACTACAATGCCTATTATCTGGCTCAGTTGAAGGAAATCTTA
TCAAATCCTAACTATGGGAATGCTGGTAAGTTCCCTGAGGTTTGGATGGATGGTGCCAGAGGAGAGGGCGCGCAAAA
GGTTAATTATGAATTTGAAAAATGGTTTGAAACCATTCGTGACCTGCAGGGCGATTGCTTGATTTTTTCAACAGAAG
GCACCAGTATCCGCTGGATGGGCAATGAACGAGGGTATCCAGGTGATCCACTGTGGCAAAAGGTGAATCCTGATAAA
CTAGGAACAGAAGCAGAGCTGAACTATCTTCAGCACGCGGATCCCTCGGGCACGATTTTTTCAATCGGAGAGGCAGA
TGTTTCCATCCGTCCAGGCTGGTTCTACCATGAGGATCAGGATCCTAAGTCTCTCGAGGAGTTGGTCGAAATCTACT
TTCACTCAGTAGGGCGAGGAACTCCACTCTTGCTTAATATTCCGCCGAATCAAGCTGGGCTCTTTGATGCAAAGGAT
ATTGAACGACTTTATGAATTTGCGACCTATCGCAATCAGCTCTATAAAGAAGATTTGGCTCTGGGAGCTGAGGTATC
TGGTCCAGCTCTTTCCGCAGACTTTGCTTGTCGCCATTTCACAGACGGCCTTGAGACCAGCTCTTGGGCAAGCGATG
CAGACTTGCCCATCCAGTTAGAACTCGACTTAGGTTCTCCTAAAACTTTTGATGTAATTGAGTTAAGAGAAGATTTG
AAGCTAGGGCAACGAATCGCTGCTTTTCATGTGCAAGTAGAGGTGGATGGTGTCTGGCAGGAGTTTGGTTCGGGTCA
TACTGTTGGTTACAAACGTCTCTTACGAGGAGCAGTTGTTGAGGCACAGAAGATACGTGTAGTCATTACAGAATCAC
AGGCTTTGCCTTTGTTGACCAAGATTTCCCTTTATAAAACTCCTGGATTATCAAAAAAAGAAGTTGTTCAGGAACTA
GCATTTGCAGAAAAAAGCCTAGCTGTGGCAAAGGGAGAAAATGCCTATTTTACAGTTAAGCGCAGAGAATGTAGTGG
TCCTTTAGAAGCTAAGATTTCGATTCAACCGGGGACAGGTGTCCATGCTGTCGCCTATCAGGATGAGATTCAAGTCC
TTGCGTTTCAAACTGGTGAGACTGAAAAAAGTCTGACGCTACCAACCTTGTATTTCGCAGGAGATAAAACCTTGGAT
TTCTATCTGAACCTAACGGTGGATGGTCAGCTTGTGGATCAACTTCAAGTCCAAGTTTCATAA
MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKH
HDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEIL
SNPNYGNAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGYAGDPLWQKVNPDK
LGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYMEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKD
IERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDL
KLGQRIAAFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTPGLSKKEVVQEL
AFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQDEIQVLAFQTGETEKSLTLPTLYFAGDKTLD
FYLNLTVDGQLVDQLQVQVSZ
ID208 - 4125.12
ATGCTTGAAAGACTGAAAAGAATACATTATATGTTTTGGATCAGTTTAATTTTTATGATTTTCCCCATCCTGTCTGT
AGTGACTGGGTGGCTTTCTGCCTGGCATTTATTGATTGATATTCTATTTGTAGTGGCATATTTGGGTGTTTTAACAA
CTAAGAGCCAGCGCCTATCTTGGCTATATTGGGGCCTCATGCTGACTTATGTAGTTGGGAATACTGCCTTTGTTGCT
GTTAATTATATCTGGTTTTTCTTTTTCCTATCCAATCTCTTAAGTTATCATTTCAGCGTACGTAGTTTAAAGTCTTT
ACATGTCTGGACTTTTCTTCTTGCTCAAGTCCTTGTTGTGGGGCAACTGTTGATTTTTCAGAGAATCGAAGTTGAGT
TTCTATTCTATCTACTTGTAATTCTTACTTTTGTCGATTTAATGACTTTTGGATTGGTTCGGATTCGTATTGTCGAG
GATTTGAAAGAAGCTCAGGTCAAGCAAAATGCTCAGATAAATCTATTGCTTGCTGAAAATGAACGTAGTCGTATCGG
TCAGGATTTGCATGATAGTCTGGGACATACCTTTGCTATGCTGAGTGTCAAGACAGATTTAGCCTTGCAGTTATTTC
AGATGGAGGCTTATCCACAGGTGGAAAAGGAATTAAAAGAAATTCACCAGATCAGCAAGGATCCATGA
MLERLKRIHYMFWISLIFMIFPILSVVTGWLSAWHLLIDILFVVAYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVA
VNYIWFFFFLSNLLSYHFSVRSLKSLHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILTFVDLMTFGLVRIRIVE
DLKEAQVKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKDLALQLFQMEAYPQVEKELKEIHQISKDPZ
ID209 - 4126.3
ATGAATGATAAGTTAAAAATCTTCTTGTTGCTAGGAGTATTTTTTCTAGCCATAACCCGTTTCTATGTTCTATTGAT
ACGAAATGCAGGGCAGACAGATGCCTCGCAAATTGAAAAGGCGGCAGTTAGCCAAGGAGGAAAAGCAGTGAAAAAAA
CAGAAATTAGTAAAGACGCAGACTTGCACGAAATTTATCTAGCTGGAGGTTGTTTCTGGGGAGTGGAGGAATATTTC
TCACGTGTTCCCGGGGTGACGGATGCCGTTTCAGGCTATGCAAATGGTAGAGGAGAAACAACCAAGTACGAATTGAT
TAACCAACAGGTCATGCAGAAACCGTCCATGTCACCTATGATGCCAAGCAAATTTCTCTCAAGGAAAATCCTGCTTC
ACTATTTCCGCATTATCAATCCAACCAGCAAAAATAAACAAGGAAATGATGTGGGGACCCAGTACCGTACTGGTGTT
TATTACACAGATGACAAGGATTTGGAAGTGATTAACCAAGTCTTTGATGAGGTGGCTAAGAAATACGATCAACCTCT
AGCAGTTGAAAAGGAAAACTTGAAGAATTTTGTGGTGGCTGAGGATTACCATCAAGACTATCTCAAGAAAAATCCAA
ATGGCTACTGCCATATCAATGTTAATCAGGCGGCCTATCCTGTCATTGATGCCAGCAAATATCCAAAACCAAGTCAT
GAGGAATTGAAAAAGACCCTGTCACCTGAGGAGTATGCAGTTACCCAGGAAAATCAAACAGAACGAGCTTTCTCAAA
CCGTTACTGGGATAAATTTGAATCCGGTATCTATGTGGATATAGCAACTGGGGAACCTCTCTTTTCATCAAAAGACA
AATTTGAGTCTGGTTGTGGCTGGCCTAGTTTTACCCAACCCATCAGTCCAGATGTTGTCACCTACAAGGAAGATAAG
TCCTACAATATGACGCGTATGGAAGTGCGGAGCCGAGTAGGAGATTCTCACCTTGGGCATGTCTTTACGGATGGTCC
ACAGGACAAGGGCGGCTTACGTTACTGTATCAATAGCCTCTCTATCCGCTTTATTCCCAAAGACCAAATGGAAGAAA
AAGgcTACGCTTATTTACTAGATTATGTTGATTAA
MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQGGKAVKKTEISKDADLHEIYLAGGCFWGVEEYF
SRVPGVTDAVSGYANGRGETTKYELINQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGV
YYTDDKDLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAYPVIDASKYPKPSD
EELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEPLFSSKDKFESGCCWPSFTQPISPDVVTYKEDK
SYNMTRMEVRSRVGDSHLGHVFTDGPQDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVDZ
ID210 - 4127.1
ATGAAAAAGAAATGGATGTATTATGCTGCTTGTTCTTCTAATGAATCTGCCGATGACAGTTCATCTGATAAAGGAGA
CGGCGGTTCGCTAGTCGTTTATTCACCAAACTCAGAGGGCTTAATTGGAGCAACTATTCCTGCCTTTGAAGAAAAAT
ATGGTATCAAAGTAGAACTGATTCAAGCTGGTACTGGAGAACTTTTCAAAAAACTAGAGTCAGAAAAAGAAGTTCCT
GTAGCTGATGTTATCTTTGOTGGTTCTTATACACAATATACTACCCACGGAGAACTCTTTGAAAACTATACTTCAAA
AGAAAATGATAATGTTATCAAAGAATATCAAAACACAACTGGCTACTCTACTCCTTATACACTAGATGGTAGTGTTT
TAATCGTCAACCCTGATTTAACTAAAGGCATGAACATCGAAGGATATAACGATCTTTTCAAACCTGAACTAAAACGA
AAAATCGCAACTGCTGACCCACCAAACTCTTCTACCGCCTTTGCTCAATTAACAAATATGCTACAAGCTCAAGGTGG
TTACAAAGATGATAAGGCTTGGTCTTATGTAAAAGATCTTTTCACACTTATTGATGGTAAAATCGGTTCAAGTTCAT
CTAGTGTCTATAAAGTAGTCCCTGATGGAGAAATGGCTGTTGGTCTCTCTTATGAAGATCCAGCAGTTAAACTCTTA
AATGACGGAGCTAACATTAAGGTAGTCTATCCAAAAGAAGGAACCGTCTTCCTACCTGCTAGTGCTGCTATCGTTAA
AAAATCTAAAAATATGGAAAATGCCAAGAAATTTATCGATTTTATTATCTCTCAAGAAGTACAAGATACACTTGGTA
CAACCACTACTAACCGTCCTGTTCGTAAAAATGCTAAAACAAGCGAAAACATGAAACCAATTGACAAAATCAAAACA
CTCACTGAAGATTATGATTATGTCATCAAGAATAAATCAGATATCGTTAAGAAATACAACGAAGTCTTTACAGATAT
CCAATCTAAACAGTAA
MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGATIPAFEEKYGIKVELIQAGTGELFKKLESEKEVP
VADVIFGGSYTQYTTHGELFENYTSKENDNVIKEYQNTTGYSTPYTLDGSVLIVNPDLTKGMINEGYNDLFKPELKG
KIATADPANSSSAFAQLTNMLQAQGGYKDDKAWSYVKDLFTLIDGKIGSSSSSVYKVVADGEMAVGLSYEDPAVKLL
NDGANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKT
LTEDYDYVIKNKSDIVKKYNEVFTDIQSKQZ
ID211 - 4127.2
ATGAGTGAGATCAAAATTATTAACGCCAAAAAAATCTACCACGATGTCCCTGTTATTGAGAATTTGAACATTACAAT
TCCAAAAGGAAGTCTCTTTACCCTTCTTGGAGCTTCAGGATGTGGGAAAACGACCCTTCTTCGTATGATTGCAGGTT
TCAACAGTATCGAAGGTGGAGAATTTTACTTCGATGATACAAAAATCAATAATATGGAACCCAGCAAACGCAATATC
GGGATGGTTTTCCAAAACTACGCTATTTTCCCACATTTGACTGTCCGAGACAACGTTGCTTTTGGTCTTATGCAAAA
GAAGGTTCCAAAAGAAGAATTGATTCAACAGACCAACAAGTATCTTGAACTCATGCAAATTGCTCAATATGCGGATC
GAAAGCCCGATAAACTCAGTGGTGGACAACAACAACGTGTCACCTTGGCATGCGCCTTAGCGGTTAATCCAAGTGTT
CTCCTCATGGACGAGCCACTTAGTAATCTGGAGGCCAAACTTCGCTTGGATATGCGTCAAGCCATCCGAGAAATCCA
ACACGAAGTGGGAATTACAACTGTTTATGTAACCCACGACCAAGAAGAAGCCATGGCTATTTCAGACCAAATTGCTG
TTATGAAAGATGGGGTGATCCAACAAATCGGCCGACCAAAAGAACTCTATCATAAACCAGCTAATGAGTTTGTGGCA
ACCTTTATCGGACGCACAAATATTATCCCTGCCAATCTTGAAAAACGGAGCGACGGCGCTTATATCGTCTTTTCAGA
TGGCTATGCCCTTCGAATGCCAGCTCTTGATCAGGTTGAGGAGCAAGCTATTCATGTAAGCATTCGTCCCGAAGAGT
TTATCAAAGATGAATCTGGAGATATTGAAGGAACTATTAGAGATAGCGTCTATCTTGGACTAAATACGGATTATTTC
ATTGAGACAGGTTTTGCCTCAAAAATTCAAGTTAGTGAAGAATCAACTTTTGAAGAAGATCTACAAAAAGGCAATCG
TATTCGTCTACGAATCAATACGCAAAAATTAAACATCTTTTCTGCAGATGGTTCCCAAAACCTGATAAAAGGAGTCA
ACCATGGAACGTAA
MSEIKIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCCGKTTLLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNI
GMVFQNYAIFPHLTVRDNVAFGLMQKKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSV
LLMDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRPKELYHKPANEFVA
TFIGRTNIIPANLEKRSDGAYIVFSDGYALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTIRDSVYLGLNTDYF
IETGFASKIQVSEESTFEEDLQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGTZ
ID212 - 4136.1
ATGAAGAAAAAATTATTGGCAGGTGCCATCACACTATTATCAGTAGCAACTTTAGCAGCTTGTTCGAAAGGGTCAGA
AGGTGCAGACCTTATCAGCATGAAAGGGGATGTCATTACAGAACATCAATTTTATGAGCAAGTGAAAAGCAACCCTT
CAGCCCAACAAGTCTTGTTAAATATGACCATCCAAAAAGTTTTTGAAAAACAATATGGCTCAGAGCTTGATGATAAA
GAGGTTGATGATACTATTGCCGAAGAAAAAAAACAATATGGCGAAAACTACCAACGTGTCTTGTCACAAGCAGGTAT
GACTCTTGAAACACGTAAAGCTCAAATTCGTACAAGTAAATTAGTTGAGTTGGCAGTTAAGAAGGTAGCAGAAGCTG
AATTGACAGATGAAGCCTATAAGAAAGCCTTTGATGAGTACACTCCAGATGTAACGGCTCAAATCATCCGTCTTAAT
AATGAAGATAAGGCCAAAGAAGTTCTCGAAAAAGCCAAGGCAGAAGGTGCTGATTTTGCTCAATTAGCCAAAGATAA
TTCAACTGATGAAAAAACAAAAGAAAATGGTGGAGAAATTACCTTTGATTCTGCTTCAACAGAAGTACCTGAGCAAG
TCAAAAAAGCCGCTTTCGCTTTAGATGTGGATGGTGTTTCTGATGTGATTACAGCAACTGGCACACAAGCCTACAGT
AGCCAATATTACATTGTAAAACTCACTAAGAAAACAGAAAAATCATCTAATATTGATGACTACAAAGAAAAATTAAA
AACTGTTATCTTGACTCAAAAACAAAATGATTCAACATTTGTTCAAAGCATTATCGGAAAAGAATTGCAAGCAGCCA
ATATCAAGGTTAAGGACCAAGCCTTCCAAAATATCTTTACCCAATATATCGGTGGTGGAGATTCAAGCTCAAGCAGT
AGTACATCAAACGAATAG
MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDK
EVDDTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLN
NEDKAKEVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYS
SQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIGGGDSSSSS
STSNEZ
ID213 - 4137.3
ATGAAAAAAAATATTAAACAATATGTAACCTTAGGTACTGTAGTGGTATTATCAGCATTTGTTGCTAACTCAGTTGC
AGCTCAGGAGACTGAAACTTCTGAAGTATCAACACCAAAGTTGGTGCAACCTGTTGCACCAACGACTCCGATTTCGG
AAGTACAACCTACATCGGATAACTCTTCGGAAGTTACTGTACAACCTCGAACAGTTGAAACTACTGTTAAGGATCCA
TCTTCTACAGCGGAAGAAACTCCTGTCTTAGAAAAAAATAATGTTACTTTAACAGGGGGCGGAGAAAATGTTACTAA
AGAGTTAAAGGATAAATTTACTAGCGGTGACTTTACTGTAGTGATTAAGTACAATCAGTCAAGTGAGAAAGGCTTAC
AAGCTCTGTTTGGAATATCTAATTCCAAACCCGGTCAACAAAATAGTTATGTAGATGTGTTCCTTAGAGACAATGGT
GAGTTGGGGATGGAAGCGCGTGATACTTCTTCCAATAAAAATAACCTAGTATCCAGACCTGCTTCAGTTTGGGGTAA
GTACAAACAAGAGGCTGTGACTAACACTGTTGCAGTAGTAGCAGATTCAGTCAAAAAAACATATTCTTTATACGCAA
ATGGTACAAAAGTAGTAGAAAAGAAAGTGGATAATTTCCTTAAACATCAAGGATATTAAGGTATTGATTACTATATG
CTTGGGGGAGTGAAACGTGCAGGAAAAACGGCGTTTGGTTTTAACGGAACACTAGAAAATATCAAATTCTTTAATAG
TGCATTGGATGAAGAAACTGTTAAAAAGATGACAACAAACGCTGTTACTGGACATTTAATTTATACGGCTAATGATA
CAACAGGTTCTAACTATTTCCGTATTCCAGTTCTGTATACTTTTAGCAATGGTCGGGTATTTTCAAGCATTGACGCT
CGTTACGGTGGAACTCATGATTTCTTGAATAAAATTAATATTGCTACAAGTTATAGTGATGATAATGGTAAGACATG
GACTAAACCAAAATTAACATTGGCATTCGATGATTTTGCGCCAGTACCATTAGAATGGCCTCGTGAAGTTGGTGGAC
GTGACTTACAAATCAGCGGTGGTGCAACCTATATTGACTCTGTTATTGTTGAAAAAAAGAACAAACAAGTACTCATG
TTTGCTGATGTGATGCCTGCTGGAGTAAGTTTTAGAGAAGCAACTAGAAAAGATTCAGGTTATAAACAAATTGATGG
TAATTATTACCTTAAATTAAGGAAACAAGGTGATACTGATTACAATTATACTATTCGTGAGAATGGTACTGTATACG
ACGATCGTACCAACAGACCAACTGAATTTTCAGTAGATAAAAATTTCGGTATTAAACAAAATGGTAATTATTTGACG
GTAGAGCGG
MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPVAPTTPISEVQPTSDNSSEVTVQPRTVETTVKDP
SSTAEETPVLEKNNVTLTGGGENVTKELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNG
ELGMEARDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNFLNIKDIKGIDYYM
LGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHLIYTANDTTGSNYFRIPVLYTFSNGRVFSSIDA
RYGGTHDFLNKINIATSYSDDNGKTWTKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLM
FADVMPAGVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDKNFGIKQNGNYLT
VER
ID214 - 4185
ATGAAAAAATTTAGCCTATTACTAGCTATCCTACCATTTTTGGTTGCCTGTGAGAATCAAGCTACACCCAAAGAGAC
TAGCGCTCAAAAGACAATCGTCCTTGCTACAGCTGGCGACGTGCCACCATTTGACTACGAAGACAAGGGCAATCTGA
CAGGCTTTGATATCGAAGTTTTAAAGGCAGTAGATGAAAAACTCAGCGACTACGAGATTCAATTCCAAAGAACCGCC
TGGGAGAGCATCTTCCCAGGACTTGATTCTGGTCACTATCAGGCTGCGGCCAATAACTTGAGTTACACAAAAGAGCG
TGCTGAAAAATACCTTTACTCGCTTCCAATTTCCAACAATCCCCTCGTCCTTGTCAGCAACAAGAAAAATCCTTTGA
CTTCTCTTGACCAGATCGCTGGTAAAACAACACAAGAGGATACCGGAACTTCTAACGCTCAATTCATCAATAACTGG
AATCAGAAACACACTGATAATCCCGCTACAATTAATTTTTCTGGTGAGGATATTGGTAAACGAATCCTAGACCTTGC
TAACGGAGAGTTTGATTTCCTAGTTTTTGACAAGGTATCCGTTCAAAAGATTATCAAGGACCGTGGTTTAGACCTCT
CAGTCGTTGATTTACCTTCTGCAGATAGCCCCAGCAATTATATCATTTTCTCAAGCGACCAAAAAGAGTTTAAAGAG
CAATTTGATAAAGCGCTCAAAGAACTCTATCAAGACGGAACCCTTGAAAAACTCAGCAATACCTATCTAGGTGGTTC
TACCTCCCAGATCAATCTCAGTTACAATAA
MKKPSLLLAILPFLVACENQATPKETSAQKTIVLATAGDVPPFDYEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTA
WESIFPGLDSGHYQAAANNLSYTKERAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNW
NQKHTDNPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSNYIIFSSDQKEFKE
QFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQZ
ID215 - 4211.1
ATGAAAAAAAATAGTTTATATATCATATCCTCACTCTTTTTTGCTTGTGTCTTATTTGTCTATGCTACGGCGACGAA
TTTTCAAAACAGTACCAGTGCTAGGCAGGTAAAAACGGAAACCTATACTAATACAGTAACAAATGTCCCTATTGACA
TACGCTATAATAGTGATAAGTATTTTATTAGCGGTTTTGCTTCAGAAGTATCAGTGGTCTTGACTGGTGCAAATCGC
CTATCGCTAGCTAGTGAAATGCAAGAAAGTACACGTAAATTCAAGGTTACTGCTGACCTAACAGATGCCGGTGTTGG
AACGATTGAAGTTCCTTTGAGCATTGAAGATTTACCCAATGGGCTGACCGCTGTGGCGACTCCGCAAAAAATTACAG
TCAAGATTGGTAAGAAGGCTCAGAAGGATAAGGTAAAGATTGTACCAGAGATTGACCCTAGTCAAATTGATAGTCGG
GTACAAATTGAAAATGTCATGGTGTCAGATAAAGAAGTGTCTATTACGAGTGACCAAGAGACATTGGATAGAATTGA
TAAGATTATCGCTGTTTTGCCAACTAGCGAACGTATAACAGGTAATTACAGTGGTTCAGTACCTTTGCAGGCAATCG
ACCGCAATGGTGTTGTCTTACCGGCAGTTATCACTCCGTTTGATACAATAATGAAGGTGACTACAAAACCAGTAGCA
CCAAGTTCAAGCACATCAAATTCAAGTACAAGCAGTTCATCGGAGACATCTTCGTCAACGAAAGCAACTAGTTCAAA
AACGAATTAA
MKKNSLYIISSLFFACVLFVYATATNFQWSTSARQVKTETYTNTVTNVPIDIRYNSDKYFISGFASEVSVVLTGANR
LSLASEMQESTRKFKVTADLTDAGVGTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSR
VQIENVMVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITPFDTIMKVTTKPVA
PSSSTSNSSTSSSSETSSSTKATSSKTNZ
ID216 - 4127.3
ATGTTGATTGGCGAAGGGTATCGGACTTTCCCTCTCCTGATTTATACCCAATTTATTAGCGAGGTTGGAGGAAATTC
TGCTTTTGCAATTATGGCGATTATCATTGCCTTGGCAATTTTCCTTATCCAAAAACACATTGCAAACCGCTACACTT
TCAGCATGAATCTGCTCCATCCAATTGAGCCTAAAAAAACTACAAAAGGAAAAATGGCTGCCATTTATGCAACAGTC
TACGGAATTATCTTTATCTCTGTTTTACCTCAAATCTACTTAATTTATACCTCTTTCCTAAAAACATCAGGTATGGT
ATCTGTTAAAGGTTATTCTCCAAACAGTTACAAGGTAGCTTTCCATCGTATGGGATCTGCTATTTTCAATACCATTC
GTATCCCTTTGATTGCCTTAGTTCTAGTTGTTCTATTTGCGACATTTATCTCCTACCTAGCCCTTAGAAAACGGAAT
TTGTTTACAAACTTAATTGACAGCCTCAGTATGGTACCTTATATTGTACCAGGAACCGTTCTAGGGATTGCCTTCAT
TTCTTCCTTCAATACTGGTCTATTTGGAAGTGGATTTCTTATGATTACAGGGACTGCTTTCATCTTGATTATGTCTC
TATCTGCCAGAAGATTACCTTATACTATTCGCTCATCTGTTGCTAGCTTACAACAAATAGCACCAAGTATTGAAGAA
GCTGCTGAAAGCTTAGGAAGTAGTCGTCTCAATACCTTTGCTAAGATTACAACTCCAATGATGCTATCTGGTATCAT
TTCTGGAGCCATCTTATCTTGA
MLIGEGYRTFPVLIYTQFISEVGGNSAFAIMAIIIALAIFLIQKHIANRYSFSMNLLHPIEPKKTTKGKMAAIYATV
YGIIFISVLPQIYLIYTSFLKTSGMVSVKGYSPNSYKVAFHRMGSAIFNTIRIPLIALVLVVLFATFISYLAVRKRN
LFTNLIDSLSMVPYIVPGTVLGIAFISSFNTGLFGSGFLMITGTAFILIMSLSARRLPYTIRSSVASLQQIAPSIEE
AAESLGSSRLNTFAKITTPMMLSGIISGAILSZ

TABLE 4
ID301
ATGAATAAGAAAAAAATGATTTTAACAAGTCTAGCCAGCGTCGCTATCTTAGGGGCTGGTTTTGTTACGTCTCAGCC
TACTTTTGTAAGAGCAGAAGAATCTCCACAAGTTGTCGAAAAATCTTCATTAGAGAAGAAATATGAGGAAGCAAAAG
CAAAAGCTGATACTGCCAAGAAAGATTACGAAACGGCTAAAAAGAAAGCAGAAGACGCTCAGAAAAAGTATGAAGAT
GATCAGAAGAGAACTGAGGAGAAAGCTCGAAAAGAAGCAGAAGCATCTCAAAAATTGAATGATGTGGCGCTTGTTGT
TCAAAATGCATATAAAGAGTACCGAGAAGTTCAAAATCAACGTAGTAAATATAAATCTGACGCTGAATATCAGAAAA
AATTAACAGAGGTCGACTCTAAAATAGAGAAGGCTAGGAAAGAGCAACAGGACTTGCAAAATAAATTTAATGAAGTA
AGAGCAGTTGTAGTTCCTGAACCAAATGCGTTGGCTGAACTAAGAAAAAAAGCAGAAGAAGCTAAAGCAGAAGAAAA
AGTAGCTAAGAGAAAATATGATTATGCAACTCTAAAGGTAGCACTAGCGAAGAAAGAAGTAGAGGCTAAGGAACTTG
AAATTGAAAAACTTCAATATGAAATTTCTACTTTGGAACAAGAAGTTGCTACTGCTCAACATCAAGTAGATAATTTG
AAAAAACTTCTTGCTGGTGCGGATCCTGATGATGGCACAGAAGTTATAGAAGCTAAATTAAAAAAAGGAGAAGCTGA
GCTAAACGCTAAACAAGCTGAGTTAGCAAAAAAACAAACAGAACTTGAAAAACTTCTTGACAGCCTTGATCCTGAAG
GTAAGACTCAGGATGAATTAGATAAAGAAGCAGAAGAAGCTGAGTTGGATAAAAAAGCTGATGAACTTCAAAATAAA
GTTGCTGATTTAGAAAAAGAAATTAGTAACCTTGAAATATTACTTGGAGGGGCTGATCCTGAAGATGATACTGCTGC
TCTTCAAAATAAATTAGCTGCTAAAAAAGCTGAGTTAGCAAAAAAACAAACAGAACTTGAAAAACTTCTTGACAGCC
TTGATCCTGAAGGTAAGACTCAGGATGAATTAGATAAAGAAGCAGAAGAAGCTGAGTTGGATAAAAAAGCTGATGAA
CTTCAAAATAAAGTTGCTGATTTAGAAAAAGAAATTAGTAACCTTGAAATATTACTTGGAGGGGCTGATTCTGAAGA
TGATACTGCTGCTCTTCAAAATAAATTAGCTACTAAAAAAGCTGAATTGGAAAAAACTCAAAAAGAATTAGATGCAG
CTCTTAATGAGTTAGGCCCTGATGGAGATGAAGAAGAAACTCCAGCGCCGGCTCCTCAACCAGAGCAACCAGCTCCT
GCACCAAAACCAGAGCAACCAGCTCCAGCTCCAAAACCAGAGCAACCAGCTCCTGCACCAAAACCAGAGCAACCAGC
TCCAGCTCCAAAACCAGAGCAACCAGCTCCAGCTCCAAAACCAGAGCAACCAGCTAAGCCGGAGAAACCAGCTGAAG
AGCCTACTCAACCAGAAAAACCAGCCACTCCAAAAACAGGCTGGAAACAAGAAAACGGTATGTGGTATTTCTACAAT
ACTGATGGTTCAATGGCAATAGGTTGGCTCCAAAACAACGGTTCATGGTACTACCTAAACGCTAACGGCGCTATGGC
AACAGGTTGGGTGAAAGATGGAGATACCTGGTACTATCTTGAAGCATCAGGTGCTATGAAAGCAAGCCAATGGTTCA
AAGTATCAGATAAATGGTACTATGTCAACAGCAATGGCGCTATGGCGACAGGCTGGCTCCAATACAATGGCTCATGG
TACTACCTCAACGCTAATGGTGATATGGCGACAGGATGGCTCCAATACAACGGTTCATGGTATTACCTCAACGCTAA
TGGTGATATGGCGACAGGATGGGCTAAAGTCAACGGTTCATGGTACTACCTAAACGCTAACGGTGCTATGGCTACAG
GTTGGGCTAAAGTCAACGGTTCATGGTACTACCTAAACGCTAACGGTTCAATGGCAACAGGTTGGGTGAAAGATGGA
GATACCTGGTACTATCTTGAAGCATCAGGTGCTATGAAAGCAAGCCAATGGTTCAAAGTATCAGATAAATGGTACTA
TGTCAATGGCTTAGGTGCCCTTGCAGTCAACACAACTGTAGATGGCTATAAAGTCAATGCCAATGGTGAATGGGTTT
AA
MNKKKMILTSLASVAILGAGFVTSQPTFVRAEESPQVVEKSSLEKKYEEAKAKADTAKKDYETAKKKAEDAQKKYED
DQKRTEEKARKEAEASQKLNDVALVVQNAYKEYREVQNQRSKYKSDAEYQKKLTEVDSKIEKARKEQQDLQNKFNEV
RAVVVPEPNALAETKKKAEEAKAEEKVAKRKYDYATLKVALAKKEVEAKELEIEKLQYEISTLEQEVATAQHQVDNL
KKLLAGADPDDGTEVIEAKLKKGEAELNAKQAELAKKQTELEKLLDSLDPEGKTQDELDKEAEEAELDKKADELQNK
VADLEKEISNLEILLGGADPEDDTAALQNKLAAKKAELAKKQTELEKLLDSLDPEGKTQDELDKEAEEAELDKKADE
LQNKVADLEKEISNLEILLGGADSEDDTAALQNKLATKKAELEKTQKELDAALNELGPDGDEEETPAPAPQPEQPAP
APKPEQPAPAPKPEQPAPAPKPEQPAPAPKPEQPAPAPKPEQPAKPEKPAEEPTQPEKPATPKTGWKQENGMWYFYN
TDGSMAIGWLQNNGSWYYLNANGAMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNSNGAMATGWLQYNGSW
YYLNANGDMATGWLQYNGSWYYLNANGDMATGWAKVNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDG
DTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWVZ
ID302
ATGTTTGCATCAAAAAGCGAAAGAAAAGTACATTATTCAATTCGTAAATTTAGTGTTGGAGTAGCTAGTGTAGTTGT
TGCCAGTCTTGTTATGGGAAGTGTGGTTCATGCGACAGAGAACGAGGGAGCTACCCAAGTACCCACTTCTTCTAATA
GGGCAAATGAAAGTCAGGCAGAACAAGGAGAACAACCTAAAAAACTCGATTCAGAACGAGATAAGGCAAGGAAAGAG
GTCGAGGAATATGTAAAAAAAATAGTGGGTGAGAGCTATGCAAAATCAACTAAAAAGCGACATACAATTACTGTAGC
TCTAGTTAACGAGTTGAACAACATTAAGAACGAGTATTTGAATAAAATAGTTGAATCAACCTCAGAAAGCCAACTAC
AGATACTGATGATGGAGAGTCGATCAAAAGTAGATGAAGCTGTGTCTAAGTTTGAAAAGGACTCATCTTCTTCGTCA
AGTTCAGACTCTTCCACTAAACCGGAAGCTTCAGATACAGCGAAGCCAAACAAGCCGACAGAACCAGGAGAAAAGGT
AGCAGAAGCTAAGAAGAAGGTTGAAGAAGCTGAGAAAAAAGCCAAGGATCAAAAAGAAGAAGATCGTCGTAACTACC
CAACCATTACTTACAAAACGCTTGAACTTGAAATTGCTGAGTCCGATGTGGAAGTTAAAAAAGCGGAGCTTGAACTA
GTAAAAGTGAAAGCTAACGAACCTCGAGACGAGCAAAAAATTAAGCAAGCAGAAGCGGAAGTTGAGAGTAAACAAGC
TGAGGCTACAAGGTTAAAAAAAATCAAGACAGATCGTGAAGAAGCAGAAGAAGAAGCTAAACGAAGAGCAGATGCTA
AAGAGCAAGGTAAACCAAAGGGGCGGGCAAAACGAGGAGTTCCTGGAGAGCTAGCAACACCTGATAAAAAAGAAAAT
GATGCGAAGTCTTCAGATTCTAGCGTAGGTGAAGAAACTCTTCCAAGCCCATCCCTGAAACCAGAAAAAAAGGTAGC
AGAAGCTGAGAAGAAGGTTGAAGAAGCTAAGAAAAAAGCCGAGGATCAAAAAGAAGAAGATCGCCGTAACTACCCAA
CCAATACTTACAAAACGCTTGAACTTGAAATTGCTGAGTCCGATGTGGAAGTTAAAAAAGCGGAGCTTGAACTAGTA
AAAGAGGAAGCTAAGGAACCTCGAAACGAGGAAAAAGTTAAGCAAGCAAAAGCGGAAGTTGAGAGTAAAAAAGCTGA
GGCTACAAGGTTAGAAAAAATCAAGACAGATCGTAAAAAAGCAGAAGAAGAAGCTAAACGAAAAGCAGCAGAAGAAG
ATAAAGTTAAAGAAAAACCAGCTGAACAACCACAACCAGCGCCGGCTCCAAAAGCAGAAAAACCAGCTCCAGCTCCA
AAACCAGAGAATCCAGCTGAACAACCAAAAGCAGAAAAACCAGCTGATCAACAAGCTGAAGAAGACTATGCTCGTAG
ATCAGAAGAAGAATATAATCGCTTGACTCAACAGCAACCGCCAAAAACTGAAAAACCAGCACAACCATCTACTCCAA
AAACAGGCTGGAAACAAGAAAACGGTATGTGGTACTTCTACAATACTGATGGTTCAATGGCGACAGGATGGCTCCAA
AACAATGGCTCATGGTACTACCTCAACAGCAATGGCGCTATGGCGACAGGATGGCTCCAAAACAATGGTTCATGGTA
CTATCTAAACGCTAATGGTTCAATGGCAACAGGATGGCTCCAAAACAATGGTTCATGGTACTACCTAAACGCTAATG
GTTCAATGGCGACAGGATGGCTCCAATACAATGGCTCATGGTACTACCTAAACGCTAATGGTTCAATGGCGACAGGA
TGGCTCCAATACAATGGCTCATGGTACTACCTAAACGCTAATGGTGATATGGCGACAGGTTGGGTGAAAGATGGAGA
TACCTGGTACTATCTTGAAGCATCAGGTGCTATGAAAGCAAGCCAATGGTTCAAAGTATCAGATAAATGGTACTATG
TCAATGGCTCAGGTGCCCTTGCAGTCAACACAACTGTAGATGGCTATGGAGTCAATGCCAATGGTGAATGGGTAAAC
TAA
MFASKSERKVHYSIRKFSVGVASVVVASLVMGSVVHATENEGATQVPTSSNRANESQAEQGEQPKKLDSERDKARKE
VEEYVKKIVGESYAKSTKKRHTITVALVNELNNIKNEYLNKIVESTSESQLQILMMESRSKVDEAVSKFEKDSSSSS
SSDSSTKPEASDTAKPNKPTEPGEKVAEAKKKVEEAEKKAKDQKEEDRRNYPTITYKTLELEIAESDVEVKKAELEL
VKVKANEPRDEQKIKQAEAEVESKQAEATRLKKIKTDREEAEEEAKRRADAKEQGKPKGRAKRGVPGELATPDKKEN
DAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKKKAEDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELV
KEEAKEPRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPKAEKPAPAP
KPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQ
NNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNGSWYYLNANGSMATG
WLQYNGSWYYLNANGDMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVNZ
ID303
ATGGTAAAAAGACGTATAAGGAGAGGGACGAGAGAACCTGAAAAAGTTGTTGTTCCTGAGCAATCATCTATTCCTTC
GTATCCTGTATCTGTTACATCTAACCAAGGAACAGATGTAGCAGTAGAACCAGCTAAAGCAGTTGCTCCAACAACAG
ACTGGAAACAAGAAAATGGTATGTGGTATTTTTATAATACTGATGGTTCCATGGCAACAGGTTGGGTACAAGTTAAT
AGTTCATGGTACTACCTCAACAGCAACGGTTCTATGAAAGTCAATCAATGGTTCCAAGTTGGTGGTAAATGGTATTA
TGTAAATACATCGGGTGAGTTAGCGGTCAATACAAGTATAGATGGCTATAGAGTCAATGATAATGGTGAATGGGTGC
GTTAA
MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPAKAVAPTTDWKQENGMWYFYNTDGSMATGWVQVN
SSWYYLNSNGSMKVNQWFQVGGKWYYVNTSGELAVNTSIDGYRVNDNGEWVRZ
ID304
CTGAATACAAGTTTTGTTCATGCTGCTGATGGGATTCAATATGTCAGAGATGATACTAGAGATAAAGAAGAGGGAAT
AGAGTATGATGACGCTGACAATGGGGATATTATTGTAAAAGTAGCGACTAAACCTAAGGTAGTAACCAAGAAAATTT
CAAGTACGCGAATTCGTTATGAAAAAGATGAAACAAAAGACCGTAGTGAAAATCCTGTTACAATTGATGGAGAGGAT
GGCTATGTAACTACGACAAGGACCTACGATGTTAATCCAGAGACTGGTTATGTTACCGAACAGGTTACTGTTGATAG
AAAAGAAGCCACGGATACAGTTATCAAAGTTCCAGCTAAAAGCAAGGTTGAAGAAGTTCTTGTTCCATTTGCTACTA
AATATGAAGCAGACAATGACCTTTCTGCAGGACAGGAGCAAGAGATTACTCTAGGAAAGAATGGGAAAACAGTTACA
ACGATAACTTATAATGTAGATGGAAAGAGTGGACAAGTAACTGAGAGTACTTTAAGTCAAAAAAAAGACTCTCAAAC
AAGAGTTGTTAAAAAAAGAACCAAGCCCCAAGTTCTTGTCCAAGAAATTCCAATCGAAACAGAATATCTCGATGGCC
CAACTCTTGATAAAAGTCAAGAAGTAGAAGAAGTAGGAGAAATTGGTAAATTACTCTTACTACAATCTATACTGTAG
LNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGED
GYVTTTRTYDVNPETGYVTEQVTVDRKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVT
TITYNVDGKSGQVTESTLSQKKDSQTRVVKKRTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVGEIGKLLLLQSILZ
ID305
ATGAAGCTTTTGAAAAAAATGATGCAAATCGCACTAGCCACATTTTTCTTCGGTTTGTTAGCGACAAATACAGTATT
TGCAGATGATTCTGAAGGATGGCAGTTTGTCCAAGAAAATGGTAGAACCTACTACAAAAAGGGGGATCTAAAAGAAA
CCTACTGGAGAGTGATAGATGGGAAGTACTATTATTTTGATCCTTTATCCGGAGAGATGGTTGTCGGCTGGCAATAT
ATACCTGCTCCACACAAGGGGGTTACGATTGGTCCTTCTCCAAGAATAGAGATTGCTCTTAGACCAGATTGGTTTTA
TTTTGGTCAAGATGGTGTATTACAAGAATTTGTTGGCAAGCAAGTTTTAGAAGCAAAAACTGCTACGAATACCAACA
AACATCATGGGGAAGAATATGATAGCCAAGCAGAGAAACGAGTCTATTATTTTGAAGATCAGCGTAGTTATCATACT
TTAAAAACTGGTTGGATTTATGAAGAGGGTCATTGGTATTATTTACAGAAGGATGGTGGCTTTGATTCGCGCATCAA
CAGATTGACGGTTGGAGAGCTAGCACGTGGTTGGGTTAAGGATTACCCTCTTACGTATGATGAAGAGAAGCTAAAAG
CAGCTCCATGGTACTATCTAAATCCAGCAACTGGCATTATGCAAACAGGTTGGCAATATCTAGGTAATAGATGGTAC
TACCTCCATTCGTCAGGAGCTATGGCAACTGGCTGGTATAAGGAAGGCTCAACTTGGTACTATCTAGATGCTGAAAA
TGGTGATATGAGAACTGGCTGGCAAAACCTTGGGAACAAATGGTACTATCTCCGTTCATCAGGAGCTATGGCAACTG
GTTGGTATCAGGAAAGTTCGACTTGGTACTATCTAAATGCAAGTAATCGAGATATGAAAACAGGCTGGTTCCAAGTC
AATGGTAACTGGTACTATGCCTATGATTCAGGTGCTTTAGCTGTTAATACCACAGTAGGTGGTTACTACTTAAACTA
TAATGGTGAATGGGTTAAGTAA
MKLLKKMMQIALATFFFGLLATNTVFADDSEGWQFVQENGRTYYKKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQY
IPAPHKGVTIGPSPRIEIALRPDWFYFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHT
LKTGWIYEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLNPATGIMQTGWQYLGNRWY
YLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRSSGAMATGWYQESSTWYYLNASNGDMKTGWFQV
NGNWYYAYDSGALAVNTTVGGYYLNYNGEWVKZ
ID306
TTGGCTGGTAGATATGGTTCTGCTGTTCAGTGTACAGAAGTGACTGCCTCAAACCTTTCAACACTTAAAACTAAAGC
TACGGTTGTAGAAAAACCACTGAAAGATTTTAGAGCGTCTACGTCTGATCAGTCTGGTTGGGTGGAATCTAATGGTA
AATGGTATTTCTATGAGTCTGGTGATGTGAAGACAGGTTGGGTGAAAACAGATGGTAAATGGTACTATTTGAATGAC
TTAGGTGTCATGCAGACTGGATTTGTAAAATTTTCTGGTAGCTGGTATTACTTGAGCAATTCAGGTGCTATGTTTAC
AGGCTGGGGAACAGATGCTAGCAGATGGTTCTACTTTGACGGCTCAGGAGCTATGAAGACAGGCTGGTACAAGGAAA
ATGGCACTTGGTATTACCTTGACGAAGCAGGTATCATGAAGACAGGTTGGTTTAAAGTCGGACCACACTGGTACTAT
GCCTACGGTTCAGGAGCTTTGGCTGTGAGCACAACAACACCAGATGGTTACCGTGTAAATGGTAATGGTGAATGGGT
AAACTAG
LAGRYGSAVQCTEVTASNLSTVKTKATVVEKPLKDFRASTSDQSGWVESNGKWYFYESGDVKTGWVKTDGKWYYLND
LGVMQTGFVKFSGSWYYLSNSGAMFTGWGTDGSRWFYFDGSGAMKTGWYKENGTWYYLDEAGIMKTGWFKVGPHWYY
AYGSGALAVSTTTPDGYRVNGNGEWVNZ
ID307
ATGAAAATTTTGAAAAAAACTATGCAAGTTGGACTGACAGTATTTTTCTTTGGTTTGCTAGGGACCAGTACAGTATT
TGCAGATGATTCTGAAGGATGGCAGTTTGTCCAAGAAAACGGAAGAACCTACTACAAAAAGGGGGACCTCAAAGAAA
CCTACTGGCGAGTGATTGATGGTAAGTACTATTATTTTGATTCTCTATCTGGAGAGATGGTTGTCGGCTGGCAATAT
ATCCCGTTTCCATCTAAAGGTAGTACAATTGGTCCTTACCCAAATGGTATCAGATTAGAAGGTTTTCCAAAGTCAGA
GTGGTACTACTTCGATAAAAATGGAGTGCTACAAGAGTTTGTTGGTTGGAAAACATTAGAGATTAAAACTAAAGACA
GTGTTGGAAGAAAGTACGGGGAAAAACCTGAAGATTCAGAAGATAAAGAAGAGAAGCGTTATTATACGAACTATTAC
TTTAATCAAAATCATTCTTTAGAGACAGGTTGGCTTTATGATCAGTCTAACTGGTATTATCTAGCTAAGACGGAAAT
TAATGGAGAAAACTACCTTGGTGGTGAAAGACGTGCGGGCTGGATAAACGATGATTCGACTTGGTACTACCTAGATC
CAACAACTGGTATTATGCAAACAGGTTGGCAATATCTAGGTAATAAGTGGTACTACCTCCGTTCCTCAGGAGCAATG
GCCACTGGCTGGTATCAGGAAGGTACCACTTGGTATTATTTAGACCACCCAAATGGCGATATGAAAACAGGTTGGCA
AAACCTTGGGAACAAATCGTACTATCTCCCTTCATCAGGAGCTATGGCAACTGGTTGGTATCAAGATGGTTCAACTT
GGTACTACCTAAATGCACGTAATGGAGACATGAAGACAGGTTGGTTCCAGGTCAATGGCAACTGGTACTATGCTTAT
AGCTCAGGTGCTTGGCAGTGAATACGACCGTAGATGGCTATTCTGTCAACTATAATGGCGAATGGCTTCGGTAA
MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYYKKGDLKETYWRVIDGKYYTFDSLSGEMVVGWQY
IPFPSKGSTIGPYPNGIRLEGFPKSEWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYY
FNQNHSLETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYLGNKWYYLRSSGAM
ATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAY
SSGALAVNTTVDGYSVNYNGEWVRZ
ID308
ATGAAAAAGAAATTAACTAGTTTAGCACTTGTAGGCGCTTTTTTAGGTTTGTCATGGTATGGGAATGTTCAGGCTCA
AGAAAGTTCAGGAAATAAAATCCACTTTATCAATGTTCAAGAAGGTGGCAGTGATGCGATTATTCTTGAAAGCAATG
GACATTTTGCCATGGTGGATACAGGAGAAGATTATGATTTCCCAGATGGAAGTGATTCTCGCTATCCATGGAGAGAA
GGAATTGAAACGTCTTATAAGCATGTTCTAACAGACCGTGTCTTTCGTCGTTTGAAGGAATTGGGTGTCCAAAAACT
TGATTTTATTTTGGTGACCCATACCCACAGTGATCATATTGGAAATGTTGATGAATTACTGTCTACCTATCCAGTTG
ACCGAGTCTATCTTAAGAAATATAGTGATAGTCGTATTACTAATTCTGAACGTCTATGGGATAATCTGTATGGCTAT
GATAAGGTTTTACAGACTGCTGCAGAAAAAGGTGTTTCAGTTATTCAAAATATCACACAAGGGGATGCTCATTTTCA
GTTTGGGGACATGGATATTCAGCTCTATAATTATGAAAATGAAACTGATTCATCGGGTGAATTAAAGAAAATTTGGG
ATGACAATTCCAATTCCTTGATTAGCGTGGTGAAAGTCAATGGCAAGAAAATTTACCTTGGGGGCGATTTAGATAAT
GTTCATGGAGCAGAAGACAAGTATGGTCCTCTCATTGGAAAAGTTGATTTGATGAAGTTTAATCATCACCATGATAC
CAACAAATCAAATACCAAGGATTTCATTAAAAATTTGAGTCCGAGTTTGATTGTTCAAACTTCGGATAGTCTACCTT
GGAAAAATGGTGTTGATAGTGAGTATGTTAATTGGCTCAAAGAACGAGGAATTGAGAGAATCAACGCAGCCAGCAAA
GACTATGATGCAACAGTTTTTGATATTCGAAAAGACGGTTTTGTCAATATTTCAACATCCTACAAGCCGATTCCAAG
TTTTCAAGCTGGTTGGCATAAGAGTGCATATGGGAACTGGTGGTATCAAGCGCCTGATTCTACAGGAGAGTATGCTG
TCGGTTGGAATGAAATCGAAGGTGAATGGTATTACTTTAACCAAACGGGTATCTTGTTACAGAATCAATGGAAAAAA
TGGAACAATCATTGGTTCTATTTGACAGACTCTGGTGCTTCTGCTAAAAATTGGAAGAAAATCGCTGGAATCTGGTA
TTATTTTAACAAAGAAAACCAGATGGAAATTGGTTGGATTCAAGATAAAGAGCAGTGGTATTATTTGGATGTTGATG
GTTCTATGAAGACAGGATGGCTTCAATATATGGGGCAATGGTATTACTTTGCTCCATCAGGGGAAATGAAAATGGGC
TGGGTAAAAGATAAAGAAACCTGGTACTATATGGATTCTACTGGTGTCATGAAGACAGGTGAGATAGAAGTTGCTGG
TCAACATTATTATCTGGAAGATTCAGGAGCTATGAAGCAAGGCTGGCATAAAAAGGCAAATGATTGGTATTTCTACA
AGACAGACGGTTCACGAGCTGTGGGTTGGATCAAGGACAAGGATAAATGGTACTTCTTGAAAGAAAATGGTCAATTA
CTTGTGAACGGTAAGACACCAGAAGGTTATACTGTGGATTCAAGTGGTGCCTGGTTAGTGGATGTTTCGATCGAGAA
ATCTGCTACAATTAAAACTACAAGTCATTCAGAAATAAAAGAATCCAAAGAAGTAGTGAAAAAGGATCTTGAAAATA
AAGAAACGAGTCAACATGAAAGTGTTACAAATTTTTCAACTAGTCAAGATTTCAGATCCTCAACTTCACAAAGCTCT
GAAACGAGTGTAAACAAATCGGAATCAGAACAGTAG
MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSDAIILESNGHFAMVDTGEDYDFPDGSDSRYPWRE
GIETSYKHVLTDRVFRRLKELGVQKLDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGY
DKVLQTAAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKVNGKKIYLGGDLDN
VHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQTSDSLPWKNGVDSEYVNWLKERGIERINAASK
DYDATVFDIRKDGFVNISTSYKPIPSFQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKK
WNNHWFYLTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQWYYFAPSGEMKMG
WVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKANDWYFYKTDGSRAVGWIKDKDKWYFLKENGQL
LVNGKTPEGYTVDSSGAWLVDVSIEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSS
ETSVNKSESEQZ
ID309
ATGGAAATTAATGTGAGTAAATTAAGAACAGATTTGCCTCAAGTCGGCGTGCAACCATATAGGCAAGTACACGCACA
CTCAACTGGGAATCCGCATTCAACCGTACAGAATGAAGCGGATTATCACTGGCGGAAAGACCCAGAATTAGGTTTTT
TCTCGCACATTGTTGGGAACGGTTGCATCATGCAGGTAGGACCTGTTGATAATGGTGCCTGGGACGTTGGGGGCGGT
TGGAATGCTGAGACCTATGCAGCGGTTGAACTGATTGAAAGCCATTCAACCAAAGAAGAGTTCATGACGGACTACCG
CCTTTATATCGAACTCTTACGCAATCTAGCAGATGAAGCAGGTTTGCCGAAAACGCTTGATACAGGGAGTTTAGCTG
GAATTAAAACGCACGAGTATTGCACGAATAACCAACCAAACAACCACTCAGACCACGTTGACCCTTATCCATATCTT
GCTAAATGGGGCATTAGCCGTGAGCAGTTTAAGCATGATATTGAGAACGGCTTGACGATTGAAACAGGCTGGCAGAA
GAATGACACTGGCTACTGGTACGTACATTCAGACGGCTCTTATCCAAAAGACAAGTTTGAGAAAATCAATGGCACTT
GGTACTACTTTGACAGTTCAGGCTATATGCTTGCAGACCGCTGGAGGAAGCACACAGACGGCAACTGGTACTGGTTC
GACAACTCAGGCGAAATGGCTACAGGCTGGAAGAAAATCGCTGATAAGTGGTACTATTTCAACGAAGAAGGTGCCAT
GAAGACAGGCTGGGTCAAGTACAAGGACACTTGGTACTACTTAGACGCTAAAGAAGGCGCCATGGTATCAAATGCCT
TTATCCAGTCAGCGGACGGAACAGGCTGGTACTACCTCAAACCAGACGGAACACTGGCAGACAAGCCAGAATTCACA
GTAGAGCCAGATGGCTTGATTACAGTAAAATAA
MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWRKDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGG
WNAETYAAVELIESHSTKEEFMTDYRLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYL
AKWGISREQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLADRWRKHTDGNWYWF
DNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEGAMVSNAFIQSADGTGWYYLKPDGTLADKPEFT
VEPDGLITVKZ
ID310
ATGGGCACAACAGGATTTACAATAATTGACTTAATTATCTTGATTGTTTATTTACTTGCGGTGTTGGTTGCAGGTAT
CTATTTCTCTAAAAAAGAGATGAAAGGAAAAGAGTTCTTTAAAGGAGATGGTTCGGTTCCTTGGTATGTTACTTCGG
TATCCATTTTTGCCACAATGCTCAGTCCGATTTCCTTCTTGGGACTCGCTGGTAGCTCTTATGCAGGTAGCTGGATT
TTATGGTTTGCTCAATTAGGGATGGTAGTAGCTATTCCACTGACAATTCGTTTTATCTTACCTATCTTTGCACGGAT
AGACATCGATACGGCATATGATTACTTGGATAAACGTTTTAATTCTAAAGCACTTCGTATTATTTCAGCACTCTTGT
TTATTATTTATCAATTGGGACGTATGTCTATCATTATGTACCTCCCATCAGCTGGTTTATCAGTATTGACAGGAATT
GACATCAATATTTTGATTATTTTGATGGGTGTAGTTGCAATTGTTTATTCTTATACTGGTGGTCTAAAATCCGTATT
ATGGACAGACTTTATTCAAGGTGTGATTCTGATTAGTGGTGTCGTTTTAGCTTTATTTGTACTGATTGCTAATATTA
AAGGTGGCTTTGGTGCAGTAGCAGAAACATTAGCAAACGGGAAATTCCTTGCTGCAAATGAAAAACTTTTCGATCCT
AACTTGCTTTCAAACTCCATCTTTTTAATTGTGATGGGTTCAGGCTTTACAATCTTGTCTTCCTATGCTTCATCTCA
AGATTTGGTTCAACGTTTTACTACAACACAAAATATTAAGAAACTTAATAAGATGTTCTTCACAAACGGTGTTTTGT
CACTTGCAACTGCAACAGTCTTTTACTTGATTGGTACAGGCTTGTACGTATTCTATCAAGTACAAAATGCAGATAGT
GCAGCTAGCAATATCCCTCAAGACCAAATCTTTATGTACTTTATTGCATACCAGTTACCAGTAGGTATCACAGGTTT
GATCTTGGCAGCGATTTATGCAGCATCTCAATCAACTATTTCAACAGGTTTGAACTCTGTTGCAACTTCATGGACAT
TGGATATTCAAGATGTCATTTCTAAAAATATGTCAGACAATCGTCGTACGAAAATTGCACAATTCGTATCTCTAGCA
GTAGGTTTATTCTCAATTGGTGTTTCCATTGTCATGGCTCACTCAGATATTAAATCTTCATACGAATGGTTCAATAG
TTTCATGGGACTTGTACTTGGTCTACTTGGTGGTGTATTTATTCTTGGATTTGTTTCTAAAAAAGCAAATAAACAAG
GTGCTTATGCAGCGCTGATTGTATCAACCATCGTCATGGTATTTATTAAATACTTCCTTCCTCCAACAGCTGTTAGC
TACTGGGCATATTCATTGATTTCAATCTCTGTATCAGTAGTTTCAGGTTATATTGTATCTGTTCTTACTGGAAATAA
AGTATCTGCACCTAAATATACAACGATTCATGATATTACAGAAATTAAAGCGGATTCAAGTTGGGAAGTTCGTCACT
AA
MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGSVPWYVTSVSIFATMLSPISFLGLAGSSYAGSWI
LWFAQLGMVVAIPLTIRFILPIFARIDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGI
DINILIILMGVVAIVYSYTGGLKSVLWTDFIQGVILISQVVLALVVLIANIKGGFGAVAETLANGKFLAANEKLFDP
NLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKMLFTNGVLSLATATVFYLIGTGLYVFYQVQNADS
AASNIPQDQIFMYFIAYQLPVGITGLILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLA
VGLFSIGVSIVMAMSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMVFIKYFLPPTAVS
YWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSSWEVRHZ
ID311
ATGAAAATTAATAAAAAATATCTAGCAGGTTCAGTGGCAGTCCTTGCCCTAAGTGTTTGTTCCTATGAGCTTGGTCG
TCACCAAGCTGGTCAGGATAAGAAAGAGTCTAATCGAGTTGCTTATATAGATGGTGATCAGGCTGGTCAAAAGGCAG
AAAACTTGACACCAGATGAAGTCAGTAAGAGGGAGGGGATCAACGCCGAACAAATCGTCATCAAGATTACGGATCAA
GGTTATGTGACCTCTCATGGAGACCATTATCATTACTATAATGGCAAGGTCCCTTATGATGCCATCATCAGTGAAGA
GCTCCTCATGAAAGATCCGAATTATCAGTTGAAGGATTCAGACATTGTCAATGAAATCAAGGGTGGTTATGTCATCA
AGGTAGACGGAAAATACTATGTTTACCTTAAGGATGCACCTCATGCGGATAATATTCGGACAAAAGAAGAGATTAAA
CGTCAGAAGCAGGAACGCAGTCATAATCACGGGTCAGGAGCTAACCATCATGCAGTAGCTGCAGCCAGAGCCCAAGG
ACGCTATACAACGGATGATGGGTATATCTTCAATGCATCTGATATCATTGAGGACACGGGTGATGCTTATATCGTTC
CTCACGGCGACCATTACCATTACATTCCTAAGAATGAGTTATCAGCTAGCGACTTAGCTGCTGCAGAAGCCTATTGG
AATGGGAAGCAGGGATCTCGTCCTTCTTCAAGTTCTAGTTATAATGCAAATCCAGCTCAACCAAGATTGTCAGACAA
CCACAATCTGACTGTCACTCCAACTTATCATCAAAATCAACGGGAAAACATTTCAAGCCTTTTACGTGAATTGTATG
CTAAACCCTTATCAGAACGCCATGTCGAATCTGATGGCCTTATTTTCGACCCAGCGCAAATCACAAGTCGAACCGCC
AGAGGTGTAGCTGTCCCTCATGGTAACCATTACCACTTTATCCCTTATGAACAAATCTCTGAATTGGAAAAACGAAT
TGCTCGTATTATTCCCCTTCGTTATCGTTCAAACCATTGGGTACCAGATTCAAGACCAGAACAACCAAGTCCACAAT
CGACTCCGGAACCTAGTCCAAGTCCGCAACCTGCACCAAATCCTCAACCACCTCCAAGCAATCCAATTGATGAGAAA
TTGGTCAAAGAAGCTGTTCGAAAAGTAGGCGATGGTTATGTCTTTGAGGAGAATGGAGTTTCTCGTTATATCCCAGC
CAAGGATCTTTCAGCAGAAACAGCAGCAGGCATTGATAGCAAACTGGCCAAGCAGGAAAGTTTATCTCATAAGCTAG
GAGCTAAGAAAACTGACCTCCCATCTAGTGATCGAGAATTTTACAATAAGGCTTATGACTTACTAGCAAGAATTCAC
CAAGATTTACTTGATAATAAAGGTCGACAAGTTGATTTTGAGGCTTTGGATAACCTGTTGGAACGACTCAAGGATGT
CCCAAGTGATAAAGTCAAGTTAGTGGATGATATTCTTCCCTTCTTAGCTCCGATTCCTCATCCAGAACGTTTAGGAA
AACCAAATGCGCAAATTACCTACACTGATGATGAGATTCAAGTAGCCAAGTTGGCAGGCAAGTACACAACAGAAGAC
GGTTATATCTTTGATCCTCGTGATATAACCAGTGATGAGGGGGATGCCTATGTAACTCCACATATGACCCATAGCCA
CTGGATTAAAAAAGATAGTTTGTCTGAAGCTGAGAGAGCGGCAGCCCAGGCTTATGCTAAAGAGAAAGGTTTGACCC
CTCCTTCGACAGACCATCAGGATTCAGGAAATACTGAGGCAAAAGGAGCAGAAGCTATCTACAACCGCGTGAAAGCA
GCTAAGAAGGTGCCACTTGATCGTATGCCTTACAATCTTCAATATACTGTAGAAGTCAAAAACGGTAGTTTAATCAT
ACCTCATTATGACCATTACCATAACATCAAATTTGAGTGGTTTGACGAAGGCCTTTATGAGGCACCTAAGGGGTATA
CTCTTGAGGATCTTTTGGCGACTGTCAAGTACTATGTCGAACATCCAAACGAACGTCCGCATTCAGATAATGGTTTT
GGTAACGCTAGCGACCATGTTCAAAGAAACAAAAATGGTCAAGCTGATACCAATCAAACGGAAAAACCAAGCGAGGA
GAAACCTCAGACAGAAAAACCTGAGGAAGAAACCCCTCGACAAGAGAAACCGCAAAGCGAGAAACCAGACTCTCCAA
AACCAACAGAGGAACCAGAAGAATCACCAGAGGAATCAGAAGAACCTCAGGTCGAGACTGAAAAGGTTGAAGAAAAA
CTGAGAGAGGCTGAAGATTTACTTGGAAAAATCCAGGATCCAATTATCAAGTCCAATGCCAAAGAGACTCTCACAGG
ATTAAAAAATAATTTACTATTTGGCACCCAGGACAACAATACTATTATGGCAGAAGCTGAAAAACTATTGGCTTTAT
TAAAGGAGAGTAAGTAA
MKINKKYLAGSVAVLALSVCSYELGRHQAGQDKKESNRVAYIDGDQAGQKAENLTPDEVSKREGINAEQIVIKITDQ
GYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIK
RQKQERSHNHGSGANDHAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASELAAAEAYW
NGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSLLRELYAKPLSERHVESDGLIFDPAQITSRTA
RGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEK
LVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIH
QDLLDNKGRQVDFEALDNLLERLKDVPSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTED
GYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKA
AKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGF
GNASDHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEESPEESEEPQVETEKVEEK
LREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESKZ
ID312
ATGGAGGGATTGGTTAGAGTGCATTTATTGCCTGTATTTGGCGATTACAAGCTATCTAAACTTACTACGCCTATTCT
TCAACAGCAAGTAAACAAATGGGCTGACAAGGCAAATAAAGGCGAAAAAGGGGCATTTGCTAACTACTCTTTGCTCC
ATAACATGAATAAGCGTATTTTGAAATATGGCGTAGCTATCCAGGTAATACAATACAACCCAGCTAATGATGTCATC
GTTCCACGCAAACAGCAAAAAGAAAAGGCTGCTGTCAAATACTTAGACAACAAAGAATTAAAACAGTTTCTTGATTA
TTTAGATGCTCTGGATCAATCAAATTATGAGAACTTATTTGATGTTGTTCTGTATAAGACTTTATTGGCCACTGGTT
GCCGTATTAGTGAGGCTCTGGCTCTTGAATGGTCTGATATTGACCTAGAAAGCGGTGTTATCAGCATCAATAAGACA
CTAAACCGCTATCAGGAAATAAACTCACCTAAATCAAGCGCTGGTTATCGTGATATACCAATAGACAAAGCCACATT
ACTTTTACTGAAACAATACAAAAACCGTCAACAAATTCAGTCTTGGAAATTAGGCCGATCTGAAACAGTTGTATTCT
CTGTATTTACGGAGAAATATGCTTATGCTTGTAACTTACGCAAACGCCTAAATAAGCATTTTGATGCTGCTGGAGTA
ACTAACGTATCATTTCATGGTTTCCGCCATACACATACTACTATGATGCTCTATGCTCAGGTTAGCCCGAAAGATGT
TCAGTATAGATTAGGCCACTCTAATTTAATGATCACTGAAAATACTTACTGGCATACTAACCAAGAGAATGCAAAAA
AAGCCGTCTCAAATTATGAAACAGCTATCAACAATTTATAA
MEGLVRVHLLPVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVIQYNPANDVI
VPRKQQKEKAAVKYLDNKELKQFLDYLDALDQSNYENLFDVVLYKTLLATGCRISEALALEWSDIDLESGVISINKT
LNRYQEINSPKSSAGYRDIPIDKATLLLLKQYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGV
TNVSFHGFRHTHTTMMLYAQVSPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAINNLZ

Claims

1. A Streptococcus pneumoniae protein or polypeptide having a sequence selected from those shown in table 2.

2. A Streptococcus pneumoniae protein or polypeptide having a sequence selected from those shown in table 4.

3. A protein or polypeptide as claimed in claim 1 or claim 2 provided in substantially pure form.

4. A protein or polypeptide which is substantially identical to one defined in any one of claims 1 to 3.

5. A homologue or derivative of a protein or polypeptide as defined in any one of claims 1 to 4.

6. An antigenic and/or immunogenic fragment of a protein or polypeptide as defined in Tables 2-4.

7. A nucleic acid molecule comprising or consisting of a sequence which is:

(i) any of the DNA sequences set out in Table 1 or their RNA equivalents;

(ii) a sequence which is complementary of any of the sequences of (i);

(iii) a sequence which codes for the same protein or polypeptide, as those sequences of (i) or (ii);

(iv) a sequence which is substantially identical with any of those of (i), (ii) and (iii);

(v) a sequence which codes for a homologue, derivative or fragment of a protein as defined in Table 1.

8. A nucleic acid molecule comprising or consisting of a sequence which is:

(i) any of the DNA sequences set out in Table 4 or their RNA equivalents;

(ii) a sequence which is complementary to any of the sequences of (i);

(iii) a sequence which codes for the same protein or polypeptide, as those sequences of (i) or (ii);

(iv) a sequence which is substantially identical with any of those of (i), (ii) and (iii);

(v) a sequence which codes for a homologue, derivative or fragment of a protein as defined in Table 4.

9. The use of a protein or polypeptide having a sequence selected from those shown in Tables 2-4, or homologues, derivatives and/or fragments thereof, as an immunogen and/or antigen.

10. An immunogenic and/or antigenic composition comprising one or more proteins or polypeptides selected from those whose sequences are shown in Tables 2-4, or homologues or derivatives thereof, and/or fragments of any of these.

11. An immunogenic and/or antigenic composition as claimed in claim 10 which is a vaccine or is for use in a diagnostic assay.

12. A vaccine as claimed in claim 11 which comprises one or more additional components selected from excipients, diluents, adjuvants or the like.

13. A vaccine composition comprising one or more nucleic acid sequences as defined in Tables 1, 3 or 4.

14. A method for the detection/diagnosis of S. pneumoniae which comprises the step of bringing into contact a sample to be tested with at least one protein or polypeptide as defined in Tables 2-4, or homologues, derivative or fragment thereof.

15. An antibody capable of binding to a protein or polypeptide as defined in Tables 2-4, or for a homologues, derivative or fragment thereof.

16. An antibody as defined in claim 15 which is a monocional antibody.

17. A method of the detection/diagnosis of S. pneumoniae which comprises the step of bringing into contact a sample to be tested and at least one antibody as define din claim 15 or claim 16.

18. A method for the detection/diagnosis of S. pneumoniae which comprises the step of bringing into contact a sample to be tested with at least one nucleic acid sequence as defined in claim 7 or claim 8.

19. A method of determining whether a protein or polypeptide as defined in Tables 2-4 represents a potential anti-microbial target which comprises inactivating said protein or polypeptide and determining whether S. pneumoniae is still viable in vitro or in vivo.

20. The use of an agent capable of antagonising, inhibiting or otherwise interfering with the function or expression of a protein or polypeptide as defined in Tables 2-4 in the manufacture of a medicament for use in the treatment of prophylaxis of S. pneumoniae infection.

21. A method for prophylactic treatment of S. pneumoniae infection comprising delivering to a patient in need thereof an isolated polypeptide comprising the amino acid sequence of SEQ ID NO: 138.

22. The method of claim 21, wherein the agent is a protein or polypeptide formulated as a vaccine which comprises one or more additional components selected from excipients, diluents, adjuvants or the like.

23. The method of claim 21, wherein said polypeptide is encoded by a nucleic acid sequence encoding the amino acid sequence of SEQ ID NO: 138.